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WO/1998/046222A1 |
Compounds and uses thereof for the preparation of pharmaceutical compositions as immunosuppressants, anticancer agents, and antiviral agents, the compound having formula (IV) where R is H, PO�3??=�, alkyl of 1 to 12 carbon atoms subs...
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WO/1998/045349A2 |
Compounds having formula (I) wherein: X is selected from formula (III); m is 1 to 6; n is 1 to 100; R�1? is selected from H, (C�1?-C�20?)alkyl, (C�1?-C�20?) alkoxy and (C�1?-C�20?)ester; and A is a saturated organic group s...
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WO/1998/045271A1 |
A process for the manufacture of a phenylthiobutyl-isoquinoline of formula (II) and novel intermediates therefor.
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WO/1998/045235A1 |
Novel cycloalkyl benzyl ether compounds represented by general formula (1) and agricultural chemicals, especially a herbicide, containing said general formula: (1) wherein R?1� and R?2� each independently represents hydrogen, a halog...
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WO/1998/045253A1 |
A series of activated iodo-benzamide derivatives are described as antineoplastic and antiviral drug compounds. The compounds generally possess a chelating group, a thio trapping group and an activating group. The presumptive mechanism of...
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WO/1998/043736A1 |
Useful catalyst compositions are produced by treating substituted molecular sieves with reactive titanium compounds such as titanium tetrahalides, preferably in the vapor phase at elevated temperatures. The molecular sieve starting mater...
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WO/1998/043735A1 |
Zeolites containing silicon, titanium and tellurium oxides are prepared by a hydrothermal method which yields materials containing exceptionally high levels of catalytically active Ti species. Following calcination, the molecular sieves ...
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WO/1998/039314A1 |
Diglycidyl ethers represented by general formula (I) (wherein R?1� and R?2� are the same or different and each represents a C�1-6? alkyl); a composition comprising the same and an epoxy resin; and a cured epoxy resin obtained by cu...
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WO/1998/038192A1 |
Disclosed are epothilones with a modified side chain.
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WO/1998/038164A1 |
Cryptophycin compounds possessing a $g(b)-epoxy moiety may be made with high stereoselectivity at various steps in the overall synthetic process. This invention also provides novel intermediates useful in preparing Cryptophycin compounds.
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WO/1998/038158A1 |
Cryptophycin compounds may be prepared utilizing an epoxidation step early in the synthetic process under the conditions set forth herein. This invention also relates to novel intermediates generated by this early epoxidation process.
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WO/1998/038184A1 |
The present invention provides a process for the epoxidation ofa protected 3-methylene-(trans)-1,2,-hydroxymethylcyclopropane with cyclohexanone and potassium peroxymonosulfate and subsequent rearrangement to provide the corresponding cy...
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WO/1998/035952A1 |
The invention relates to novel arylalkyl or arylalkyl substituted oxiran carboxylic acids of general formula(I), wherein Ar, R?3�, Y and n have the meaning cited in the description, as well as to medicaments containing them and the use...
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WO/1998/034931A1 |
Process for the preparation of compound of formula (C) wherein R�c? represents a residue comprising one or more additional groups of formula (1) by heating a compound of formula (A) or (B) at a temperature in the range of from 120 to 2...
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WO/1998/034930A1 |
Process for the preparation of compounds of the formula (A) wherein Hal represents chlorine, bromine or iodine and preferably chlorine, wherein R�a? represents a residue comprising one or more additional groups of the formula (A') from...
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WO/1998/034584A2 |
This invention relates to a method of preparing a compound of formula (I) by treating a compound of formula (II) with lithium bromide, magnesium bromide and the like.
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WO/1998/033788A1 |
A compound of formula (I), wherein W is -NHOH or -OH, R�1? is either free or protected hydroxymethyl or mercaptomethyl or derivatives thereof, R�2? is free or protected hydroxy, R�3? and R�4? is an organic group, R�5? is hydrog...
