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WO/2004/005229A1 |
The present invention provides compounds of the formula wherein A is of the formula and X, Y, n, R1-R25 are as described in the specification which are modulators of the glucocorticoid receptor and are thus useful for the treatment of an...
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WO/2004/002947A1 |
Compounds of formula (I), wherein R01 is hydrogen, C1-C8alkyl, C3-C8alkenyl or C3-C8alkynyl; or R01 is phenyl or phenyl-C1-C6alkyl, it being possible for the phenyl rings in turn to be mono- to penta-substituted by halogen and/or mono-, ...
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WO/2004/000302A1 |
This invention relates to novel resveratrol analogs of the formula given below; wherein R, R¿1?, R¿2? and R¿3? are: 1. R=OH, R¿1?=R¿2?=R¿3?=H; 2. R=0H, R¿1?=Br, R¿2?=R¿3?=H; 3. R=R¿1?=0H, R¿2?=R¿3?=H; 4. R=R¿1?=R¿3?=H, R¿2...
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WO/2004/000857A1 |
Under pressure, hydrogen gas is brought into contact with an organic compound capable of forming a hydrogen molecule compound, such as a hydrogen inclusion compound, in combination with hydrogen. Hydrogen can be stored stably in a relati...
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WO/2003/104194A1 |
The invention concerns a method for method for preparing 1,3,5-triaminobenzene, characterized in that it comprises a step which consists in amination of a compound of formula (I), wherein: A represents a halogen atom or a NH2 group; X1 a...
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WO/2003/101927A1 |
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially A...
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WO/2003/101916A1 |
A method in which a halide having a substituent group with an acidic proton and having a carbon-carbon double bond in which the carbon atoms have one or more halogen atoms as substituents is subjected to a halogen-metal exchange reaction...
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WO/2003/099750A1 |
The invention relates to organic synthesis, more specifically to a method for producing dihydroxybenzenes by catalytic oxidation of phenol with the aid of nitrogen monoxide in the presence of benzene. The reaction is carried out in a flo...
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WO/2003/095405A1 |
A guest-host assembly having a generally spheroidal host assembly formed of trimers of calixarene molecules in a hexagonal close-packed assembly and its preparation. The calixarene trimers are associated together predominantly by van der...
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WO/2003/093212A1 |
A process for producing a (fluoroalkyl)benzene derivative which comprises: a step in which the total content of transition metals in Groups 3 to 12 in an alkylbenzene derivative is regulated to 500 ppm or lower in terms of the amount of ...
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WO/2003/084909A1 |
The present invention relates to a process for preparing phenols by adding an aqueous base to the reaction product from the acid-catalyzed cleavage of alkylaryl hydroperoxides while maintaining a homogeneous phase prior to the work-up of...
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WO/2003/084910A1 |
A process for converting carbonyl-type impurities contained in a phenolic solvent to high-boiling derivatives is provided by contacting the phenolic solvent with a hydrotalcite-type material (HTM). The phenol can be separated from the hi...
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WO/2003/082785A1 |
A process for production of bisphenol A which comprises subjecting a phenolic slurry (1) of bisphenol A wherein an adduct of bisphenol A with phenol is contained in a crystalline state to filtration to form a layer of the crystalline add...
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WO/2003/082787A1 |
Compounds of Formula (IA) and Formula (IB) wherein R1, R2, R3, R4, R5, and R6 are as defined herein for Formula (IA) or Formula (IB), or a tautomer, prodrug, solvate,or salt thereof; pharmaceutical compositions containing such compounds,...
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WO/2003/077894A1 |
The present invention relates to the synthesis of fluorinated forms of alkyl phenol compounds and their subsequent use as pharmaceutical agents. More specifically, alkyl phenol compounds are fluorinated to increase compound volatility su...
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WO/2003/076378A1 |
A process for producing crystals of a solid adduct of bisphenol A with phenol and/or substantially pure crystals of bisphenol A. The process is characterized in that phenol is reacted with acetone in the presence of a catalyst and two or...
