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WO/2010/043711A1 |
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, ph...
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WO/2010/042652A2 |
Described herein are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in ...
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WO/2010/041978A1 |
The invention relates to an improved method for the industrial preparation of ammonium salts of fumaric or succinic acid, said salts being used for producing biologically active additives or medicines, as well as in the veterinary and fo...
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WO/2010/039451A1 |
An improved process for the manufacture of technical grade (meth)acrylic acid, e.g., acrylic acid, the process comprising producing a hydrated reaction product from the gas-phase oxidation of at least one (meth)acrylic acid precursor, e....
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WO/2010/039531A1 |
The invention relates to novel resolvin compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel resolvin compounds of the invention.
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WO/2010/038676A1 |
A catalyst for producing acrylic acid by catalytically oxidizing propane and/or acrolein in a vapor phase with a gas comprising molecular oxygen. The catalyst is characterized by containing an active catalyst ingredient comprising molyb...
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WO/2010/038677A1 |
A catalyst for producing acrolein and/or acrylic acid by catalytically oxidizing propylene in a vapor phase with a gas comprising molecular oxygen. The catalyst is characterized by containing an active catalyst ingredient comprising mol...
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WO/2010/032665A1 |
A fixed bed reactor which comprises a first stage catalyst layer packed with a first stage catalyst for producing acrolein from propylene, a second stage catalyst layer packed with a second stage catalyst for producing acrylic acid from ...
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WO/2010/008735A9 |
The present invention provides crystalline and amorphous salts of O- desmethylvenlafaxine and processes for preparing said salts of O- desmethylvenlafaxine. The present invention further provides pharmaceutical compositions comprising sa...
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WO/2010/032990A1 |
The present invention provides a fluorine-based compound and a coating composition and a film including the same. By using the fluorine-based compound according to the present invention, a film having excellent functionalities of water r...
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WO/2010/031949A1 |
The present invention relates to the production of bio-resourced polymer-grade acrylic acid, the grade being defined by a minimum 14C content and by limiting thresholds for impurity contents that could be detrimental to polymerisation me...
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WO/2010/027732A1 |
A process for the preparation of acrolein and or acrylic acid from propane, in which the propane is subjected, in a first reaction stage, to a partial oxydehydrogenation with molecular oxygen under homogeneous and/or heterogeneous cataly...
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WO/2010/025374A2 |
Methods of increasing the total lipid content in a eukaryotic cell, the total content of polyunsaturated fatty acids [PUFAs], and/or the ratio of desaturated fatty acids to saturated fatty acids by reducing the activity of the heterotrim...
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WO/2010/023053A2 |
The present invention relates to a process for preparing unsaturated aldehydes or unsaturated carboxylic acids by heterogeneous catalytic gas phase oxidation of unsaturated or saturated hydrocarbons, comprising the process steps of: i) p...
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WO/2010/020368A1 |
The invention relates to a method for producing unsaturated alpha, omega dicarboxylic acids and/or alpha, omega dicarboxylic acid diesters with the help of two ruthenium complex catalysts. Unsaturated alpha, omega dicarboxylic acids and/...
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WO/2010/020719A1 |
The present invention relates to the compound of formula (I) and to the use thereof as an intermediate for the synthesis of the compound of formula (A) or pharmaceutically acceptable salts thereof: formulae (II).
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WO/2010/016493A1 |
A method for producing (meth)acrylic acid anhydride by reacting (meth)acrylic acid with a fatty acid anhydride, which can highly efficiently produce (meth)acrylic acid anhydride with high yield, while suppressing a side reaction. The me...
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WO/2010/012650A1 |
There is provided novel compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions suc...
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WO/2010/012471A1 |
The present invention relates to salts of tramadol and ibuprofen, their crystal form, processes for preparation of the same and their uses as medicaments, more particularly for the treatment of pain.
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WO/2010/013749A1 |
Disclosed is a catalyst for methacrylic acid production that can produce methacrylic acid with high selectivity. Also disclosed are a process for producing the catalyst and a process for producing methacrylic acid using the catalyst. A...
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WO/2010/012775A1 |
The present invention discloses novel and useful intermediates for the synthesis of ezetimibe (EZT), which intermediates share a characteristic Z-isomeric structure. Based on Z-5-(4-fluorophenyl)-pent-4-enoic acid, and proceeding the syn...
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WO/2010/010291A2 |
The invention relates to vinyl propionate in which at least part of the carbon atoms is from a renewable source. The invention also relates to a method for producing vinyl propionate, and to the copolymers, compositions and uses of vinyl...
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WO/2010/010298A2 |
The invention relates to a method for producing bioresourced propionic acid from glycerol. The invention also relates to a composition comprising more than 85 mass % of bioresourced propionic acid, and to the use of the propionic acid ob...
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WO/2010/010464A2 |
Provided herein is an impurity of fesoterodine, fesoterodine dehydroxy impurity, 2-[(lR)-3- [bis(l-methylethyl)amino]-l-phenylpropyl]-4-methylphenyl isobutyrate, and a process for preparing and isolating thereof. Provided further herein ...
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WO/2010/007139A1 |
The present invention relates to a process for the oxidation of alcohol and/or aldehyde groups with a peroxo compound in the presence of a heterogeneous rhenium based catalyst, and a co-catalyst. The process of the invention may, for exa...
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WO/2010/007327A2 |
The present application relates to a process for manufacturing maleic anhydride that comprises the following steps: a) fermentation of renewable raw materials and optionally purification to produce a mixture comprising at least butanol; ...
