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WO/2004/041199A2 |
Food products and beverages which include N-acetyl-D-glucosamine (NAG) are provided, as are methods of thier use and preparation. Embodiments of the supplemented food products and beverages are heated to high temperatures, such as those ...
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WO/2004/032826A2 |
An active pharmaceutical ingredient is combined with tannic acid to form a tannate salt complex of the active ingredient. The active ingredient tannate salt complex without isolation or purification is then blended with pharmaceutically ...
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WO/2004/031244A1 |
The present invention is directed to novel methods to produce carbohydrate polymers and oligomers especially for pharmaceutical and food industries. The invention is directed to methods to remodel monosaccharides, and/or oligosaccharides...
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WO/2004/031396A2 |
Methods for cell-free production of glucosamine from starch, maltodextrin or glycogen or from fructose and a source of amino groups are disclosed. Also disclosed are cellular extracts comprising glucosamine-6-phosphate synthase activity,...
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WO2003097657A9 |
The present invention relates to novel thioglycosides of D-galactofuranose that have an antimicrobial action, methods for their synthesis, pharmaceutical compositions containing them and methods for the treatment of patients suffering mi...
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WO/2004/017810A2 |
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific termin...
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WO/2004/014929A1 |
New compounds and methods for the preparation of combinatorial libraries of potentially biologically active compounds are based on monosaccharides of formula (I) being a derivative of a furanose or pyranose form of a monosaccharide.
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WO/2004/005308A2 |
This invention relates to processes for production of alkylamino glucosaminide phosphate compounds, and of disaccharide compounds, including various novel intermediates and intermediate processes. In one aspect, glycosyl halides are prod...
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WO/2003/105769A2 |
The invention is directed to compounds of formula (I) wherein X is O, OR NH; R’ is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q’ is optionally present and may be a C1-10 h...
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WO/2003/103722A1 |
The invention provides MRI detectable species of formula (I): Dp-Sn-Nm, wherein D is a MRI detectable moiety; S is a spacer; N is a molecule of a nutrient or pseudo-nutrient; n is 0 or an integer; m is an integer and p is an integer. The...
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WO/2003/101405A2 |
The present invention relates to aminoglycoside compounds having antibiotic activity. Moreover, the present invention relates to L-aminoglycoside compounds and diastereomers thereof which posses antibiotic activity and are not susceptibl...
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WO/2003/097656A2 |
The present invention is directed to novel compounds of the formula (I) wherein X, R1, R2 , R3, R4, R5 and R6 are as described in the specification, processes for the preparation of and pharmaceutical compositions comprising said derivat...
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WO/2003/090696A2 |
The invention features methods and products associated with non-invasive delivery of polysaccharide preparations.
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WO/2003/087116A1 |
The present invention teaches novel compositions and methods for altering the sweetness delivery profile of 4, 1', 6'-trichloro-4, 1', 6' trideoxygalactosucrose. This. invention also teaches novel uses for compositions comprising 4, 1', ...
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WO/2003/086356A1 |
Pharmaceutical compositions consisting of diphenhydramine tannate in solid dosage form which are effective when administered for the symptomatic relief of sneezing, itchy, watery eyes, itchy nose or throat and runny nose due to hay fever...
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WO/2003/087117A1 |
The present invention relates to novel methods for stabilizing aqueous deacylation, via use of buffers in the production of sucralose. The present invention provides a process for producing sucralose from an acyl-sucralose compound where...
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WO/2003/086394A1 |
The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containin...
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WO/2003/086346A1 |
A therapeutic composition comprises diphenhydramine tannate in the substantial absence of other active ingredients. The composition has utility in providing symptomatic relief of sneezing, itchy, watery eyes, itchy nose or throat and run...
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WO/2003/078358A2 |
This invention relates to the miniaturisation of radiosyntheses onto microfabricateddevices, and in particular to use of microfabricated devices for radiosynthesis, isolation, and analysis of radiotracers for use in Positron Emission Tom...
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WO/2003/076453A1 |
The present invention relates to novel extractive methods for purifying sucralose. The present invention also relates to compositions comprising the sucralose preparations made by the methods of the present invention.
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WO/2003/076454A1 |
This invention relates to processes for purifying sucralose by the use of an initial non-crystallization purification procedure followed by three or more sequential crystallization steps and recycle of the mother liquor remaining from ea...
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WO/2003/073988A2 |
Disclosed are glycosides, orthoester glycosides and glycuronamides of fluoxetine and analogs thereof to treat conditions and diseases such as depression.
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WO/2003/070715A1 |
A compound of general formula (I): wherein R1 and R2 may be the same or different and are selected from the group consisting of hydrogen, optionally substituted C4−30 alkyl and optionally substituted C4−30 alkenyl, provided that R1 a...
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WO/2003/070738A2 |
The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co−crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceuti...
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WO/2003/066186A2 |
The invention relates to integrating at least two processes that use at least one acid, wherein one process utilizes an ion−exchange purification step.
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WO/2003/059866A1 |
Compounds represented by the general formulae (I-1), (I-2), (I-3) and (I-4) and having excellent antitumor activity: (I-1) (I-2) (I-3) (I-4) wherein R1, R2, R3, m, n and R4 are each as defined in the description.
