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JP7102445B2 |
An implantable medical device and method of making it, including a collection of filaments, including a plurality of first variety filaments made of a first polymeric material and at least one second variety filament, and optionally at l...
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JP2022105008A |
To provide means of providing robust biofilm attenuating activity to effectively prevent biofilms or render biofilms susceptible to removal.A polymerizable antimicrobial mixture contains a moiety having formula (I), [R-N+R1R2R3]X- (where...
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JP2022105086A |
To provide a novel antibacterial suture thread which has remarkable antibacterial properties and can be manufactured at rational costs.An antibacterial suture thread includes at least one filament 10, and taurolidine 20 carried by the at...
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JP2022098569A |
To provide a substrate containing conditioned media or exosomes.An inventive substrate can be applied to the surface of a patient's affected area to continuously administer conditioned media or exosomes, facilitating the absorption of th...
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JP7094888B2 |
The present application provies a semi-permeable hydrogel composition comprising an alginate matrix that is covalently crosslinked in its periphery to a multi-armed water soluble polymer, along with related methods and uses thereof.
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JP7089472B2 |
A suture tape construct having a first section formed from a fibrous filament that extends from a first end to a second end and has a pair of a one-way protrusions extending therefrom. An anchor is positioned along the suture construct a...
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JP7076497B2 |
The present invention provides cyclic antimicrobial pseudopeptides that are useful in a variety of applications. Also provided are pharmaceutical compositions, products and kits comprising such cyclic antimicrobial peptides and methods o...
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JP2022526700A |
The present invention comprises an apparatus body (12) preferably containing a material susceptible to corrosion or biodegradation, and a shellac coating (14) in which the apparatus body (12) is at least partially covered by a shellac co...
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JP7072018B2 |
To provide an apparatus for manufacturing a far-infrared radiation product including a suture which can continuously exhibit a sufficient far-infrared radiation effect without damaging a treated object.An apparatus for manufacturing a fa...
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JP7066615B2 |
An antimicrobial suture comprising a filament and taurolidine.
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JP2022524714A |
Biopolymer fiber containing collagen. This biopolymer fiber has excellent extreme tensile strength, modulus of elasticity and elongation at break, comparable to human natural tendons and ligaments. The fibers may be substantially circula...
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JP2022066732A |
To provide a composite thread that is more practical, a method for producing the same, and an uterine cervix treatment device.Provided is a method for producing composite thread that includes a step 1 in which a thread-shaped core materi...
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JP2022523826A |
The polymers and compounding compositions are designed to have properties that can be effectively used in the addition manufacturing process, in particular to create articles in which the molten monofilament polymer is placed on a row of...
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JP2022059088A |
To provide a surgical suture material with a small diameter and a surgical suture coating material.A small diameter surgical suture material and a surgical suture coating material prepared by twisting biocompatible polymer fibers or a br...
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JP7043936B2 |
To provide an antithrombogenic material that can reduce the amount of adsorption of vWF, a coagulation system protein, to the base material surface while letting it have an anticoagulant activity.The present invention provides an antithr...
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JP7036596B2 |
High-consistency nonabsorbable braided suture stock of specified size is prepared from twisted multifilament strands braided together with a tightness of weave of less than 60 picks/inch. The suture stock can be cut to provide sutures, w...
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JP2022042794A |
To provide a metal thin wire for medical use that is a thin wire composed of a bioabsorbable metal but has improved flexibility and strength.A metal thin wire for medical use is composed of two or more wires containing magnesium. The wir...
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JP7027484B2 |
Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
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JP2022032178A |
To provide a bioabsorbable surgical suture that prevents a coating from being peeled off.A bioabsorbable surgical suture has a coating layer on the surface of thread composed of a bioabsorbable material. The thread is monofilament thread...
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JP2022515775A |
The present invention relates to compounds and methods useful for inhibiting the DNA polymerase IIIC enzyme. The invention also provides a pharmaceutically acceptable composition comprising a compound of the invention, and methods of usi...
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JP7023950B2 |
The present invention relates to the use of a shrinkable biopolymer fiber as sensor. In a first embodiment, the sensor allows to determine the authenticity of a product. In a second embodiment, the sensor allows to determine the presence...
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JP2022027694A |
To provide minimally invasive systems and methods for approximating tissues to each other.A minimally invasive surgical method of approximating tissues to each other includes coupling an adjustable loop of a suture around an inserter. Th...
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JP7017726B2 |
Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascula...
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JP7010855B2 |
Methods and devices for the repair of a torn or injured ligament or tendon are provided. The methods include the use of multiple scaffolds, e.g., beads. The multiple scaffolds may be positioned along a suture or other device such that th...
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JP2022509261A |
Disclose new lubricious coatings for medical devices. The coating provides improved lubricity and durability and is easily applied in the coating process at low temperatures that do not deform the tool. The present invention also aims at...
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JP6996556B2 |
An article used in contact with a living body or a biological sample is provided, the article including a first film and a second film, in which the first film includes an amorphous carbon film in which a proportion of the number of carb...
