| Document |
Document Title |
|
WO/2023/141744A1 |
Provided are recombinant Lactococcus lactis, a microcapsule and the use thereof, which belong to the technical field of genetic engineering. A first fusion gene or second fusion gene is inserted into PNZ8149 by means of using PNZ8149 as ...
|
|
WO/2023/142881A1 |
Provided in the present invention is a method for constructing a threonine-producing strain. In the present invention, using a pyruvate quinone dehydrogenase-inactivated strain (Corynebacterium) in the production of threonine can increas...
|
|
WO/2023/142253A1 |
Provided are a polyphosphate kinase mutant, engineering bacteria and a use thereof. The polyphosphate kinase mutant is obtained by a single mutation or a multi-site mutation at position 79, 106, 108, 111 or 285 of the amino acid sequence...
|
|
WO/2023/145850A1 |
Provided are algae having a dark active cryptochrome in which activation is maintained in darkness. Also provided is a method for improving algae growth in darkness, said method comprising introducing, into the algae, a polynucleotide en...
|
|
WO/2023/142855A1 |
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a recombinant microorganism, a method for constructing same and use thereof. According to the present invention, by means of constr...
|
|
WO/2023/142872A1 |
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of corynebacterium genus producing threonine, a method for constructing the same, and use thereof. The act...
|
|
WO/2023/142854A1 |
Provided is a method for constructing a threonine production strain. By means of constructing a corynebacterium having an enhanced transketolase activity, the threonine production capacity of the strain is improved. In combination with e...
|
|
WO/2023/145861A1 |
The present invention is an anti-ubiquitin synthetic antibody including a fibronectin type III polypeptide monobody.
|
|
WO/2023/142499A1 |
The present invention belongs to the field of genetic engineering and grain science. Disclosed is the use of Aspergillus cristatus glucose oxidase in improving the processing quality of flour. In the present invention, recombinant Asperg...
|
|
WO/2023/142162A1 |
Disclosed are a bacillus strain WYJ-E14 isolated from curcuma wenyujin Y. H. Chen & C. Ling and use thereof in the preparation of an anti-tumor drug. An endophyte isolated from a rhizome part of curcuma wenyujin Y. H. Chen & C. Ling belo...
|
|
WO/2023/146967A1 |
The present disclosure provides variant Listeria bacteria that lack functional ribC and ribF genes. Also provided are methods of making and using the variant Listeria bacteria, e.g., as vectors, vaccines, and therapeutics. The present di...
|
|
WO/2023/146387A1 |
The present invention relates to an unregulated Δnrg1 FMA2 U. maydis mutant strain in nrg1 metabolism for producing MEL and UA in the presence of nitrogen. It describes the production of a mixture of glycolipids from the culture of the ...
|
|
WO/2023/145966A1 |
Provided is a method for producing 3-phenylpropionic acid analogue compounds given by formula (I), the production method characteristically comprising a step for culturing a lactic acid bacterium from genus Weissella using a culture medi...
|
|
WO/2023/143387A1 |
Provided are antigen-binding fragments thereof that bind to DXd, and use of the antibody for detection and assay of DXd.
|
|
WO/2023/142871A1 |
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of the corynebacterium genus, a method for constructing same and use thereof. The activity of oxaloacetate...
|
|
WO/2023/147487A1 |
The present disclosure relates generally to high-frequency ultrasonicator devices, and more specifically to high-frequency ultrasonicator devices for disrupting or lysing cells, and methods for using those devices.
|
|
WO/2023/146181A1 |
The present invention provides Chlorella vulgaris H92 (Chlorella vulgaris H92)(KCTC 14843BP) having heme precursor production ability. In addition, the present invention provides a method for preparing a chlorella bacterial body or a foo...
|
|
WO/2023/143136A1 |
Disclosed are a yeast engineering bacterium for fermentative production of α-santalene and use thereof. Yeast is used as an original strain, and by means of the introduction of a gene construct, a yeast engineering bacterium that can ef...
|
|
WO/2023/142879A1 |
The present invention belongs to the field of microbial strains. Disclosed is use of bacillus coagulans in the preparation of a medicament or a food product for mitigating a decline of body functions caused by hyperglycemia and hyperlipi...
|
|
WO/2023/144707A1 |
The present disclosure provides a method for increasing production of a polyunsaturated fatty acid, especially eicosapentaenoic acid (EPA), in a microorganism, comprising adjusting the macro- and/or micronutrients during fermentation. Th...
|
|
WO/2023/144174A1 |
The invention provides Streptococcus thermophilus mutants, such as DSM22933, which have improved texturizing properties. The strains have: (i) a mutation in the branched chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) ...
|
|
WO/2023/142848A1 |
Provided is a promoter, which has a nucleotide sequence shown in SEQ ID NO.1. The promoter is obtained by means of rationally designing a promoter of a dapA gene, has obviously reduced transcriptional activity and can be used for the wea...
|
|
WO/2023/146206A1 |
Provided are a capsule having an oil extract of a Streptococcus infantis strain impregnated therein, a fiber having the capsule attached thereto, bedding or clothing comprising the fiber, and respective manufacturing methods therefor. Ac...
|
|
WO/2023/144351A1 |
The present invention relates to means and methods comprising Paraburkholderia bacteria for use in preventing and/or controlling plant pests, in particular Erwinia amylovora which constitutes the causative agent of fire blight. The prese...
|
|
WO/2023/142899A1 |
The present invention belongs to the technical field of molecular biology and specifically provides a mutant RNase R, a method for preparing same, and use thereof. The provided mutant RNase R is named as RNase R △M8, which has an amino...
