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WO/2000/017179A1 |
A process for the manufacture of glycidylesters of branched monocarboxylic acids, comprising (a) the reaction of the $g(a)-branched monocarboxylic acid with a halo substituted monoepoxide such as an epihalohydrin (e.g. epichlorohydrin), ...
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WO/2000/017178A1 |
The selectivity of an olefin epoxidation process catalyzed by a titanium-containing zeolite is improved by performing the epoxidation in the presence of a non-ionic tertiary amine or tertiary amine oxide additive. For example, when hydro...
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WO/2000/017177A1 |
The invention relates to a method for optimizing the specific energy consumption of a method for producing ethylene oxide by direct oxidization of ethylene with air or oxygen, using water as the heat transfer medium for removing the heat...
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WO/2000/015334A1 |
This invention relates to a process for depositing one or more catalytically reactive metals on a carrier, said process comprising selecting a carrier and depositing a catalytically effective amount of one or more catalytically reactive ...
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WO/2000/015332A1 |
A method for restoring lost activity and selectivity of fresh cesium-promoted catalysts which comprises heating the catalyst at an elevated temperature in the presence of a sweep gas immediately prior to using the catalyst. The catalysts...
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WO/2000/015335A1 |
There is provided a catalyst carrier comprising a refractory inorganic material having a sodium solubilization rate no greater than 5 ppmw/5 minutes. There is further a catalyst comprising a refractory inorganic material carrier having a...
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WO/2000/012483A1 |
Compounds useful in immunosuppressive and anti-inflammatory treatment are described. The compounds are hydrolyzable triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.
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WO/2000/012432A1 |
The invention relates to a method for producing a titanium silicate with RUT structure, which consists of the following steps: (i) preparation of a mixture of at least one SiO¿2? source and at least one titanium source; and (ii) crystal...
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WO/2000/010986A1 |
A process for the preparation of (2R, 3S)-3-amino-4-phenylbutane-1,2-epoxide, which comprises treating a (2S, 3S)-3-amino-1-halo-2-hydroxy-4-phenylbutane or (2S, 3S)-3-amino-4-phenylbutane-1,2-epoxide either with a quaternary ammonium ca...
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WO/2000/010987A1 |
An aqueous solution of 2,3-Epoxypropyltrimethylammonium chloride having reduced color and method of preparation are disclosed. 2,3-Epoxypropyltrimethylammonium chloride is treated with sodium hypochlorite to reduce its color. 2-3-Epoxypr...
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WO/2000/010985A1 |
The invention relates to a chiral sulphide catalyst, having the structure of formula (IIa) or (IIb) or (IIc) or (IId), wherein X represents a hydrogen atom, alkyl, alkoxy, aryl or alkylaryl group, or a dialkyl nitrogen; Y is a side chain...
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WO/2000/009463A1 |
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile, selected from the group consisting of water, alcohols, carboxylic acids, and thiols, an...
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WO/2000/007964A1 |
The invention relates to a method for oxidizing hydrocarbons on a catalyst which contains silver and titanium and in the presence of a hydrogen-oxygen mixture. Said catalyst contains a) a supporting material which contains titanium and b...
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WO/2000/007965A1 |
The invention relates to a method for reacting an organic compound with a hydroperoxide, comprising at least the following steps (i) to (iii): (i) reacting the hydroperoxide with the organic compound to obtain a mixture composed of a rea...
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WO/2000/005226A1 |
This invention provides an improved gas phase feed process using heterogeneous catalysis for the selective epoxidation of non-allylic olefins wherein the epoxidation is carried out in the presence of branched-chain alkane or cyclic aliph...
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WO/2000/005186A1 |
Process for the joint preparation of styrene and propylene oxide comprising the steps of: (a) reacting ethene and benzene to form ethylbenzene; (b) reacting ethylbenzene with oxygen or air to form ethylbenzene hydroperoxide; (c) reacting...
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WO/2000/005227A1 |
This invention relates to a process for manufacturing an optically active (S)-3,4-epoxybutyric acid salt and more particularly, to a method for manufactuing (S)-3,4-epoxybutyric acid salt expressed by formula (1), wherein an optically ac...
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WO/2000/004865A2 |
Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.
