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WO/2015/041318A1 |
The invention provides an oligodeoxynucleotide containing humanized K-type CpG oligodeoxynucleotide and polydeoxyadenylic acid, wherein polydeoxyadenylic acid is located on the 3' side of the humanized K-type CpG oligodeoxynucleotide. Th...
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WO/2015/039638A1 |
The invention relates to a new use of diphenyleneiodonium (DPI) as an active substance against parasites of the family Trypanosomatidae, in particular against parasites of the genus Leishmania and Trypanosoma.
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WO/2015/041360A1 |
A tetrazolinone compound represented by formula (1) (where R1 represents a C1-C3 alkyl group or the like; R2, R3, and R4 each represent a hydrogen atom or the like; R5 and R6 each represent a hydrogen atom or the like; and X1 and X2 repr...
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WO/2014/207766A9 |
The present invention disclose a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of benzo fused olefins of formula (II) to obtain library of dioxolo compounds of formula (I). The invention furthe...
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WO/2015/032922A1 |
The present invention relates to a composition for use as an oral anti-parasitic, the composition comprises one or more of an essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucaly...
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WO/2015/032998A1 |
The present invention relates to the field of lymphoproliferative Theileriosis, and more particularly to peptidyl-prolyl cis/trans isomerase 1 (PIN1) inhibitors for their use in the prevention and/or treatment of lymphoproliferative Thei...
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WO/2015/032943A1 |
The invention relates to compounds of Formula (I) and its use as a selective dipeptidyl peptidase I inhibitor, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.
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WO/2015/032945A1 |
The invention relates to compounds of Formula (I) and their use as selective dipeptidyl peptidase I inhibitors, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.
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WO/2015/027959A1 |
The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general for...
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WO/2015/028427A1 |
Disclosed are compounds of formula (I) which possess pesticidal, especially nematicidal properties, wherein the structural elements have the meaning as indicated in the description.
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WO/2015/021534A1 |
A limonoid composition for the prevention and control of marine ectoparasites on fish is provided herein. Said composition comprises at least one limonoid selected from the group consisting of azadirachtin, salannin, meliantriol, karanji...
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WO/2015/016335A1 |
A tetrazolinone compound represented by formula (1) [wherein Q represents a bivalent 5-membered aromatic heterocyclic group which may have at least one atom or group selected from the group P2; A represents a 5- to 10-membered monocyclic...
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WO/2015/016372A1 |
A tetrazolinone compound represented by formula (1) (in the formula, R1 and R2 are the same or different, and represent a hydrogen atom, or the like; R3 represents a C1-C6 alkyl group, or the like; R4, R5 and R6 are the same or different...
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WO/2015/013739A1 |
An immunogenic composition and method of producing an immunogenic composition include isolated or purified blood-stage Babesia parasites, or red blood cells infected with blood-stage Babesia parasites, treated with tafuramycin A or an an...
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WO/2015/010641A1 |
Provided are substituted quinazolin-4-one compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein R1,R2,R3,R5,R6 and L are as defined in the description. Such compounds are suitable for the ...
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WO/2015/008246A1 |
The present invention is related to a use of pyrazole derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to pyrazole derivatives useful for the preparation of...
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WO/2015/007870A1 |
The present invention relates to new compounds for treating, preventing or inhibiting a parasitic disease, preferably toxoplasmosis in a subject, the method for preparing thereof.
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WO/2015/006752A1 |
The present disclosure provides methods for treating or preventing malaria by administration of a protein kinase inhibitor and optionally one or both of a further protein kinase inhibitor and an antimalarial drug to a mammalian subject i...
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WO/2015/002211A1 |
Provided is a fused heterocyclic compound which has excellent control efficacy on pests and is represented by formula (1). (1) (In the formula, A1 is NR5, etc., A2 and A3 are nitrogen atoms, etc., R1 is a C1-6 chain hydrocarbon group, et...
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WO/2015/000929A1 |
The invention relates to compounds characterized by a general formula (1), wherein T is S, SO or SO2, and R is hydrogen or CO-R' wherein R' is unsubstituted or substituted alkyl, alkenyl, alkynyl, aryl, heteroaryl, use in a method for tr...
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WO/2015/001799A1 |
[Problem] To provide a propagation inhibitor, therapeutic agent, and prophylactic agent for Babesia that is infectious to humans and livestock such as Babesia gibsoni, Babesia bovis, Babesia bigemina, Babesia caballi, Babesia (Theileria)...
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WO/2015/002134A1 |
Provided is a novel vaccine that can induce sufficiently high cellular immunity. The vaccine according to the present invention includes a polypeptide containing a tandem repeat structure in which a MHC class I epitope region, which is d...
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WO/2014/208766A1 |
An animal ectoparasite control composition has an excellent controlling effect on animal ectoparasites, said composition containing an organosulfur compound represented by formula (I) and a triester compound represented by formula (A) (f...
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WO/2014/206909A1 |
The present invention relates to thiophene- or furan-substituted isothiazoline compounds of formula I wherein the variables are as defined in the claims and description. The compounds are useful for combating or controlling invertebrate ...
