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WO/2007/124622A1 |
The 3D porous layered scaffold for tissue engineering and the preparation thereof. Bioabsorbable polylactic acid, polyglycolic acid and copolymer thereof, polycaprolactone and the like, and chitosan, chondroitin sulfate, collagen, hepari...
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WO/2007/113124A1 |
A new biodegradable polymer composed by poly(D,L)lactic acid (PDLLA) and Vitamin E (α-tocopherol) is disclosedα. This polymer shows a high degree of haemocompatibility compared to the original polymer (PDLLA) and is a good candidate as...
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WO/2007/108775A1 |
A multilayer polyelectrolyte support material is provided that includes a polyelectrolyte layer and a polyelectrolyte-polyethylene glycol layer adjacent to the polyelectrolyte layer. The support material also includes a ligand conjugated...
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WO/2007/105719A1 |
The object is to provide a novel substitute material for heparin, which is excellent in safety and in vivo degradability. Disclosed are: a novel substitute material for heparin, which comprises an enzymatically synthesized α-1,4-glucan ...
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WO/2007/105060A2 |
A drug-coated stent and a method for fabricating the stent are disclosed. The stent has an originally flat pattern and connection points where the sides of the flat pattern are joined. The method includes the steps of a) cutting a stent ...
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WO2007081814A9 |
The present invention relates to a multi-functional pharmaceutical package surface and a method of preparing a multi-functional pharmaceutical package surface. In particular, the present invention relates to a pharmaceutical package havi...
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WO/2007/098484A2 |
Polymer surfaces coated with organometallic layers, wherein the organometallic layers and polymer surfaces have functional groups that react to bond the organometallic layer to the polymer surface with organometallic functional groups re...
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WO/2007/089894A2 |
Alloys of tricalcium phosphate and metal oxide such as TiO2 and SiO2 (ACP) are disclosed as well as method for making these alloys. Method for making these alloys include the steps of milling amorphous tricalcium phosphate and at least o...
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WO/2007/085461A2 |
The present invention relates to a method for the anticoagulation of human blood ex vivo in which blood calcium concentration remains the same, no thrombin is formed and thrombocyte function is not affected. The invention further relates...
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WO/2007/082176A2 |
A method for coating a material on targeted surfaces, such as on an implantable medical device, includes providing a spray application apparatus that defines an application zone within which a spray device is disposed, and supplying the ...
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WO/2007/065359A1 |
A method of preparing a material with blood compatibility comprises dissolving polymer into an organic solvent to form a polymer solution; dissolving an anticoagulant in an inorganic solvent to form an emulsion, slurry or fluid-like mixt...
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WO/2007/067171A2 |
A method, computer program product, and system for receiving a data signal from a transmitting device. The data signal is processed to determine if the data signal is a device data signal or a personal data signal. If the data signal is ...
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WO/2007/062306A2 |
Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. A...
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WO/2007/059038A2 |
A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a roughened surface. The method further comprises the act of de...
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WO/2007/054637A1 |
According to the invention, the hemocompatible material comprises a strong and leaktight synthetic substrate, to which a biological tissue adheres by virtue of the constituent substance of said substrate dispersing in a solvent.
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WO/2007/055761A2 |
Dental dressing assemblies are formed from hydrophilic polymer sponge structures, such as a densified chitosan biomaterial.
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WO/2007/050565A2 |
This invention relates to a method for coating a medical device comprising the steps of applying to at least a portion of the surface of the medical device, a bactericidal coating layer, wherein the bactericidal coating layer comprises a...
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WO/2007/041972A1 |
Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing...
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WO/2007/044339A2 |
An improved process for electrostatically coating a medical device is described. Temporary conductivity is induced into the surface of a medical device whose surface is normally non-conductive. After inducing temporary conductivity to th...
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WO/2007/033282A2 |
A method of depositing shape memory or superelastic thin films by chemical vapor deposition (CVD) and medical devices made thereby, including stents, grafts, stent-grafts, stent covers, occlusive and filter membranes and drug-delivery de...
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WO/2007/030776A2 |
Masses of particles are structurally supported by the application of vacuum through a support surface having holes thereon that are smaller than the average diameter of the particle mass that is to be supported. The reduced pressure stru...
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WO/2007/021620A2 |
Liquid curable perfluoropolyether (PFPE) materials are provided for use as coatings, sealants, flexible fillers, and structural parts for a wide variety of medical applications, particularly where silicone has been utilized conventionall...
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WO/2007/018980A2 |
An ultrasound apparatus and technique produces precise and uniform coatings on various substrates such as stents or other medical devices. The apparatus and technique increases adhesiveness of the surface of the stent or other medical de...
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WO/2007/016251A2 |
Medical devices for implantation within a body vessel comprising a thromboresistant material are provided. The thromboresistant material preferably comprises a biocompatible polyurethane, a remodelable material, a bioactive agent or any ...
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WO/2007/014787A1 |
New triflusal-containing polymeric compounds resulting from the polymerization of 2-(methacryloyloxy)ethyl 2-acetyloxy-4-(trifluoromethyl)benzoate with butyl acrylate are described. These new polymers exhibit good adhesion and crack-brid...
