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Matches 251 - 300 out of 1,815

Document Document Title
WO/2005/009963A1
Chelants and macrocyclic metal complexes thereof, methods of preparing the chelants and macrocyclic metal complexes, and radiopharmaceutical compositions comprising the macrocyclic metal complexes are disclosed. Methods of using the macr...  
WO/2005/003126A1
Diarylethene-containing ligands and their coordination compounds are described. The ligands display photochromism with UV excitation, while the coordination compounds display photochromism with both excitation in the UV region and excita...  
WO2004106390A3
This invention relates to a transition metal catalyst compound represented by the formula: LMX2 or (LMX2)2 wherein each M is independently a Group 7 to 11 metal, preferably a Group 7, 8, 9 or 10 metal; each L is, independently, a trident...  
WO2004026454A3
One aspect of the present invention relates to methods of preparing enedialkylidyne complexes, enediynes, and alkyne metathesis catalysts, as well as methods of catalyzing alkyne metathesis reactions. The present invention also relates t...  
WO2004043380A3
The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates the metho...  
WO/2004/106390A2
This invention relates to a transition metal catalyst compound represented by the formula: LMX2 or (LMX2)2 wherein each M is independently a Group 7 to 11 metal, preferably a Group 7, 8, 9 or 10 metal; each L is, independently, a trident...  
WO/2004/106939A2
The present invention relates to a method for radioactive labeling of a protein or peptide, by providing a protein or peptide having at least one glutamine or lysine residue; adding a metal chelating agent having at least one lysine or g...  
WO/2004/096120A2
This invention provides new small-molecules capable of selective binding to membranes comprising and exposing phosphatidylserine on their surface and / or membranes which have increased amounts of phosphatidylethanolamine in their outer ...  
WO2004044227A3
The invention provides, in a general sense, a new labeling strategy employing compounds that are are N2S2 chelates conjugated to a targeting ligand, wherein the targeting ligand is a disease cell cycle targeting compound, a tumor angioge...  
WO2004050031A3  
WO/2004/092184A1
The aim of the invention is to propose substances, which after introduction into the body are mechanically stable vis-à-vis the chelate and are absorbed by the myocardium, and a method for producing said substances. Technetium-labelled ...  
WO/2004/085497A2
This invention relates to transition metal catalyst compounds represented by the formula: LMX2 wherein M is a Group 7 to 11 metal, L is a tridentate or tetradentate neutrally charged ligand that is bonded to M by three or four nitrogen a...  
WO2004032975A3
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compound...  
WO/2004/076469A1
A method for the synthesis of methyltrioxorhenium is described, wherein 0.5-1.5 moles of dirhenium heptaoxide are reacted with 1-3 moles of tetramethyl tin in the presence of 1-3 moles of chlorotrimethyl silane. The synthesis is carried ...  
WO2003077727A3
One aspect of the invention relates to novel complexes of technetium (Tc) with various heteroaromatic ligands, e.g., pyridyl and imidazolyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeut...  
WO/2004/064536A1
A process for preparation of stable, liquid solutions of complexes of trace elements and amino acid complexes of L-lysine, glycine, leucine, and serine. The resulting complexes are used to supplement domestic animals nutritionally. Since...  
WO2004004635A3
The invention, in one aspect, relates to radiolabeled compounds. The invention also relates to radiolabeled liposomes and methods of making and using thereof. The invention also relates to kits for preparing radiolabeled liposomes.  
WO/2004/052357A1
The present invention is in the field of diagnostic imaging. In one aspect, the invention relates to novel imaging agents comprising synthetic macrophage scavenger receptor A antagonists, said imaging agents being useful in the diagnosti...  
WO/2004/050031A2
Dimetalhydroxy malate compositions as well as methods of administering and making such bioavailable compositions are provided. The metal used can be any nutritionally relevant divalent metal such as calcium, magnesium, zinc, copper, mang...  
WO/2004/043380A2
The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates the metho...  
WO/2004/044227A2
The invention provides, in a general sense, a new labeling strategy employing compounds that are are N2S2 chelates conjugated to a targeting ligand, wherein the targeting ligand is a disease cell cycle targeting compound, a tumor angioge...  
WO/2004/041311A1
The present invention provides radioactive metal heterocomplexes of formula (I): [(Me=N-R) L1L2] +Z- (I), wherein Me, R, L1 L2 and Z- have the meanings indicated in the description. The complexes include a trivalent radioactive metal-imi...  
WO2003099810A3
The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation ...  
WO2004022105A3
The present invention relates to a process for generating a water soluble metal complexed agent, comprising contacting a solid phase bound organic conjugate represented by the formula I with [M(H2O)3(CO)3], under suitable conditions ...  
WO/2004/032975A2
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compound...  
WO2003079737A3
An organic electroluminescent device is described which comprises a compound having a skeleton of the formula (I): which skeleton can comprise one or more additional aromatic rings, wherein each of Z and Z', which may be the same or diff...  
