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JP3290623B2 |
To obtain a new tubular compound similar to a carbon nanotube, especially a compound having a controlled diameter and a controlled length, by a relatively simple chemical synthesis method using a calix arene known as a kind of cyclic com...
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JP3290592B2 |
To obtain a new dioxetane generating chemical luminescence by triggering with an enzyme-containing chemical reagent, also improving solubility to an aqueous solution, having excellent stability, and useful as a substrate for a marker enz...
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JP2002515428A |
The present invention provides diacyl carbohydrazide compounds, and pharmaceutically acceptable salts, hydrates and solvates thereof, which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, novel in...
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JP2002515481A |
A method of modifying or altering the structure of a 1alpha-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a chair conformation that presents the 1alp...
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JP3280342B2 |
To obtain the subject compound readily handleable and useful as a producing intermediate of substituted dioxetanes usable for an assay method by reacting a specific compound with a specific alkylating agent in a polar aprotic solvent in ...
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JP2002511113A |
PCT No. PCT/FR98/01386 Sec. 371 Date Mar. 21, 2000 Sec. 102(e) Date Mar. 21, 2000 PCT Filed Jun. 29, 1998 PCT Pub. No. WO99/00441 PCT Pub. Date Jan. 7, 1999The invention concerns monomers with dilactonic cycle and the corresponding polym...
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JP3273657B2 |
PURPOSE: To obtain a vinylcyclopropanone cyclic acetal compound, capable of carrying out the ring opening polymerization or cross-linking and providing a low volume shrinkage therein and useful as a raw material for various molding, comp...
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JP2002508654A |
Probes labeled with 1,2-dioxetane precursors can be employed in a variety of assays. The probes may be nucleic acid, peptide nucleic acid, proteins including enzyme, antibody or antigen, steroid, carbohydrate, drug or non-drug hapten. Th...
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JP3262333B2 |
This invention concerns compounds of formula (I) in optionally substituted by lower alkyl; Z is a bicyclic oxygen-containing aryl radical (e.g. 2,3-dihydro-1,4-benzodioxin-5-yl); R is hydrogen or lower alkyl; R1 is aryl or aryl(lower)alk...
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JP2002502832A |
The present invention relates to methods for preparing macrocyclic products having 9 or more ring atoms by ring-closing diyne metathesis of suitable diyne substrates. The diyne substrates can be converted into cycloalkynes or into cycloa...
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JP2002020382A |
To provide a new 1,2-dioxetane derivative useful as a reagent for chemiluminescent immunoassay(CLIA).1,2-Dioxetane derivative of the formula (1) (wherein, R1 is H, a halogen or a 1-3C alkyl; R2 is a hydroxyl-substituted 2-4C alkoxyl or a...
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JP3247773B2 |
PURPOSE: To provide an efficient method for production of a phenol having a substituent group according to a reaction exhibiting a high raw material conversion in a shorter time in comparison with the conventional method. CONSTITUTION: I...
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JP3244659B2 |
To separate the subject microorganisms having antimicrobial activity by culturing a microbial suspension in a solid Growth medium for Lactobacillus lactis followed by laminating the system with a carbon source-contg. liquefied semi-solid...
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JP3233476B2 |
PURPOSE: To provide a new compound having inhibitory activity against cholesterol acyl transferase-acyl coenzyme A, thus useful for curing or preventing diseases due to cholesterol accumulation such as hyperlipemia. CONSTITUTION: The com...
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JP2001516781A |
Monoesters and macrocyclic diesters of 2,2,4-trimethyl-1,3-pentanediol and phthalic acid or a derivative thereof are described. Methods by which such monoesters and diesters may be prepared are also described. The mono- and diesters acco...
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JP2001515897A |
A method of treating ocular hypotension, hypertension, hemorrhage, myocardial ischemia, angina pectoris, coronary contraction, cerebrovascular contraction after subarachnoidal hemorrhage, and asthma which comprises administering to a mam...
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JP2001240598A |
To provide 7-oxahexadecanolide, its intermediate, a composition containing 7-oxahexadecanolide or the intermediate, a method of producing them and a perfume compound containing 7-oxahexadecanolide.6-Hydroxyhexanic acid or its ester and b...
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JP3199752B2 |
Compounds of formula (I), (I) wherein R1 and R2 are independently hydrogen, unsubstituted lower alkyl or lower alkyl substituted by lower alkoxy or lower alkyl thio, or acyl which is unsubstituted or substituted by one or more of lower a...
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JP2001510838A |
The present invention provides compound of the formula:wherein R1 and R2 are the same or different and are independently H, C1-C6 straight-chain or branched saturated or unsaturated alkyl, aryl, R6CH2-, R6CO-, or R6SO2-, wherein R6 is H,...
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JP2001181274A |
To obtain a new macrocyclic oxalactone highly useful as a perfume. This compound is represented by the formula and has an extremely desirable, fresh floral musk smell and other advantageous characteristics of stability and application of...
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JP2001089469A |
To provide a method for readily preparing 4,4'-bicyclohexanedione monoketals in high yield by using industrially easily available 4-(4'- hydroxyphenyl)cyclohexanone ketals as a starting material. 4-(4'-hydroxyphenyl)cyclohexanone ketals ...
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JP3148987B2 |
To provide the subject novel C60 fullerene compound that solves the defects of a linear type C60 fullerene compounds, and is a novel opposition type donor-acceptor compound and is useful as an element for electronic devices, optical devi...