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WO/2003/076376A2 |
This invention refers to a process for the synthesis of phenol and acetone starting from cumene hydroperoxide, and to a plant specifically developed for performing this process. More in particular, this invention refers to a process for ...
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WO/2003/076377A1 |
A process for separating sulfonic acid compounds from a phenolic solvent is provided by contacting the phenolic solvent with a hydrotalcite−type material (HTM). The process can be applied in the conventional industrial process for conv...
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WO/2003/074457A1 |
A method for producing bisphenol includes introducing a phenol and a ketone into a fixed, supported catalytic bed (14) reactor (10) system (50) in a downflow mode, reacting the phenol and the ketone to form a reaction mixture, and recove...
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WO/2003/070675A2 |
This invention provides a compound, or its possible salt, having the formula, wherein: Re and 'Re are OH, optionally independently etherified or esterified&semi Z is −CH2CH2− or −C(R4,R5)− , wherein R4 and R5 are independently H,...
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WO/2003/068713A1 |
The invention relates to a method for production of a liquid composition of an ortho-dihydroxybenzyl compound of high purity and said composition. More particularly The invention relates to the production of a liquid composition of pyroc...
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WO/2003/066555A1 |
The specification provides a method for producing p-cumylphenol phenol by reacting phenol with &agr -methylstyrene in the presence of a highly efficient heterogeneous aluminum zirconium catalyst.
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WO/2003/066554A1 |
The goal of this invention is to produce phenol of high purity by conversion of impurities that are present in the starting phenol, which is produced by the decomposition of cumyl hydroperoxide. The indicated goal is achieved by purifyin...
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WO/2003/064359A1 |
The present invention relates to non-classical cannabinoids that are ligands of the peripheral cannabinoid receptor CB2, and to pharmaceutical compositions thereof comprising as an active ingredient novel (+) α-pinene derivatives, which...
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WO/2003/064501A1 |
There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic polymers and oligomers, of a type having ...
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WO/2003/064358A1 |
Fluorenone is condensed with a phenol [e.g., 2−(C1−4 alkyl)phenol] in the presence of both of a thiol and an aqueous hydrochloric acid solution to produce a fluorene derivative &lcub e.g., 9,9−bis[(C1−4 alkyl)hydroxyphenyl]fluore...
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WO/2003/063758A2 |
The present invention relates to non−classical cannabinoids that are ligands of the peripheral cannabinoid receptor CB2, and to pharmaceutical compositions thereof comprising as an active ingredient novel (&plus ) &agr −pinene deriva...
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WO/2003/062443A2 |
The present invention includes compounds, methods of making the compounds, compositions including the compounds and/or use of the compounds and compositions, wherein the compounds of the following formulas: (I) or (II) or (III).
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WO/2003/062143A1 |
The present invention relates to a non-hazardous brominating reagent from an aqueous alkaline bromine byproduct solution obtained from bromine recovery plant and containing 25 to 35 % bromine dissolved in aqueous lime or sodium hydroxide...
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WO/2003/055601A1 |
A catalyst for bisphenol compound production which has high activity and has resistance to heavy ingredients and alcohols; and a process for producing a bisphenol compound with the catalyst. The catalyst is obtained by modifying a sulfon...
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WO/2003/055849A1 |
The invention relates to a method for the production of solutions a quaternary cation and an anion from a deprotonated hydroxy aromatic in an organic solvent by a reactive extraction of a quaternary salt in the presence of an aqueous hyd...
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WO/2003/053897A1 |
Non−halogenated hydroxyalkyl− substituted phenol compounds, compositions containing the same, and method of using the same for reducing the presence of microorganism on a substrate or in a fluid environment comprising an antimicrobia...
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WO/2003/051804A1 |
A compound represented by the following formula (1) or a salt thereof, which have excellent antitumor activity and excellent angiogenesis inhibitory activity under low-oxygen conditions; and a medicine, such as an antitumor agent or anti...