WO/2004/026454A2
One aspect of the present invention relates to methods of preparing enedialkylidyne complexes, enediynes, and alkyne metathesis catalysts, as well as methods of catalyzing alkyne metathesis reactions. The present invention also relates t...  
WO2003093412A3
The invention provides novel amino acid compounds of use in detecting and evaluating brain and body tumors. These compounds combine the advantageous properties of alpha-aminoisobutyric acid (AIB) analogs namely, their rapid uptake and pr...  
WO/2004/022105A2
The present invention relates to a process for generating a water soluble metal complexed agent, comprising contacting a solid phase bound organic conjugate represented by the formula I with [M(H2O)3(CO)3]n+, under suitable conditions to...  
WO/2004/020549A1
Organic EL devices excellent in lifetime, luminous efficiency, color conversion efficiency, and so on, which each contain at least one organometallic complex selected from among (1) organometallic complexes which each comprise a rhenium ...  
WO2002072260A3
A metal bis-triflimde compound having the formula: [Mx][(N(SO2CF3)2)(nx-yz)]<(NX-YZ)-> [Ly] where M is a metal selected from the metals in groups 5 to 10, 12 and 14 to 16 and Cu, Au, Ca, Sr, Ba, Ra, Y, La, Ac, Hf, Rf, Ga, In, Tl, Ce,...  
WO/2004/014927A1
The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to a glutathione peroxidase mimetic. These compounds can be used to treat patients who would benefit from the ...  
WO2003066067A3
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g. rheumatoid arthritis, and of diseases with a strong inflammatory component, suc...  
WO2003101948A3
The present invention provides novel compounds that bind selectively to cells undergoing perturbations and alterations of the normal organization of their plasma membrane, while binding to a lesser degree to cells having membranes of nor...  
WO/2004/007657A1
Use of metal complex compounds of formula (1) [LnMemXp]zYq wherein Me is manganese, titanium, iron, cobalt, nickel or copper, X is a coordinating or bridging radical, n and m are each independently of the other an integer having a value ...  
WO/2004/004635A2
The invention, in one aspect, relates to radiolabeled compounds. The invention also relates to radiolabeled liposomes and methods of making and using thereof. The invention also relates to kits for preparing radiolabeled liposomes.  
WO/2004/000986A1
Transition metal complexes are used as bleaching catalysts for peroxy compounds. Transition metal complexes to be used according to the invention contain a ligand of the general formula (I) wherein B is a bridge member, such as o-phenyle...  
WO/2003/106610A1
Transition metal complexes are used as a bleaching catalyst for peroxy compounds. Transition metal complexes to be used according to the invention contain a polydentate ligand of the general formula (I), wherein B preferably denotes a he...  
WO2003059510A3
Disclosed are manganese(IV) complex salts of formula [LMn(µ-O)3MnL)]n[XM12O40]m, (I), wherein L is 1,4,7-trimethyl-1,4-7-triazacyclononane, X is P or Si, M is Mo or W, n is 2 or 3, and m is 1 or 2, with the provisos that (i) if X is Si,...  
WO2003042135A3
Chiral ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes according to the present invention are useful as catalysts in asymmetric reactions, such as, hydrigenation,...  
WO2002062398A3
The invention provides a complex comprising a) a compound formula (I): wherein R1, X and n have any of the values described in the specification, or a pharmaceutically acceptable salt thereof; and b) a radionuclide. The complexes are use...  
WO/2003/101948A2
The present invention provides novel compounds that bind selectively to cells undergoing perturbations and alterations of the normal organization of their plasma membrane, while binding to a lesser degree to cells having membranes of nor...  
WO/2003/099810A2
The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation ...  
WO/2003/093412A2
The invention provides novel amino acid compounds of use in detecting and evaluating brain and body tumors. These compounds combine the advantageous properties of &agr -aminoisobutyric acid (AIB) analogs namely, their rapid uptake and pr...  
WO/2003/093284A1
According to the invention, a novel type of contrast agent having a superparamagnetic behaviour at ambient temperature is synthesised for use as a contrast agent in magnetic image resonance. The invention relates to the use of a polymeta...  
WO/2003/087209A1
The invention relates to a silicone composition =SiH/=SiOH which can be polymerized/cross-linked by dehydrogenization with condensation in the presence of a catalyst which is suitably selected in order to complete one of the specificatio...  
WO2003049850A3
The invention concerns a method which consists in producing powders with low hygroscopicity by vacuum drying of an aqueous solution, then by grinding, thereby obtaining a compound consisting of crystalline grains, whereof the moisture co...  
WO/2003/084575A1
The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The compounds comprise a metal chelating agent bound to a radionuclide c...  
WO/2003/077727A2
One aspect of the invention relates to novel complexes of technetium (Tc) with various heteroaromatic ligands, e.g., pyridyl and imidazolyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeut...  
WO/2003/079737A2
An organic electroluminescent device is described which comprises a compound having a skeleton of the formula (I): which skeleton can comprise one or more additional aromatic rings, wherein each of Z and Z', which may be the same or diff...  

Matches 251 - 300 out of 1,815