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WO/1997/017471A1 |
New intercalating asymmetric cyanine dyes are provided in which the benzothiazole portion of the cyanine dye has been modified to produce dyes with improved properties for labelling nucleic acids, such as longer wavelengths and improved ...
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WO/1997/017076A1 |
New intercalating cyanine dyes are provided in which the benzothiazole portion of the cyanine dye has been modified to produce dyes with improved properties for labelling nucleic acids. This class of fluorescent cyanine dyes are represen...
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WO/1997/013810A1 |
The present invention is directed to fluorescent dyes and its valence tautomers of formula (I), wherein Q represents a conjugated moiety that increases the fluorescent quantum yield of the compound; R1 is a functionalized group of the fo...
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WO/1997/008552A1 |
Fluorescent and chemiluminescent labelling compositions comprise a linear polysaccharide backbone molecule having a plurality of target-binding molecules, such as antibodies or nucleic acids, attached at spaced-apart intervals thereon. E...
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WO/1996/041166A2 |
Methods and compositions are provided for determining the potential of a membrane. In one aspect, the method comprises: (a) introducing a first reagent comprising a hydrophobic fluorescent ion capable of redistributing from a first face ...
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WO/1996/040997A1 |
Disclosed is a method of fluorescent detection of a nucleic acid. The method comprises contacting to the nucleic acid a bis-dicationic aryl furan and exposing the nucleic acid to light at a frequency to induce fluorescence of the compoun...
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WO/1996/037629A1 |
Water-soluble salts of hydrazone compounds react quickly with aniline compounds in the presence of a peroxidase and hydrogen peroxide to provide a color which can be measured spectrophotometrically or visually, either in solution or when...
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WO/1996/036882A1 |
This invention describes the use of merocyanine dyes, including styryl dyes, for detecting and quantifying poly(amino acids) by absorbance or fluorescence. Poly(amino acids) are detected in solution, in electrophoretic gels, or on solid ...
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WO/1996/033406A1 |
A process and a kit are provided for detecting differences in two or more samples of protein. Protein extracts are prepared, for example, from each of a different group of cell samples (1, 2) to be compared. Each protein extract is label...
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WO/1996/023525A1 |
A diagnostic marker comprising (a) a system for assaying, for example, an antibody and (b) a fluorescent functional group represented by general formula (I) which is bonded to this assay system, wherein R1 and R2 independently represent ...
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WO/1996/017892A1 |
Disclosed are methine dyes of formula (I), in which K is a carbocyclic or heterocyclic radical, X is nitrogen or a radical of the formula C-Q1 and Q1, Q2 and Q3 are hydrogen, optionally substituted C1-C6 alkyl, C3-C8 cycloalkyl, optional...
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WO/1996/017628A1 |
An in-vivo diagnostic process by near infrared radiation (near I.R. radiation) uses water-soluble dyes and their biomolecular addition products having certain photophysical and pharmacochemical properties as contrasting agents for fluore...
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WO/1996/015196A1 |
The invention concerns azamethine dyes of formula (I) in which W is oxygen, sulphur or a group of the formula -NH-CO-, -NH-COO- or -NH-SO2-, Z1 is C1-C4 alkyl which may also be substituted, phenyl or C1-C4 alkoxy, Z2 and Z3 are hydrogen ...
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WO/1996/015195A1 |
The invention concerns pyridone dyes of the formula (I) in which X is nitrogen or CH, R1 is a five-membered or six-membered carbocyclic or heterocyclic group, R2 is cyano, carbamoyl, C1-C6 alkoxycarboyl or C1-C4 alkanoyl and R3 is option...
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WO/1996/013552A2 |
The invention describes the preparation and use of fluorescent stains for nucleic acids derived from unsymmetrical cyanine dyes comprising a substituted benzazolium ring system linked by a methine bridge to a pyridinium or quinolinium ri...
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WO/1996/004405A1 |
Novel fluorescent heterodimeric DNA-staining energy transfer dyes are provided combining asymmetric cyanine azole-indolenine dyes, which provide for strong DNA affinity, large Stokes shifts and emission in the red region of the spectrum....
