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JPS5782319A |
PURPOSE: An antitumor agent containing a saponin constituent in the terrestrial part of a medicinal ginseng as an active constituent, and suitable for the oral administration without exhibiting the toxicity and hemolytic action. CONSTITU...
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JPS5762297A |
NEW MATERIAL:A compound obtained by including a digitalis cardiac glycoside, e.g. digoxin or digitoxin, in cyclodixtrin. EXAMPLE: Digoxin-γ-cyclodextrin inclusion compound. USE: A digitalis cardiotonic agent having good stability and so...
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JPS56169697A |
Immunologically active compounds of the formula: (I.) hydrogen; C1-30 alkyl; C2-30 alkenyl; C1-30 alkoxy; phenyl; C1-20 alkylsulfonyl; or cholesteryl; and R4 may additionally be hydrogen; R5 is hydrogen; or R5-R6 together is -CH2-CH2-CH2...
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JPS56158800A |
PURPOSE: To obtain a saponin which is regarded as the same compound as that of the saponin component of a ginseng, by extracting Gynostemma pentaphyllum Makino, a cucurbitaceous plant, with water or water-containing lower alcohol, subjec...
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JPS56127398A |
PURPOSE: To separate the titled glucoside useful as pharmaceuticals such as hemostatic agent, blood vessel reinforcing agent, antishock agent, antiphlogistic agent, etc., in high purity, by the reprecipitation of crude sterol glucoside w...
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JPS56127397A |
PURPOSE: To separate the titled glucoside useful as pharmaceuticals such as hemostatic agent, blood vessel reinforcing agent, antishock agent, antiphlogistic agent, etc., by acylating crude sterol glucoside, crystallizing the acylated gl...
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JPS56127098A |
PURPOSE: To prepare a saponin derivative useful as a raw material of other compounds and known saponin compounds, by eliminting at least one saccharide from the substutuent at a specific position by the enzymatic hydrolysis of saponin, a...
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JPS56125400A |
NEW MATERIAL:A reduction product of an extract from Marsdenia cundurango Reichenbach fil. which is soluble in lower alcohols and chlorinated hydrocarbons other than carbon tetrachloride and insoluble in aliphatic hydrocarbons, carbon tet...
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JPS56123998A |
NEW MATERIAL:A cundurango extract soluble in lower alcohols and chlorinated hydrocarbon except CCl4 and insoluble in CCl4 or aromatic hydrocarbons. Appearance: brown to light brown powder. Taste: bitterness. Offensive. It produces a smel...
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JPS56113799A |
NEW MATERIAL:An oxygenated sterylglucoside derivative of formula I (R1, R2, R3 and R4 may be the same or different H or lower alkanoyl; Y is formula VI or VII; R5 is 4-methylpentyl, 3-ethyl-4-methylpentyl, etc.). EXAMPLE: (7-Ketocholeste...
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JPS5692300A |
For the Contracting States : BE, CH, LI, DE, FR, GB, IT, NL 1. A C3 -branched cardenolideglycoside of the formula (I) see diagramm : EP0030331,P7,F1 where R**1 is a hydrocarbon radical of up to 4 carbon atoms, or phenyl, R**2 is hydrogen...
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JPS5681597A |
Phosphorylmuramyl peptides of the formula are immuno-potentiating. In the formula, R1 represents optionally substituted alkyl or aryl, R2, R4, R6 and R7 represent, for example, hydrogen, R3 represents hydrogen or lower alkyl, R5 represen...
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JPS5663997A |
NEW MATERIAL:12β-[ (3,4-Dimethyl-1-0-2-pentenyl)oxy ]-3β-[ ( 2, 6-dideoxy-3- 0-methyl-ribo-hexyl-( 1→4 )-2,6-dideoxy-3-0-methyl-ribo-hexyl( 1→4 )-2,6-dideoxy- 3-0-methyl-ribo-hexyl)-oxy]-3β-8,14β-trihydroxypregn-5-en-
20-one of f...
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JPS5663998A |
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JPS5653698A |
Compounds of the formulae Y-R wherein Y is 1-thio-B-L-fucose, 1-thio-B-D-galactose or 1-thio-B-lactose and R is 2-(1- adamantyl) ethyt, 3- [(p-tetrafluorophenethyl) phenyl] propyl, 6-(5-cholesten-3B-yloxy) hex-3-ynl, oleyl, or hexadecyl ...
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JPS56500611A |
The invention provides new vitamin D derivatives as well as new intermediate compounds derived during the processes for preparing such new derivatives. The new derivatives have been identified as 1 alpha -hydroxy-25-keto-27-nor-vitamin D...
