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JPS5422516B2 |
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JPS5489087A |
PURPOSE: To increase the concentration of the produced androstane compound having dehydrogenated A-ring in the microbiological oxidation of sterols, by adding activated charcoal to the cultivation medium. CONSTITUTION: An androstane comp...
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JPS5467096A |
PURPOSE: To accumulate an androstane derivative having de-hydrogenated A-ring by the microbial oxidation of sterols in a medium containing lanolin fatty acid. CONSTITUTION: To prepare an androstane derivative having de-hydrogenated A- ri...
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JPS5464694A |
PURPOSE: To prepare purified androstane compound by treating a crude androstane compound obtained by the microbial oxidation of sterols, with activated charcoal. CONSTITUTION: A fermentation liquid containing an androstane compound is pr...
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JPS5449393A |
A fermentation process for the preparation of 7 alpha -hydroxylated steroids utilizing strains of the genus Mucor is disclosed. The 7 alpha -hydroxylated steroids are useful intermediates for the synthesis of chenodeoxycholic acid as wel...
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JPS543954B1 |
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JPS5396389A |
PURPOSE: To prepare 3-keto-steroid by culture of microorganisms, which are capable of decomposing sterol, in culture ground contg. organic solvents.
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JPS5392754A |
Corticoids of formula (I) are new (..... indicates a single or double bond; X is beta-hydroxymethylene or CO; R1 is H or physiologically tolerable acid residue. R2 is F, Cl or CH3). They are prepd. e.g. by hydroxylation of 11-unsubstd. c...
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JPS5386092A |
PURPOSE: To prepare sterol by culturing sterol-producing bacteria belonging to Aureobasidium genus in a nutrient medium.
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JPS5326383A |
To activate immobilised living microorganisms for the conversion of steroids, antibiotics and other compounds, peptone, glucose or a mixture of peptone and glucose, advantageously in a concentration of 0.1 to 1.0 % (wt./vol.), is added t...
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JPS5312492A |
PURPOSE: To oxidize industrially sterols, their 4-ene-3-one derivatives or 1, 4diene-3-one derivatives with microorganism using an improved culture ground.
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JPS52148688A |
PURPOSE: To improve the yield of the oxidation products such as DHT, 4AD, and ADD, by the microbial oxidation of sterols or their specific derivatives in a medium containing ash of molasses.
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JPS52111551A |
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JPS52102499A |
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JPS5257161A |
PURPOSE: To separate selectively androstane compounds whicha re useful as raw materials of oral contraceptives with ease by applying the specfic adsorbents to the microbial oxidation products of steros.
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JPS5210870B1 |
1,255,950. 18-Methylene steroids. CIBAGEIGY A.G. 20 Dec., 1968 [22 Dec., 1967; 25 Nov., 1968], No. 60763/68. Heading C2U. 18-Methylene steroids are prepared (1) by heating N-oxides of tertiary 18-aminomethyl steroids; or (2) by splitting...
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JPS5210485A |
A method is disclosed for improving the activity of oxireductase enzymes, the improvement consisting in that an enzyme and a previously functionalized coenzyme are embedded in a filamentary structure, the coenzyme having previously been ...
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JPS522920B2 |
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JPS51112515A |
PURPOSE: A process for preparing novel 3,16α-dihydroxy-5-en-steroid-3hemiacylate, and entiserum highly specific to 16α-hydroxy-5-en steroid by the use of this novel compound.
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JPS5132626B1 |
Cpds. of partial general formulae I - IV where R'=OH or Oacyl and R2 = H or R'+R2 together = O R3 = H, beta-OH, beta-Oacyl, beta-halogen or alpha-halogen R4 = H or R3+R4 together = O R5 = halogen, OH or Oacyl R6 = H or R5+R6 together = a...
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JPS50148583A |
The new enzyme steroid- DELTA -isomerase is provided, as well as a process for producing same, comprising digesting a micro-organism containing said isomerase, extracting same by destruction of the cell wall with a buffer solution contai...
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JPS50142787A |
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JPS50100290A |
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JPS5096559A |
1461663 Preparing 17-esters of 17α,21-dihydroxy steroids LARK SpA 12 Nov 1974 [4 Jan 1974 (2)] 27543/74 Heading C2U A 17 - monoester of a 17α,21 - dihydroxy steroid is prepared by esterifying the corresponding 17α,21-dihydroxy steroid...
