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WO/2002/066667A1 |
Glucosamine suitable for human or animal consumption is disclosed. The glucosamine is derived from microbial biomass containing chitin. Suitable starting materials include substantially uniform microbial fungal sources, such as fungal so...
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WO2002032915B1 |
The present invention provides a monosaccharide compound of general formula I as shown in the specification. The invention also provides processes for the preparation of the compound of formula I and methods of screening for antibacteria...
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WO/2002/057281A2 |
The present invention provides aminoglycosides and pharmaceutical compositions that include the aminoglycosides. The aminogylcosides are useful to treat or prevent infectious diseases (e.g., bacterial infections) in a mammal (e.g., human).
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WO/2002/057284A1 |
The present invention relates to novel compounds, the use of said compounds as a medicament as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galectin to receptors in a mammal. Said gale...
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WO/2002/056874A2 |
Novel nitric-oxide releasing lipid molecules are provided which comprise a lipid molecule selected from (a) phosphoglycerides, (b) lipids having a sphingosine base as a backbone, (c) monoacylglyerols, (d) diacylglycerols, (e) glycosylacy...
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WO/2002/053572A1 |
The invention relates to compounds which are useful in the delivery of a wide variety of therapeutically useful molecules. In particular, the invention relates to compounds which are able to act as carriers for therapeutically useful mol...
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WO/2002/046240A1 |
A method of preparing multicomponent salts of a compound in aqueous solution includes the steps of first selecting at least a weak acid, then selecting at least a first weak base, mixing an equivalent mole amount of the weak acid with th...
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WO/2002/043678A2 |
The invention relates to a method for the enzymatic fixation of derivatised carbohydrates to fibrous, in particular keratinous materials, such as hair or wool, to a multi-component system comprising at least one carbohydrate derivative a...
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WO/2002/044397A1 |
It is intended to provide a process whereby a substance positive in Elson-Morgan reaction can be industrially, economically, easily and stably produced; a process for producing a composition containing a substance positive in Elson-Morga...
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WO/2002/040495A2 |
The present invention provides an improved form of sucralose and a process for making it.
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WO/2002/036173A2 |
The present invention provides novel diagnostic compositions comprising a radiolabeled LTB4 binding agent and a radiolabeled perfusion imaging agent, diagnostic kits comprising such compositions, and methods of concurrent imaging in a ma...
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WO/2002/017890A2 |
A 2-glucosamine derivative of the general formula (I) wherein R is an alkyl radical of the general formula C¿n?H¿2n+1? and n is selected from 2-12; and pharmaceutically acceptable salts, esters and glucosides thereof, used for a treatm...
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WO/2002/018449A1 |
The present invention provides a new class of compounds presenting a high compatibility with tissues and organic fluids. Such new compounds are polysaccharides essentially formed of units of uronic acid and/or hexosamine, containing nitr...
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WO/2002/012254A1 |
A process for producing hydrazinomonosaccharide derivatives and use of hydrazines in determining the structures of aldose and ketose monosaccharides located at the reducing ends of saccharides.
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WO/2001/094367A1 |
Substances which hinder human $g(a)-amylase potently and are effective in the prevention and treatment of hyperglycemia such as diabetes and diseases due thereto; and $g(a)-amylase inhibitors and preventive or therapeutic drugs for hyper...
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WO2000030656A9 |
The present invention is directed to compositions comprising 1-( beta -D-ribofuranosyl)-1H-1,2,4-triazole compounds and either endogenous or exogenous neurotrophic factors. Methods of using such compounds and compositions are also provid...
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WO/2001/093701A2 |
The present invention is directed to compositions which are useful for promoting one or more health benefits including, for example, promoting joint health, bone health, cardiac health, and/or anti-inflammation. The present invention is ...
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WO/2001/087235A2 |
A method for producing [?18¿F] fluoride ion comprises loading an enclosed chamber (16) of a metal target with [?18¿O]oxygen gas. The [?18¿O] oxygen gas is irradiated in the enclosed chamber (16) to produce [?18¿F] fluoride ion in the...
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WO/2001/087902A2 |
The invention concerns a method for treating plant material by applying a compound of formula (I') wherein: A¿6?, A¿4? and A¿3?, independently of one another, represent OH or OR¿5? or OC(O)R¿5? or O-SO¿2?-R¿5? or O-(CH¿2?)¿n?-NR...
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WO/2001/085745A1 |
Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or...
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WO/2001/085747A1 |
Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or...
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WO/2001/077122A1 |
This invention relates to novel highly functionalized phosphine ligands as ancillary ligands in radiopharmaceuticals. Also, this invention provides radiopharmaceuticals comprised of highly functionalized phosphine ligated ?99m¿Tc labele...
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WO/2001/074780A1 |
The present invention relates to a chemical composition comprising a pyridine carboxy derivative and an H2 histamine receptor antagonist and a pharmaceutical composition or a dietary supplement comprising a pyridine carboxy derivative an...
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WO/2001/070724A1 |
The present invention relates to a complex comprising one or more radioisotopes selected from the group consisting of ?99m¿Tc, ?188¿Re and ?186¿Re chelated to a glucose derivative having an intramolecular nitrogen or sulfur atom, whic...
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WO/2001/064699A1 |
6-Deoxy-6-carbonylthioglucopyranosyl acetimidates of the general formula (I) [wherein R?11¿, R?12¿ and R?13¿ are each independently alkyl or silyl; R?14¿ is hydrogen, alkyl, or aryl; R?15¿ is alkyl; and R?16¿ is hydrogen or alkyl]....