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WO/2014/201914A1 |
A praziquantel-mebendazole nanoemulsion oral liquid medication, the diameter of the droplets thereof being between 10 nm and 100 nm, and the nanoemulsion being made from raw materials in the following percentage by weight: 15.00%-30.00% ...
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WO/2014/200363A1 |
The invention relates to sphingoglycolipid analogues which are useful in treating or preventing diseases and conditions such as those relating to infection, atopic disorders, autoimmune diseases or cancer.
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WO/2014/197703A1 |
Provided are compounds of formula I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as d...
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WO/2014/194503A1 |
Provided are compounds useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described abov...
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WO/2014/193031A1 |
The present invention relates to an antimicrobial agent having a Moringa oleifera extract captured in a porous material and a preparation method therefor and, more particularly, to an antimicrobial agent prepared by capturing a Moringa o...
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WO/2014/192068A1 |
[Problem] Vegetative cells of acanthamoebas are sensitive to drugs and disinfection is relative easy, but since disinfection of acanthamoebas during the cyst period is extremely difficult, the purpose of the present invention is to provi...
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WO/2014/192953A1 |
The tetrazolinone compound according to the present invention, represented by formula (1) (In formula (1), R1 represents a C1-3 alkyl group which may have a fluorine atom, or the like; R2 and R4 represent a hydrogen atom or the like; R3 ...
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WO/2014/188131A1 |
The invention relates to the use of nanoparticles for the production of soluble anti-malarial compositions, pharmaceutical compositions comprising or consisting of these nanoparticles, and a method for producing said nanoparticles.
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WO/2014/184416A1 |
The invention relates to the synthesis and use of compounds comprising squaramide for the treatment of diseases of parasitic origin, such as American trypanosomiasis also known as Chagas disease, or leishmaniasis.
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WO/2014/180011A1 |
An artemether/benflumetol compound fat emulsion injection, a preparation method therefor, and an application of same in preparing medicine for malaria treatment. The fat emulsion contains artemether of 0.01-1.5wt%, benflumetol of 0.01-3....
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WO/2013/057624A9 |
The present invention relates to a method of treating a parasitic infection in an animal, particularly a filarial endoparasitic infection, comprising administering an effective amount of a Formula (I) compound or a Formula (ll) compound ...
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WO/2014/175465A1 |
A tetrazolinone compound shown by formula (1) (in the formula, R1 and R2 each independently represent a hydrogen atom or the like; R3 represents a C1-C6 alkyl group or the like; R4, R5, and R6 each independently represent a hydrogen atom...
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WO/2014/171116A1 |
The present invention relates to a vaccine preparation against malarial parasite infection. More specifically, the invention relates to a vaccine preparation containing a liposome preparation in which a soluble protein derived from a mal...
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WO/2014/169092A1 |
The present invention is directed to stabilized compositions comprising at least one macrocyclic lactone, or derivative thereof, in combination with levamisole, and an amino sugar stabilizing agent, optionally an additional antiparasitic...
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WO/2014/160381A1 |
Compositions and methods are provided for treating or preventing a parasitic disease in a subject. Aspects of the methods include administering an ALDH antagonist to a subject that is infected with a parasite or that is at risk for being...
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WO/2014/153590A1 |
The invention relates to nucleic acid molecules comprising a double-stranded region complementary to a target gene in Neoparamoeba species and methods of reducing the expression of the target genes. The invention further relates to metho...
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WO/2014/154847A1 |
The present invention generally relates to the fields of parasitology and immunology, and especially to a vaccine against Rhipicephalus ticks. In particular the invention relates to a composition comprising a first and a second protein, ...
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WO/2014/157600A1 |
The development of novel agricultural and horticultural pesticides is desired because of factors such as ongoing large damage due to pests and the like in agriculture, horticulture, and other such crop production, the emergence of pests ...
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WO/2014/151729A1 |
The present invention provides compounds of Formula (A) or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical composi...
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WO/2014/147581A1 |
This invention relates to an antimicrobial and antihelminthic agent comprising a compound of formula (I), to a process for extracting the antimicrobial and/or antihelminthic agent from plant material, to a composition containing the anti...
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WO/2014/151784A1 |
The present invention provides compounds of formula (I): (Formula (I)) or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmac...
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WO/2014/148451A1 |
The development of a novel agricultural and horticultural pesticide is desirable as a result of the occurrence of pests that are resistant to existing pesticides and cause increasing damage to agricultural and horticultural crop producti...
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WO/2014/141177A1 |
The present invention relates to new arylaminoalcohol derivatives of formula (I), and to a method for the preparation of such compounds: I The invention also relates to the use of these compounds as medicaments, and in particular for the...
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WO/2014/145037A1 |
The present invention includes methods and compositions to enhance, inter alia, wound repair by administration of 2,3-biphosphoglycerate, myo-inositol trispyrophosphate, or a functional variant thereof.
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WO/2014/142292A1 |
Given that damage caused by pests is still significant in agricultural and horticultural crop production, and the like, the present invention addresses the problem of developing and providing a novel agricultural and horticultural insect...
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WO/2014/142113A1 |
A silica preparation containing cashew nut shell oil, anacardic acid, cardol, or cardanol, and silica particles; the silica particles adsorbing the cashew nut shell oil, anacardic acid, cardol, or cardanol; and the silica particles havin...
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