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Matches 1 - 50 out of 20,128

Document Document Title
WO/2018/170306A1
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...  
WO/2018/167264A1
The present invention relates to a phenalene-1-one compound, a photosensitizer composition comprising said phenalene-1-one compound, an article comprising said phenalene-1-one compound and/or photosensitizer composition and the use thereof.  
WO/2018/165614A1
Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.  
WO/2018/157232A1
Compositions comprising modulators of N-terminus activation of the androgen receptor, such as EPI-002 and EPI-506, and a second therapeutic agent are provided. Use of such compositions for treatment of various indications, including pros...  
WO/2018/159028A1
The present invention provides an industrially excellent production method by which N-benzyl-2-bromo-3-methoxypropionamide can be safely produced in high yield at lower cost. The production method of the present application comprises, in...  
WO/2018/146285A1
The present invention relates to a method for the production of organo-iodinated compounds, as well as the production intermediates thereof. More specifically, the present invention relates to a method for the production of organo-iodina...  
WO/2018/148721A1
The present invention includes methods and compositions that inhibit AKR1C3 enzymatic activity and consequently reduces androgen receptor (AR) transactivation, AR and prostate specific antigen (PSA) expression levels in, for example, pro...  
WO/2018/143140A1
Through the fusicoccin compound according to the present invention represented by general formula (1A), PPI stabilization effect can be enhanced. [In the formula, Y represents a carbonyl group, a sulfonyl group, or a substituted or unsub...  
WO/2018/141276A1
Disclosed are a novel crystal form of a brivaracetam intermediate compound (I) and preparation method thereof, and a novel crystal form of brivaracetam and preparation method thereof, specifically a crystal form A of a compound I and a c...  
WO/2018/143916A1
The present disclosure is drawn to an acrylamide-containing photo active co-solvent, including a bis-tris propane co-solvent or a polypropylene oxide amine co-solvent modified with an acryloyl group to form the acrylamide-containing phot...  
WO/2018/139607A1
[Problem] To provide a complex which contains a tin ion (Sn2+) or a bismuth ion (Bi3+) with a high purity and is suitable for the production of a lead-free perovskite compound. [Solution] A complex which is represented by general formula...  
WO/2018/138441A1
The invention relates to novel dissymmetric RN,N-dialkylamides of formula (I) in which: R1 represents a linear C1 to C4 alkyl, R2 represents a linear C1 to C10 alkyl, and R3 represents a linear or branched C6 to C15 alkyl, provided that ...  
WO/2018/138369A1
The present invention relates to new malodour-counteracting agents of formula (I) or stereoisomers thereof, particularly useful in blocking the olfactory perception of androstenone, Formula (I), wherein R1, R2, R3,R4, R5, R6, R7 and X ha...  
WO/2018/132899A1
Described herein is a method for treating, preventing, reducing, or delaying onset of, osteosarcoma lung metastasis in a subject, comprising: administering a therapeutically or prophylactically effective amount of a PPARγ agonist, an an...  
WO/2018/135574A1
A method for producing N-(α-hydroxyethyl)formamide which comprises reacting formamide with acetaldehyde in a solvent in the presence of a basic catalyst in a reaction vessel, precipitating the obtained N-(α-hydroxyethyl)formamide in th...  
WO/2018/136014A1
There is provided a formulation comprising a mixture of an organogelator powder and at least one solvent having a relative polarity in the range of 0.3 to 0.6, wherein the organogelator powder comprises a compound of formula (I) as defin...  
WO/2018/132876A1
The present invention relates to novel glycine transport inhibitor compounds and their use for treating pain.  
WO/2018/131575A1
The present invention addresses the problem of providing a novel methylmenthol derivative usable as a cool-sensation imparter or sense-stimulating agent which has none of an undesirable irritating feeling, a peculiar odor, bitterness, an...  
WO/2018/124088A1
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...  
WO/2018/123936A1
The present invention addresses the problem of providing a compound having exceptional light fastness (in particular, a liquid crystal compound having exceptional light fastness), said compound being useable, inter alia, in an optically ...  
WO/2018/118059A1
Disclosed is a novel method for extraction of Oxyresveratrol from Artocarpus hirsutus.  
WO/2018/114484A1
Described is a process for the preparation of a N-[2-(2-pyridinyl)ethyl]carboxamide derivative of general formula (I) or a salt thereof.  
WO/2018/112077A1
Disclosed herein are dihydroceramide desaturase 1 (Des1) inhibitor compounds and compositions, which are useful in the treatment of diseases, such as metabolic, cardiovascular, fibrotic, autoimmune/chronic inflammatory diseases, cystic f...  
WO/2018/107453A1
Provided in the present invention is a curing compound having good solvent solubility and being able to form a cured product having ultra-high heat resistance. The curing compound of the present invention is expressed by the following fo...  
WO/2018/107027A1
Compositions and methods for modulating the immune response in a subject are disclosed.  
