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WO/2014/076965A1 |
The present invention provides: an inhibitor of the proliferation of a human-infecting malaria-causing protozoa and a human-infecting protozoa of the genus trypanosome; and a therapeutic agent and a prophylactic agent. Specifically, a ph...
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WO/2014/078372A1 |
Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Ring B, and Ring C are as defined herein, and wherein Ring B moiety and the NH-C...
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WO/2014/078813A1 |
The present invention provides compounds of formula I: [INSERT FORMULA HERE] or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides p...
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WO/2014/078162A1 |
Provided are novel methods and formulations for topically controlling ectoparasite infestations in animals using spinetoram, or a pharmaceutically acceptable salt thereof.
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WO/2014/074778A1 |
The present invention relates to the antimalarial compounds of formula (l)and their use against protozoa of the genus Plasmodium, including drug-resistant Plasmodia strains. This invention further relates to compositions containing such ...
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WO/2014/072903A1 |
The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention als...
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WO/2014/069665A1 |
Provided is a composition for animal parasite extermination comprising as the active ingredient at least one type of 3-aminoxalylaminobenzamide derivative represented by general formula (1). (R1 and R2 are halogen atoms, C1 to C5 haloalk...
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WO/2014/065209A1 |
Provided are: a pyridine compound or a salt thereof that has excellent insecticidal activity and/or acaricidal activity, is highly safe, and can be synthesized industrially advantageously; and a pest control agent including the same as a...
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WO/2014/053691A1 |
The invention relates to bis-pyridinium cyclophane derivatives of general formula I, L being a group of formula II, wherein Q is the conjugated base of an organic or inorganic acid and has a negative charge q; A and B are independently s...
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WO/2014/054421A1 |
The present invention provides a Peyer's patch activator containing polysaccharides obtained from sugar cane as active components. The polysaccharides mainly comprise α-glucans, and have a peak molecular weight in the range of 720,000-1...
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WO/2014/051440A1 |
A method of treating an animal infested with biting lice characterised by the step of administering internally to the animal a pharmaceutically effective amount of spinosyn such that the spinosyn is present systemically within the animal.
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WO/2014/049397A1 |
The invention relates to a synergic pharmaceutical composition of mebendazole (MBDZ) with nitazoxanide (NTZX) for the treatment of human parasitosis, which significantly increases the spectrum of MBDZ against protozoa and reinforces the ...
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WO/2014/044754A1 |
The invention provides novel indazole-substituted diaminopyrimidines of formula I, to methods of preparing such compounds, to pharmaceutical compositions containing such compounds,and to methods for using such compounds in treatment of d...
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WO/2014/044755A1 |
The invention provides novel indole- and benzimidazole-substituted diaminopyrimidines of formula I, to methods of preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods for using such compounds...
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WO/2014/043265A1 |
The present invention relates to methods of decreasing the infectivity, morbidity and rate of mortality, in treating diseases associated with a variety of pathogenic organisms, specifically diseases involving one or more pathogens that r...
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WO/2014/039484A1 |
The invention recites spirocyclic isoxazoline derivatives of Formula (1) stereoisomers thereof, veterinary or pharmaceutical acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an anim...
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WO/2014/039489A1 |
The invention recites spirocyclic derivatives of Formula (V.1) or (V.2), stereoisomers thereof, veterinary acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide for an animal. The variables...
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WO/2014/037592A1 |
A recombinant protein (rHc23) of H. contortus was produced after establishing that the native protein Hc23, with a molecular weight of 23kDa, originating from a soluble extract from the adult haematophagous nematode H. contortus demonstr...
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WO/2014/033597A1 |
The present invention relates to 5-azaindole type compounds responding to the following formula (I): for their use as drugs, and more particularly for the prevention and/or the treatment of diseases and/or disorders chosen amongst cancer...
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WO/2014/034046A1 |
The present invention relates to a vaccine formulation against Toxoplasma gondii infection. More specifically, the invention relates to a vaccine formulation prepared by encapsulating a Toxoplasma gondii-derived soluble protein in a lipo...
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WO/2014/033497A1 |
The present invention relates to 5-azaindole type compounds responding to the following formula (I): for their use as drugs, and more particularly for the prevention and/or the treatment of diseases and/or disorders chosen amongst cancer...
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WO/2014/034750A1 |
The purpose of the present invention is to provide a novel anthelminthic agent or a novel endoparasite control agent such as an antiprotozoal agent. Provided is an endoparasite control agent which contains a carboxamide derivative repres...
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WO/2014/036056A1 |
The present invention relates to novel crystalline modifications of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4
,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofu
ran]-1-yl)-2-(methylsulfonyl)ethanone. The pres...
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WO/2014/036198A1 |
A peptide inhibitor is provided which specifically inhibits the binding of a LACK or TRACK protein to its cognate binding protein. The peptide inhibitor is useful in methods and compositions for protection against infection by Leishmania...
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WO/2014/034751A1 |
The purpose of the present invention is to provide a novel anthelminthic agent or a novel endoparasite control agent such as an antiprotozoal agent. Provided is an endoparasite control agent which contains a carboxamide derivative repres...
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WO/2014/023145A1 |
A mite killing bactericide and a method for preparing same. The mite killing bactericide is prepared by using medicinal alcohol as a main ingredient in combination with herbal medicine such as pure herbal essential oil, natural borneol, ...
