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WO/2015/133280A1 |
The present invention addresses the problem of providing a novel compound effective against malaria, and an application for the same. Provided is an asymmetrical compound group synthesized on the basis of a molecular design aimed at inte...
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WO/2015/133511A1 |
Provided is an endoparasite control agent that includes, as an active ingredient, a carboxamide derivative represented by general formula (I) or salts thereof in order to provide a novel endoparasite control agent such as an insecticide ...
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WO/2015/133512A1 |
Provided is an endoparasite control agent that includes, as an active ingredient, a heterocyclic carboxamide derivative represented by general formula (I) or salts thereof in order to provide a novel endoparasite control agent such as an...
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WO/2015/131231A1 |
A method for preventing, treating and/or reversing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (-)-perhexiline or a pharmaceutically acceptable salt, prodrug or de...
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WO/2015/127537A1 |
The present document describes a powder composition comprising a functionalized starch having a single helix V-structure and having a degree of substitution of at least 0.25, and a bioactive agent, forming an inclusion complex with said ...
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WO/2015/127548A1 |
The invention encompasses the novel class of compounds represented by the Formula (I) below, which are inhibitors of the TC-PTP enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above an...
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WO/2015/125858A1 |
The present invention is a compound represented in formula (I-1) and the like, or a salt thereof. A harmful organism control agent and the like are obtained that contain at least one selected from the group consisting of the aforemention...
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WO/2015/125824A1 |
Provided is a novel noxious organism control agent, particularly a bactericidal agent and a nematicidal agent. An alkynylpyridine-substituted amide compound represented by formula (I), an N-oxide of the compound, or a salt of the compoun...
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WO/2015/125978A1 |
The present invention aims to provide a more economical and effective nutrition composition that suppresses the growth of hemocytozoon such as malaria parasite and the like. The present invention relates to a nutrition composition for su...
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WO/2015/124120A1 |
Methods of treating autophagy related diseases, e. g. cancer and malaria, using novel autophagy inhibiting agents are described.
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WO/2015/123595A1 |
Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine r...
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WO/2015/118969A1 |
The purpose of the present invention is provide: a novel pyrazole compound; an N-oxide or salt of the compound; methods respectively for producing the compound and the N-oxide or salt; and an agricultural or horticultural drug containing...
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WO/2015/105905A1 |
Provided are methods for treating parasite-mediated inflammation (e.g., demodicosis, stomatitis, dermatophytosis, etc.), comprising administration to a mammalian subject in need thereof a therapeutically effective amount of a heat-treate...
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WO/2015/105198A1 |
The present invention provides anti-trypanosomal, anti-leishmanial or anti-plastmodial agent for treating, preventing trypanosomiasis, leishmaniasis or malaria, respectively, of mammals, which comprises a compound having the tetracyclic ...
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WO/2015/105184A1 |
The objective of the present invention is to prevent and/or treat malaria with an anti-malarial agent comprising, as an active ingredient, a metal chelator such as Tris(2-pyridylmethyl)amine represented by formula (I), (III), (IV), (V), ...
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WO/2015/101918A1 |
The present invention relates to pharmaceutical compositions containing fullerenes, preferably fullerol, which are spherical carbon nanostructures, as novel tools for the treatment of visceral and cutaneous leishmaniasis. The antileishma...
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WO/2015/097139A1 |
The present invention relates to veterinary compositions based on isometamidium and to uses thereof in a long-term curative and/or preventive treatment of trypanosomiasis in non-human mammals. It relates more specifically to a compositio...
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WO/2015/095483A1 |
A tapeworm is suitably modified to reduce side effects and complications when ingested by a host. The tapeworm characteristics are modified so that such modified tapeworm is useful for treating human diseases, such as weight loss, treatm...
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WO/2015/089638A1 |
The disclosure provides a process of obtaining a simplified flax extract by water extraction followed by mechanical extraction. The disclosure further provides compositions comprising the flax extract produced by the process and methods ...
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WO/2015/091898A1 |
This invention is directed to a pharmaceutical composition for drinking water administration comprising isoxazoline compounds of formula (I) and a polysorbate surfactant and diethylene glycol monoethyl ether (transcutol); and the use of ...
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WO/2015/095477A1 |
The present invention provides compounds of Formula A: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical composit...
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WO/2015/090591A1 |
The invention relates to a pharmaceutical composition intended for use in the prevention and/or treatment of leukaemia in a subject, said composition comprising palytoxin (PLTX) and a pharmaceutically acceptable carrier. The application ...
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WO/2015/093558A1 |
Provided are a compound represented by formula (1) or a stereoisomer thereof as a novel cyclic depsipeptide derivative, and a pest control agent which includes the novel depsipeptide derivative.
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WO/2015/085387A1 |
The invention describes the use of compounds produced from root, stem, bark and leaf extracts of plant species of the genus Arrabidaea, in particular Arrabidaea brachypoda, also known in Brazil under the names "cipó-una" and "cervejinha...
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WO/2015/088038A1 |
An aromatic compound expressed by formula (1) exhibits superior pest control efficacy (in the formula: R1 and R2 each independently represent a halogen atom, a C1-C4 alkyl group, or a C1-C4 haloalkyl group, etc.; m and n each independent...
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WO/2015/085860A1 |
Disclosed are a heterocyclic hydroxamic acid compound having a general formula I, and pharmaceutically acceptable acid or alkali salts or stereoisomers thereof. The present compound and pharmaceutically acceptable salts thereof effective...
