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WO/2014/141164A1 |
The present invention relates to a method of recovering lactose from a lactose- containing liquid source comprising providing a lactose-containing liquid source, crystallising the lactose in the lactose-containing liquid source to genera...
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WO/2014/144209A1 |
The present invention is a new non-obvious method for the improved and simplified purification of nucleic acids. Nucleic acid purification typically consists of a lysis step to release nucleic acids from a sample, the binding of the nucl...
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WO/2014/144767A1 |
The current landscape for preparative chromatographic RNA purification uses reversed phase HPLC, but this technique presents many issues with process scale up and ion exchange for preparative purification has only been used for short RNA...
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WO/2014/135167A1 |
A method of purifying a hydrophilic oligosaccharide, preferably a human milk oligosaccharide, in an aqueous medium from a fermentation or enzymatic process. The method involves: a. clarifying the aqueous medium to remove particulates and...
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WO/2014/126471A1 |
Lignocellulosic biomass can be fractionated for the purpose of increasing cellulose purity in the pulp, increasing native lignin content of the isolated lignin, and improving cellulose hydrolysis, by performing the steps of: (a) extracti...
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WO/2014/121590A1 |
Flavonoids compounds of formula (I) or isoflavonoids compounds of formula (II), useful for treatment of HCV diseases, are disclosed. In the compounds, R1 is selected from formula(III), formula(IV) or formula(V); R2, R3, R4, R5 are select...
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WO/2014/121424A1 |
Provided are a sodium hydroxysafflor yellow A compound of formula I and the production method and pharmaceutical use thereof. Sodium hydroxysafflor yellow A having a purity above 98.5% is obtained through extraction, transferring to a so...
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WO/2014/116813A1 |
An apparatus for isolating nucleic acids includes an elongated body. The elongated body includes a silica surface positioned and configured to bind the nucleic acids when the elongated body is dipped into a biological material sample.
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WO/2014/106856A1 |
The present invention relates to the mannose - receptor selective lysinylated cationic amphiphile and a process for preparation thereof. The compounds of the present invention can target DNA vaccines to antigen presenting cells (APCs) su...
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WO/2014/101865A1 |
Disclosed are a composition of glucose derivative and proline, a crystal, a preparation method, and an application. In an X-ray powder diffraction diagram of an eutectic crystal, when the diffraction angle is 2θ, characteristic diffract...
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WO/2014/105289A1 |
In some variations, the invention provides a process for producing furfural, 5- hydroxymethylfurfural, and/or levulinic acid from cellulosic biomass, comprising: fractionating the feedstock in the presence of a solvent for lignin, sulfur...
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WO/2014/094544A1 |
Provided are a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, pharmaceutical composition containing same, and uses thereof in the preparation of drugs for treati...
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WO/2014/095771A1 |
Saccharide conjugate vaccines which use diphtheria toxoid or tetanus toxoid as a carrier protein can confer protection against lethal challenge by diphtheria toxin or tetanus toxin. Thus, in addition to protecting against the bacteria wh...
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WO/2014/094312A1 |
Disclosed is a method for synthesizing nucleoside amino acid derivatives through enzyme catalysis, which comprises the step of: under the catalysis of protease or lipase, nucleoside compounds and L-amino acid ester reacting to obtain nuc...
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WO/2014/094405A1 |
Disclosed is a method for extraction and preparation of avermectin B2a. The method comprises: an avermectin fermentation solution is prepared into a dry mycelium and leached; a leach liquor is concentrated, and extraction agents such as ...
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WO/2014/100685A1 |
The present disclosure provides methods and systems for generating sugars from biomass. The methods and systems provide increased yields of carbohydrates and fermentable sugars by combining enzyme recycling with removal of saccharificati...
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WO/2014/092992A1 |
The present invention provides methods for producing a mixture of sugars from a solid biomass feedstock using a counter current extraction apparatus and a dilute acidic solution.
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WO/2014/086373A1 |
The present invention relates to a method of obtaining a non-acidic human milk oligosaccharide (HMO) or a precursor in crystalline form from an aqueous medium, such as a fermentation broth, by drying the aqueous medium and then treating ...
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WO/2014/085958A1 |
The erythromycin derivatives of the present invention, i.e., hydrated crystals of erythromycin stearate, has low moisture absorption and good storage stability, and is suitable for preparing drugs for treating and preventing infectious d...
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WO/2014/079300A1 |
The present invention relates to a method for preparing highly pure doxorubicin. The method comprises the following steps: (1) chromatographing a prepurified doxorubicin solution by using macroporous resin, pre-washing the chromatographe...
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WO/2014/075563A1 |
Disclosed is a preparation method of antimicrobial traditional Chinese medicine compound total flavonoid. The traditional Chinese medicine compound total flavonoid prepared by using the method has an antimicrobial effect. Also disclosed ...
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WO/2014/076490A1 |
A process for preparing phosphoramidates of nucleosides where a desired enantiomer, having regard to the asymmetric chiral centre of the phosphorus atom P, is provided in an enriched amount. The process comprises admixing a nucleoside wi...
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WO/2014/074066A1 |
The present invention describes a process for quenching a hydrothermal, dilute acid hydrolysis reaction of a biomass feedstock, wherein degradation of an aqueous monomer and/or oligomer sugar mixture is slowed down or stopped by flash co...
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WO/2014/068208A1 |
The present invention concerns a method for producing sophorose from a sophorolipid which involves carrying out a step of hydrolysis of the sophorolipid in an aqueous medium in the presence of an acid compound.
