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WO/2019/227177A1 |
The invention relates generally to sorbents and sorption devices for extracting compounds. The invention relates to a sorbent comprising a polymer and microdiamond. The invention also relates to a sorption device comprising the sorbent. ...
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WO/2019/229673A1 |
The present disclosure relates to methodologies, systems, apparatus, and kits for controlling fluid flow within a chromatography system. A makeup pump is configured to pump a makeup fluid into the chromatography system downstream of the ...
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WO/2019/227231A1 |
A chromatography valve for use in fluid analysis and chromatography applications is provided. The valve includes a first body having passages extending therethrough and opening on a flat face of the first body at respective passage ports...
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WO/2019/229055A1 |
The present invention relates to a method for detecting at least one oligonucleotide conjugate of interest in solution, wherein the oligonucleotide conjugate of interest is composed of a nucleic acid entity and of a nonpolar entity, wher...
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WO/2019/229697A1 |
The disclosure relates to a recycling chromatography method that includes injecting a sample into a mobile phase flow stream of a chromatography system to create a combined flow stream. The sample includes an API and at least one impurit...
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WO/2019/229676A1 |
The present disclosure relates to methodologies, systems, apparatus, and kits for introducing a sample within a chromatography system. A makeup pump is configured to pump a makeup fluid through a first restrictor into the chromatography ...
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WO/2019/226588A1 |
Disclosed herein are compositions, devices, and methods for isolating human Adipose-derived stem cells (ASCs) without either electricity or enzymatic digestion. In particular, a paramagnetic immunobead (PIB) for isolating human ASCs is d...
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WO/2019/224201A1 |
The present invention relates to a method of conditioning a dry-packed chromatography column, which method comprises providing a column packed with inert and hydrophilic chromatography resin; and driving a solvent or solvent mix across t...
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WO/2019/224775A1 |
The present invention concerns an extracorporeal circuit (1, 100, 200, 300, 400, 500) for removing CO2 from blood comprising a blood withdrawal line (2) for withdrawing blood from the patient, a filtration unit (6) for producing plasma w...
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WO/2019/224702A2 |
Sample preparation and separation can be performed using a sample cartridge. The cartridge incudes a barrel with a first and second end, a column segment connected to the second end of the barrel, and a column containing a sorbent materi...
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WO/2019/220866A1 |
The present invention relates to a method for producing porous cellulose beads which comprises dispersing a phase, which is to be a dispersed phase and comprises either cellulose or a cellulose derivative, in a highly safe, continuous ph...
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WO/2019/220001A1 |
A method of recovering radiochemically clean boron from aqueous liquid radioactive waste which contains radionuclides and boron. The method comprises contacting the liquid waste with at least one ion exchange material (5a, 5b, 6a, 6b, 7a...
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WO/2019/213753A1 |
The present disclosure provides a process for polishing at least one metal contaminant from a stock solution comprising Sc comprising the steps of a) contacting the stock solution with an ion exchange resin capturing Sc and the at least ...
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WO/2019/211930A1 |
An autosampler that: has a sampling flow path for temporarily holding a sample; is selectively switched between an injecting mode in which the sampling flow path is incorporated into an analysis flow path for a liquid chromatograph and a...
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WO/2019/212881A1 |
Embodiments of the present disclosure include methods and systems for detecting the presence of endotoxins in filters. For example, embodiments of the present disclosure are directed to methods and systems for improving in-process contro...
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WO/2019/206841A1 |
The invention relates to a method for purifying a mixture to be separated containing fructose, in a multi-column chromatography system, said method successively comprising, in a cyclical manner: a step of collecting a raffinate, a step o...
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WO/2019/206842A1 |
The invention concerns a method for purifying a mixture to be separated, in a multi-column chromatographic system, the method comprising successively, in a cyclic manner: - a step of collecting a refinement, a step of injecting the mixtu...
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WO/2019/206843A1 |
The invention relates to a method for producing a fructose composition comprising the following successive steps: - providing an initial composition comprising glucose; - concentrating the initial composition by evaporation of water in o...
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WO/2019/204508A1 |
The present disclosure relates to the detection of analytes in high volumetric flow applications. Particular embodiments relate to the use of fluorescence polarization/anisotropy based for detection of analytes in a flow cell. In one tes...
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WO/2019/201465A1 |
The present invention relates to a method for separating one or more components from a liquid feed mixture in an EBA-SMB operating mode without the need of pumps at the outlets of the EBA columns. The present invention also relates to a ...
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WO/2019/200166A1 |
The present disclosure provides "all-in-one" cartridges which contain necessary reagents and materials to isolate/preconcentrate targeted proteins from blood plasma and ionize them for mass spectrometry detection. In another configuratio...
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WO/2019/197760A1 |
The invention relates to a method for purifying proteins comprising a purification step that uses centrifugal partition chromatography, referred to as CPC, from a microalgae extract dispersed in a mixture comprising an aqueous two-phase ...
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WO/2019/192877A1 |
A bind/elute chromatography method and compositions for low salt/low solution conductivity separation of target proteins from a mixture of aggregates and other impurities.
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WO/2019/193579A1 |
This invention relates to the manufacture of a solidifier for crude oil and vegetable oils that can coagulate same irrespective of the viscosity thereof provided that the density of said oils is less than that of water, adsorb the gases ...
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WO/2019/195214A1 |
A urea reagent exhaust treatment fluid configured for use in treating an exhaust produced by an internal combustion engine comprising water, an amount of urea that is about 32.5 wt%, and an amount of biuret that is at most 0.09 wt%, and ...
