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Patent Searching and Data


Matches 1 - 50 out of 20,773

Document Document Title
WO/2020/187155A1
Use of an apocynin dimer analogue derivative in preparing a medicament or a health care product for preventing and treating Parkinson's disease. The structure of the apocynin dimer analogue derivative is as shown in formula I. The apocyn...  
WO/2020/168152A3
Disclosed are compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt or solvate thereof, wherein Q is a 5-membered heterocyclyl or 5-membered heteroaryl having 1 to 4 heteroatoms independently selec...  
WO/2020/185420A1
Provided herein are integrated methods and systems for the production of acrylamide and acrylonitrile compounds and other compounds from at least beta-lactones and/or beta-hydroxy amides.  
WO/2020/181779A1
A method for preparing a lipoamino acid compound on the basis of a deep eutectic solvent, which relates to the field of organic synthesis. A fatty acid and an amino acid are used as substrates and a deep eutectic solvent is used as a med...  
WO/2020/183281A1
This invention provides for a flow synthesis process for producing Oseltamivir and pharmaceutically acceptable salts thereof from shikimic acid in particular but not exclusively to a flow synthesis process for producing Oseltamivir phosp...  
WO/2020/172749A1
Provided herein in aspects is an antibacterial combination comprising a thiopeptide antibiotic and an iron inhibitor. Methods of treatment and/or prevention of bacterial infections using the combination are also provided as well as metho...  
WO/2020/146876A3
This invention is directed to anticancer compounds, pharmaceutical compositions comprising the same, methods of making anticancer compounds, and methods of treating cancer with compounds and pharmaceutical compositions.  
WO/2020/169054A1
The present invention relates to crystalline forms I and II of a (E)-α,β-unsatured amide compound, preparation methods therefor, and uses thereof. The crystalline forms all have excellent properties in physical and chemical stability a...  
WO/2020/168385A1
The present invention relates to a method of preparing N-acyl amino acids selected from N-acyl cysteine compounds, N-acyl serine compounds, N-acyl aspartic acid compounds and N-acyl glutamic acid compounds. The present invention also rel...  
WO/2020/171210A1
The phytol contained in watermelon sprouts is known to have a cancer cell growth inhibiting effect. The problem, however, is the amount ingested to inhibit cancer cell growth is large. A cancer cell growth inhibiting composition having...  
WO/2020/167855A1
Useful processes of preparation and intermediates useful for the preparation of Compound 1, a selective estrogen receptor alpha (ERα) modulator/degrader (SERM/SERD), having utility for the treatment of ER+ cancers including breast cance...  
WO/2020/168152A2
Disclosed are compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt or solvate thereof, wherein Q is a 5-membered heterocyclyl or 5-membered heteroaryl having 1 to 4 heteroatoms independently selec...  
WO/2020/161743A1
The present disclosure relates to an improved process for the preparation of bedaquiline fumarate, comprising a step of preparing bedaquiline by reaction of 3-benzyl-6-bromo-2-methoxyquinoline 5 with 3-(dimethylamino)-l-(naphthalen-l-yl)...  
WO/2020/161275A1
The present invention relates to novel, optionally substituted, N-benzyl-2- phenoxybenzamide derivatives of formula (I), as modulators of EP4 and/or EP2 receptors of prostaglandin E2 (PGE2), to processes for their preparation, to pharmac...  
WO/2020/159797A1
Compounds and compositions including stereoisomers of 6-phenylhexanamide derivative small molecule mitofusin activators are described. In particular, mitofusin activators comprising derivatives of (trans-4-hydroxylcyclohexyl)-6-phenylhex...  
WO/2020/157126A1
The present invention relates to a class of novel compounds of general formula (I), their use as medicaments and pharmaceutical compositions comprising them. Specifically, the compounds of the invention are useful as voltage-gated potass...  
WO/2020/157189A1
The present invention includes name compounds of general formula (I) in which R1, Y, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical composi...  
WO/2020/156312A1
The present invention relates to a polycyclic derivative modulator, a preparation method therefor and an application thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation me...  
WO/2020/159167A1
The present invention provides a method for recovering amide-based compounds, wherein, before a distillation step for separating and recovering amide-based compounds from waste liquid including amide-based compounds such as N-methyl-2-py...  
WO/2020/160464A1
A TRPM8 antagonist is provided that comprises the following the formula (I) described herein. In the formula (I), R1 is selected from a cycloalkyl, a bicycloalkyl, or a tricycloalkyl group. Each R1 group has 5 to 12 carbon atoms. Further...  
WO/2020/116589A9
The purpose of the present disclosure is to provide a novel method for producing a fluorovinyl amide compound. The purpose is achieved by means of a method for producing a compound represented by formula (I) [in the formula, Rf is -F or ...  
WO/2020/118265A3
Compounds that inhibit the activity of Signal transducer and activator of transcription 3 (STAT3), or pharmaceutically acceptable salts or prodrugs thereof, and methods of using these compounds to treat cancer and other diseases.  
WO/2020/152226A1
The present invention relates to a polymorphic form of (S,S)-2-N(3-O-(propan-2-ol)-1-propyl- 4-hydroxybenzene)-3-phenylpropylamide or synonymously named N-[2-(4-Hydroxy-phenyl)- -(2-hydroxy-propoxymethyl)-ethyl]-3-phenyl-propionamide and...  
WO/2020/147582A1
Provided are an amide derivative substituted by cycloalkyl, a preparation method for the amide derivative, and a use in medicine. Specifically, provided are a compound of formula (I), or a pharmaceutically acceptable salt or stereisomer ...  