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WO/2001/057053A1 |
The invention concerns a novel method for preparing by chemical process functionalised $g(b)-(1,3)-glucan derivatives, enabling to obtain free oligosaccharides or comprising specific groups such as, for instance, sulphate, phosphate, met...
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WO/2001/054691A1 |
Nitrate salts of antimicrobial agents for the preparation of antimicrobial medicaments, specifically antiviral, antifungal and antibacterial medicaments.
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WO/2001/051003A2 |
The invention provides novel methods for treating disease based on the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiol...
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WO/2001/029039A1 |
The present invention is directed to 9-substituted guanine derivatives in which the guanine moiety is linked to another moiety with physiological or pharmacological activity through a carboxamide linkage. The number of carbon atoms betwe...
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WO/2001/023398A1 |
The present invention relates to a process for the preparation of oligosaccharides or oligosaccharide containing compounds, especially N-acetyl-chitooligosaccharides having a fucosylated monosaccharide. The invention also relates to nove...
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WO/2001/019960A1 |
Chimeric carbohydrates produced by recombinant microorganism carrying exogenous glycosyl transferases act with or without exogenous enzymes required for synthesis or nucleotide synthesis precursors. These recombinant microorganism can be...
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WO/2001/002412A1 |
The present invention relates to derivatives of 5-nitrofurfural which are useful as anticancer agents, antiviral agents, immunoprotentiators and/or as agents which may be used for combating illnesses which arise due to an elevated cell p...
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WO/2001/000621A1 |
The invention concerns compounds of formulae (Ia) or (Ib) wherein M: represents a molecule for use in the treatment or diagnosis of pathologies affecting the cartilage; R¿1?, R¿2?, R¿3? represent an alkyl group, or R¿1?, R 2, R¿3? t...
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WO/2001/000564A1 |
The invention relates to a method for producing amines by reacting aldehydes with ammonia in the presence of hydrogen and of a hydrogenating catalyst while adding disodium tetraborate.
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WO2000020428A9 |
One aspect of the present invention relates to differentially protected glycosyl phosphates. Another aspect of the present invention relates to the preparation of glycosyl phosphates from glycal precursors. In another aspect of the prese...
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WO/2000/055165A1 |
The invention relates to the industrial conversion of carbohydrates, alcohols, aldehydes or polyhydroxy compounds in aqueous phase. According to the invention a catalytic method is used for the conversion, using a metal catalyst consisti...
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WO1999033836A9 |
Compounds defined by general structure (II) are disclosed. These compounds display pharmacological activities, including inhibition of tyrosine kinase activity and enhancement of the function and/or survival of trophic factor responsive ...
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WO/2000/050621A2 |
A process for producing aldehydes, and/or carboxylic acids is described, in which a primary alcohol, especially a carbohydrate, is oxidised using a catalytic amount of a nitrosonium compound obtained by oxidising a nitroxyl compound in t...
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WO/2000/050388A1 |
A process for producing nitrosonium ions is described, in which a nitroxyl compound such as TEMPO is oxidised using an oxidising agent in the presence of a complex of a transition metal such as Mn, Fe, Cu, and a complexing agent such as ...
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WO/2000/042057A1 |
The invention provides collections of orthogonally-protected monosaccharides as universal building blocks for the synthesis of glycoconjugates of non-carbohydrate molecules, neo-glycoconjugates and oligosaccharides. This orthogonal prote...
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WO2000004036A9 |
The present invention relates, in general, to a nucleoside base and, in particular, to a universal, photocleavable nucleoside base. The invention further relates to oligonucleotides comprising such a base.
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WO/2000/031059A1 |
The invention concerns compounds of formula (I) wherein: A represents R¿1? or(O)R¿1? where R¿1? represents an alkyl group comprising 1 to 30 carbon atoms, linear or branched, saturated or unsaturated, capable of being partly or totall...
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WO/2000/020392A1 |
The invention relates to aryl-substituted propanolamine derivatives and their pharmaceutically acceptable salts and functional derivatives. The invention relates to compounds of formula (I), wherein the radicals have the defined meanings...
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WO/2000/011010A1 |
The invention concerns a novel phosphoglycolipid compound. The compound of the subject invention is 2- Deoxy-6-$i(O)- [2-deoxy-4-$i(O) -phosphono-3-$i(O) -[($i(R))-3- tetradecanoyloxytetradecanoyl] -2-[($i(R))-3- octadecanoyloxytetradeca...
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WO/2000/008038A2 |
Solid phase synthetic methods of forming sulfur-linked disaccharides and oligosccharides are described, wherein a saccharide or oligosaccharide bearing a protected thiol-group at the anomeric carbon is immobilized onto a solid support at...
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WO/2000/007602A1 |
The present invention is based on the identification of compounds in the form of biosynthetic precursors which can be used to modulate neuronal growth, inhibit cellular entry by pathogens and modulate immune responses. The invention furt...
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WO/2000/006115A1 |
Sialyl oligosaccharides and derivatives useful for regulating inflammatory responses, and treating related disorders and conditions, and/or improving the texture or appearance of the skin, as well as topical pharmaceutical and cosmetic c...
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WO/2000/004182A1 |
The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present me...
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WO/2000/004035A1 |
A method for forming a glycosidic linkage by: (a) contacting a glycoside bearing an anomeric sulfoxide group with a compound bearing a free hydroxyl group in the presence of an organic acid anhydride and a scavenger of sulfenyl esters; a...
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WO/1999/061455A1 |
Glucosamine compositions comprising the compounds glucosamine sulfate metal chloride, wherein the metal, i.e., the cation is potassium, sodium, magnesium, zinc, lithium or manganese. The compounds have purity levels of at least about 97 ...
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