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JPH0680657A |
PURPOSE: To efficiently obtain an axial-hydroxyglycal in high yield useful for intermediates or the like of an esperamicin an DNA cutting antibiotics or the like by reacting a substituted glycal compound having an equatorial ester group ...
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JPH06502179A |
Glycosyl phosphate triesters are prepared by reacting an anomeric mixture of a substituted hexopyranose with 4-N,N-dimethylaminopyridine and diphenyl chlorophosphate wherein using a specific order of addition determines the stereochemist...
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JPH0665273A |
PURPOSE: To obtain a method for improving sulfation ratio of a hydroxyl group as a method for sulfating saccharide. CONSTITUTION: The objective method for producing sulfated saccharide is characterized by as a raw material using sacchari...
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JPH0656867A |
PURPOSE: To crystallize an α-anomer into a pure form and to separate the compd. of the title by bringing an anomer mixture into contact with a solvent, heating, adding a counter solvent and decreasing the temp. CONSTITUTION: An anomer m...
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JPH0656864A |
PURPOSE: To efficiently prepare the deriv. having excellent steric selectivity and useful for the intermediate of antiviral substances in high yield by bringing a specified lactol into contact with an acid scavenger and a sulfonating rea...
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JPH0641200A |
PURPOSE: To produce the new conjugate antigen covalent with a carrier protein via specified D-glucosammine disaccharide as a binder and useful as vaccines for preventing septic shock caused by bacterial endotoxins. CONSTITUTION: D-glucos...
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JPH0625304A |
PURPOSE: To provide a novel galactosamine polymer sulfate comprising a sulfate derivative produced by chemically modifying a galactosamine polymer and having an antiviral activity, and to provide an antiviral agent comprising the same as...
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JPH05331132A |
PURPOSE: To provide a new sulfate useful as an intermediate for the synthesis of a sulfamate showing excellent anticonvulsive activity and useful for diseases such as epilepsy glaucoma. CONSTITUTION: The compd. is a chlorosulfate express...
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JPH05320183A |
PURPOSE: To obtain a new compound, useful as a precursor of high-purity fructose-diphosphate which is a medicine or an intermediate therefor and readily available in high purity and yield. CONSTITUTION: The dizinc salt of fructose-1,6-di...
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JPH0582393B2 |
Disaccharide derivatives represented by the formula (I): wherein R<1>CO- and R<2>CO- each represents a residue of a straight chain fatty acid having from 8 to 20 carbon atoms and having a hydroxyl group at the 3-position thereof; R<3>CO-...
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JPH0576927B2 |
Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents, wherein the sucralfate is present in the form of a gel having self-suspending properties and is suspended in an aqueous carbohydrate solu...
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JPH05271269A |
PURPOSE: To purify the subject compound useful as pharmaceuticals, etc., by subjecting a liquid containing fructose-diphosphate to anion exchange chromatography and desalting the treated liquid. CONSTITUTION: A liquid containing fructose...
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JPH05506780A |
An essentially pure substance has a structure of a Nod factor or one of its analogues. The Nod factor is characterized by the fact that its biosynthesis is controlled by at least one nodulation gene ($i(nodA,B,C)) common to the Rhizobiac...
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JPH0570635B2 |
This invention provides a novel compound having a formula such asorThis invention also provides a process for preparing such a compound. The novel compound has an excellent immunological activity.
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JPH0569117B2 |
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JPH05247078A |
PURPOSE: To provide a new sugar compound useful for the subject excellent inhibitor capable of inhibiting inflammation or allergic reactions. CONSTITUTION: The objective sugar compound of formula I [R1 is H, (substituted) aliphatic hydro...
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JPH0566392B2 |
Process for the organic synthesis of oligosaccharides forming or corresponding to fragments of acid mucopolysaccharides wherein two compounds comprised of or terminated respectively by patterns of galactosamine structure and patterns of ...
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JPH0565517B2 |
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JPH0558439B2 |
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JPH0555111B2 |
An antibiotic complex designated herein as BBM-1675 complex is produced by fermentation of certain novel strains of Actinomadura verrucosospora. The complex may be separated into two major components, BBM-1675A1 and A2, and four minor co...
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JPH05202083A |
PURPOSE: To provide a new compound having low toxicity and useful as immunoactivation agent, antitumor agent, etc. CONSTITUTION: The compound of formula I (R1 to R3 are H or OH; l and m are 6-14), e.g. 2-deoxy-4,6-O-hydroxyphosphoryl-2-t...
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JPH05170782A |
PURPOSE: To prepare newly the subject compound having antiviral activity, etc., by allowing a specific compound to react with propargyl alcohol, and then allowing to react by adding lithium aluminum hydride, etc. CONSTITUTION: The compou...
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JPH0542438B2 |
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.
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JPH0541606B2 |
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JPH0535130B2 |
The invention relates to formulations in the form of suspensions containing sucralfate, characterized in that they contain, based on the sucralfate, 1-5% by weight of xanthan gum and 1-12.5% by weight of at least one peptiser.
