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JP2019528839A |
Flexible structures according to the exemplary embodiments of the present disclosure include, in particular, a sheath and sutures that are connected to the sheath to form adjustable loops. The suture contains a plurality of spines that a...
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JP6590198B2 |
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JP6581624B2 |
Devices are provided which are functionalized to include surface regions having anti-infective agents. Methods are provided for functionalizing various material surfaces to include active surface regions for binding anti-infective agents...
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JPWO2018079812A1 |
The present invention comprises at least one water-soluble modified hyaluronic acid selected from the group consisting of hyaluronic acid having an anionic modifying group and salts thereof, and from the 3rd to 6th cycles and the 2nd gro...
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JP6576958B2 |
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JP6573886B2 |
Novel absorbable polymeric blends having bimodal molecular weight distribution are disclosed. The bimodal blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide having a bimodal molecular weig...
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JP2019137878A |
To provide a medical device using a magnesium alloy excellent in strength or durability in addition to light weight.The medical device using a magnesium alloy of the present invention, is a medical device using the magnesium alloy, the m...
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JP6563141B2 |
This invention relates to a hyaluronate fiber, and more particularly to a hyaluronate fiber, suitable for use in a surgical suture, a filler for cosmetic surgery, a lifting thread, a tissue-engineering scaffold, etc., and a method of man...
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JP6560507B2 |
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JP2019130384A |
To provide compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use, and kits comprising the compositions.A composition comprises base-treated, detergent-treated telopeptid...
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JP2019111298A |
To provide a surgical suture that facilitates suture, has excellent knotting performance, and achieves a braid structure whose knotted part is small.A surgical suture having a braid structure includes a core yarn at a central part thereo...
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JP2019518785A |
A composition and method for inhibiting and interfering with biofilm formation and destabilizing established biofilms, wherein the composition comprises a polymeric resin and a non-polymerizable and polymerizable monomeric resin. Provide...
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JPWO2018047785A1 |
(a) The following equations (1) ~ (3) H-(X --Y --Gly) n --OH (1) H-(Gly --X --Y) n --OH (2) H-(Y --Gly --X ) n --OH (3) (In equations (1) to (3), X and Y independently represent Hyp or Pro, and n is an integer of 1 to 10). One type of pe...
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JP6529931B2 |
One aspect of the invention relates to a tissue adhesive medical product comprising at least 1% by weight of dry matter of an electrophilically activated polyoxazoline (EL-POX), said EL-POX comprising at least 2 electrophilic groups, inc...
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JP2019084365A |
To provide a medical device adapted to facilitate tissue integration through a tubular wall of a suture.A medical device includes a surgical needle attached to a hollow tubular suture. The suture is constructed of macroporous hollow tubu...
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JP2019513837A |
Anti-infectious disease compositions comprising glycogen or phytoglycogen nanoparticles are provided.
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JP6522134B2 |
An apparatus for forming barbed sutures, the apparatus comprising: a suture frame configured for presenting a plurality of lengths of suture on which barbs are to be formed; a bending mechanism configured to bend the plurality of lengths...
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JP6517443B2 |
This invention relates to a method of manufacturing a hyaluronate-coated high-functional suture and a high-functional suture manufactured thereby, and more particularly to a method of manufacturing a high-functional suture and a high-fun...
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JP2019512479A |
The system includes a support that accepts a nanoparticle assembly (NPA) and is transported towards a local region of an organism that has been infected or is at risk of becoming infected with the nanoparticle aggregate (NPA). A pluralit...
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JP6513782B2 |
Disclosed is a joining element (10), especially a suture material for surgical use. The joining element (10) is composed of a first material (12) that is essentially rigid during impingement by a relatively short-lasting tensile load on ...
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JP2019069263A |
To provide a medical device adapted to facilitate tissue integration through a tubular wall of a suture.A medical device includes a surgical needle attached to a hollow tubular suture. The suture is constructed of macroporous hollow tubu...
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JP2019507662A |
Small diameter suture and suture coating materials made from twists or braids of biocompatible polymer fibers have been developed to support drug delivery and maintain high tensile strength. The fibers take up (eg, encapsulate) one or mo...
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JP6487492B2 |
Provided in one embodiment is a suture, comprising: a porous interior component comprising a volume of pores or interstices, the volume comprising a binding surface; and a first number of biological cells dispersed in the volume; wherein...
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JP2019506365A |
Compounds of formula (I) for use in the prevention or treatment of bacterial infections (in formula, P)XIs selected from the group consisting of (P1), (P2) and (P3)).
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JP2019030671A |
To provide drug delivery platforms which provide for delivery of biologically active agents with a defined profile of release, allowing for potential drawbacks to current strategies for drug release by coated devices.There is provided an...