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JPS5096558A |
1461663 Preparing 17-esters of 17α,21-dihydroxy steroids LARK SpA 12 Nov 1974 [4 Jan 1974 (2)] 27543/74 Heading C2U A 17 - monoester of a 17α,21 - dihydroxy steroid is prepared by esterifying the corresponding 17α,21-dihydroxy steroid...
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JPS5084561A |
1494097 D - homo - 20 - keto - pregnanes SCHERING AG 25 Nov 1974 [30 Nov 1973 19 April 1974] 51006/74 Heading C2U Novel D-homo-steroids of the formula wherein R 1 is O, H(#-OR 5 ) or H(α-OR 5 ) in which R 5 is H or C 1-5 acyl, R 2 is H ...
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JPS5016439B1 |
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JPS5016438B1 |
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JPS5059361A |
Novel D-homosteroids of the formula are disclosed. The novel D-homosteroids exhibit anti-inflammatory activity and are useful intermediates for the synthesis of anti-inflammatory D-homosteroids.
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JPS5011998B2 |
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JPS5011912B1 |
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JPS5032157A |
Steroids bearing the substituent -X-NR1R2 wherein -NR1R2 is a tritium of carbon-14 labeled amino or amino-acid group and -X- is -R3-, -OCOR3-, =N-O-R3- or -NHCOR3- wherein R3 is -(CH2)nCO- in which n is 0-4, are useful as diagnostic agents.
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JPS502756B1 |
1,271,984. 7-Hydroxylated steroids. E. R. SQUIBB & SONS Inc. 28 Feb., 1969 [15 March, 1968], No. 10895/69. Heading C2U. [Also in Division C5] The invention comprises compounds of formula wherein R is H or acyl; P and Q are each H, C 1-8 ...
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JPS502755B1 |
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JPS505593A |
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JPS4946076B1 |
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JPS4946077B1 |
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JPS4946075B1 |
1302207 6-Hydroxy-steroids SCHERING AG 27 Jan 1970 [27 Jan 1969] 3929/70 Headings C2C and C2U 6-Hydroxy-3-keto-#4-steroids of the pregnane, testololactone and androstane series are prepared by the action of micro-organisms (or enzymes th...
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JPS4944346B1 |
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JPS4944345B1 |
1,184,287. Conversion of pregnanes to androstanes. F. HOFFMANN-LA ROCHE & CO. A.G. 3 Oct., 1968 [5 Oct., 1967], No. 46946/68. Heading C2U. C 17 -Oxygenated steroids of the androstane or 9#,10α-androstane series are prepared by subjectin...
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JPS49101591A |
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JPS4994894A |
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JPS4994895A |
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JPS4962692A |
The present invention relates to a microbiological method for producing 20beta-hydroxy-9-oxo-1,2,3,4,10,19-hexanor-5,9-seco-pregnan-
5-oic acid, an intermediate for known steroids, from 3beta, 20beta-dihydroxypregn-5-ene or 2beta, 20-dih...
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JPS4920774B1 |
Trihydroxypregnene-3,20-diones (I) and especially 11 beta, 17 alpha, 21-trihydroxy-15, 16 beta-methylene-pregnene (4)-(and pregna-1,4-diene)-3,20-dione, for use as anti-inflammatories. R6 and R9 independently are H, halogen, R17, R21 ind...
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JPS4950192A |
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JPS4916632B1 |
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JPS4911696B1 |
1,255,950. 18-Methylene steroids. CIBAGEIGY A.G. 20 Dec., 1968 [22 Dec., 1967; 25 Nov., 1968], No. 60763/68. Heading C2U. 18-Methylene steroids are prepared (1) by heating N-oxides of tertiary 18-aminomethyl steroids; or (2) by splitting...
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JPS4926487A |
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JPS4912096A |
1369179 Aza-steroidal antibiotics A-25822 ELI LILLY & CO 16 Feb 1973 [29 Feb 1972 2 Feb 1973] 7805/73 Heading C2A Novel antibiotic substances having an azasteroid structure and designated generally as A-25822 antibiotics are produced by ...
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