Title:
COMPOSITION, FOR PREVENTING, TREATING OR RELIEVING INFLUENZA VIRUS INFECTION, COMPRISING MIXTURE OF AGRIMONIA PILOSA EXTRACT AND GALLA RHOIS EXTRACT AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2023/038480
Kind Code:
A1
Abstract:
The present invention relates to a composition, for preventing, treating or relieving influenza virus infection, comprising a mixture of an Agrimonia pilosa extract and a Galla rhois extract as an active ingredient, and does not cause side effects to a human body and thus exhibits excellent safety, and also has excellent antiviral activity due to a cell lesion effect through a virus-dependent pathway, an influenza virus-related gene reducing effect, and the like. Further, the present invention not only is confirmed with an in vivo antiviral effect but also has notably excellent antiviral activity in the active ingredient of the mixed extracts, and thus may be utilized for a composition for preventing, treating or relieving influenza virus infection.
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Inventors:
KANG SE CHAN (KR)
SEO YOUNG-JIN (KR)
KIM HYUNGGUN (KR)
LEE YEONG-GEUN (KR)
CHOI SOON HO (KR)
SEO YOUNG-JIN (KR)
KIM HYUNGGUN (KR)
LEE YEONG-GEUN (KR)
CHOI SOON HO (KR)
Application Number:
PCT/KR2022/013577
Publication Date:
March 16, 2023
Filing Date:
September 08, 2022
Export Citation:
Assignee:
APRG INC (KR)
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
UNIV CHUNG ANG IND ACAD COOP FOUND (KR)
RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR)
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
UNIV CHUNG ANG IND ACAD COOP FOUND (KR)
RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR)
International Classes:
A61K36/73; A23L33/105; A61K31/19; A61K31/352; A61K31/7034; A61K36/22; A61P31/16
Foreign References:
| CN101361792A | 2009-02-11 | |||
| KR20200130177A | 2020-11-18 | |||
| KR20120118707A | 2012-10-29 |
Other References:
KWON JEONG EUN; LEE YEONG-GEUN; KANG JI-HUN; BAI YUN-FENG; JEONG YONG JOON; BAEK NAM-IN; SEO YOUNG-JIN; KANG SE CHAN: "Anti-viral activity of compounds from Agrimonia pilosa and Galla rhois extract mixture", BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC., NEW YORK, NY., US, vol. 93, 26 September 2019 (2019-09-26), US , XP085903703, ISSN: 0045-2068, DOI: 10.1016/j.bioorg.2019.103320
LEE YEONG-GEUN, KANG KYUNG WON, HONG WOOJAE, KIM YEON HWA, OH JEN TAEK, PARK DAE WON, KO MINSUNG, BAI YUN-FENG, SEO YOUNG-JIN, LEE: "Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 45, 1 September 2021 (2021-09-01), AMSTERDAM, NL, pages 116329, XP093028750, ISSN: 0968-0896, DOI: 10.1016/j.bmc.2021.116329
LEE YEONG-GEUN, KANG KYUNG WON, HONG WOOJAE, KIM YEON HWA, OH JEN TAEK, PARK DAE WON, KO MINSUNG, BAI YUN-FENG, SEO YOUNG-JIN, LEE: "Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 45, 1 September 2021 (2021-09-01), AMSTERDAM, NL, pages 116329, XP093028750, ISSN: 0968-0896, DOI: 10.1016/j.bmc.2021.116329
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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