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WO/2015/085140A1 |
This disclosure provides antibodies that are useful for preventing and/or treating malaria. The epitope to which the antibodies bind is in close proximity to the conserved proteolytic cleavage site of P. falciparum circumsporozoite prote...
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WO/2015/081401A1 |
The present invention relates to an injectable anthelmintic composition of avermectin and basic albendazole sulfoxide for combatting parasites that infest animals. The invention further contemplates a specific method that allows the stab...
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WO/2015/077855A1 |
The present invention relates to a method for selecting tick antigens, comprising the following steps: producing a tick transcriptome; synthetising the proteins; selecting the antigenic proteins; assessing the biological importance of th...
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WO/2015/076422A1 |
Provided is a vaccinia virus that specifically grows in cancer cells and destroys the cancer cells. Also provided is utilization of said virus in cancer treatment. A mitogen-activated protein kinase-dependent vaccinia virus that lacks a ...
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WO/2015/073836A1 |
Methods for treating or prophylaxis of a Cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for alleviating the symptoms of, for treating, or for p...
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WO/2015/070306A1 |
The present invention provides a method for preparing a nanohybrid material, a pharmaceutical composition comprising said nanohybrid material and the uses of said material. In specific, the nanohybrid material is used to prepare a pharma...
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WO/2015/068719A1 |
A pesticide having excellent insecticidal activity and/or acaricidal activity comprises as an active ingredient a compound represented by formula (I) or a salt thereof, and at least one selected from the group consisting of the compound ...
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WO/2015/067648A1 |
The invention relates inter alia to novel compounds of general formula (I), in which the groups A1-A4, T, W, Q, R1 and B1-B4 are defined as cited in the description. Further disclosed are methods for producing the compounds of formula (I...
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WO/2015/067193A1 |
The present invention belongs to the technical field of medicine, and relates to a triazine compound for combating coccidiosis in chickens, a method of preparing said compound, and a use of said compound, the structure of the compound be...
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WO/2015/064725A1 |
Provided is a pyrazole compound represented by formula (1) (1) [In the formula, R is a cyclohexyl group, 3-cyclohexene-1-yl group or 4-methylcyclohexyl group.] which has excellent pest control activity. Also provided is a pesticide which...
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WO/2015/066277A1 |
The present invention relates to novel and inventive isoxazoline of formula (I) and salts thereof: wherein wherein variables D1, D2, D3, D4, D5, R1, B1, B2, B3, R2, R3, R4, R5, R6, Y, Z, L, a and b are described herein are as defined in ...
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WO/2015/064680A1 |
Jelly formulations are problematic in that although a jelly formulation having good fluidity is obtained by increasing the water content, an increase in the water content leads to deterioration of drug stability and poor long-term shelf ...
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WO/2015/064727A1 |
The tetrazolinone compound of the present invention, represented by formula (1) [In the formula, R1 represents a C1-6 alkyl group or the like; R2, R3, and R4 are the same or different and represent hydrogen atoms or the like; R5 represen...
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WO/2015/063544A1 |
The present invention discloses novel substituted 2-aminoquinazolin-4(3H)-one derivatives and their use as inhibitors of malarial aspartic protease plasmepsin I,II,IV or related malarial aspartic proteases, as well as pharmaceutical comp...
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WO/2015/060461A1 |
A tetrazolinone compound represented by formula (1) (1) [In the formula, R1 and R2 are each a hydrogen atom, halogen atom, C1-C3 alkyl group, etc., R3 is a C1-C3 alkyl group which may have one or more halogen atoms, etc., R4, R5 and R6 a...
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WO/2015/056768A1 |
Provided is a new antiparasitic agent for medicinal use, veterinary use, agrochemical use, and use in fish, said antiparasitic agent having an effect on both helminths and protozoa. The antiparasitic agent uses at least one of siccanin p...
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WO/2015/054764A1 |
The present invention pertains to the fields of biotechnology and genetic engineering, in particular to the expression of recombinant peptides. Innoculation of bovines with these peptides produces an immune response capable of destroying...
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WO/2015/055126A1 |
The present invention relates to crystalline levopraziquantel, and preparation method and application thereof. The X-ray diffraction pattern (CuKα radiation) of crystalline levopraziquantel at 25oC shows the following diffraction peaks:...
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WO/2015/051422A1 |
The present invention relates to a class of novel pradimicins and analogues and derivatives thereof, including the compounds of formula A, I and 111, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof ...
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WO/2015/053636A1 |
The invention relates to methods and formulations for veterinary treatment. In particular, the invention relates to methods and formulations for improving the treatment of pathogenic and/or resistant worm strains in an animal by administ...
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WO/2015/046480A1 |
A tetrazolinone compound represented by formula (1) (In the formula: Q is (In the formula, R21, R22, R23, R24, and R27 are a hydrogen atom, etc.), etc.; R1 and R2 are each a hydrogen atom, etc.; R3 is a C1 to C6 alkyl group, etc. which m...
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WO/2015/044348A1 |
The invention relates to compounds from the class of pyranones, used in the prevention and/or treatment of coccidiosis (infection by Eimeria spp.). These compounds are also useful in the prevention and/or treatment of cryptosporidiosis (...
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WO/2015/041722A1 |
The present invention describes a method of treating individuals suffering from microbial infections, including a parasitic disease such as malaria, by using an improved Artemisinin Combination Therapy (ACT), known as ActRx Tri-ACT Plus....
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WO/2015/039199A1 |
The present invention describes methods for preparing micro- and nano-scale polymeric pharmaceutical forms encapsulating benznidazole for parenteral administration, and pharmaceutical forms for oral administration, which self-emulsify in...
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