WO/2020/149129A1
The purpose of the present invention is to produce an asymmetric compound from an oxalyl halide in a simple manner and with high selectivity. The method comprises: a first step of mixing a first raw material selected from ammonia, a mo...  
WO/2020/148760A1
The invention generally concerns a novel class of CB 1 receptor binding molecules and uses thereof.  
WO/2020/076274A3
The present invention is related to unique caffeic acid phenethyl ester (CAPE) analogues, methods for preparation of said molecules, and the usage of said unique molecules in the preparation of a pharmaceutical composition that is to be ...  
WO/2020/146771A1
The present application provides anandamide and 2-arachidonyl glycerol compounds useful for treating a disease or disorder in a subject in need thereof. Pharmaceutical compositions comprising the compounds and methods of treating disease...  
WO/2020/142865A1
Disclosed in the present invention are a Benzamide compound, intermediates, a preparation method, and an application. The present invention provides a Benzamide compound as represented by formula I, and pharmaceutically acceptable salts,...  
WO/2020/102901A8
Provided herein are synthetic compounds useful for inhibiting bacterial growth and uses thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium...  
WO/2020/142745A1
The invention relates to treatment of graft versus host disease (GVHD) or neoplastic disease using compounds that inhibit Rho-associated protein kinases. In preferred aspects, the present invention provides methods for the treatment of c...  
WO/2020/141927A1
The present specification relates to an adamantanecarboxylic acid benzyl amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, and a skin whitening composition c...  
WO/2020/138011A1
The present invention addresses the problem of providing a compound which has a retinoic acid receptor agonist activity and is useful as a medicine that is capable of treating and/or preventing a retinal degenerative disease. The compoun...  
WO/2020/137951A1
The present invention relates to: a composition for producing an N-vinyl carboxylic acid amide, the composition comprising component (A) which is an N-(1-alkoxy ethyl)carboxylic acid amide and component (B) which is an N-(1-alkoxy ethyl)...  
WO/2019/090085A8
Provided herein are compounds of formula (I), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions. (Formula I).  
WO/2020/135560A1
An acetylsalicylic acid derivative and an application thereof. The present invention relates to the field of chemical pharmaceuticals, and in particular, to a compound shown in formula (I) or pharmaceutically acceptable salts thereof. (I)  
WO/2020/127237A1
N-acylglucamide compound of the formula (I) where R2 is a linear or branched alkyl group or an aryl group; X is a moiety R1, which is a linear or branched alkyl group comprising 8 to 18, carbon atoms, which is substituted by one hydroxy ...  
WO/2020/123414A1
The invention relates to the compound (S)-n-hydroxy-2-(2-(4-methoxyphenyl) butanamido)thiazole-5-carboxamide, which is a novel histone deacetylase inhibitor. The invention further relates to the use of the compound for the inhibition of ...  
WO/2020/116589A1
The purpose of the present disclosure is to provide a novel method for producing a fluorovinyl amide compound. The purpose is achieved by means of a method for producing a compound represented by formula (I) [in the formula, Rf is -F or ...  
WO/2020/115753A1
The present invention provides conjugates comprising a sugar such as mannitol and one or more L-DOPA and/or DOPA decarboxylse inhibitors including, inter alia, L- DOPA, carbidopa, benserazide, or a combination thereof, wherein the sugar ...  
WO/2020/115715A1
The present disclosure provides compounds represented by Formula I: I, and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, and R13 are as defined as set forth in the ...  
WO/2020/112605A1
Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful for treating chronic bacterial infections. Also disclosed are pharmaceutical compositions comprising one or more compounds of the invention and a pha...  
WO/2020/111178A1
An alcohol compound represented by formula [A] is provided. (In formula [A], R43 and R44 each independently represent an alkyl group having 1-27 carbon atoms and R45 represents a hydrogen atom or an alkyl group having 1-25 carbon atoms, ...  
WO/2020/109613A1
The invention relates to specific quaternary amidoamine detergents, the process to make them, and their use. The quaternary amidoamine detergents are obtainable by reacting a multifunctional acid with an amino amine, followed by quaterni...  
WO/2020/110615A1
Provided is a raw material feeder that can be operated stably and continuously over a long period, that supplies a raw material to a plurality of evaporation tubes in a falling film evaporator at a steady raw material distribution thereb...  
WO/2020/110614A1
Provided is a method for producing N-vinylcarboxylic amide capable of suppressing blockage problems of a pyrolysis reactor caused by resins and also capable of operating stably and continuously over an extended period of time. A method f...  
WO/2020/109638A1
The present invention relates to a multivariant metal–organic hybrid network formed by two different metals (M1 and M2) with at least two different oxamide ligands derived from at least two amino acids. The invention also relates to th...  
WO/2020/103859A1
The invention provides amides that inhibit cellular necrosis including corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositi...  
WO/2020/106780A1
Provided herein are compounds or payloads, linker-payloads, antibody-drug conjugates, and compositions, and methods for the treatment of diseases and disorders associated with the liver X receptor, including bis-octahydrophenanthrene car...  
WO/2020/102901A1
Provided herein are synthetic compounds useful for inhibiting bacterial growth and uses thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium...  

Matches 1 - 50 out of 20,773