Title:
改良されたグルコースデヒドロゲナーゼポリペプチドおよび関連ポリヌクレオチド
Document Type and Number:
Japanese Patent JP2007502114
Kind Code:
A
Abstract:
The present invention is directed to glucose dehydrogenase (GDH) polypeptides that have enhanced GDH activity and/or thermostability relative to the backbone wild-type glucose dehydrogenase polypeptide. In addition, the present invention is directed to a polynucleotide that encodes for the GDH polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the GDH polypeptides, and to a method for producing the GDH polypeptides of the present invention.
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Inventors:
Kleber, Anke
Newman, Lisa Marie
Davis, S. Christopher
Jenne, Stephen Jay.
Newman, Lisa Marie
Davis, S. Christopher
Jenne, Stephen Jay.
Application Number:
JP2006523377A
Publication Date:
February 08, 2007
Filing Date:
August 11, 2004
Export Citation:
Assignee:
Codexis, Inc.
International Classes:
C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N9/04
Domestic Patent References:
| JP2002538782A | 2002-11-19 | |||
| JP2003061682A | 2003-03-04 | |||
| JP2002538782A | 2002-11-19 | |||
| JP2003061682A | 2003-03-04 |
Other References:
JPN6010021853, Ｂｉｏｔｅｃｈｎｏｌ． Ｌｅｔｔ．, 2002, Ｖｏｌ．２４, Ｐ．１２２７−１２３２
JPN6010021855, Ａｐｐｌ． Ｍｉｃｒｏｂｉｏｌ． Ｂｉｏｔｅｃｈｎｏｌ．, 200304, Ｖｏｌ．６１, Ｐ．３２９−３３５
JPN7010001227, Ｊ． Ｆｅｒｍｅｎｔ． Ｂｉｏｅｎｇ．, 1990, Ｖｏｌ．７０， Ｎｏ．６, Ｐ．３６３−３６９
JPN6010021855, Ａｐｐｌ． Ｍｉｃｒｏｂｉｏｌ． Ｂｉｏｔｅｃｈｎｏｌ．, 200304, Ｖｏｌ．６１, Ｐ．３２９−３３５
JPN7010001227, Ｊ． Ｆｅｒｍｅｎｔ． Ｂｉｏｅｎｇ．, 1990, Ｖｏｌ．７０， Ｎｏ．６, Ｐ．３６３−３６９
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita