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JP2019182844A |
To provide a novel ketone or oxime compound, an agrochemical containing the same, particularly a herbicide.The present invention provides a ketone or oxime compound, represented by a compound of formula (1) [where B is B-1 or B-2, Q is a...
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JP6576589B1 |
To improve the yield of a halogen compound. The following formulas (1') to include a step of reacting a raw material compound represented by the following formulas (1) to (6) with a halogenating agent in a solvent containing an organic s...
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JP6572392B2 |
wherein R1, R2, and E are defined herein, which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula...
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JP6574203B2 |
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R-R, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the...
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JP6573704B2 |
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
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JP6574444B2 |
Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...
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JP2019147752A |
To provide a compound and a compound for light-emitting element capable of providing a long efficient and long life light-emitting element which emits a light in a wavelength range from a red color region to a near infrared region as the...
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JP2019523248A |
Provided are new compounds of formula (I), in which: X is CH or N, preferably CH; n is 1-5, preferably 1-2; m is 0-5, preferably 1-. 2; and when m is 2-5, two Rs2Radicals can combine with two adjacent carbons of a benzene ring to form a ...
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JP6563384B2 |
The present application relates to a device for regulating the passage of energy from an outside space into an inside space, where the device comprises a switching layer comprising one or more dichroic dyes of a formula (I) or formula (II).
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JP6563017B2 |
Compounds of formula (I)wherein A, R, W, Q, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
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JP6556827B2 |
Compounds according to formula D-S¹-A-B¹, where: A represents -Ar1-(FL-Ar2)n-; Ar1 and Ar2 each represent a bond or an aromatic or heteroaromatic diradical, or two aromatic or heteroaromatic diradicals mutually connected by a singl...
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JP6552061B2 |
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
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JP2019520323A |
Provided are IDO inhibitor compounds of formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, methods of their preparation, and methods for their use in the prevention and / or treatment of diseases....
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JP6529519B2 |
A problem of the present invention is to provide a polymerizable compound and a polymerizable composition which cause little decrease in retardation and discoloration when a film-shaped polymer produced by polymerization is irradiated wi...
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JP6526352B2 |
The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly di...
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JP2019077721A |
To provide a novel histone deacetylase inhibitor.There is provided a compound represented by the following formula or a pharmaceutically acceptable salt thereof. Wherein, R's are each independently selected from H and QR, Qs are each ind...
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JP6518270B2 |
The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is invo...
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JP6518157B2 |
A lubricant, which includes an ionic liquid including a conjugate base and a conjugate acid including 2 or more cations in a molecule of the conjugate acid, wherein the conjugate acid includes a monovalent group including a straight-chai...
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JP6489910B2 |
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JP6488279B2 |
The present invention relates to a compound of formula (I): wherein the substituents are as defined herein, and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are t...
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JP6482344B2 |
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JP6484553B2 |
The disclosures herein relate to novel compounds of formula wherein W, X and Y1, Y2, Y3 and Y4 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of neurological or psychiatric disor...
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JP6474430B2 |
The present invention is directed to an improved process for the preparation of compounds of Formula (II) and Formula (III), which are useful in the inhibition of PDE10. In particular, the present invention is directed to an improved pro...
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JP6470310B2 |
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases ...
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JP2019502688A |
Equation A [Chemical 1]Compound or salt thereof, where Q, X, R1And R2Discloses the compound or a salt thereof as defined herein, which Na is found in sensory and sympathetic neurons.v1.7 It has the property of inhibiting ion channels. Al...
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JP2018203749A |
To provide compositions for treatment and prevention of diseases caused by RNA- or DNA-containing viruses, and concomitant diseases.A pharmaceutical composition comprises a compound having the structure in the figure or a pharmaceuticall...
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JP2018536625A |
Compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, methods of their preparation, and methods of their use in the prevention and / or treatment of HIV, including prevention of the progression of AI...
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JP2018536017A |
The present disclosure includes prodrugs and derivatives of prostaglandins, carbonic anhydrase inhibitors, kinase inhibitors, β-adrenergic receptor antagonists and other drugs for the treatment of eye disorders, and such prodrugs and de...
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JP6430580B2 |
The present invention relates to the use of strobilurine type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing a mutation in the mitochondrial cytochrome b gene conferring resis...
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JP6424285B2 |
wherein W, X and Y1, Y2, Y3 and Y4 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of neurological or psychiatric disorders associated with orexin receptors.
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JP2018150316A |
To provide glutaminase inhibitors.Provided are compounds of formula (I), pharmaceutical compositions comprising these compounds, and uses as glutaminase inhibitors for treating cancers. (In the formula, X is an optionally substituted C-C...
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JP2018527316A |
The present invention provides a compound or tautomer thereof of diazine of formula (I) for use as an antifungal agent, or a pharmaceutically acceptable salt thereof:In the formula, X, N', C', A and E are as defined herein. The present i...
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JP2018526338A |
The present invention relates to the general formula (I): for enhancing the stress tolerance of plants to abiotic stress and for promoting plant growth and / or increasing plant yields:And in the formula, the radicals of formula (I) rela...
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JP2018526339A |
Substituted cyclic aryl-And heteroarylcarbonyl hydrazide. The present invention enhances the stress tolerance of plants to abiotic stress, promotes plant growth, and/Or a general formula for increasing plant production(I)Substituted cycl...
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JP2018526337A |
Substituted heteroarylcarbonyl hydrazide. The present invention is a substituted heteroarylcarbonylhydrazide of the general formula (I) or for enhancing the stress tolerance of a plant to abiotic stress, promoting plant growth and / or i...
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JP2018525341A |
Growth of cancer, viral infections and / or inflammatory disorders, etc. using compounds that regulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds, and thi...
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JP6385560B2 |
The present invention relates to a new compound of formulawherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in partic...
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JP2018116086A |
To provide a resist composition having excellent lithographic characteristics and a resist pattern forming method using the resist composition.The resist composition, which generates acid upon exposure and whose solubility in a developer...
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JP6364025B2 |
The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological condi...
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JP2018104456A |
To provide a compound to treat a subject suffering from or at risk of Raf mediated disease or condition.The present invention provides a compound of formula I, or its salt, prodrug, tautomer or isomer (Ar is an optionally substituted het...
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JP2018515597A |
Described are inhibitor compounds and agents of cathepsins C, CELA1, CELA3A and / or molecules structurally related thereto, compositions containing them, and their use in the suppression and / or prevention of cell and / or tissue necro...
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JP2018515424A |
In particular, the present specification provides methods and compositions that inhibit αvβ1 integrin and treat fibrosis.
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JP6336612B2 |
The present disclosure provides new materials that combine the advantages of well-defined polymeric starting materials and the convenience of surface modification by physical methods into one package and, thus, offers a general and power...
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JP6335268B2 |
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containi...
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JP6333277B2 |
Provided are compounds of formular (I), which can inhibit glutaminase. Pharmaceutial compositions comprising these compounds and uses as glutaminase inhibitors for treaing cancers thereof are also provided.
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JP6332890B2 |
The present specification provides a compound having a spiro structure, and an organic light emitting device including the same.
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JP6333280B2 |
Compounds and compositions comprising compounds that inhibit glutaminase are described herein. Also described herein are methods of using the compounds that inhibit glutaminase in the treatment of cancer.
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JP2018513183A |
Compounds of formula I-VI, including pharmaceutically acceptable salts thereof, as well as compositions and methods for treating human immunodeficiency virus (HIV) infections are described. Equation I is exemplified by the following equa...
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JP6325449B2 |
The present invention provides a compound having a lysine specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, Alzheimer's disease, Parkinson's disease or Hun...
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JP6305845B2 |
where R1 and R2 each represent a hydrogen atom or R1 and R2 form a benzene ring together with carbon atoms to which R1 and R2 are bonded, and R3 represents a straight-chain hydrocarbon group having 10 or more carbon atoms in the general ...
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