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WO/1995/020568A1 |
Salicylates of esterifiable 'beta'-blockers, especially Atenolol-O-Aspirinate, Metoprolol-O-Aspirinate, Pindolol-O-Aspirinate and processes for their preparation are described.
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WO/1995/020570A1 |
The invention concerns hydroxamic-acid derivatives of general formula (I) in which A is hydrogen or a grouping which can be easily splitt off, A1 is hydrogen or alkyl, Ar is an optionally substituted arylene or hetero-arylene group, E is...
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WO/1995/020014A1 |
A process for colouring a synthetic textile material or fibre blend thereof which comprises applying to the synthetic textile material a compound or mixture thereof, which is free from water solubilising groups, of the Formula (1) A-N=N-...
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WO/1995/019956A1 |
Matrix metalloproteinase inhibiting compounds of formula (I), wherein X is a -CO2H or -CONHOH group; R4 is a phenyl or 5- or 6-membered heteroaryl ring wherein any ring nitrogen atom may be oxidised as an N-oxide, which may be optionally...
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WO/1995/019443A2 |
The present invention provides recombinant or chimaeric DNA molecules comprising plant SAR genes, wherein the wild-type genes corresponding to said SAR genes can be chemically induced in a plant in a protein-synthesis independent or in a...
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WO/1995/018797A1 |
Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
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WO/1995/018116A1 |
Arthropodicidal compounds, compositions and use of compounds having formula (I) wherein A, E, X, Y, Z, R1, R2, R3, R4, R5, n and m are as defined in the text.
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WO/1995/018123A1 |
Compounds of formula (I) wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form, or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner kno...
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WO/1995/017180A1 |
The present invention relates to a novel method for treating a mammal suffering from gastrointestinal motility disorders comprising administering to said subject an effective amount of a compound of formula (I) wherein X is oxygen or sul...
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WO/1995/017376A1 |
The invention relates to novel aryl acetic acid derivatives of formula (I) in which Ar, E, G, Q1, Q2 and Z have the meanings given in the description, processes for their production and their use as fungicides.
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WO/1995/016007A1 |
The invention pertains to chiral compounds that contain at least one double or multiple bonded chiral group, at least one polymerizable group, at least one spacer and at least one mesogenic group, and to their use as polymerizable, chira...
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WO/1995/015759A1 |
The present invention is directed to the use of benzothiadiazide derivatives as nootropic agents to treat memory and learning disorders.
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WO/1995/012572A1 |
The present invention provides a compound of formula (I) processes for the preparation of the compounds of the invention in addition to intermediates useful in these processes, a pharmaceutical composition, and a method of treating disor...
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WO/1995/011278A1 |
Diphenylamines have formula (I), in which the ring A may be benzoanellated; D stands for an aryl radical or for a five-membered aromatic heterocyclic residue that has 1 to 3 heteroatoms in the heterocyclic ring selected from the group th...
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WO/1995/009848A2 |
This invention relates to dichelants, in particular compounds having two macrocyclic chelant groups linked by a bridge containing an ester or amide bond, especially compounds of formula (V) (wherein each X which may be the same or differ...
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WO/1995/009846A1 |
Compounds of formula (I) having herbicidal utility are disclosed; wherein Q is a variety of heteroaromatic groups; X is a single bond; O; S; or NR4; R1 is C1-C5 alkyl optionally substituted with C1-C2 alkoxy, OH, 1-3 halogens, or C1-C2 a...
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WO/1995/008604A1 |
Liquid-crystalline compounds have the general formula (I): X(-Y-A-Y-M-Y-B)n, in which X is an aromatic or aliphatic ring system; n is an integer from 2 to 6; the Y symbols represent independently from each other a direct bond, -COO-, -OC...
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WO/1995/007899A1 |
Compounds of formula (I) wherein R1 is a carboxy, alkoxycarbonyl, tetrazolyl, -CO-NH2, -CO-NH-alk, -CO-N(alk)2, -CO-NHOH, -CO-N(alk)OH, -CO-NH-O-R10, -CO-N(alk)-OR10 radical or a group convertible in vivo into a carboxy radical, R2, R3 a...
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WO/1995/005805A1 |
The present invention relates to a process for providing a stable crystallinic form to a fine-grained substance or a substance mixture, which can be produced, stored and used while maintaining the aerodynamic properties required for inha...
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WO/1995/005368A1 |
Fungicidal and insecticidal compounds having general formula (I) or a stereoisomer thereof, wherein A is CH or N; B is OCH3 or NHCH3; M is O and L is N or M is N and L is O or S; and X is alkyl, cycloalkylalkyl, alkoxyalkyl, haloalkoxyal...
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WO/1995/003289A1 |
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...
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WO/1995/002582A1 |
The invention relates to compounds of formula (I) wherein R1 is hydrogen or acyl, R2, R3, R4 and R5 are each independently of the others unsubstituted or substituted alkyl or alkenyl, and X together with the two bonds shown in the formul...
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WO/1995/002423A1 |
Protein, ligand and anti-ligand conjugated chelated metal radionuclides are provided for use in vivo. Intermediates are provided for preparing the compositions efficiently.
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WO/1995/001979A1 |
The present invention relates to novel heterocyclic compounds having general formula (1) wherein: X is O, S, Se, or NR2; Y1, Y2, Y3, Y4 independently are N or CR2; Z is O, S, Se, NR2 or C = N; and A is (a) or (b) wherein W is O, S, NH or...
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WO/1995/001340A1 |
An aldoxime derivative represented by general formula (I), wherein A represents pyrazole, thiazole, etc.; B represents pyridine, pyrazole, thiazole, etc.; and X represents halogen or S(O)nR24. This compound is novel, has an excellent agr...
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WO/1995/000471A1 |
A compound represented by general formula (I) or a possible stereoisomer or optical isomer thereof, and a pharmaceutically acceptable salt thereof (wherein R1, R2, R3 and R4 represent each hydrogen, etc.; R6 and R7 represent each optiona...
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WO/1994/029291A1 |
The invention concerns an aniline derivative of formula (I) wherein R4 includes hydrogen and (1-4C)alkyl; R5 includes hydrogen and (1-4C)alkyl; R6 is hydrogen or (1-4C)alkyl; X3 includes a group of the formula CR7R8 wherein R7 is hydroge...
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WO/1994/026700A1 |
Compounds of formula (I) in which Y is hydrogen, C1-C4alkyl, C1-C4alkoxy, OH, CN, NO2, Si(CH3)3, CF3 or halogen, Z is a group (a) or (b) and R1 is hydrogen, C1-C4alkyl, C2-C4alkenyl, C2-C4-alkynyl, C3-C6cycloalkyl, phenyl which is unsubs...
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WO/1994/026720A1 |
The present invention provides compounds of formula (I) and liquid-crystal compositions containing the compounds, in which R1 is, for example, a straight-chain or branched alkyl radical having 1 to 22 carbon atoms, in which one -CH2- gro...
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WO/1994/026727A1 |
The invention concerns a solid, non-hygroscopic magnesium salt of 3-isopropyl-2,1,3-benzothiadiazin-4-one 2,2-dioxide, a method of preparing it, solid, in particular granular, formulations containing it plus its use in the control of und...
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WO/1994/025434A1 |
Compounds of formula (1) are described where R represents a -CONHOR6 [where R6 is a hydrogen atom or an acyl group], carboxyl (-CO2H), esterified carboxyl, -SR6 or -P(O)(X1R7)- -X2R8 group, where X1 and X2, which may be the same or diffe...