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JP6996793B2 |
A three-dimensional thread making method using ultrasonic waves according to the present invention includes inserting a yarn into a position corresponding to an engraved pattern of a mold base between an ultrasonic wave generator and the...
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JP6995852B2 |
Novel absorbable, semi-crystalline, polymer blend compositions are disclosed exhibiting enhanced crystallization and nucleation rates. Also disclosed are medical device constructs, such as fibers made from such blends. The blends have a ...
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JP6993740B2 |
To provide an easy production technique of filamentous atelocollagen vitrigel having an infinite length and dried product thereof.A method for producing a yarn includes a step of obtaining a filamentous vitrigel in which a first plate-li...
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JP2021192794A |
To provide a hemostatic composite, a method for manufacturing the same, and an application.A hemostatic composite includes a molecular sieve and a fiber, wherein: the molecular sieve distributed on a surface of the fiber and directly con...
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JP6987039B2 |
The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclo...
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JP6986327B2 |
Disclosed is a medical material manufactured using collagen and a method of manufacturing the same. The method includes (1) preparing collagen using distilled water as a solvent, (2) filling a syringe with the prepared collagen and then ...
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JP6972017B2 |
The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectro...
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JP2021178191A |
To provide adjuncts for surgical devices including agonists and antagonists.An implantable adjunct 100 can have two or more medicaments 102, 104 releasably disposed therein that are each releasable from the adjunct. At least one of the m...
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JP6961624B2 |
Provided are a laminated material used for a medical lubricating member, including a base material a, and a layer b which is disposed on the base material a and contains a polymer having a polysiloxane structure, in which the polymer con...
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JP2021526556A |
A composition of mesenchymal stem cell growth factor, and the composition for treating skin disorders, alleviating the effects of aging, treating wounds, orthopedic disorders, sexual dysfunction, and / or reducing inflammation. How to us...
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JP6945370B2 |
A titanium based, ceramic reinforced body formed from an alloy having from about 3 wt. % to about 10 wt. % of zirconium, about 10 wt. % to about 25 wt. % of niobium, from about 0.5 wt. % to about 2 wt. % of silicon, and from about 63 wt....
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JP6940852B2 |
To provide a polyion complex from which a molded body with improved dimensional stability when being contact with a liquid can be formed, and a molded body formed from the polyion complex.There are provided a polyion complex and a molded...
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JP6940203B2 |
The disclosure provides a hemostatic fabric containing trypsin, wherein the hemostatic fabric comprises molecular sieve/fiber composite and trypsin; molecular sieve/fiber composite comprises molecular sieves and a fiber; the molecular si...
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JP2021130711A |
To provide various compounds capable of temporarily hardening soft tissue for surgical suturing of the soft tissue.This invention discloses compounds, such as 7-chloro-4-hydroxy-3-quinolinic carboxylic acid. The compounds according to th...
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JP6933411B2 |
The disclosure provides a hemostatic compound, the hemostatic compound comprises molecular sieves and a fiber, and the molecular sieves are distributed on the fiber surface of the fiber and directly contact the fiber surface. The particl...
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JP6916950B2 |
Disclosed are a surgical suture with a natural antibacterial drug sustained release function and a preparation method therefor. The antibacterial surgical suture with a long-lasting antibacterial performance is prepared by adopting a com...
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JP6913676B2 |
A composition with improved adhesive and sealant properties comprising a) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted o...
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JP6914914B2 |
A staple cartridge is disclosed. The staple cartridge includes a cartridge body, a plurality of staples, and an implantable layer. The implantable layer includes an inner portion, an outer portion positioned at least partially around the...
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JP6906805B2 |
This method for preparing a thread has a step for obtaining a thread-shaped vitrigel by wetting a first sheet-shaped hydrogel dried body or a sheet-shaped vitrigel dried body in a first aqueous solution and twisting the same into a threa...
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JP6896241B2 |
Provided is a medical suture thread which is less likely to remain curled or is easily uncurled from a curled state. The medical suture thread 100 includes a core thread 110 and an outer thread 120. The core thread 110 includes multiple ...
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JP6896240B2 |
Provided is a medical suture thread as a multifilament, which is formed easily bendable and ensuring favorable operability. The medical suture thread 100 includes a core thread 110 and an outer thread 120. The core thread 110 includes mu...
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JP6894498B2 |
The present invention relates to various compounds capable of temporarily hardening soft tissue for surgical suturing of the soft tissue. The compounds according to the present invention can temporarily increase the hardness or tension o...
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JP6896745B2 |
Novel p-dioxanone-rich ABA triblock copolymers of p-dioxanone and epsilon-caprolactone, wherein the "B" block is a copolymer of epsilon-caprolactone and a minor amount of lactone monomer, and absorbable devices for long term medical appl...
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JP6887528B2 |
A method of producing a 3D thread using ultrasonic waves according to the present disclosure includes inserting yarn located between an ultrasonic generator and a mold base adjacent to each other into a location corresponding to an engra...
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