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JP2000515479A |
The use of inorganic or organic poly acids is claimed for treating mineral fertilisers containing a nitrification inhibitor. The use of compounds of formula (I) is claimed as nitrification inhibitors. R1 = H, halo or 1-4C alkyl; R2 = 1-4...
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JP3086059B2 |
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JP3082374B2 |
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JP3075558B2 |
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JP3071030B2 |
Ketals, preferably glycerol ketals such as, for example, 1-menthone glycerol ketal or 3,3,5-trimethylcyclohexanone glycerol ketal, have a physiological cooling effect and are therefore suitable as active compounds in compositions which a...
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JP3072334B2 |
The practicality of known depolymerization reactions in which there is a danger of building up adherent residues on heat transfer surfaces is greatly improved by performing the process under conditions that provide a driving force which ...
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JP2000169467A |
To efficiently obtain the subject compound by reaction between a specific biaryldicarboxylic acid dihalide and a specific oxoalkanediol.This compound of formula III is obtained by reaction between a biaryldicarboxylic acid dihalide of fo...
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JP2000169468A |
To obtain the subject new compound, a specific dihydrobenzodioxepin compound, exhibiting selective antagonism against muscarine M3 receptors, and useful in dealing with urologic diseases including pollakisuria, incontinence of urine and ...
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JP2000169465A |
To obtain the subject compound in high selectivity and in high yield with effectively preventing generation of byproducts and polymerization by isomerizing a specific alkenyl compound in the presence of a stabilizer and an isomerization ...
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JP2000169466A |
To obtain the novel subject compound improved in preservation stability without damaging polymerizability by coexisting a radical polymerization inhibitor and/or a basic compound with a specific cyclic alkylidene acetal.This stabilized c...
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JP3046840B2 |
Novel hydroxy containing fluorovinyl ethers, polymers of hydroxy containing fluorovinyl ethers, novel cyclic ethers, copolymers of selected hydroxy containing fluorovinyl ethers, a process for reducing ester containing fluorovinyl compou...
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JP3036713B2 |
PURPOSE: To provide a reaction solution having lower viscosity and ready handleability and to obtain a cyclic carbonate simply in high yield and in high selectivity in reacting a carbonic acid ester with a diol by using a specific amount...
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JP3034868B2 |
To obtain a chemiluminescent, water-soluble 1,2-dioxetane derivative capable of emitting optically detectable electromagnetic energy through its decomposition in a water-miscible medium, thereby useful in e.g. bioassays by purifying a sp...
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JP3025280B2 |
Compounds having formula (I), wherein T is a polycycloalkylidene group (e.g., adamant-2-ylidene); R is a C1-20 alkyl, aralkyl or cycloalkyl group; and Y is a fluorescent chromophore (e.g., m-phenylene), produced by reacting a compound ha...
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JP2000502989A |
Dioxetanes that can be triggered by bases are provided which can be used to detect bases in organic solvents, aqueous preparations and detect gaseous bases in the atmosphere. The dioxetanes can be used to detect the release of bases from...
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JP3010067B2 |
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JP2000038384A |
To obtain the subject monoacetal compound in a high yield by specifying an initial distillation temperature on isolating glutaraldehyde monoacetal by a distillation from a crude reaction liquid obtained after reacting dihydropyranes with...
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JP3006891B2 |
PCT No. PCT/US96/09248 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Jun. 19, 1996 PCT Pub. No. WO97/00869 PCT Pub. Date Jan. 9, 1997A process for producing a stable triggerable dioxetane comprising; (a) reacting a...
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JP3007092B2 |
Antibiotic is produced by placing cells of Lactobacillus reuteri (LR) under conditions suitable for prodn. Pref. process is carried at in the presence of glycerol, and with a reduced oxygen tension. Also claimed is an antibiotic and its ...
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JP3004561B2 |
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JP2999810B2 |
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JP3000240B2 |
Alkoxyoxime-substituted phenyl-glyoxylic acid alkyl ester derivatives of formula (IIIc) are new. R1 = 1-4C alkyl; R2 = 1-2C alkyl; and U = leaving group. Also claimed is the use of (IIIc) to prepare oxime ethers of formula (I). Y-X = CH3...
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JPH11349584A |
To obtain a hydroxylactone compound that is used as a precursor of a ketone to be used as a catalyst in the synthesis of optically active phenylglycidic acid derivatives by subjecting an epoxy derivative of a diaryl compound to intramole...
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JPH11335342A |
To obtain a 1,2-dioxacene suitable for production of substituted 1,2- dioxetanes and useful as a readily handleable intermediate. This compound is represented by the formula [T is a group forming a stabilizing group which is a cycloalkyl...
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JPH11335372A |
To provide a process for the production of a carbonate compound in extremely high reactivity and selectivity without generating harmful waste materials and, accordingly, suitable for the mass-production of a carbonate compound on an indu...
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JPH11315077A |
To produce a macrocyclic ester useful as an odoriferous component or a fixative in an odoriferous substance mixture by heating a specific dicarboxylic acid-bis(glycol) ester, a glycol and a reactional medium in the presence of a catalyst...
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JPH11315076A |
To produce a macrocyclic ester useful as an odoriferous composition or as a fixative in an odoriferous substance mixture by cyclizing a specific dicarboxylic acid-bis(glycol) ester. (A) A dicarboxylic acid-bis(glycol) ester represented b...
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JPH11315075A |
To produce a 2-alkenyl-1,3-dioxo compound useful as a perfume, a raw material for medicines and agrochemicals, an organic synthetic intermediate or a polymeric material by reacting a specific unsaturated aldehyde with a specified hydroxy...
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