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WO/1994/024098A1 |
Described are NU-fluorosulphonimides of the general formula (I) (R1-SO2)2NF in which each R1 is a methyl group or the R1 groups together form a -(CH2)n- group in which n=1, 2 or 3, in particular N-fluoromethansulphonimide, (CH3SO2)2NF, t...
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WO/1994/022846A1 |
This invention relates to certain heterocyclic compounds and their pharmaceutically acceptable salts, which are useful for sensitizing multidrug-resistant tumor cells to anticancer agents and multidrug resistant forms of malaria, tubercu...
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WO/1994/022842A1 |
This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula (1) (in which A, B, R, Rx, X and Z are defined as in the specification described) and methods for their preparation. These compounds may be used as modulators of ...
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WO/1994/021616A1 |
Compounds having the formula (I), which is explained in detail in the description, may be prepared by conventional methods and used in standard galenic compositions for therapeutical purposes.
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WO/1994/020460A1 |
Angiotensin II receptor antagonists having formula (I) which are useful in the treatment of hypertension, congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of usin...
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WO/1994/020480A1 |
Disclosed are compounds of formula (I) useful in the treatment of cyclooxygenase mediated diseases such as pain, fever and inflammation of a variety of conditions including rheumatic fever, symptoms associated with influenza or other vir...
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WO/1994/020109A1 |
The use of compounds of formula (I) or salts thereof for preparing non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists is disclosed.
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WO/1994/019331A1 |
The invention concerns compounds of formula (I) in which the subscript and the substituents are defined as: n is 0 or 1 to 4; X is 0 or S; Y is a five-membered aromatic heterocycle ring; R1 is nitro, cyano, halogen, alkyl, haloalkyl, alk...
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WO/1994/019329A1 |
This invention relates to substituted cyclic carbonyls and derivatives thereof useful as Human Immnunodeficiency Virus (HIV) protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these com...
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WO/1994/019330A1 |
Pharmaceutically useful compounds having ACAT inhibitory activity of formula (I), wherein n is 0, 1 or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroar...
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WO/1994/018161A1 |
Substituted phenylsulphonamides having formula (I) where the variables are as defined in Claim 1; are selective beta-3 adrenergic receptor agonists with very little beta-1 and beta-2 adregenic receptor activity and as such the compounds ...
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WO/1994/018183A1 |
The invention provides a compound of formula (I), wherein n is an integer of from 0 to 2; R is an optional substituent; R1 is hydrogen or C1-6alkyl; R2 is an atom or group selected from hydrogen, C1-6alkyl (including cycloalkyl and cyclo...
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WO/1994/013629A1 |
The present invention relates to a class of compounds which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of mannitol-derived HIV aspartyl protease inhibitors characterized by specific struc...
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WO/1994/013652A1 |
A compound of formula (I), where E is oxygen or sulphur; A is CR3 or N where R3 is hydrogen or hydrocarbyl; D completes a 5 or 6-membered non-aromatic heterocyclic ring which optionally contains additional heteroatoms selected from oxyge...
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WO/1994/012461A1 |
This invention relates to 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV. The compounds of the present invention are useful in inhibiting PDEIV and in the treatment of AIDS, ast...
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WO/1994/012496A1 |
The invention concerns new pyridyl-1,2,4-thiadiazoles of formula (I), in which R1 is an optionally substituted pyridyl group and R2 is an optionally substituted aryl group, plus their acid addition salts and metal-salt complexes. The inv...
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WO/1994/010159A1 |
Fungicidal and insecticidal compounds having general formula (I), or a stereoisomer thereof, wherein A is CH or N; B is OCH3 or NHCH3; one of L and M is N and the other is S or O; X is an optionally substituted carbocyclic or heterocycli...
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WO/1994/008955A1 |
The present invention relates to a process of preparing N-benzenesulfonimides comprising reacting an alkali metal salt of a sulfonimide with fluorine in the presence of water or water/organic solvent mixtures. N-fluorosulfonimides are us...
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WO/1994/005634A1 |
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production...
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