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WO/1998/033785A1 |
In a pure ethylene oxide distillation process, an aqueous mixture containing ethylene oxide, formaldehyde and at least 5 % by weight water is supplied via an inlet to a distillation device with at least one distillation column at a heigh...
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WO/1998/030552A1 |
Propylene is oxidized to propylene oxide in the vapor phase using oxygen and a supported catalyst comprising silver, gold, a potassium promoter such as potassium nitrate or potassium carbonate and a support comprised in whole or in subst...
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WO/1998/029399A1 |
The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M?+m� in sufficient numbers to ensur...
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WO/1998/029388A1 |
The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic...
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WO/1998/029877A1 |
Disclosed is a proton conductor in liquid form, comprised of a mixture of the following components: (a) a salt combined with a nitrogenated base along with an acid, according to formula (I), wherein Z�1?, Z�2?, Z�3?, and Z�4?, wh...
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WO/1998/029389A1 |
The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion...
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WO/1998/029396A1 |
The invention relates to ionic compounds in which the anionic load has been displaced, and the uses of these compounds. A compound disclosed by the invention comprises an anionic portion combined with at least one cationic portion M?+mï¿...
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WO/1998/029358A2 |
Disclosed is a method for grafting a polymer onto the surface of a carbonate material with carboxyl, amine, and/or hydroxyl functions on its surface. Said material is placed in suspension in a solution including the polymer to be grafted...
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WO/1998/029401A1 |
A method of preparing an aminoepoxide wherein a protected aminoaldehyde is reacted with a halomethyl organometallic reagent in an appropriate solvent at a temperature above -80 �C, wherein said halomethyl organometallic reagent is form...
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WO/1998/028287A1 |
The present invention relates to compounds of formula (I) (R?1� = H, CH�3?; each of the Y, which may be the same or different when x is higher than 1, represents an alkylene oxide unit of formula (a) or (b), wherein R?2� is hydroge...
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WO/1998/028286A2 |
A process of making compounds of formula (I), wherein Z is an unsubstituted or substituted n-valent cyclic moiety bearing at least one endocyclic oxirane group; Y is O, S, NH, (Ia) or (Ib); R?2� is a divalent linking group; X is O, S o...
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WO/1998/027037A1 |
1,3-difluoronapthalene derivatives of the formula (I): R�1?(-A?1�-M?1�)�a?(-A?2�-M?2�)�b?-B(-M?3�-A
?3�)�c?(-M?4�-A?4�)�d?-R?2�, in which B is (II) and R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�) and (-M?3�-...
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WO/1998/027042A1 |
5,7-difluoro-1,2,3,4-tetrahydronaphthalene derivatives of formula (I): R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�)�b?-B(-M?3�-A
?3�)�c?(-M?4�-A?4�)�d?-R?2� in which B (i) is and R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�)...
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WO/1998/027179A1 |
1,1,5,7-tetrafluoro-1,2,3,4-tetrahydronaphthalene derivatives of the formula (I): R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�)�b?-B(-M?3�-A
?3�)�c?(-M?4�-A�4?)�d?-R?2�, in which B is formula (II) and R?1�(-A?1�-M?1�)...
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WO/1998/027079A1 |
Novel compounds having reactive functional groups, represented by general formula (1); a process for the preparation of them; and uses of them. These compounds are usable as (i) actinic radiation curable resin compositions each comprisin...
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WO/1998/027038A1 |
1,3,5-Trifluoronaphthalene derivative of the formula (I): R ?1�(-A?1�-M?1�)�a?(-A?2�-M?2�)�b?-B(-M?3�-A?
3�)�c?(-M?4�-A?4�)�d?-R?2�, in which B is (1) and R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�) and (-M?3ï...