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JPS5616160B2 |
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JPS5614680B2 |
25-Hydroxycholesterol, an intermediate in the preparation of biologically important metabolites of Vitamin D3 is synthesized in a multi-step process from pregnenolone.
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JPS5614119B2 |
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JPS566439B2 |
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JPS565500A |
Improved yields of 25-hydroxycholesterol are obtained by employing 3 beta -hydroxy-5-cholenic acid as the starting material. This compound is an intermediate for 25-hydroxycholecalciferol.
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JPS55167300A |
NEW MATERIAL:Cynanchogenin glycoside of the formula. USE: An immune enhancing agent. PROCESS: The finely cut and dried root of cynanchum caudatum MAX. of the family Asclepiadaceae is macerated or digested with an organic solvent, e.g. an...
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JPS55164700A |
NEW MATERIAL:The titled compound of formula I (R1-3 are H or OH-protecting group). USE: Intermediate for the preparation of various active vitamin D3. PROCESS: One of the objective compound of formula I wherein R3 is H can be prepared, e...
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JPS5527080B2 |
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JPS5592313A |
A saponine extract product which is a granulate in pellet form, the granules being pourable and having low hygroscopicity. A process for producing a pourable granular saponine extract product of low hygroscopicity comprising granulizing ...
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JPS5526155B2 |
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JPS5523246B2 |
A process for producing amorphous preparations of steryl glucoside monopalmitates, wherein steryl glucoside monopalmitates are heated at a temperature above 110 DEG C up to about 145 DEG C or the compounds are dissolved in an organic sol...
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JPS5521760B2 |
Novel steroids having the general formula:
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JPS5512919B2 |
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JPS555520B2 |
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JPS552439B1 |
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JPS54145649A |
Steroids of the formula wherein represents a single or double bond, X is hydrogen, fluorine or methyl; Y is hydrogen, hydroxy or alkanoyloxy of 1-6 carbon atoms; Z is hydrogen or methyl; V is methylene, ethylidene, hydroxymethylene or vi...
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JPS54130550A |
Cholestane derivs. of formula (I) are new: (where R1 and R2 together form a bond, or R1 is OH and R2 is H; and (a) R3=R4=R5=H, or (b) R3+R4=0 and R5=H, or (c) R3+R5=0 and R4=H, or (d) R3 and R5 together form a bond and R4=H, or (e) R3+R4...
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JPS5429497B2 |
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JPS54101436A |
Anti-inflammatory medicaments comprise a sterol glycoside or ester thereof, and/or a spiroketal-steroid glycoside or ester thereof. Preferred active compounds include glucosides of tall oil sterols, sitosterol, ergosterol, cholesterol, 5...
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JPS5411369B2 |
PURPOSE:An anti-shock agent remarkably effective to rapid and strong shock such as endotoxin shock, anaphylactic shock, etc., containing the title sterylglucose ethers.
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JPS53141259A |
Steroidal acids of the formula (I) are prepared from steroidal ketones of the formula (II) wherein R1 is hydrogen; hydroxy; lower alkyloxy; tetrahydropyranyloxy; aryloxy; alkyl; alkanoyloxy or aroyloxy; R2 is hydrogen; hydroxy; lower alk...
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JPS5320988B2 |
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JPS5320987B2 |
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JPS5320986B2 |
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JPS5320984B2 |
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JPS5365868A |
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JPS5314555B1 |
1282019 19-(Substituted methylene)-cardenolides FARBWERKE HOECHST AG 23 July 1969 [23 July 1968] 37102/69 Heading C2U The invention comprises compounds of formula wherein R 1 is cyano, phenyl, vinyl, methylthio or a group of formula CO 2...
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JPS5314065B2 |
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JPS538768B2 |
Digoxin forms novel complexes with dihydroxybenzenes such as hydroquinone, resorcinol and pyrocatechol. These complexes exhibit rapid dissolution and high solubility in aqueous media. These complexes are useful in the treatment of cardia...
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JPS5329912A |
PURPOSE: To conveniently obtain sterol-glycosides, useful as hemostatics, capillary stabilizer, etc., in high yield by dissolving vegetable material, e. g. soy-bean lecithin, in an org. solvent, followed by precipitation with an alkali c...
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JPS52142056A |
A process for the preparation of steroids of the formula: *** in which R1 is a group -NraRb, in which Ra and Rb (which may be the same or different) are C1-6 alcoholic groups or C3 alkenyl- 6 (provided that Ra and Rb together contain 2-7...
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JPS52108960A |
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JPS52105159A |
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JPS5231871B2 |
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