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WO/2015/004457A1 |
A method of mass spectrometry is disclosed comprising transmitting ions and obtaining first mass spectral data and automatically determining during an acquisition whether the first mass spectral data suffers from saturation or is approac...
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WO/2015/003799A1 |
The invention relates to embodiments of high-resolution time-of- flight (TOF) mass spectrometers with special reflectors. The invention provides reflectors with ideal energy and solid angle focusing, based on Cassini ion traps, and propo...
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WO/2015/004459A1 |
A method of mass spectrometry is disclosed comprising digitising a plurality of individual signals or transients and summing the plurality of digitised signals or transients or data relating to the plurality of digitised signals or trans...
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WO/2015/000704A1 |
The invention relates to a determining device for hydrocarbon emissions of a thermal engine, in particular of a motor, having an inspection probe (21), which is designed to remove a sample volume from a liquid, a measurement channel (22)...
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WO/2015/001881A1 |
This mass spectrometric device is provided with a sample container (8) for placing a measurement sample (12) therein, a detector (9) analyzing the mass of a sample and detecting a drug, or the like, contained in the sample, a dielectric ...
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WO/2014/177675A9 |
The present invention provides sample plates for surface enhanced laser desorption ionization (LDI) mass spectrometry having sample surfaces formed from weathering steel. In particular, plates of cut and polished weathering steel sheets ...
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WO/2014/209474A1 |
The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples. Porous materials, such as filter paper or similar materials are used to hold and transfer liquids, and ions are generated...
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WO/2014/210428A1 |
Devices and techniques for ion analysis, including ion mobility separation and mass spectrometry, are provided using a dual polarity spark ion source and having the flexibility required to optimize the detection performance for a broad r...
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WO/2014/207367A1 |
The present invention concerns a system and method of mass spectrometry, comprising the following steps: a. ionising an analyte to form a precursor ion (A) having a mass-to-charge ratio (m/z), in which m represents the mass and z the ato...
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WO/2014/208336A1 |
The mass spectrometric method applies an RF voltage together with an auxiliary alternating voltage, retaining inside an ion trap different species of precursor ions having different mass-charge ratios while ejecting from the ion trap oth...
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WO/2014/203305A1 |
In the interior of an intermediate vacuum chamber (2) in the subsequent stage from an ionization chamber (1) which is an atmospheric pressure environment, an electrode group (20A) of a high-frequency carpet (20) in which a plurality of r...
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WO/2014/201564A1 |
A corona ionization source assembly and fabrication methods are described that include a fine wire including a wire core including a first material, and a wire coating including a second material, where the wire coating surrounds a porti...
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WO/2014/203071A1 |
Methods and systems for performing mass spectrometry are provided herein. In accordance with various aspects of the applicants' teachings, the methods and systems can utilize an ion mobility spectrometer operating at atmospheric or low- ...
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WO/2013/171555A9 |
Systems and methods are provided to perform dead time correction. An observed ion count rate is obtained using a non-paralyzable detection system of a mass spectrometer. The detection system includes an ion detector, a comparator/discrim...
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WO/2014/202892A1 |
The invention concerns a glow discharge mass spectrometry device and method, the device comprising a glow discharge lamp (1), gas flow-injection means, the glow discharge lamp being suitable for forming an ablation plasma in the presence...
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WO/2014/202828A1 |
A device (100) for ionizing sample particles (101a) of a sample gas flow (101), comprises a first flow tube (102) for providing the sample gas flow, and an introducing means (116) for providing H2SO4 molecules (114a) to an interaction re...
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WO/2014/201230A1 |
Examples herein include apparatus and techniques that can be used to perform rotational spectroscopy on gas-phase samples. Such techniques can include using a spectrometer providing frequency synthesis and pulse modulation to provide exc...
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WO/2014/194417A1 |
A mass spectrometer of the type useful in mass cytometry includes an ion detector. A digitizing system for converting analog signals from the ion detector includes two analog-to-digital converters. The analog-to-digital converters are co...
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WO/2014/197341A2 |
Certain embodiments described herein are directed to collision cells that comprise one or more integrated lenses. In some examples, a lens is coupled to two sections of a sectioned quadrature rod assembly, the lens comprising an aperture...
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WO/2014/195783A1 |
Systems and methods are provided for detecting host cell contaminants in a protein biotherapeutic product using sequential windowed acquisition tandem mass spectrometry. Sequential windowed acquisition is performed on a protein biotherap...
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WO/2014/197665A2 |
Integrated nanospray ionization package, comprising a nanospray emitter, a push button carriage with button element projecting through a bore in said package, an integral high voltage contact pin, a bore in said package for reversible pr...
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WO/2014/195677A1 |
A device for manipulating charged particles using an axial electric field as they travel along a longitudinal axis of the device is disclosed. The method comprises providing an outer electrode for generating an electric field and providi...
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WO/2014/197348A2 |
Certain embodiments described herein are directed to rod assemblies such as, for example, quadrupole, hexapole and octupole rod assemblies. In some instances, the rod assemblies include at least one pole comprising an integral fluid path...