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WO/2010/001103A1 |
There is described a process for the manufacture of a racemic 2-aryl propionic acid compound, or a pharmaceutically acceptable salt thereof, which comprises reacting the S- or R- enantiomer of the corresponding 2-aryl propionic acid comp...
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WO/2009/149808A1 |
The invention relates to a method for producing maleic anhydride by catalytic gas phase oxidation of butane with oxygen, the reaction being carried out under adiabatic conditions in 10 to 60 reaction zones that are arranged in series. Th...
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WO/2009/149797A1 |
The invention relates to a process for preparing a compound according to formula (I). The invention also relates to useful intermediates in the process.
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WO/2009/149809A1 |
The invention relates to a method for producing formaldehyde by catalytic gas phase oxidation of methanol with oxygen, the reaction being carried out under adiabatic conditions on 10 to 60 catalyst beds that are arranged in series. The i...
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WO/2009/147687A2 |
The present patent application relates to an improved process for the separation of enantiomerically pure compounds. Specifically it relates to separation of enantiomerically pure Rivastigmine, Duloxetine, Escitalopram and their intermed...
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WO/2009/147965A1 |
Provided is a catalyst which can prevent a lowering in selectivity for a target product in a gas-phase catalytic reaction and has an excellent frictional resistance. A catalyst which is a supported catalyst comprising an inert support th...
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WO/2009/148105A1 |
Disclosed is an acrolein manufacturing method having a glycerol dehydration reaction step (1) in which glycerol is dehydrated by reacting in the presence of a copper compound and a heteroatom compound, a step (2) in which the acrolein pr...
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WO/2009/144094A1 |
The invention relates to a method for producing α,ß-unsaturated dicarboxylic acids and the corresponding saturated dicarboxylic acids, whereby the corresponding cycloalkene and acrylic acid are reacted with a ruthenium catalyst by way ...
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WO/2009/144089A1 |
The invention relates to a method for producing 1,2-dodeca-2,10-diene diacid and 1,12-dodecanoic acid whereby cyclooctene and acrylic acid are reacted with a ruthenium catalyst by way of a metathesis reaction at high substrate concentrat...
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WO/2009/145323A1 |
Disclosed is a novel method for oxidizing an alcohol compound. The method for oxidizing an alcohol compound, which is expressed by scheme (1), is characterized by using oxygen in the presence of a polycyclic compound and a nitrous acid c...
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WO/2009/141641A1 |
A production process for the manufacture of ethylenically unsaturated acids or esters thereof is described. The process includes the steps of reaction of an alkanoic acid, or ester of an alkanoic acid, of the formula R3-CH2- COOR4 where ...
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WO/2009/143423A1 |
The present invention provides a novel fumarate compound of aliskiren monofiimarate, and process for preparation thereof. The present invention also provides pharmaceutical compositions comprising aliskiren monofumarate, and methods of u...
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WO/2009/136537A1 |
A process for converting glycerin into an effective chemical raw material. A catalyst for producing acrolein and acrylic acid through glycerin dehydration that can produce acrolein and acrylic acid at a high yield. A glycerin dehydration...
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WO/2009/135977A1 |
The invention relates to a method for obtaining oreganic acid and derivatives thereof, to the intermediate compounds of this synthesis and to the use of said compounds in the preparation of oreganic acid and derivatives thereof.
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WO/2009/133813A1 |
Disclosed is a process for producing acrylic acid, comprising, for example, a catalytic gas-phase oxidation reaction step, a condensation step, a collection step, a distillation step, a crystallization step, and an acrylic acid recovery ...
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WO/2009/133042A2 |
A method is disclosed for transferring heat to a liquid F containing dissolved monomeric acrylic acid, acrylic acid oligomers obtained by Michael addition, and acrylic acid polymer with the help of an indirect heat exchanger to which the...
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WO/2009/134856A2 |
The present invention provides novel pharmaceutical gallium compositions, as well as methods for their preparation and methods for treating conditions and diseases such as cancer, hypercalcemia, osteoporosis, osteopenia, Paget's disease,...
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WO/2009/129701A1 |
The present invention relates to the preparation method of chiral carboxylic acid, especially the asymmetric catalytic hydrogenation reaction for α,β,γ-trisubstituted unsaturated carboxylic acid, when the catalyst is the iridium compl...
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WO/2009/125658A1 |
A process for either producing acrolein and/or acrylic acid on an industrial scale by catalytic gas-phase oxidation of propylene or a propylene-containing gas with molecular oxygen or a gas containing molecular oxygen or producing acryli...
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WO/2009/123151A1 |
In a plate type reactor, there are provided a technique for preventing the runaway of a reaction in the manufacture of a reaction product and for manufacturing the reaction product in a high productivity, a technique for filling the clea...
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WO/2009/122303A2 |
Provided herein is a novel raantlelate sail of fesoterodine, process for the preparation, pharmaceutics!! compositions, and method of treating thereof. Provided also herein are solid state forms of fesoterodine mandelate, process for the...
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WO/2009/123872A1 |
The startup procedure for a process of producing (meth)acrylic acid is described. The procedure includes providing a gas reaction and purification apparatus in a shutdown state. The apparatus includes a reactor and dehydration and finish...
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WO/2009/115350A1 |
The present invention relates to a method for purifying methacrylic acid, wherein the reaction mixture, which is obtained by reacting methacrylamide with water, is cooled by mixing with an aqueous medium and subsequently conducted into a...
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WO/2009/115349A1 |
The present invention relates to a method for producing methacrylic acid by reacting methacrylamide with water, wherein said reaction is performed continuously in a tube reactor and a pressure differential exists in the flow direction of...
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