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JPH05502870A |
The present invention relates to a pharmaceutical composition and to the use of a compound of formula (I): (OH)6-p-(C4+nH5+mO)-(OPO3H2)p, where n=1, 2 or 3, m=1, 2 or 3, p=1, 2 or 3 for the preparing of a medicament for preventing, allev...
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JPH0595765A |
PURPOSE: To provide the title flavor improver for esp. starch-contg. hot-cooked foods like bread, cakes or 'tempra' (deep-fried fish and vegetables), containing a sugar phosphoric ester, polyol phosphoric ester, etc. CONSTITUTION: The ob...
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JPH0578382A |
PURPOSE: To obtain a new compound having antiviral activity and very low toxicity. CONSTITUTION: A compound of an alkyloligosaccharide sulfate in which the hydrogen of hydroxyl group at the 1-position of the terminal saccharide of an oli...
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JPH0521089B2 |
A preventive and therapeutic method for hypertension by dosing hexose phosphate calcium which produces an immediate effect without having any undesirable side-effects to control a rise in the blood pressure, and is efficacious also for v...
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JPH0515719B2 |
A pharmaceutical composition containing as a pharmaceutically active ingredient at least one isomer of inositol triphosphate (IP3) in an amount sufficient to reduce the negative effect of cadmium or aluminium in the body or inhibit or re...
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JPH0539223A |
PURPOSE: To avoid pollution from production environment and obtain the subject stock suspension by forming an aluminum salt, then dispersing the resultant reactional product in an aqueous medium without separating a solid from a liquid a...
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JPH055824B2 |
Sulfamates of the following formula (I):wherein X is O or CH2 and R1, R2, R3, R4 and R5 are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further...
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JPH059192A |
PURPOSE: To obtain the subject compound having excellent moisture-retention, producible at a low cost and useful as an ingredient of shampoo, rinse, etc., by reacting a phosphoric acid ester with an epoxy compound. CONSTITUTION: The obje...
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JPH0480918B2 |
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JPH04506656A |
A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or ...
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JPH04321696A |
PURPOSE: To obtain the title compound to be used e.g. as an intermediate for synthesizing antineoplastically active substances without substrate degradation, by reaction in an aprotic solvent, between 2-deoxyamino sugar and a halogenodic...
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JPH0469637B2 |
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JPH0469159B2 |
Sugar phosphate of the following general formula (I): (I) is prepared by reaction between a phosphoric monoester and a glycidyltriammonium salt. The sugar phosphate according to the invention has good moisture retention and good adsorpti...
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JPH04312598A |
PURPOSE: To stereoselectively obtain the compd. which yields extremely high- purity GDP-fucose by converting a protective L-fucose to an O-(α-fucopyranosyl) trichloroacetoimidate and bringing the same into reaction with org. phosphate, ...
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JPH04297485A |
PURPOSE: To provide a new compound useful as an intermediate for lipid A exhibiting antitumor activity. CONSTITUTION: The compound of formula I {Y1 is H, (substituted) alkyl, (substituted) alkenyl or (substituted) benzyl; Y2 is protectin...
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JPH0463861B2 |
1. Use of sucralfate for controlling emesis and/or diarrhoea in veterinary medicine.
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JPH04283599A |
PURPOSE: To produce a glycoside-based compound of glucuronic acid derivative using a stable glycosyl donor capable of long-term storage without using a heavy metal as an activating agent. CONSTITUTION: A thiophosphinic ester derivative o...
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JPH0460119B2 |
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JPH0460118B2 |
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JPH0460120B2 |
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JPH04266896A |
PURPOSE: To extremely readily fractionate an oligosaccharide by the once employment of a chromatography comprising a HPLC using an anion exchange resin column. CONSTITUTION: A method for purifying an oligosaccharide containing an alginic...
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JPH04234895A |
PURPOSE: To obtain a 6-position substituted lipid A relative substance useful for immunoactivator, antitumor agent, etc., similar to lipid A of activity manifestation center of lipopolysaccharide, having mitogen activity, tumor necrosis ...
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JPH04226996A |
PURPOSE: To obtain a new phosphobetaine being excellent in moisture-retaining properties and inexpensive and useful as a base of hair or skin cosmetic, etc., and humectant, etc. CONSTITUTION: A compound e.g. α-D-glucopyranose-1-[ 2-hydr...
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JPH0446281B2 |
Complexable heterogeneous oligosaccharides and pure alpha-hydosanes, namely not contaminated from other macromolecules (mucopolysaccharides, proteins, nucleic acids, etc.) of a defined molecular weight, are produced starting from a mixtu...
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JPH04503950A |
A glycosaminoglycoside (GAG) composition predominantly of tetrasacchardie units derived from heparin/heparan sulfate has enchanced activity in preventing the proliferation of smooth muscle cells. This GAG preparation is useful in the tre...
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