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WO/2014/195735A1 |
A method of mass spectrometry is disclosed having a mode comprising: providing a source of precursor ions and reagent ions (2) for reacting with said precursor ions; providing a reaction region (12) downstream of said source(2);providing...
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WO/2014/195785A1 |
Systems and methods are provided for identifying missing product ions after demultiplexing product ion spectra produced by overlapping precursor ion transmission windows in sequential windowed acquisition tandem mass spectrometry. Overla...
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WO/2014/197893A1 |
A diagnostic system and method that includes a non-transitory computer readable medium storing machine executable instructions executable by the processor for altering tissue images, the instructions that further includes an input interf...
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WO/2014/195734A1 |
A method of mass or ion mobility spectrometry is disclosed comprising: providing an ion source for generating analyte ions and reference ions; providing a mass analyser or ion mobility separator (IMS); providing an ion trap between the i...
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WO/2014/191852A1 |
Systems and methods for analyzing a sample comprising an analyte selected from a volatile organic compound, a semi-volatile organic compound, a non-volatile organic compound, a polar organic compound and a halogenated non-volatile organi...
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WO/2014/194172A2 |
Certain embodiments described herein are directed to time of flight tubes comprising a cylindrical tube comprising an inner surface and an outer surface, the cylindrical tube comprising an effective thickness and sized and arranged to co...
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WO/2014/191748A1 |
A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionisation source, a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of the first...
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WO/2014/191821A1 |
A method and apparatus for conducting ion to charged species reactions, more particularly reactions wherein the charged species is an electron, such as ECD. The apparatus comprises first and second pathways which are orthogonal to one an...
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WO/2014/191750A1 |
A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionisation source (701) and a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of ...
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WO/2014/191747A1 |
A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionisation source (701), a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of the...
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WO/2014/194272A2 |
The present disclosure describes devices and methods capable of generating multi¬ phase emulsions, including double emulsion droplets in a gas phase. The present disclosure also describes interfaces for coupling a multi-phase emulsion d...
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WO/2014/191746A1 |
A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionisation source (701), a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of the...
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WO/2014/188251A1 |
Systems and methods are provided for species detection using mass spectrometry. In various embodiments, a multiple reaction monitoring (MRM) experiment is performed on a sample targeting one or more peptide transitions that are unique to...
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WO/2014/185890A1 |
An anti-counterfeit system comprises an item with at least one marker affixed thereto. The marker comprises a chemical signature having at least one chemical, and indicates the source of the item. The marker is detectable in the item to ...
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WO/2014/184570A1 |
A method of manufacturing a device for manipulating charged particles using an axial electric field as they travel along a longitudinal axis of the device is disclosed. The method comprises providing first electrodes of different lengths...
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WO/2014/185214A1 |
The present invention reduces signal pulse detection failures and the deterioration of detection accuracy of the signal pulse area even when the signal pulse output by a photodetector and the timing of A/D conversion are asynchronous. A ...
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WO/2014/181396A1 |
In an SIM measurement, during the pause time for changing the voltage applied to a quadrupole mass filter and other ion transfer optics so as to switch the mass-to-charge ratio of the ions to be measured, the polarity of the direct curre...
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WO/2014/179361A1 |
A method and system for producing an electrospray of desired droplet size and monodispersity. The system comprises a pump for pumping a liquid to a capillary tube. A voltage source is configured for applying a voltage pulse to the tip of...
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WO/2014/177824A1 |
Apparatus (74) for atomising a conducting liquid (88), which apparatus (74) comprises a capillary tube (84), an electric motor (86), means (80) for applying a high voltage, and feed means (94) for feeding the liquid (88) along the capill...
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WO/2014/174048A1 |
An ion trap such as an ion cyclotron resonance analyzer cell (trap) is described wherein the ion trap comprises a plurality of electrodes and comprising at least one integrated ion detector, preferably a position-sensitive and/or time-se...
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WO/2014/175211A1 |
Data obtained by compressing mass spectra at respective measurement points and normalization coefficients for XIC normalization and the like are stored in a memory (21). When an imaging image normalized at a specified m/z value is displa...
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WO/2014/176316A2 |
Method and embodiments are provided for tandem mass spectrometer designed for extremely large charge throughput up to lE+10ion/sec. In one operation mode, the initial ion flow with wide m/z range is time separated in a trap array. The ar...
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WO/2014/169754A1 |
An ion guiding device (3) and method, the ion guiding device (3) comprising: a group of electrode arrays distributed along an axis in space, and a power device providing an asymmetric alternating current field generally along the axis; t...
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WO/2014/169394A1 |
The invention relates to methods and devices for analysis of samples using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The invention provides methods and devices in which individual ablation plumes are distin...
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WO/2014/171378A1 |
Provided is a mass spectroscopy device in which ions and/or particles that were not drawn into an introduction tube or an introduction hole are prevented from diffusing into a chamber. This mass spectroscopy device (1) comprises: an ioni...
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WO/2014/170664A2 |
A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same proper...
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WO/2014/168660A1 |
An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. Th...
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