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WO/2000/002839A1 |
A compound of formula (I), wherein $g(a)X is =O, =N-OR?6¿, $g(b)NHR or $g(b)OH wherein R?6¿ is H or C¿1?-C¿6? alkyl, bond a is oriented $g(g) or $g(d) and R is H, C¿1?-C¿6? alkyl which is unsubstituted or substituted by C¿6?-C¿10...
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WO/2000/001650A1 |
The invention provides a method of producing $g(a)-tocopherol and $g(a)-tocopheryl esters and a method of producing vitamin A or $g(b)-carotene. The methods comprise using a biological system to produce farnesol or geranylgeraniol. Then,...
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WO/2000/001649A1 |
The invention provides a method of producing $g(a)-tocopherol and $g(a)-tocopheryl esters. The method comprises using a biological system to produce farnesol or geranylgeraniol. Then, the farnesol or geranylgeraniol is chemically convert...
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WO/2000/001685A1 |
The invention provides methods for producing tocopherol compounds of the Vitamin E family by reduction of various 4-chromanone trienol materials. In preferred embodiments the invention provides methods of preparing and hydrogenating 4-ch...
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WO/2000/001686A1 |
The invention provides processes for producing phytol, isophytol, and certain phytol derivatives by a method of oxidizing or epoxidizing geranylgeraniol or geranylgeraniol derivatives to form epoxygeranylgeraniol derivatives, reducing or...
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WO/1999/067252A2 |
The invention relates to epothilone analog represented by formula (I) wherein (i) R¿2? is absent or oxygen; 'a' can be either a single or double bond; 'b' can be either absent or a single bond; and 'c' can be either absent or a single b...
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WO/1999/065895A1 |
The invention relates to compounds of formula (Ia), wherein R¿1a? represents hydrogen, an -S(O)¿Z?-(C¿1?-C¿4?)Alk group, a -CO(C¿1?-C¿4?)Alk group, an -NHSO¿2?-(C¿1?-C¿4?)Alk, an NHCO(C¿1?-C¿4?)Alk group, a 2-furyl group or a ...
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WO/1999/064393A1 |
The invention relates to novel antiestrogens of general formula (I), wherein the substituents which have the meanings cited in the description. The novel compounds concern a) pure antiestrogens or b) antiestrogens having a partial estrog...
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WO/1999/062894A2 |
A process for making an aromatic glycidyl ether epoxy compound by contacting an allyl ether made from the hydroxy moiety of a hydroxy-containing aromatic compound with an inorganic or organic hydroperoxide oxidant in the presence of a tr...
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WO/1999/062867A1 |
Cardiac failure remedies containing as the active ingredient indan derivatives represented by general formula (I) or medicinally acceptable salts thereof, wherein R?1¿ is hydrogen, nitro, cyano, amino, C¿1?-C¿6? alkylcarbonylamino or ...
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WO/1999/061432A1 |
The present invention relates to angiogenesis-inhibiting compounds represented by formula (I) wherein R¿1? through R¿5? are as defined herein. Compounds of the invention are analogs of fumagillin and are useful in therapy and prophylax...
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WO/1999/059986A1 |
The present invention relates to a fumagillol derivative represented by chemical formula (1) or pharmaceutically acceptable salt thereof, a process for preparing the same and to a pharmaceutical composition comprising the same as an acti...
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WO/1999/059987A1 |
The present invention relates to novel compounds represented by chemical formula (1) or pharmaceutically acceptable salt thereof, a process for preparing the same and to a pharmaceutical composition comprising the same as an active ingre...
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WO/1999/059959A1 |
The invention concerns amide derivatives of Formula (I), wherein R?3¿ is (1-6C)alkyl or halogeno; m is 1-3 and R?1¿ is selected from substituents such as: (A) hydroxy, halogeno, (1-6C)alkyl, (1-6C)alkoxy, aryl, heteroaryl and heterocyc...
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WO1999048894B1 |
The present invention concerns a new general process for asymmetric hemisynthesis of harringtonines and their analogs, that are alcaloïds used in chimiotherapy. This process comprises direct esterification of a natural cephalotaxine wit...