|
|
WO/2023/142877A1 |
Provided is the use of Bacteroides fragilis in the improvement and/or treatment of diarrhea. Tests of different mouse diarrhea models prove that Bacteroides fragilis ZY-312 with the deposit number of CGMCC No.10685 or inactivated Bactero...
|
|
WO/2023/142860A1 |
The present invention provides a method for constructing a threonine-producing genetically engineered bacterium. According to the present invention, by means of reducing the activity of 2-formyl-citrate synthase 2 or inactivating the syn...
|
|
WO/2023/144274A1 |
The present invention relates to the field of probiotics, more particularly to the probiotic yeast Saccharomyces boulardii. The present invention provides genetic engineering approaches such as the use of gene deletions and the use of ch...
|
|
WO/2023/143872A2 |
The present invention relates to a method for producing lipids comprising culturing an oleaginous yeast, wherein said oleaginous yeast has been transformed to express lipid-droplet associated protein and/or diacylglycerol acyltransferase.
|
|
WO/2023/142859A1 |
The present invention relates to the technical field of microbial engineering, and in particular to a modified Corynebacterium microorganism, a method for constructing same and use thereof. The present invention provides use of weakening...
|
|
WO/2023/142873A1 |
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of corynebacterium genus, use thereof in producing threonine, and a method for constructing the same. The ...
|
|
WO/2023/142862A1 |
Provided are a recombinant microorganism for producing threonine and the use thereof in the fermentation production of threonine or a derivative thereof. A 20-30 bp fragment upstream of an initiation codon of a gene encoding phosphoenolp...
|
|
WO/2023/142853A1 |
Provided is a method for constructing a genetically engineered bacterium for highly producing threonine. The ability of the strain to produce threonine is improved by means of reducing the activity of the transcriptional regulation facto...
|
|
WO/2023/145833A1 |
Provided is a mutant MAD7 protein demonstrating enhanced breakage activity to a target site. This mutant MAD7 protein contains an amino acid sequence B resulting from mutation of an amino acid sequence A with Sequence Number 1, the amino...
|
|
WO/2023/145859A1 |
The purpose of the present invention is to provide: a novel human-derived monoclonal antibody that binds to a spike (S) protein of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) to neutralize the SARS-CoV-2; an antigen-bi...
|
|
WO/2023/140325A1 |
The present invention provides a DNA cassette primarily comprising: a replication initiation sequence that can bind with an enzyme having DnaA activity; and a first promoter sequence, transcription from the first promoter sequence flowin...
|
|
WO/2023/141576A1 |
Compositions comprising terpene-containing lipidoid compounds, methods of preparing such compositions, and the use of these compositions in gene delivery applications are disclosed.
|
|
WO/2023/140321A1 |
The present disclosure provides a method for producing an improved target organism, the method comprising: (A) a step for selecting an individual showing the improvement from candidate microorganisms of a biological species to which a de...
|
|
WO/2023/137785A1 |
An application of sativene, a recombinant biocontrol fungus, and bombyx batryticatus and an application thereof. Provided is an application of sativene in insect attraction and/or pest control. Sativene is attractive to insects. The high...
|
|
WO/2023/140361A1 |
The purpose of the present invention is to provide a novel transcription factor that acts in yeast. The present invention relates to: a transcription factor comprising (i) the amino acid sequence represented by SEQ ID NO:1 or an amino ac...
|
|
WO/2023/137719A1 |
A miRNA, and a derivative and application thereof. The nucleic acid sequence of the miRNA is as shown in Seq ID No.1 or is a nucleic acid sequence obtained by modifying, substituting, deleting, or adding at least one basic group to the n...
|
|
WO/2023/140348A1 |
The purpose of the present invention is to provide spermatozoa having high motility. The present invention is a composition for spermatozoa treatment that includes a mesenchymal stem cell culture supernatant. The composition for sperma...
|
|
WO/2023/138301A1 |
Provided are a surfactin synthase mutant and the use thereof. The surfactin synthase mutant or fragment thereof comprises an amino acid mutation located in a first functional domain of a first module of the surfactin synthase and on a bi...
|
|
WO/2023/141544A1 |
A method and system is provided for increasing lipids, biomass, and metabolite yields of a microalgae culture of cells and other organisms with conserved metabolic pathways compared to an untreated culture or organism when maintained und...
|
|
WO/2023/141549A2 |
The disclosure relates to isolated microorganisms—including novel strains of the microorganisms, microbial consortia, and agricultural compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the descr...
|
|
WO/2023/137994A1 |
Disclosed in the present invention are a specific nanoantibody Nb3.27 against a colorectal cancer-associated Bacteroides fragilis toxin protein activator, and an application thereof. By means of in-depth research of enterotoxigenic Bacte...
|
|
WO/2023/140347A1 |
The purpose of the present invention is to provide sperm having high motility. The present invention is a composition for sperm treatment that contains medium for mesenchymal stem cells. This composition for sperm treatment is used as ...
|
|
WO/2023/139112A1 |
A method for determining a resistance and/or virulence profile for a plant pathogen in a location. The method comprising receiving a sample of a plant pathogen, subjecting the sample to DNA sequencing, determining the presence of at leas...
|
|
WO/2023/140608A1 |
The present invention relates to the preparation of a recombinant strain to which a gene coding for a recombinant photosynthetic enzyme into which squalene epoxidase and cytochrome P450 reductase are translationally fused, a gene coding ...
|
|
WO/2023/138678A1 |
Provided are Bacillus velezensis, and a composition, a plant growth promoter, a biological culture, and a plant growth substrate comprising Bacillus velezensis, and the present invention further relates to the use thereof. Specifically, ...
|
