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WO/2015/153622A1 |
There is proposed a right angle time-of-flight detector (41, 117, 124, 143, 144, 145) comprising a conductive converter (46) for emitting and accelerating secondary electrons, a magnetic field formed by at least one magnet (47) for defle...
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WO/2015/151160A1 |
The present invention provides a mass spectrometry device (1) for measuring in sequence a plurality of subject ions, said mass spectrometry device (1) being characterized by being provided with: a memory unit (41) in which is stored, for...
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WO/2015/153464A1 |
A mass spectrometer system for elemental analysis of a planar sample is provided. In some embodiments, the mass spectrometer system comprises: a primary ion source capable of irradiating a segment on planar sample with a beam of primary ...
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WO/2015/152968A1 |
A method of targeted mass spectrometric analysis is provided for analyzing trace compounds at sub-ppb level compared to the sample matrix. The sample is chromatographically separated at standard conditions to employ a map of target mass ...
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WO/2015/150806A1 |
A method of mass spectrometry or ion mobility spectrometry is disclosed. The method comprises: providing a plurality of species of ions;analysing the ions during a plurality of sequential acquisition periods so as to obtain spectral data...
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WO/2015/150677A1 |
The present invention relates to a system and a process for measuring, by glow discharge spectrometry, the elemental and/or molecular chemical composition of an organic solid sample (10). According to the invention: the sample (10) is po...
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WO/2015/145132A1 |
A detector comprising an analytical apparatus for detecting a substance of interest, and a detector inlet. The detector inlet comprises a flow passage for carrying a flow of fluid, the flow passage comprising a sampling volume,and a samp...
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WO/2015/146614A1 |
Provided is an SIMS analysis method with which contamination of a solid sample to be measured can be prevented, the solid sample can be stably fixed, and good contrast can be exhibited. Further provided is an SIMS analysis device for ana...
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WO/2015/148941A1 |
The invention provides methods, systems and algorithms for identifying high- resolution mass spectra. In some embodiments, an analyte is ionized and analyzed using high-resolution mass spectrometry (MS) at high mass accuracy (such as ≤...
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WO/2015/145124A1 |
A method of charge stripping analyte ions is disclosed. The method comprises reacting the analyte ions with reagent ions or charged particles; and then urging the reacted analyte ions through a neutral, inert gas such that said analyte i...
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WO/2015/145176A1 |
A mass spectrometer is disclosed comprising a gas chromatography separation device, an atmospheric pressure ionisation ion source and a control system arranged and adapted: (i) to operate the atmospheric pressure ionisation ion source at...
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WO/2015/148609A2 |
The present invention provides systems, methods and kits which enable or utilize an immunologically-based assay, such as a Western immunoassay, to separate, detect or to monitor an analyte or a mixture of analytes such as biomolecules.
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WO/2015/148721A1 |
A self-assembled engineered lattice of nanometer-scale silica particles, or other suitable particles generally resembling regularly-sized spheres, is configured in a separation bed for electrophoresis, isoelectric focusing, chromatograph...
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WO/2015/143322A1 |
Systems and methods for a mass spectrometer include an atmospheric-pressure chemical ionization (APCI) source, one or more low-pressure chemical ionization (LPCI) sources, a mass analyzer configured to separate ions of a sample flow from...
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WO/2015/140243A1 |
Sample Slides for Laser Desorption Ionisation (LDI) Mass Spectrometry and Optical Microscopy Indium tin oxide coated slides, their synthesis and use in imaging mass spectrometry are provided in the present application. The methods of syn...
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WO/2015/140491A1 |
A Matrix Assisted Laser Desorption lonisation ("MALDI") ion source is disclosed comprising a first device arranged and adapted to supply a flow of liquid on to the surface of a target or a sample (2) to be analysed so that the liquid for...
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WO/2015/136272A1 |
A method of mass spectrometry is disclosed comprising experimentally determining or measuring 1 one or more first ion mobility values, collision cross sections or interaction cross sections collision cross sections or first ion mobility ...
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WO/2015/136695A1 |
A molecular detection device in one embodiment has an ionization unit, a voltage application unit, a separation unit, and a detection unit. The ionization unit obtains a collection of ionized substances by causing ions to adhere to a col...
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WO/2015/136273A1 |
A method of mass spectrometry is disclosed that comprises predicting 1 one or more first reaction products which may result from subjecting an analyte to one or more reactions of interest, calculating 2 one or more first masses or mass t...
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WO/2015/138826A1 |
Methods of operation of electrostatic ion trap mass spectrometers in which ions are autoresonantly driven at selected higher integer (>2) multiples of ion oscillation frequencies are provided. Excitation at multiples higher than the fund...
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WO/2015/136274A1 |
A method of mass spectrometry is disclosed comprising calculating 3 an ion mobility value, collision cross section or interaction cross section of a plurality of different analyte ions under one or more different analytical conditions, a...
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WO/2015/136266A1 |
A method of separating ions according to a physicochemical property is disclosed. The method comprises causing ions to perform a plurality of cycles along or around an ion guiding path (4) such that the ions separate according to said ph...
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WO/2015/136264A1 |
A method of identifying ions or confirming the identity of ions is disclosed comprising determining a physico-chemical or other property of first ions under first conditions and determining the physico-chemical or other property of the f...
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WO/2015/134190A1 |
A method of validating data produced from a multiplexing process on an analytical instrument is disclosed. In one embodiment, the method includes using a pseudorandom sequence to encode a multiplexed segment of data; applying Hadamard tr...
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WO/2015/133558A1 |
Provided is a projection-type charged particle optical system in which a projection magnification can be changed while a decrease in the accuracy in measuring a mass-to- charge ratio is being suppressed. A projection-type charged particl...
