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WO/2018/229271A1 |
The present invention relates to an apparatus, a method, a computer program and a computer program product for determining one or more buffer composition recipes. The method comprising obtaining design of experiment, DoE, data, wherein t...
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WO/2018/225557A1 |
This extracellular polysaccharide of lactic acid bacteria, which are derived from fig and belong to Lactobacillus paracasei, is useful for foods and drinks, medicines, fodders, cosmetics, etc., which exhibit anti-allergic effect and the ...
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WO/2018/182932A9 |
The invention concerns an installation for treatment of biological liquid by chromatography, extending in a longitudinal direction and comprising a supply valve (20b), a supply pump (30) downstream of the valve, instrument members downst...
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WO/2018/220982A1 |
Provided is a method for treating nonionic surfactant-containing water, the method comprising an adsorption step for passing nonionic surfactant-containing water as supplied water through a microfiltration membrane or ultrafiltration mem...
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WO/2018/222972A1 |
The present invention relates to a method and/or device for improving the separation behaviors and performance of aqueous two-phase system (ATPS) for the isolation and/or concentration of one or more target analytes from a sample. In one...
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WO/2018/222593A1 |
Calibrants and methods of making the same include using mixtures of multifunctional core compounds or multifunctional dendrimers that are functionalized to yield a set of discrete compounds which cover a range of collisional cross sectio...
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WO/2018/217629A1 |
The present invention concerns methods of treating a patient suffering from a traumatic brain injury (TBI), comprising contacting said patient's blood with a sorbent for an inflammatory mediator and kits for performing such treatments.
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WO/2018/218254A1 |
A device and system for conducting accurate diagnosis of states of disease or health, including cancer, with high sensitivity and specificity is described. The system employs a portable cassette-based testing system which is configured t...
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WO/2018/212556A1 |
The present disclosure relates to a method for separating and purifying an antibody or an antibody fragment thereof in high purity using affinity chromatography, and specifically, to a method for separating the antibody and antibody frag...
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WO/2018/212165A1 |
The present invention addresses the problem of providing a column tube for chromatography with which it is possible to prevent a peak shape abnormality known as a fit in a resulting chromatogram. This problem is resolved by means of a co...
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WO/2018/210818A1 |
The invention relates to a gas-liquid separator for a chromatography plant, comprising: a) a separating region having an inlet nozzle, a baffle unit and a gas distribution unit; b) a dividing region having a liquid outlet and c) a gas ou...
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WO/2018/208447A1 |
Methods of maintaining narrow residence time distributions in continuous flow systems, particularly applicable to virus inactivation such as during a protein purification process. Fluid sample is introduced into an axial flow channel and...
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WO/2018/208489A1 |
An apparatus is described for controlling fluid flow and in particular fluid flow through a microfluidic multi-port control valve assembly of a High Pressure Liquid Chromatography (HPLC) unit. The flow control apparatus has a localized d...
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WO/2018/208448A1 |
Methods of maintaining narrow residence time distributions in continuous flow systems, particularly applicable to virus inactivation such as during a protein purification process. Fluid sample is introduced into an axial flow channel and...
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WO/2018/204069A1 |
Methods of regenerating a strong base anion resin are described. The method comprises collecting a salt-containing product from a chromatographic system configured to process a biomass derived material. The salt-containing product is pro...
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WO/2018/203231A1 |
The present disclosure relates generally to a system of method development in a highly-compressible fluid based chromatography system. In particular, the disclosure relates to method development in a carbon dioxide based chromatography s...
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WO/2018/203541A1 |
The present invention is characterized by providing a treatment method for recovering and purifying polypeptides having immunoglobulin binding activity using a genetically modified organism, wherein, rather than relying on differences in...
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WO/2018/204897A1 |
An RF driver provides power to an acoustic transducer, which can be implemented as a piezoelectric element, which presents a reactive load. The driver can be a linear amplifier or a combination of a DC-DC converter and DC-AC inverter. A ...
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WO/2018/203230A1 |
The present disclosure relates generally to a system and a method for improving performance of a chromatography system using a highly-compressible fluid based mobile phase (e.g., CO2). In particular, the present disclosure relates to a s...
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WO/2018/198817A1 |
The present invention addresses the problem of providing FcRn having improved stability with respect to heat and acids, a method for producing said FcRn, an antibody adsorbent in which said FcRn is used, and an antibody isolation method ...
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WO/2018/201041A2 |
Adsorbers have many purposes in chemical, gas-processing, and petrochemical plants. Adsorbers may be used to remove components from gas streams. Adsorbers may be subjected to various issues, including but not limited to moisture breakthr...
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WO/2018/197789A1 |
The invention relates to a process for preparing a monolithic stationary phase, which comprises the preparation of a polymerizable composition and the polymerization thereof. According to the invention, the polymerizable composition comp...
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WO/2018/200619A1 |
A collection of resin particles is provided, wherein the resin particles comprise one or more polymers; wherein the polymer comprises methylene bridge groups between aromatic rings; wherein the polymer comprises a total amount of amino g...
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WO/2018/197294A1 |
The present invention relates to a method for separating metal ions from a liquid, which method comprises contacting liquid comprising metal ions with non-functionalized cellulose, adsorbing the metal ions to the cellulose, and separatin...