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WO/1996/000745A2 |
The present invention provides novel hydrosilation-curable compositions, the cure of which can be monitored visually, comprising: (1) an ethylenic compound; (2) a compound containing silicon-bonded-hydrogen groups; (3) a hydrosilation ca...
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WO/1996/000902A1 |
The present invention relates to iminium ion substitute cyanine dyes having a fluorescence absorbance of between about 500 and 900 nm, a reduced tendency to aggregate and enhanced photostability. The cyanine dyes of the present invention...
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WO/1996/000560A2 |
The present invention provides novel dental impression materials, the cure of which can be monitored visually, comprising: (1) a curable silicone polymer; (2) a crosslinker compound containing silicon-bonded-hydrogen groups; (3) a hydros...
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WO/1996/000409A1 |
The invention concerns the use, in non-linear optics, of naphthalene derivatives of formula (I) in which rings A and B may be fused each other, X is nitrogen or a group of the formula CH or CH=CH-CH: Z is a heterocyclic group and, in the...
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WO/1995/030901A1 |
Disclosed is a method of fluorescent detection of a nucleic acid. The method comprises contacting to the nucleic acid a bis-dicationic aryl furan compound, such as 2,5-bis[4-(4, 5, 6, 7-tetrahydro-1H-1,3-diazepin-2-yl)phenyl]furan; 2,5-b...
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WO/1995/029958A1 |
The invention concerns methine dyes of formula (I) in which: R means hydrogen, optionally substituted C1 to C10 alkyl or optionally substituted phenyl; X means nitrogen or a residue of the formula CQ1, CH=CQ1-CH, CH=CH-CH=CH-CH, (i) or (...
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WO/1995/028447A1 |
A disperse dye of formula (1), in which R1 is alkyl, cycloalkyl, aryl, alkenyl or aralkyl each of which may be optionally substituted; R2 and R3 each independently is optionally substituted alkyl; R4 is -H, -OH or alkyl, alkoxy, - NHCOal...
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WO/1995/023355A1 |
Photothermographic elements of the photothermographic type may be sensitized to the infrared with sensitizing dyes of formula (I), wherein R1 represents a (CH2)n-COO- group of from 1-20 carbom atoms, or an alkyl group of from 1 to 20 car...
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WO/1995/022581A1 |
The invention relates to triazolopyridine dyes of formula (I) where one of the two groups A and E stands for nitrogen and the other stands for a group of formula C-R1, in which R1 stands for optionally substituted C1-C20 alkyl, optionall...
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WO/1995/021219A1 |
Disclosed is a method for preparing methine or azamethine dyes based on pyridine dyes, wherein oxime- or formylpyridine or a tautomeric form thereof is condensed with 5-membered aromatic heterocycles.
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WO/1995/020181A1 |
Dyes having formula (I), in which R1 stands for halogen, cyano or thiocyanato; R2 stands for possibly substituted C1-C8-alkyl or possibly substituted phenyl; R3 stands for a 5- or 6-membered aromatic carbocyclic or heterocyclic residue; ...
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WO/1995/017470A1 |
Pyridone dyes of formula (I) in which X is nitrogen or C-CN, R1 and R2 are optionally substituted C1-C10 alkyl, C5-C7 cycloalkyl, C3-C4 alkenyl, optionally substituted phenyl or R1 and R2 together with the nitrogen atom bonding them are ...
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WO/1995/015144A1 |
Keratin-containing fibres, in particular human hair, are dyed using dyes using dyes of formulae (1) to (9) indicated in claim 1.
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WO/1995/011942A1 |
A thiophene-1,1-dioxide of formula (1), wherein D is a group of formula (2) or formula (3): R1 and R2 each independently is -H or alkyl, cycloalkyl, aryl or alkenyl, each of which may be optionally substituted; R3, R4, R5 and R6 each ind...
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WO/1995/011278A1 |
Diphenylamines have formula (I), in which the ring A may be benzoanellated; D stands for an aryl radical or for a five-membered aromatic heterocyclic residue that has 1 to 3 heteroatoms in the heterocyclic ring selected from the group th...
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WO/1995/007888A1 |
Method for the preparation of high purity substituted benz[e]indoles of general formula (I), consisting in preparing an arylhydrazine which is subjected to a Fischer indole synthesis with a suitable ketone, the benz[e]indole so obtained ...
