Title:
METHOD FOR TREATING BRONCHIAL CONSTRICTION AND BRONCHOSPASM
Document Type and Number:
WIPO Patent Application WO2003017929
Kind Code:
A3
Abstract:
The present invention is directed to a method for treating bronchial constriction in mammals. The method comprises contacting mammalian lung with a compound selected from the group consisting of pyruvate and pyruvate precursors. The compound is present in a therapeutically effective amount to produce bronchial dilation. The present invention is also directed to a method for treating airway disease in mammals. The method comprises contacting mammalian lung with a compound selected from the group consisting of pyruvate and pyruvate precursors. The compound is present in an amount from about 0.0001 millimoles to about 0.005 millimoles. The present invention is further directed to a method for treating airway disease in mammals. The method comprises contacting the mammalian lung with a compound selected from the group consisting of pyruvate and pyruvate precursors. The compound is present in a therapeutically effective amount to prevent bronchial spasm. The present invention is still further directed to a method for treating airway disease in mammals. The method comprises contacting the mammalian lung with a compound selected from the group consisting of pyruvate and pyruvate precursors. The compound is present in a therapeutically effective amount to prevent bronchial constriction.
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Inventors:
KATZ STANLEY E (US)
Application Number:
PCT/US2002/026059
Publication Date:
May 08, 2003
Filing Date:
August 15, 2002
Export Citation:
Assignee:
CELLULAR SCIENCES INC (US)
KATZ STANLEY E (US)
KATZ STANLEY E (US)
International Classes:
A61P11/08; A61K9/12; A61K9/14; A61K31/135; A61K31/19; A61K31/20; A61K31/22; (IPC1-7): A61K31/19; A61K31/20; A61K31/22
Foreign References:
| US5714515A | 1998-02-03 | |||
| US6051609A | 2000-04-18 | |||
| US5952384A | 1999-09-14 |
Other References:
See also references of EP 1429712A4
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