WO/2018/105720A1
Provided is a production method for N–(α–hydroxyethyl) formamide, having a step (1) in which a basic catalyst stored in a catalyst supply device and formamide are mixed in a mixing tank; and a step (2) in which the formamide mixed w...  
WO/2018/105724A1
A method for purifying an N-(α-alkoxyethyl)formamide contained in a mixture thereof with a plurality of distillation columns, the plurality of distillation columns being arranged serially, the method including condensing a distillate fr...  
WO/2018/099271A1
The prevent invention provides a method for preparing deuterated chemicals, and deuterated chemicals. The method comprises the step of: making halides undergo a deuteration reaction with a deuterium source under the catalytic action of a...  
WO/2018/095359A1
Disclosed is a tri-functional compound, a preparation method therefor and use thereof. The name of the compound is 1,3,5-tri(4-methylacrylamidophenyl)benzene, and the structural formula is as follows. The tri-functional compound, 1,3,5-t...  
WO/2018/090929A1
Provided is a method for biologically preparing (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine D-mandelate (I), comprising: (a) performing an asymmetric reduction reaction with a compound of formula (VI) as a substrate in the presence of...  
WO/2018/087753A1
The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their int...  
WO/2018/084177A1
A method for producing N-vinylformamide through a vapor-phase thermal decomposition reaction using an evaporator (10) for evaporating a raw material, a thermal decomposition reactor (20) for thermally decomposing a raw material gas gener...  
WO/2018/081018A1
A method is disclosed of treating pain with senicapoc, a potent Ca2+- activated K+ channel, Kca3.1 antagonist in CNS-resident microglia. Senicapoc is shown to cause in a decrease of IL-Ιβ and NO release from microglia cells vivo and in...  
WO/2018/078053A1
The invention relates to mRNA comprising lipid nanoparticles and their medical uses. The lipid nanoparticles of the present invention comprise a cationic lipid according to formula (I), (II) or (III) and/or a PEG lipid according to formu...  
WO/2018/074598A1
Disclosed are: an iron oxide which has the shape of a tube or a rod and contains at least one element selected from the group consisting of aluminum, zirconium, ruthenium, titanium and hafnium so that the elemental ratio of the element i...  
WO/2018/069833A1
The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present inventio...  
WO/2018/070303A1
Provided is a resist underlayer film-forming composition which is capable of providing a resist underlayer film, said resist underlayer film exerting a sufficient anti-reflection function particularly in a KrF process, a high solvent res...  
WO/2018/068295A1
Substituted aryl and heteroaryl ether compounds of the Formula (I) and pharmaceutically acceptable salts thereof, wherein X, R 1, R 2, R 3, L, R 4, L 1, Q, and R 5 are as defined herein. These compounds and pharmaceutically acceptable co...  
WO/2018/068937A1
The invention relates to a method for producing carboxamides of formula (1) by reacting at least one alkyl phenyl carboxylic acid of formula (2) with at least one secondary amine of formula (3), where R1 represents an alkyl group having ...  
WO/2018/065415A1
The present invention relates to a rheology modifier and to its use as thickener in oil-based subterranean treatment fluids; more particularly, the rheology modifier is an aqueous slurry of a pyromellitamide.  
WO/2018/060413A1
The present invention relates to a procatalystcomprising the compound represented by formula Aas an internal electron donor (Formula A), wherein R is hydrogen or a methyl group, N is nitrogen atom; O is oxygen atom; and C is carbon atom....  
WO/2018/062663A1
Provided are: a compound represented by a particular chemical formula; a core-shell dye including a core, which includes the compound, and a shell, which surrounds the core; a photosensitive resin composition including same; and a color ...  
WO/2018/056546A1
Provided are: a compound represented by a particular chemical formula; a core shell dye which comprises a core comprising the compound, and a shell covering the core; a photosensitive resin composition comprising the core-shell dye; and ...  
WO/2018/052936A1
Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone c...  
WO/2018/051042A1
The invention relates to a method for the industrial synthesis of the compound of formula (I).  
WO/2018/052037A1
The present invention addresses the problem of providing a novel branched fluorine-containing compound. The problem is solved by a branched fluorine-containing compound represented by formula (1): [in the formula, L represents a predeter...  
WO/2018/045505A1
Provided are new crystalline forms A, B, C, D, and E of sacubitril sodium salt and a method for preparation thereof, pharmaceutical compositions thereof, and application thereof in preparing drugs for enkephalinase-related diseases.  
WO/2018/041615A1
Processes and systems for producing N-vinyl carboxylic acid amides are provided herein. According to some aspects of the present invention, a process for producing an N-vinyl carboxylic acid amide is described that eliminates interim sol...  
WO/2018/043829A1
Provided are a compound represented by a specific formula, a core-shell dye comprising a core comprising the compound and a shell enclosing the core, a photosensitive resin composition comprising the core-shell dye, and a color filter ma...  
WO/2018/038436A1
The present invention provides a novel diamine compound capable of producing a polymer which exhibits greatly enhanced mechanical properties and heat resistance while maintaining transparency. A film including a polymer produced using th...  

Matches 1 - 50 out of 20,128