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WO/2003/059924A1 |
The present application describes a binding epitope to Helicobacter pylori, namely substances comprising the oligosaccharide sequence -Gal(Nac)r2&dollar g(b)4Glc(A)q2(Nac)r3-, and the use thereof in pharmaceutical and nutritional composi...
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WO/2003/055897A1 |
Method for preparing a compound comprising protonated glucosamine and CI?-¿, Na?+¿ and SO¿4??2-¿ ions, in which (a) glucosamine hydrochloride and a stoichiometric excess of sodium sulphate are placed in water, (b) the mixture obtaine...
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WO/2003/053448A1 |
This invention relates to a process for the preparation of glucosamine sulphate, glucosamine hydroiodide, glucosamine pyruvate, glucosamine phosphate or their mixtures with glucosamine hydrochloride, by electrodialysis. Starting from glu...
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WO/2003/049696A2 |
The invention pertains to compositions containing glucosamine and organic acids, methods of making such compositions and methods of using such compositions.
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WO/2003/047501A2 |
A treatment for cancer, and in particular, of therapeutic compounds which block the ability of cytokines and chemokines to promote metastasis of malignant cells. The therapeutic compound comprises a carboxylated and/or sulfated oligosacc...
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WO/2003/044033A1 |
Immunosuppressants each containing as the active ingredient at least one member selected from the group consisting of compounds represented by the general formula (1) and pharmaceutically acceptable salts thereof: (1) wherein R101 is an ...
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WO/2003/044034A1 |
The present invention relates to heterodimeric conjugates of neomycin-chloramphenicol of formula 1, their preparation and their use. Because of their heterodimeric structure, they can recognize both stem and loop of RNA motif and show bi...
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WO2002043653B1 |
The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic...
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WO/2003/033522A1 |
The invention relates to a process for isolating a lectin composition, in particular comprising the mannose-binding lectin (MBL), suitable for using recombinantly produced lectins as starting material, as well as methods for enriching a ...
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WO/2003/020735A1 |
The invention relates to methods for the sulfation of saccharides. In particular, the invention relates to methods for the sulfation of low molecular weight saccharides derived from glycosaminoglycans.
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WO/2003/018598A2 |
Monosaccharide (pyranoside) conjugates of the formula have been found to be useful as enhancers and/or inhibitors of heparin binding to FGF. The compounds have the potential to be useful in regenerative medicine or for treatment of patho...
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WO/2003/017931A2 |
The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmon...
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WO/2003/016915A1 |
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present inventionis related to a method of determining an oligosaccharide sequence, which comprises a tumor specific termina...
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WO/2003/010178A1 |
The invention concerns disaccharides of formula (I) derived from $g(a)-maltosyl fluoride, wherein R?1¿ and R?2¿ are such as defined in Claim 1. Said disaccharides are useful as glycosyl donors in transglycosylation reactions catalysed ...
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WO/2003/010155A1 |
The invention relates to a method for producing novel spinosyn derivatives, which are substituted in the C-21 position by a 1-hydroxy-ethyl radical, to novel spinosyn derivatives of this type per se and to their use for producing novel s...
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WO/2003/008431A1 |
A process for producing a sugar chain asparagine derivative. According to this process, various isolated sugar chain asparagine derivatives which are useful in the field of developing drugs, etc. can be easily obtained in a large amount,...
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WO/2003/002157A1 |
The present invention relates to novel solid-phase processes for the production of radiolabelled tracers, in particular for the production of ?18¿F-labelled compounds which may be suitable for use as Positron Emission Tomography (PET) r...
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WO/2002/100875A1 |
The invention provides crystals of oligosaccharides which are useful as raw materials or intermediates for health foods, drugs, cosmetics and so on&semi and processes for preparation of the crystals which are suitable for mass or industr...
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WO/2002/100874A1 |
The invention relates to compounds of formula (I) wherein A respectively and independently from the other A group(s) represents a group comprising a ring of 5-6 ring atoms, said ring carrying at least one amino substituent selected from ...
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WO/2002/090370A1 |
An asymmetrically bicipital lipid which is represented by the general formula: R-NHCO-(CH¿2?)¿n?-COOH (I) wherein R represents a residue obtained by removing a reduced terminal hydroxyl group from an aldopyranose, n represents a number...
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WO/2002/079394A2 |
The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by react...
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WO/2002/077002A2 |
The present invention provides selenium derivatives of nucleosides, nucleoside phosphoramidites, nucleotides, nucleotide triphosphates, oligonucleotides, polynucleotides, and larger nucleic acids and methods for their synthesis. Selenium...
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WO/2002/072593A2 |
The present invention relates to alkylated C-sugars which are now carbohydrate derivatives based on the 'C-Sugar' platform. These alkylated C-sugars are converted from hydrophilic, hydrogen-bonded saccharide derivatives and are very stab...
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WO/2002/067948A1 |
The present invention discloses the use of N-acetyl-D-glucosamine in the manufacture of pharmaceutical useful for preventing and treating sexual disorder. The formulation comprising of N-acetyl-D-glucosamine as main active ingredient is ...
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