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WO/2014/022859A1 |
Compositions and methods for treating parasitic infections are provided. The compositions can include two or more of alpha-pinene, linalyl acetate, para-cymene, and thymol octanoate. The compositions and methods can be effective against,...
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WO/2014/020062A1 |
The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against merozoite surface prot...
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WO/2014/020291A2 |
The present invention concerns a mutant strain of Neospora spp, in which the function of the protein NcMIC3 and/or the function of the protein NcMIC1 is suppressed, and the uses thereof in a pharmaceutical composition or in a vaccine com...
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WO/2014/020218A1 |
The present invention discloses a vaccine against infestations caused by blood-sucking arthropods, preferably ticks, mosquitoes, sand flies, red poultry mites, fleas, lice, sea lice, etc. The invention also claims protection for a peptid...
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WO/2014/020290A2 |
The present invention concerns strains of Sarcocystidae chosen from Toxoplasma spp or Neospora spp isolated from the natural environment of same and having an immunostimulating effect for the use of same in the prevention or treatment, i...
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WO/2014/021468A1 |
A fused heterocyclic compound represented by formula (1) has an excellent pest control effect. (In the formula, R1 represents a C1-C6 chain hydrocarbon group or the like; R2, R3 and R4 may be the same or different, and each represents a ...
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WO/2014/017569A1 |
A pharmaceutical product for lowering blood LDL, which is a pharmaceutical product that contains a compound represented by formula (I) as an active ingredient, said compound having actions of inhibiting the expression of PCSK9mRNA, lower...
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WO/2014/016317A1 |
The present invention relates to the synthesis of GPI-related surface antigens of the parasite Toxoplasma gondii (T. gondii) and the resulting products obtained. These synthetic compounds are suitable for diagnosis of toxoplasmosis, as w...
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WO/2014/010737A1 |
Provided is a novel pest control agent, particularly a fungicide and nematicide. An oxime-substituted amide compound represented by formula (I) [where G1 represents a structure represented by G1-1 or the like; G2 represents a structure r...
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WO/2014/012014A1 |
The invention relates to methods and related products for treatment or protozoan disease. The invention also relates to new compositions of matter useful in the treatment of protozoan disease and methods of identifying additional active ...
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WO/2014/006262A1 |
The invention relates to fragments of peptides homologous with those present in the sequence of arginine kinase that can confer protective immunity in mammals against infection by larvae of dipterous insects that can cause myiasis. The i...
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WO/2014/007395A1 |
Provided is a novel pest control agent, in particular, an insecticide or a miticide. A pyrazole or thiazole derivative represented by formula (1) or a salt thereof. (In the formula, A1 represents -N(O)m2 or -CR1; R1 represents a hydrogen...
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WO/2014/004378A1 |
Anaplasma phagocytophilum surface proteins Asp 14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for vaccines to treat or prevent infections caused by tick-born bacteria of the Anaplas...
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WO/2014/001120A1 |
The present invention provides compounds of formula (I). The invention also provides methods of controlling insects, acarines, nematodes or molluscs using the compounds of formula 1.
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WO/2014/001588A1 |
The invention relate to an antiparasitic composition for controlling and treating parasites of different animal species, characterised in that it combines moxidectin with vitamins: A, D3 and E. This combination offers the wide action spe...
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WO/2013/191188A1 |
This fused heterocyclic compound represented in formula (1) has excellent effectiveness in pest control. (In the formula, A1 represents -NR4-, etc., A2 represents a nitrogen atom, etc., R1 represents an ethyl group, a cyclopropyl group, ...
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WO/2013/191189A1 |
This fused heterocyclic compound represented in formula (1) has excellent pest controlling effectiveness, and is useful as an active ingredient in pest control agents. (In the formula, A1 represents -NR6-, an oxygen atom or a sulphur ato...
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WO/2013/191113A1 |
The fused heterocyclic compound represented by formula (1), or an N-oxide thereof, has excellent effectiveness in pest control. (In the formula, G1 represents a nitrogen atom, etc.; G2 represents a nitrogen atom, etc.; A1 represents a ni...
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WO/2013/190123A1 |
The invention relates to novel pyrimidinone-based heterocyclic compounds which are parasite growth inhibitors, having the general formula (I) in which Y is a morpholine chosen from three bridged morpholines, L is a bond or a linker, n = ...
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WO/2013/190103A1 |
The invention relates to a sialic acid derivative of formula (I), wherein the symbols have the meanings specified in the description, which is suitable for linking to a cargo for regulating metabolic processes, immune reactions, immuniza...
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WO/2013/192035A1 |
Disclosed are solid forms of 1-[(2-chloro-5-thiazolyl)methyl]-3-(3,5-dichlorophenyl)-2-hy
droxy-9-methyl-4-oxo-4H-pyrido[1,2-α]pyrimidinium inner salt (Compound 1). Methods for the preparation of solid forms of Compound 1 and for the co...
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WO/2013/188928A1 |
The invention relates to a dosage regime for treating an animal over a pest season, the dosage regime comprising a first dosage projectile having a unique identifier and containing a first pesticide; a second dosage projectile having a u...
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WO/2013/191112A1 |
The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. (In the formula, J represents formula J1, J2, J3, J4, J5 or J6; A1 represents a nitrogen atom, etc.; A2 represents a nitrogen atom, e...
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WO/2013/182990A1 |
The present invention relates to the preparation of oxyclozanide-based veterinary worming compositions for administration to the skin.
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