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WO/1999/053911A1 |
Antifungal agents containing as the active ingredient compounds having a hydronaphthalene ring structure, in particular, albicanol in the hydronaphthalene ring structure moiety and sclareol, sclareolide, manool, labdanolic acid etc. bein...
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WO/1999/052886A1 |
A method for kinetically resolving a stereoisomer mixture of compounds using asymmetric epoxidation is provided. Compounds contain an olefin moiety providing one stereoisomer to be epoxidized at a higher rate than the other stereoisomer ...
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WO/1999/052855A1 |
The present invention relates to a process for preparing chiral (S)-2,3-disubstituted-1-propylamine derivatives and more particularly, to the process for preparing chiral (S)-2,3-disubstituted-1-propylamine derivatives expressed in formu...
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WO/1999/052626A1 |
A method for producing a shaped body, consisting of at least one porous oxide material, preferably a titanium silicate, and at least one metal oxide, comprising the following step (i): (i) the porous oxide material is mixed with at least...
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WO/1999/052885A1 |
The selectivity of an olefin epoxidation catalyzed by a noble metal-modified titanium or vanadium zeolite is greatly enhanced by the addition of a nitrogen compound to the reaction mixture. The epoxidation utilizes hydrogen and oxygen in...
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WO/1999/052884A1 |
The selectivity of an olefin epoxidation catalyzed by a noble metal-modified titanium or vanadium zeolite is greatly enhanced by the addition of a phosphorus, sulfur, selenium or arsenic compound to the reaction mixture. The epoxidation ...
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WO/1999/052840A1 |
The asymmetric production of pure diastereomeric (2R, 3R), (2R, 3S), (2S, 3R) and (2S, 3S)-2-aryl-1-substituted butan-2,3-diols from the derivatives of lactic acid.
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WO/1999/051557A1 |
A process for treating a mixed olefin and paraffin feedstock includes reacting, in a reaction zone and in a liquid phase, a mixed olefin and paraffin feedstock comprising an olefin and a paraffin, with a peroxidation component. Thereby i...
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WO/1999/048884A1 |
Process for epoxidation of olefinic compounds with hydrogen peroxide in the presence of solvents, preferably C¿1?-C¿8? alcohols, using silica-supported titanium catalysts, prepared by impregnation of the silica with the use of disoluti...
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WO/1999/048883A1 |
The invention concerns a continuous method for making an oxirane which consists in reacting in liquid phase an olefin with a peroxidized compound in the presence of a catalyst based on zeolite and in the presence of a solvent, and contin...
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WO/1999/048882A1 |
The invention concerns a method for making an oxirane by reacting an olefin with a peroxidized compound in the presence of a catalyst based on zeolite and in the presence of a solvent, wherein the reaction medium pH comprising the olefin...
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WO/1999/041219A1 |
Acylating agents comprising: (A) a 1,2-dicarbonyl compound or its hydroxy-reduction derivative; (B) an enzyme; and (C) at least one compound selected from among (c1) metal compounds and (c2) imide compounds such as N-hydroxyphthalimide. ...
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WO/1999/040077A2 |
The present invention relates to a method for the oxidation of unsaturated hydrocarbons in gaseous phase, wherein said oxidation is carried out in the presence of a hydrogen-oxygen mixture on a catalyst coated with gold particles. This m...
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WO/1999/039827A1 |
The invention relates to a method for regenerating supported catalysts covered with gold particles, based on titanium dioxide or titanium dioxide hydrate and used for oxidising unsaturated hydrocarbons in a gas phase. The invention is ch...
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WO/1999/038855A1 |
Highly pure optically active threo-3-amino-1,2-epoxy compounds appropriate for materials for manufacturing drugs and a process for producing the same on an industrial scale. An optically active threo-3-amino-1,2-diol derivative is subjec...
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WO/1999/036384A1 |
Alkenyldiarylmethane (ADAM) compounds have been found effective as anti-HIV agents. Novel ADAM compounds, their pharmaceutical formulations and a method of using same to treat viral infections are described.
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WO/1999/033830A1 |
A process for the preparation of the compound represented by chemical formulae (1, 2, 3, 4, 5, 6, 7, 8a, 8b, 9, 10) which is useful as a raw material for the preparation of antibiotics; and intermediates used for the preparation of the c...
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