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WO/2007/012282A1 |
A biological artificial blood vessel and the preparation method for producing the blood vessel. The biological artificial blood vessels is composed of a substrate (1) made of an animal blood vessel, and an coating (2) bonding on the inne...
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WO/2007/010201A2 |
A coating for a medical device, the device generally being of the type which is to be used internally in a subject, includes a transglutaminase (TGase) inhibitor. The Tgase inhibitor effectively prevents the activity of any Tgase involve...
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WO/2007/010536A2 |
Conductive surfaces of e.g., implantable devices, coated with electropolymerized polymers having active substances attached thereto are disclosed. Electropolymerizable monomers designed and used for obtaining such conductive surfaces and...
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WO/2007/011385A2 |
A method of curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition...
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WO/2006/133027A2 |
The invention provides methods for immobilizing molecules on metallic surfaces, and compositions containing one or more surfaces that have been treated by these methods. The compositions may be used, e.g., to improve or repair cell, tiss...
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WO/2006/126926A1 |
Disclosed is a coated suture thread comprising a matrix formed by an immobilized and crosslinked plurality of fibrinogen layers into and/or onto which one or several pharmacological substances that inhibit tissue break-down, such as MMP ...
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WO/2006/125086A2 |
A system and method for coating implantable medical devices so that they do not interfere with MR imaging are described. Using any of the coating processes well known to those skilled in the art, e.g., physical vapor deposition such as e...
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WO/2006/121908A2 |
Compositions that include a polymer and an agent impregnated in the polymer are disclosed. In certain examples, the agent is a pharmacological agent that is impregnated in the polymer and may elute from the polymer into fluid, such as bl...
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WO/2006/118757A2 |
A stent, having openings, is mounted onto a mandrel. An agent-containing film is applied onto the stent and the two are pressed against one another so that at least a portion of the film is pressed at least partially into the openings. T...
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WO/2006/109055A2 |
The invention relates to a method of rendering the surface of a substrate, or at least part of the substrate, to have increased protein resistance. This is achieved by applying an n-substituted glyconic derivative onto the surface of the...
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WO/2006/109590A1 |
By coating a base material with a film of a fluoropolymer such as PTFE, the coefficient of friction of the base material is lowered and the slipperiness of the base material is thus improved. Thus, it is intended to provide a medical ins...
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WO/2006/104117A1 |
Disclosed is a modified substrate which is characterized by comprising, as the constitutional component, a polymer having an ester group in the main chain or a side chain and also having a hydrophobic group. Particularly, a polymer havin...
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WO/2006/105126A2 |
The beneficial agent is applied into the holes in a medical device in a dry particulate form and is adhered in the hole in a manner that allows release of the drug in a controlled manner. The drug material would be formed into particles ...
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WO/2006/100895A1 |
An adhesion-preventive film which has excellent flexibility and can be prevented from cracking. The adhesion-preventive film comprises a copolymer of lactide with caprolactone, wherein the lactide/caprolactone copolymer has a lactide/cap...
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WO/2006/094521A1 |
To provide a medical treatment device wherein the antithrombotic property and lubricity of a coating formed on the surface can be maintained in a stable state for a long period and also to provide a method for manufacturing the same. A m...
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WO/2006/093778A2 |
A solid freeform fabrication method of creating a three-dimensional article built at least in part from scaffolding layers, the method includes providing a scaffolding material, providing a supporting material in a shape of a foamy layer...
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WO/2006/081065A2 |
This invention relates to the reduction of interaction of biological systems with foreign substrates. Some applications require that the contact of a biological fluid with a foreign surface, such as a container for that fluid, have minim...
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WO/2006/071649A2 |
An antimicrobial barrier comprising a structure including a chitosan biomaterial. The antimicrobial barrier can be used, e.g., (i) stanch, seal, or stabilize a site of tissue injury, tissue trauma, or tissue access; or (ii) form an anti-...
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WO/2006/068516A1 |
Medical devices comprising a copper antagonist suitable for introduction into a subject, with or without therapeutic agents.
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WO/2006/067959A1 |
It is intended to provide a medical instrument with the use of a composite material which has antithrombotic characteristics and a biocompatibility, has a favorable strength per se and is excellent in handling properties. Namely, a medic...
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WO/2006/055049A1 |
Coatings for an implantable medical device and a method of fabricating thereof are dis-closed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biol...
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WO/2006/055779A2 |
A device for cleaning a cannula of a medical instrument includes an elongated support and a guiding member (12) which has proximal (126) and distal (14) ends. A cleaning element (18) secured to the distal end (14) is formed of a substant...
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WO/2006/050110A2 |
Pro-fibrotic coatings for medical articles are described that include a pro-fibrotic polymer such as collagen. The pro-fibrotic coatings can also include a thromboresistant polymer. The coatings can be formed by activation of photoreacti...
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WO/2006/037080A2 |
A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addit...
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WO/2006/036969A2 |
A barrier layer and corresponding method of making provide anti-inflammatory and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti...
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