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WO/2003/051841A2 |
Carbamates and related compounds of formula R1 R2NCO-Y or R1 R2NCS-Y wherein R1 and R2 are hydrogen, alkyl, aryl, heteroaryl or may together form a piperidine, piperazine, morpholine or other heterocyclic ring, are inhibitors of hormone ...
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WO/2003/051842A2 |
Carbamates and related compounds of formula R1R2NCO-Y or R1R2NCS-Y wherein R1 and R2 may form a ring, are inhibitors of hormone sensitive lipase and are useful for the treatment of any disorder where it is desirable to modulate the plasm...
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WO/2003/051805A2 |
This invention provides estrogen receptor modulators of formula (I), having the structure (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10, are as defined in the specification, or a pharmaceutically acceptable salt thereof.
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WO/2003/050066A1 |
This invention is directed to functionalized higher diamondoids having at least one functional group. These derivatives have a higher diamondoid nucleus and up to six independently selected functional groups. The functionalized higher di...
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WO/2003/048094A1 |
A system for purifying a cumene hydroperoxide cleavage product mixture comprises a cumene hydroperoxide cleavage product mixture feed (16) containing impurities in fluid communication with an aqueous alkaline solution feed (18); the cume...
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WO/2003/045883A1 |
A process for making a compound of Formula (I) by oxidative coupling of a compound of the formula (II) in the presence of a molecular oxygen-containing gas and a copper-containing catalyst produced by contacting a copper halide salt with...
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WO/2003/045882A1 |
A system for purifying a cumene hydroperoxide cleavage product mixture comprises a cumene hydroperoxide cleavage product mixture feed (16) containing impurities in fluid communication with an aqueous alkaline solution feed (18); the cume...
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WO/2003/045885A1 |
The compositions 3-alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthol and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphth
ol are disclosed, as well as various processes for making them, all involving the alkylation of 5...
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WO/2003/045884A1 |
A process for making a compound of the formula (I).
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WO/2003/043960A2 |
A purification method is disclosed for a predetermined water-insoluble extractant present in a liquid phase composition that additionally contains one or more additional extractants, synthesis reaction starting materials, and reaction by...
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WO/2003/043965A1 |
The invention relates to a method for producing o-alkylphenols by reacting phenol with an alkanol at an elevated temperature in the gaseous phase and in the presence of a metal oxide catalyst, whereby the reaction is carried out in at le...
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WO/2003/042146A1 |
A process is described for preparing hydroxylated aromatic compounds by means of the direct oxidation of an aromatic substrate with hydrogen peroxide in a triphasic reaction system, in the presence of a TS-1 zeolitic catalyst.
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WO/2003/040382A1 |
A process for easily producing from an inexpensive material various kinds of optically active chroman derivatives useful as intermediates for medicines, etc. A cyclic hemiacetal (1) obtained from dihydrocoumarin through one step is conve...
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WO/2003/039729A1 |
A process for preparing particles of a substance comprising contacting a first formulation including a first substance with a first solvent stream and a second solvent stream, thereby causing formation of particles of the first substance...
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WO/2003/037954A1 |
A phenolic resin or epoxy resin useful as a resin for semiconductor encapsulation materials, which gives a cured composition having an excellent balance among heat resistance, moisture resistance, crack resistance, and moldability. The p...
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WO/2003/035592A1 |
A method of depolymerizing an aromatic polycarbonate which comprises reacting the aromatic polycarbonate with water, a C1−6 aliphatic alcohol, or a phenol optionally substituted by a C1−10 hydrocarbon group in a supercritical carbon ...
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WO/2003/033649A2 |
A composition comprising a guest/host assembly having a spheroidal host assembly comprised of a hexamer of a methylene-bridged trihydroxybenzene tetramer and a guest component encapsulated within the spheroidal host assembly to provide a...
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