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WO/1998/027045A1 |
5,7-difluoro-3,4-Dihydro-2h-naphthalene-1-one derivatives of formula (I): R?1�(-A?1�-M?1�)�a?(-A?2�-M?2�)�b?-B(-M?3�-A
?3�)�c?(-M?4�-A?4�)�d?-R?2� in which B is (ii) and R?1�(-A?1�-M?1�)�a?(-A?2�-M?2...
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WO/1998/024429A1 |
Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.
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WO/1998/023574A1 |
The present invention relates to asiatic acid derivatives represented by formula (1), and medicines for treating wounds, which contains the same as an active component.
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WO/1998/022442A2 |
A pharmaceutical composition comprising a diaryl-cyclomethylenpyrazole compound of formula (I) wherein n is 0, 1, 2 or 3; R, R' and R'', equal to or different from each other, are H, halogen, alkylsulphonyl, aminosulphonyl and alkylamino...
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WO/1998/019983A1 |
This invention is directed to processes for producing acyclic or cyclic alcohols or glycols, carbonyls, oxiranes or aziridines from hydrocarbyl group-containing compounds, particularly lower alkanes such as methane, ethane, propane or bu...
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WO/1998/018547A1 |
A reactor (1) and process is for the production of oxirane compounds by reaction of an olefin such as propylene with an organic hydroperoxide using a solid contact catalyst, characterized by the following features: (1) the reactor (1) is...
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WO/1998/018715A1 |
The invention concerns a method for regenerating a working solution for producing hydrogen peroxide 30 %, in which the working solution is contacted with aluminium, said aluminium being derived from a working by drop coagulation or by ex...
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WO/1998/017640A1 |
Hydrogen peroxide adducts of phosphine oxides and equivalents for As, Sb and Bi and or phosphonates and phosphinates. Methods of preparation of said adducts by reaction of hydrogen peroxide on the phosphine oxides, equivalents for As, Sb...
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WO/1998/015584A1 |
Glycidyl methacrylate - alkylene (pref. butadiene) - glycidyl methacrylate triblock copolymers of potentially interesting reactive character. These epoxy-modified methacrylate triblocks may be useful for making oil-extended gels and poss...
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WO/1998/015544A1 |
A compound and method for producing an enantiomerically enriched epoxide from an olefin using a chiral ketone and an oxidizing agent is disclosed.
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WO/1998/012171A1 |
A process for the preparation of 3-amino-2-hydroxy-1-propyl ethers of general formula (4), (wherein R?1� is alkyl, or an aromatic or heterocyclic group; and R?2� and R?3� are each hydrogen or alkyl, or alternatively they together w...
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WO/1998/012186A1 |
A process for the preparation of glycidyl ethers, characterized by reacting an epoxy compound represented by general formula (1) with an alcohol in the presence of a fluorine salt, wherein X is halogeno or sulfonyloxy. The process makes ...
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WO/1998/009974A1 |
This invention provides processes for preparing intermediates useful for the preparation of cryptophycin compounds.
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WO/1998/009935A1 |
A process for preparing a compound having structure (I) wherein n is an integer from 1-5; each of R�1? and R�2? independently is optionally substituted C�1?-C�6? alkyl; each of W and X is independently hydrogen or C�1?-C�6? a...
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WO/1998/008812A1 |
This invention provides processes for preparing cryptophycin compounds and novel intermediates which are useful in such processes.
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WO/1998/007690A1 |
The present invention relates to a process for stereoselective preparation of (3R,4R)-4-acetoxy-3-{[(1'R)-1'-t-butyldimethylsilyloxy]ethyl
}-2-azetidinone (I) which is a useful intermediate for preparing carbapenem and penem type $g(b)-l...
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WO/1998/007691A1 |
The present invention relates to a process for stereoselective preparation of (3S,4S)-3-[(1'R)-1'-hydroxyethyl]-4-alkoxycarbonyl-2-azetidi
none (I) which is a useful intermediate for preparing carbaphenem and phenem type $g(b)-lactam ant...
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