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WO/2018/200290A1 |
The present invention provides a method for purifying Chondroitinase ABC (ChABC). The present method includes using a heparin-immobilized affinity chromatography column, and through chromatography method obtaining a purified ChABC from a...
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WO/2018/200624A1 |
Provided is a collection of resin particles, wherein the resin particles comprise one or more polymers; wherein the polymer comprises methylene bridge groups between aromatic rings; wherein the polymer comprises a total amount of amino g...
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WO/2018/193313A1 |
The invention is directed to utilization of a series of cross-linked 1,4-benzenediamine- co-alkyldiamine polymers and the use of the polymers to remove mercury from a hydrocarbon in fluid form.
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WO/2018/194330A1 |
The present invention relates to an SMB-based fucose separation method and an apparatus therefor and, more particularly, to a method and an apparatus for continuously separating fucose from a microalgae-derived monosaccharide mixture or ...
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WO/2018/193334A1 |
Methods for transferring a separation procedure from a first chromatographic system to a second one are disclosed that involve substantially matching a pressure profile. In some such methods, a length, an area, and a particle size of a f...
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WO/2018/190677A2 |
The present disclosure relates to a method for separating impurities of analogous antibodies using cation-exchange chromatography, and more specifically, to a method for separating the single fragments and isoforms of analogous antibodie...
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WO/2018/191052A1 |
Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet fro...
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WO/2018/191053A1 |
Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet fro...
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WO/2018/189654A1 |
Methods for transferring a carbon dioxide based separation procedure from a reference chromatographic system to a target chromatographic system involve alternative techniques for determining system pressure drops not attributable to the ...
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WO/2018/185501A1 |
There is described a method of making an adsorbent material comprising mixing first particulate material with a second material, homogenising the mixture of the first and second materials, incorporating an impregnating or coating materia...
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WO/2018/184713A1 |
A device for the selective fractionation of ultrafine particles, comprising through-flowable separating columns (3) fluidically connected in series by connecting lines (1), in each case at least two alternately operated inlets (6, 7) for...
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WO/2018/186222A1 |
The present invention addresses the problem of providing porous cellulose beads with little nonspecific adsorption having pore characteristics that achieve a good transmission observation image and a high adsorption level by a simple met...
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WO/2018/186210A1 |
The purpose of the present invention is to provide: a porous fiber that exhibits both improved adsorption capacity, and suppressed exposure and detachment of particulates; an adsorption column filled with said porous fiber; and a blood p...
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WO/2018/184120A1 |
A method of binding a target metal in solution. The method of binding a target metal comprises contacting a solution containing i) a target metal with ii) an encapsulated exudate of a culture of algal flagellate, or a fraction thereof; o...
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WO/2018/180204A1 |
The purpose of the present invention is to provide: a novel modified protein G which is capable of binding to immunoglobulin and shows a high chemical stability against an alkali solution; an affinity separation matrix comprising the mod...
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WO/2018/181925A1 |
The present invention relates to a separating material for gel filtration, the material comprising: porous polymer particles; and a covering layer that includes a polymer having a hydroxyl group, and that covers at least a part of the po...
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WO/2018/181738A1 |
Disclosed is a separation material provided with hydrophobic polymer particles and a coating layer that coats at least a portion of the surfaces of the hydrophobic polymer particles. The coating layer contains a hydrophilic polymer havin...
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WO/2018/183244A1 |
A plurality of collection surfaces for use in an aqueous slurry has a polymeric coating to provide a compliant and sticky surface. The polymer coating has a chemical to render the surface hydrophobic so as to attract hydrophobic or hydro...
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WO/2018/178376A1 |
A method and a kit for cell culture clarification, as well as a system or apparatus for clarifying a cell culture and purifying biomolecules of interest, are described. The cell culture comprises at least one biomolecule of interest. The...
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WO/2018/183164A1 |
This invention uses a fixed-bed adsorber, interchangeably called a capacitor herein, to process the product stream coming out of a regenerable adsorption system such as a temperature swing adsorption system (TSA) or pressure swing adsorp...
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WO/2018/182931A1 |
The invention concerns an installation for treating biological liquid by chromatography, extending in a longitudinal direction and comprising a supply valve (20b), a supply pump (30) downstream of the valve, instrument members downstream...
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WO/2018/178337A1 |
A distributor (100) is described for distributing a fluid flow from a smaller to a more broad fluid flow. It comprises a fluid input (110) and a plurality of fluid outputs (120), and a channel structure in between the fluid input (110) a...
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WO/2018/180205A1 |
The purpose of the present invention is to provide: a novel affinity dissociation matrix which has bindability to an immunoglobulin and has excellent chemical stability toward an alkaline solution; and a method for producing an immunoglo...
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WO/2018/183072A1 |
This invention discloses methods for reducing physiologic molecules in abnormal levels and/or exogenous toxins in blood from blood by way of an extracorporeal circuit comprising a hollow-fiber filter module and polymer sorbent in combina...
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WO/2018/183483A1 |
A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to pro...
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WO/2018/174117A1 |
The present invention addresses the problem of providing a coating liquid for forming an organic film in which an organic compound is finely dispersed, an organic film obtained by coating the coating liquid, and an organic electronic dev...
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