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JP6470359B2 |
A medical device includes a surgical needle attached to a hollow tubular suture. The suture is constructed of macroporous hollow tubular wall that facilitates and allows tissue integration into the suture core subsequent to introduction ...
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JP6450648B2 |
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JP2018198954A |
To provide an improved medical device.A medical device useful for limiting or suppressing complications (for example, inflammation and restenosis) associated with an improvement of a tissue damage and/or acceleration of tissue repair and...
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JP6425654B2 |
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JP2018533417A |
Copper that is at least partially embedded in at least one filament in a manner in which at least one polymer and at least one copper ion, at least one copper ion, is released over time from at least one filament. A suture containing ion...
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JP6422934B2 |
Disclosed is a joining element (10), especially a suture material for surgical use. The joining element (10) is composed of a first material (12) that is essentially rigid during impingement by a relatively short-lasting tensile load on ...
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JP6396402B2 |
A suture having a first end for penetrating tissue, an elongated suture body having a periphery; a plurality of retainers on the periphery, and a second end having a variable loop of variable circumference, wherein the variable loop incl...
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JP6397190B2 |
An anchorage device comprising a mesh substrate coupled to an implantable medical device is disclosed, where the mesh substrate has a coating comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredi...
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JP2018526434A |
The polymer-drug complex comprises a crosslinked polymer network containing a biocompatible polymer and a polyvalent covalent crosslinker, the polyvalent crosslinker to the biocompatible polymer by two or more bonds. It comprises a coval...
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JP2018526097A |
Auxiliary materials for surgical devices, including agonists and antagonists, are provided. In general, an implantable auxiliary material can have two or more agents arranged so that it can be released internally, and each agent can be r...
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JP2018524132A |
A device that includes a tissue manipulator, a conductive coating and at least one connector section. For example, the tissue manipulator may be scissors, clip appliers or clips, staplers and staples or vascular sealing devices. The cond...
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JP6372000B2 |
The biocompatible cross-linked polymers according to the invention have excellent implant and/or sealing characteristics.
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JP2018114279A |
To provide a medical device comprising a surgery buttress which can be used with a tissue locking device, and a use method thereof.There is provided a medical device which is a buttress containing a porous material comprising a treatment...
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JP6356063B2 |
A self-retaining suture having particular application for treating obstructive sleep apnea and use thereof. The suture includes rising an elongated suture body having a periphery and first and second tissue-penetrating ends each with a b...
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JP2018516648A |
A hemostatic device comprising a surgical fastener and a plurality of fibrinogen-binding peptides immobilized on the fastener. The surgical fastener may be a suture. The device may prevent or reduce bleeding, such as suture hole bleeding...
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JP6342449B2 |
A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug...
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JP6339459B2 |
The present invention provides silk proteins, as well as nucleic acids encoding these proteins. The present invention also provides recombinant cells and/or organisms which synthesize silk proteins. Silk proteins of the invention can be ...
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JP6334635B2 |
The present invention provides threads of hyaluronic acid, and/or derivatives thereof, methods of making thereof and uses thereof, for example, in aesthetic applications ( e.g. , dermal fillers), surgery (sutures), drug delivery, etc.
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JP6328604B2 |
Novel semi-crystalline, segmented copolymers of lactide and epsilon -caprolactone exhibiting long term absorption characteristics are disclosed. The novel polymer compositions are useful for long term absorbable meshes, surgical sutures,...
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JP6329073B2 |
The present invention relates at least in part to methods for the manufacture of shape memory polymer (SMP) materials. Particularly, although not exclusive, the present invention relates to processes for the formation of complex shaped d...
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JP6316589B2 |
A stabilization device for contactless stabilization of a suture thread in a region of the suture thread is disclosed. The stabilization device comprises a source of pressurized fluid and a fluid outlet connected to the source of pressur...
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JP6317258B2 |
The present invention relates to silk proteins which can be used to produce silk with a collagen-like structure, as well as nucleic acids encoding such proteins. The present invention also relates to recombinant cells and/or organisms wh...
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JP6314349B2 |
Provided is an advanced heart failure treatment material, as a myocardial/cardiovascular regeneration device, that self-assembles, which can improve the universality and be used in an emergency by commercialization with no need of cell-c...
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JP6313450B2 |
A method for making an expanded, and optionally multi-component and/or colored PTFE monofilament is disclosed. The method includes forming a first paste by mixing a PTFE powder with a hydrocarbon solvent; forming an extrusion preform by ...
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JP6309967B2 |
The subject matter of the present invention is a bacterium or a mixture of bacteria having an antagonistic activity with respect to strains of S. aureus, P. aeruginosa, Streptococcus pyogenes, Enterococcus faecium, Enterobacter cloacae, ...
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