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WO/2015/132579A1 |
A method of mass or ion mobility spectrometry is disclosed that uses the Leidenfrost effect to cause a liquid (2) to be repelled away from a heated surface (4) so as to levitate above there-above. The repelled liquid is urged so as to mo...
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WO/2015/132005A1 |
The invention relates to an ion separating device for a, more particularly miniaturized, mass spectrometer, comprising - a separator channel (3) with accelerator electrodes (2) and preferably an inlet diaphragm (1), - an energy filter (5...
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WO/2015/133259A1 |
In this ion analyzer, ions captured in an ion trap (2) are irradiated with hydrogen radicals introduced at a flow rate of 4×1010 [atoms/s] or more through a radical particle inlet port (26) pierced in a ring electrode (21). Whereby, unp...
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WO/2015/128490A1 |
The inventors have adapted Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) so that it is suitable for single-cell imaging in tissue samples with subcellular resolution. The laser spot size may be 4 μm or less. A ...
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WO/2015/128661A1 |
An ion source is disclosed comprising a nebuliser (1) arranged and adapted to emit a liquid spray, a first target (5) arranged downstream of the nebuliser (1), wherein the liquid spray is arranged to impact upon the first target (5), and...
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WO/2015/128438A1 |
A system for trapping charged or polar particles is provided. The system includes a cryostat and a surface-electrode trap for trapping charged or polar particles. The surface-electrode trap includes a silicon substrate having a front sur...
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WO/2015/126595A1 |
The invention generally relates to systems and methods for analyzing an extracted sample using an immiscible extraction solvent. In certain embodiments, the invention provides a system for analyzing an analyte in a sample. The system inc...
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WO/2015/122586A1 |
The present invention relates to an aerosol mass spectrometer comprising a vaporization-electron ionizer and a laser ionizer which is an aerosol mass spectrometer comprising a source device, a pressure maintaining device, and an ionizati...
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WO/2015/121680A1 |
An apparatus is provided to separate ions temporally according to a physico- chemical property comprising an ion guide comprising a plurality of electrodes and a first device arranged and adapted to remove undesired ions remaining within...
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WO/2015/123555A1 |
The present disclosure provides methods and systems for automated tuning of multimode inductively coupled plasma mass spectrometers (ICP-MS). In certain embodiments, a 'single click' optimization method is provided for a multi-mode ICP-M...
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WO/2015/121366A1 |
The present invention relates to a capillary electrophoresis-mass spectrometer (CE-MS) coupling interface comprising: - a capillary having an inlet section and an outlet section, the outlet section having an outer diameter of between 100...
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WO/2015/123632A1 |
The present invention comprises a method for automated, high throughput molecular identification of macromolecular organic compounds. The method may provide an approximate solution to a momentum transfer cross section of an analyte in a ...
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WO/2015/122920A1 |
The present disclosure provides methods and systems for automated analysis of spectrometry data corresponding to particles of a sample, such as large data sets obtained during single particle mode analysis of an inductively coupled plasm...
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WO/2015/118681A1 |
Provided is a mass spectroscopy device characterized in being provided with: an ionization source having an ESI probe (201), an ESI power source (24), a corona needle (202), and an APCI power source (24); an ionization condition storage ...
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WO/2015/119108A1 |
The present invention enables the high-sensitivity mass spectrometry of a volatile substance in real time under atmospheric pressures. An interface member (1) is connected to a real-time atmospheric pressure mass spectrometer, and the in...
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WO/2015/118321A1 |
A method of mass spectrometry is disclosed comprising monitoring for the emergence of one or more species of ions of interest and determining during the course of acquiring experimental data whether one or more ions or interest have emer...
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WO/2015/120282A1 |
A multiple layer device includes a channel layer having a channel to carry a liquid having particles of multiple sizes, a first electrode layer having a first pair of electrodes disposed about the channel, and a second electrode layer ha...
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WO/2015/110508A1 |
The invention relates to a device (10) for measuring the value of at least one parameter of at least one gas dissolved in a liquid (L), characterised in that it comprises a body (12) and a capturing module (20) mounted on said body (12),...
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WO/2015/111311A1 |
This invention improves the sensitivity of a liquid chromatography-mass spectrometry device by reducing the number of neutral particles that are not ionized during ionization and the number of low-molecular ions from a solvent used in th...
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WO/2015/110507A1 |
The invention relates to a module for capturing at least one gas dissolved in a liquid (L), arranged so as to be mounted on a body (12) of a device (10) for measuring the value of at least one parameter of said gas, said capturing module...
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WO/2015/109105A1 |
A system and method for using a high-performance photoionization subsystem are disclosed. Embodiments of the present disclosure employ narrow bandwidth laser radiation to selectively excite ionizing resonant states of gaseous atoms in el...
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WO/2015/108969A1 |
Mass spectrometry systems include a core featuring an ion source, an ion trap, and an ion detector connected along a gas path, a pressure regulation subsystem connected to the gas path and configured to regulate a gas pressure in the gas...
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WO/2015/107688A1 |
In a dielectric barrier discharge ionization detector (2) according to the present invention, sample components in a sample gas introduced from a sample introduction tube (35) are ionized by the light, and the like, emitted from a plasma...
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WO/2015/104573A1 |
Systems and methods are provided for performing multiplex electrostatic linear ion trap mass spectrometry. A first beam of ions is received and the first beam is split into N beams of ions using a beam splitter. N is two or more. Ions ar...
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WO/2015/101820A1 |
Systems and methods are provided for time-of-flight analysis of a continuous beam of ions by a detector array. A sample is ionized using an ion source to produce a continuous beam of ions. An electric field is applied to the continuous b...
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