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WO/1995/007950A1 |
The present invention relates to a process for the production of cyanine dyes with their methine chain showing group (M) and the charge compensation occurring by linked end groups through transformation of cationic cyanine dyes comprisin...
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WO/1995/004953A1 |
Optically non-linear materials suitable upon repeated Langmuir-Blodgett dipping for forming Z-type (head-to-tail) films for second harmonic generation include hemicyanine dyes which are very unsymmetrical, i.e. which have hydrophobic sub...
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WO/1995/001772A1 |
Keratin-containing fibres, in particular human hair, are dyed using dyes of formulae (1) to (6) indicated in claim 1. These dyes make it possible to dye by the trichromatic principle even in dark shades.
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WO/1994/026931A1 |
Novel fluorescent dyes are provided, characterized by having a fluorophore joined to a polycationic chain of at least two positive charges. The dyes are found to provide for high enhancement upon binding to nucleic acid and have strong b...
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WO/1994/024213A1 |
The invention describes the preparation and use of fluorescent stains for nucleic acids derived from unsymmetrical cyanine dyes comprising a substituted benzazolium ring system linked by a methine bridge to a pyridinium or quinolinium ri...
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WO/1994/021471A1 |
Proposed are ink ribbons containing one or more compounds from the group comprising the phthalocyanines, the naphthalocyanines, the nickel dithiolene complexes, the methine dyes and the azulene quaternary-acid dyes, all of which have the...
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WO/1994/017397A1 |
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropr...
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WO/1994/011200A1 |
An assemblage for use according to thermal dye transfer methods, consisting of a dye-donor element and a receiving element containing on a support a dye receiving layer comprising a homo- or copolymer of vinylchloride, said dye donor ele...
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WO/1994/010248A1 |
A pyrrolidone dye of Formula (1), wherein: D is a group of Formula (2), or a group of Formula (3), or a group of Formula (4), R1 is alkyl, cycloalkyl, aryl, alkenyl or aralkyl each of which may be optionally substituted; R2 is optionally...
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WO/1993/024859A1 |
The invention relates to novel optically non-linear materials comprising a film forming hemicyanine dye having an amphiphilic anion.
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WO/1993/020477A1 |
Nonlinear optical elements are disclosed which comprise a polyimide which is solution and/or melt processible, and a poled NLO dye. Also disclosed is a process for making such elements, and devices in which they can be used. Disclosed NL...
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WO/1993/015596A2 |
Nonlinear-optic (NLO) compositions containing functionalized merocyanine dyes, such that the molecules, comprising the NLO-active compositions have a functional group at each end of the molecule and each functional group differing in rea...
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WO/1993/011458A1 |
A photographic element is described with improved speed in the blue and ultra-violet region of the electromagnetic spectrum. The spectral response of the photographic element is enhanced with at least one dye represented by formula (I), ...
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WO/1993/011120A1 |
Compounds are provided having the capability of binding therapeutically active substances to lipid containing bio-compatible particles, such as cells or viruses. These compounds include a bio-affecting moiety, comprising a therapeuticall...
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WO/1993/008505A1 |
The present invention relates to polymethine spectral sensitising dyes comprising at least one intracyclic thioether function macrocycle. These special sensitising dyes may be used in silver halide photographic products. These spectral s...
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WO/1993/006482A1 |
The invention relates to dimers of unsymmetrical cyanine dyes, typically dimers of benzthiazole or benzoxazole derivatives, that exhibit enhanced fluorescence on binding with DNA or RNA. The dimers generally have formula (1), where R1 an...
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WO/1992/021064A1 |
A novel blocked filter dye comprises a new blocking group that (a) comprises two electrophilic groups, the least electrophilic of which is bonded directly or through a timing group to the filter dye group of the compound, (b) is capable ...
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WO/1992/019684A1 |
Pyridone dyes of formula (I), wherein R?1� stands for hydrogen or C�1?-C�4? alkyl, R?2� and R?3� may be identical or different and independently stand for hydrogen, optionally substituted C�1?-C�12? alkyl, C�5?-C�7? cyc...
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