Title:
脳神経機能異常検出剤
Document Type and Number:
Japanese Patent JP7134630
Kind Code:
B2
Abstract:
To provide a cranial nerve function abnormality detection agent which can detect cranial nerve function abnormality at an early stage.SOLUTION: Provided is a cranial nerve function abnormality detection agent containing a compound represented by a general formula (1) as an active ingredient and being based on the detection of olfactory nerve mitochondrial complex I (MC-I). [In the general formula (1), R represents -O(CH)-, -O(CH)OCH-, -CHO(CH)-, or -CHO(CH)OCH-; n represents an integer of 1-5; and Qrepresents a label group.]SELECTED DRAWING: None
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Inventors:
Hideo Tsukada
Fumio Hashimoto
Hiroyuki Ohba
Fumio Hashimoto
Hiroyuki Ohba
Application Number:
JP2018008907A
Publication Date:
September 12, 2022
Filing Date:
January 23, 2018
Export Citation:
Assignee:
Hamamatsu Photonics Co., Ltd.
International Classes:
A61K51/04
Domestic Patent References:
| JP2011148793A |
Foreign References:
| WO2014030709A1 |
Other References:
別冊BIO Clinica, 2015, Vol.4, No.2, pp.114-119
J. Neural. Transm., 2010, Vol.117, pp.1337-1351
Neuroscience Letters, 2009, Vol.454, pp.187-192
BIO Clinica, 2018, Vol.33, No.8, pp.37-43
Methods in Enzymology, 2014, Vol.547, pp.417-431,http://dx.doi.org/10.1016/B978-0-12-801415-8.00020-5
J. Nucl. Med., 2016, Vol.57,No.6, pp.950-953,DOI: 10.2967/jnumed.115.169615
J. Neural. Transm., 2010, Vol.117, pp.1337-1351
Neuroscience Letters, 2009, Vol.454, pp.187-192
BIO Clinica, 2018, Vol.33, No.8, pp.37-43
Methods in Enzymology, 2014, Vol.547, pp.417-431,http://dx.doi.org/10.1016/B978-0-12-801415-8.00020-5
J. Nucl. Med., 2016, Vol.57,No.6, pp.950-953,DOI: 10.2967/jnumed.115.169615
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshiki Kuroki
Kenichi Shibayama
Toshiaki Sakanishi
Yoshiki Kuroki
Kenichi Shibayama
Toshiaki Sakanishi