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WO/2019/195740A1 |
Disclosed are processes for preparation of a carbon foam material, the process comprising heating in a microwave heating apparatus a mixture comprising a coal material and a flux agent. The disclosed processes can comprise heating in a m...
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WO/2019/192059A1 |
A functionalized high-density chromatographic substrate, a preparation method therefor, and an application thereof. The chromatographic substrate functionalization method employs a hydrophilic microsphere having a polyhydroxy structure o...
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WO/2019/193300A1 |
The invention relates to a method for controlling preparative liquid chromatography, comprising the following steps, at least some of said steps being implemented by a computer comprising a processor and a display screen that is coupled ...
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WO/2019/194935A1 |
Apparatus and method for packing a chromatography column. The apparatus is a rack that may support and/or transport one or more containers of the same or different sizes. The one or more containers and their contents may be agitated in t...
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WO/2019/195745A1 |
Processes are disclosed for preparation of a carbon foam material, the process comprising devolatization of coal-derived pitches or extracts at atmospheric pressure near green coke temperatures, thereby forming a solid coke-like material...
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WO/2019/189422A1 |
A method for separating steviol glycoside(s), said method involving separation step 55 for performing continuous liquid chromatography wherein a liquid to be separated, which contains multiple kinds of steviol glycosides, is passed throu...
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WO/2019/186382A1 |
A system and a method for collecting waste in chromatography is provided. The system includes a base unit comprising a housing, wherein the housing comprises a plurality of openings, wherein the plurality of openings is configured to rec...
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WO/2019/190092A1 |
The present invention relates to a Bordetella pertussis-derived protein-obtaining method including an affinity chromatography process. The present invention increases the production yield of PT and FHA proteins by isolating PT and FHA pr...
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WO/2019/186579A1 |
Method of making a concentrate composition comprises heat stable proteins from juice of a plant part by subjecting the juice to heat treatment to precipitate heat precipitable/coagulable phytochemicals leaving behind Juice Solubles, and ...
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WO/2019/191133A1 |
Disclosed herein are methods of controlling, modulating, increasing, or improving protein yield in a sample mixture comprising a target protein and impurities comprising monitoring in real-time an ultraviolet (UV) signal of the sample mi...
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WO/2019/187377A1 |
This base material for a filler comprises a natural polymer immobilized on the surface of a porous organic polymer carrier, the porous organic polymer carrier has a crosslinking degree of 50-85 mol%, the exclusion limit molecular weight ...
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WO/2019/187603A1 |
A purpose of the present invention is to provide a peptide that has a high chemical stability to alkalis, etc. Another purpose of the present invention is to provide: a DNA encoding the aforesaid peptide; a vector containing the DNA; and...
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WO/2019/191192A1 |
A thermal pad for promoting heat transfer between a column heating module and a mobile phase of a liquid chromatography system includes is provided. The thermal pad includes a silicone layer, the silicone layer having a reinforcement sti...
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WO/2019/189064A1 |
In a method for producing a protein from animal cells, clogging of a column or filter closely packed in an airtight container makes continuous operation difficult. To solve this problem, provided is a module wherein: a slurry containing ...
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WO/2019/186469A1 |
The technology relates to a recycling chromatography method. A sampled is injected into a mobile phase flow stream of a liquid chromatography system creating a combined flow stream. The liquid chromatography system includes at least two ...
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WO/2019/187585A1 |
The purpose of the present invention is to provide a method for packing a carrier into a large column by supply of a slurry, wherein the method reliably produces a packed bed that makes it possible to reproducibly obtain a favorable chro...
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WO/2019/190046A1 |
The present invention relates to a method for concentrating a pathogen using diatoms and cucurbiturils. According to the present invention, a diatom-cucurbituril composite, which is prepared by modifying the surface of diatoms with a sil...
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WO/2019/189335A1 |
The present invention provides a device and method for performing treatment of a liquid such as a nucleic acid-containing sample liquid by a liquid-permeable carrier under stable conditions. This liquid passage device 1 is for passing a ...
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WO/2019/189807A1 |
The purpose of the present invention is to provide a method for packing a carrier into a large column by supply of a slurry, wherein the method reliably produces a packed bed that makes it possible to reproducibly obtain a favorable chro...
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WO/2019/178587A1 |
The present invention provides a method of purifying a target molecule in a sample containing the target molecule, for example, an acidic target molecule, that utilizes a multimodal ligand.
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WO/2019/178495A1 |
The present disclosure describes methods for purifying recombinant adenoassociated viruses (AAVs). Specifically, the methods involve separating AAV particles that include a nucleic acid payload (full AAV particles) and AAV particles that...
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WO/2019/175849A1 |
The present disclosure concerns the development of a novel stationary phase for the separation of nucleic acids in the context of preparative chromatography, using a chromatographic matrix, preferably a macroporous matrix, particularly a...
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WO/2019/172836A1 |
A protein-binding product comprising one or more porous polymer beads, wherein at least one ligand is bound to the surfaces of said polymer beads via a spacer (R), and wherein said at least one ligand is Galβ1-3Hex NAcβ-O-, Galβ1-4Glc...
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WO/2019/173731A1 |
Chromatography resins having anionic exchange-hydrophobic mixed mode ligands, that are useful for purifying target biomolecules using anionic exchange (i.e., where the ligand is positively charged) and hydrophobic mixed mode chromatograp...
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WO/2019/170635A1 |
The present invention relates to composite materials useful for purifying proteins obtained from biological feedstocks. The composite materials of the invention comprise a porous support having an average pore size of 5 to 500 nm, said p...
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