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WO/2014/063441A1 |
The present invention relates to a use of a triterpene derivative of formula (I) for producing drugs which can be used for the prevention or treatment of influenza diseases, wherein the substituents are as defined in the specification. T...
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WO/2014/059436A1 |
Site-selective functionalization of Amphotericin B has been achieved by simply modifying the electronic nature of the reagents. A Hammett analysis is consistent with linking of this phenomenon to the Hammond postulate: electronic tuning ...
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WO/2014/055726A1 |
The GreenBox+ technology is suitable to extract hemicellulose sugars prior to pulping of biomass into pulp products. The revenue obtainable from the sugar stream can significantly improve the economics of a pulp and paper mill. An initia...
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WO/2014/053897A1 |
A method of preparing purified decitabine comprises mixing crude decitabine with solvent, such as dimethylacetamide, to form a solution or suspension and forming the purified decitabine from the solution or suspension. The forming step c...
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WO/2014/047117A1 |
Processes for the production of nucleoside phosphoramidate compounds having the following Formula I are provided.
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WO/2014/040066A1 |
Highly specific and novel solid phase methods for analyzing glycans and proteoglycans using a solid phase system are provided. The present invention also provides an integrated apparatus and methods of use which comprises a high-throughp...
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WO/2014/033311A1 |
The present invention relates to isomerization of C4-C6 aldoses to their corresponding C4-C6 ketoses. In particular, the invention concerns isomerization of C4-C6 aldoses over solid zeolite catalysts free of any metals other than aluminu...
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WO/2014/025272A1 |
The subject of the invention is a new method of the synthesis of polyphosphate analogues, such as nucleosides, oligonucleotides, carbohydrates, peptides and proteins, which are of biological importance and are used in organic chemistry, ...
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WO/2013/190531A9 |
A method for modifying galactosyl disaccharides in order to enhance their bifidogenic effect, comprising reacting at least one glycosyl donor with a precursor galactosyl disaccharide or a mixture of precursor galactosyl disaccharides usi...
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WO/2013/176738A9 |
Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and X are described. The method includes expression of UDP-glucosyltransferases from Stevia rebaudiana Bertoni, which are capable converting certain...
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WO/2014/016374A1 |
The present invention provides methods for purifying at least one saponin in a solution comprising the steps of: (a) providing at least one saponin in a first solvent comprising a solubilizing component; (b) replacing at least a portion ...
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WO/2014/014670A1 |
The present invention provides synthetic Pseudomonas aeruginosa lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various P. aeruginosa serotype-specific oligosaccharide antigens or various core P. aeruginosa oli...
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WO/2013/189237A1 |
Disclosed are a novel andrographolide derivative and analogue as well as a preparation method of the novel andrographolide derivative and analogue and an application to the treatment, the prevention and the relief on human viruses and ne...
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WO/2013/191549A1 |
The invention relates to the field of carbohydrate chemistry. Provided is a process for the regioselective oxidation of a single secondary hydroxy function of a carbohydrate substrate comprising two or more secondary hydroxy functions, c...
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WO/2013/190529A1 |
A method for modifying galactosyl disaccharides in order to enhance their bifidogenic effect, comprising reacting at least one glycosyl donor with a precursor galactosyl disaccharide or a mixture of precursor galactosyl disaccharides usi...
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WO/2013/185780A1 |
The present application discloses a method for enhancing the stability of a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend when stored for extended periods at temperatures above 25 °C by spray-drying an aqueous solut...
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WO/2013/184091A1 |
Methods for purifying and extracting compounds from a mixture are provided using a solvent-free mechanochemical method. Methods for purifying and/or extracting sugars, amino acids, and, the like, from a mixture are also provided, using a...
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WO/2013/178571A1 |
An improved process for the preparation of (2'R)-2'-deoxy-2'-fluoro-2'-methylcytidine derivatives of formula I, (I), wherein R1 is selected from C1-4-alkyl is described. The (2'R)-2'-deoxy-2'-fluoro-2'-methylcytidine derivatives of formu...
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WO/2013/177985A1 |
A nitrogenous heterocyclic imide derivative having obvious insecticidal activity, and preparation method and uses thereof; the nitrogenous heterocyclic imide derivative and pharmaceutically acceptable salt thereof have been proved in pra...
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WO/2013/177058A1 |
Disclosed is a process for the production of d-tagatose from lactose after acid hydrolysis to provide a hydrolysate having 1 equiv of d-glucose and 1 equiv of d-galactose for each unit of lactose converted. More particularly, the inventi...
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WO/2013/169029A1 |
The present invention relates to a method for preparing high purity anhydrosugar alcohols using hydrogenated sugar, and more specifically, to a method for preparing high purity anhydrosugar alcohols (particularly, isosorbide, isomannide,...
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WO/2013/169028A1 |
The present invention relates to a production method for an anhydro sugar alcohol having a markedly reduced ion content and improved colour characteristics, and, more specifically, relates to a method for producing an anhydrous sugar alc...
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WO/2013/165308A1 |
The present invention describes a process involving liquefaction of a biomass slurry by treatment in hot compressed water (HCW), said process comprising: -a first decomposition step being performed at an average pH level of at most 4.5, ...
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WO/2013/158092A1 |
The present invention provides a method of isolating nucleic acid and protein from the same biological sample, comprising, in the following order: a) disrupting the biological sample; b) contacting the disrupted biological sample of (a) ...
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WO/2013/152470A1 |
The present invention provides new ethyl salicylate glycosides compound, a synthetic method thereof, pharmaceutical compositions containing the ethyl salicylate glycosides compound, and applications of the ethyl salicylate glycosides com...
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WO/2013/152279A1 |
The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).
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