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JPS5758159B2 |
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JPS5749200B2 |
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JPS5742317B2 |
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JPS5741919B2 |
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JPS5741918B2 |
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JPS57138398A |
PURPOSE: A bacterium in Arthrobacter or Brevibacterium, capable of producing the titled substance, is cultured in an enriched medium containing cholic acid salt of less than specified concentration and the titled substance formed in the ...
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JPS5728558B2 |
The main sapogenins in the roots and rhizomes of Helleborous species are recovered by treating the roots and/or rhizomes or drugs or extracts made therefrom with cellulase, hemicellulase or beta -glucosidase.
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JPS578600B2 |
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JPS57500226A |
PCT No. PCT/AU81/00017 Sec. 371 Date Oct. 22, 1981 Sec. 102(e) Date Oct. 22, 1981 PCT Filed Feb. 13, 1981 PCT Pub. No. WO81/02427 PCT Pub. Date Sep. 3, 1981.This invention relates to a process for the fermentation of bile which includes ...
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JPS5722697A |
PURPOSE: To produce the titled substance in large amount, by carrying out plasmogamy of animal cells capable of producing a bioproducing substance such as insulin, interferon, etc. e.g. pancreatic Langerhans' islands B cell, leukocyte ce...
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JPS56169699A |
Novel halogenated steroids of the formula (A) in which X represents a halogen atom having a maximum atomic number of 17, Y represents a hydrogen atom or hydroxyl, and R represents an alkyl radical having a maximum of 6 carbon atoms, and ...
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JPS5645593B2 |
1461841 Enzymic reactions in biphasic aqueous-organic systems SNAMPROGETTI SpA and ISF SpA 4 Jan 1974 [26 Jan 1973] 00502/74 Headings C2U and C2C [Also in Division G1] Enzymic reactions using one or more of laccase, hydroxy-steroid dehyd...
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JPS56134997A |
PURPOSE: To improve the production of the titled substance, by cultivating a yeast having the ability to produce the titled substance by the sprinkling (spreading) or continuous culture method aerobically while controlling the specific g...
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JPS5642919B2 |
Mutants which are used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to 9 alpha -hydroxyandrostenedione (9 alpha -OH AD). 9 alpha -OH AD is a valua...
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JPS56127098A |
PURPOSE: To prepare a saponin derivative useful as a raw material of other compounds and known saponin compounds, by eliminting at least one saccharide from the substutuent at a specific position by the enzymatic hydrolysis of saponin, a...
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JPS56113798A |
A DELTA 1,4,17-BNC compound having the formula: wherein X is a substituent selected from the group consisting of OH and OCH3; as well as its process of production by microbiological side-chain splitting of a 17-C-side-chain steroid with ...
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JPS5699500A |
Novel corticoid 17-thioacetals of the formula: wherein X is hydrogen, fluorine or methyl, R1 is hydrogen or C1-C6 alkyl, and R2 is hydrogen or the acyl group of a C1-16 - hydrocarbon carboxylic acid, have valuable medicinal properties, e...
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JPS5685297A |
PURPOSE: To increase the production of ergosterol, remarkably, by culturing yeast in the copresence of a source of isoprenoid compound precursor and one or more compounds selected from acetoacetic acid esters and nonionic surface active ...
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JPS5658496A |
PURPOSE: To increase the amount of produced ergosterol remarkably in the preparation of ergosterol by the cultivation of yeast, by adding isopentenyl alcohol and polyphosphoric acids to the cultivation medium. CONSTITUTION: Yeast capable...
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JPS5651997A |
PURPOSE: To prepare 12-ketochenodeoxycholic acid, by subjecting dehydrocholic acid to the action of a microorganism belonging to the genus Lactobacillus. CONSTITUTION: A microorganism which belongs to the genus Lactobacillus and has the ...
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JPS5619237B2 |
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JPS5645500A |
This invention relates to a process for the preparation of a concentrate containing sterol compounds of natural origin, which concentrate is suitable as a starting material for the transformation of sterol compounds by fermentation, whic...
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JPS5632996A |
PURPOSE: To prepare and accumulate a specific secophenol in high concentration and yield from androsta-1,4-diene-3,17-dione(ADD), by culturing bacteria belonging to Rhodococcus genus in a medium containing ADD as a substrate. CONSTITUTIO...
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JPS5612440B1 |
1319127 Asymmetric reduction of secosteroids AMERICAN HOME PRODUCTS CORP 9 Sept 1970 [28 April 1970] 43095/70 Heading C2C An optically active d-13#-alkyl-17#-hydroxy- 8,14 - secogona - 1,3,5(10),9(11) - tetraen - 14- one is prepared by a...
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JPS56500336A |
The present invention concerns ergostadientriols which may be recovered from either the fungus R. oligosporus or the fungus R. oryzae as well as from soybeans which have been fermented with either of these fungi. Alternatively, the stero...
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JPS569320B2 |
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JPS5615692A |
PURPOSE: To produce 3,9β-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-17-one (DSA), by incubating a mutant of a microorganism belonging to the genus Mycobacterium in a culture medium containing sterols as a substrate. CONSTITUTION: A mu...
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JPS568399A |
A multi-step synthesis of chenodeoxycholic acid from 3-keto-bisnorcholenol, a compound readily obtained from the abundant plant sterol beta -sitosterol, is described. A key step in the synthesis is the stereoselective microbial introduct...
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JPS561917B2 |
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JPS561079B2 |
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JPS55150893A |
PURPOSE: A novel mutant that is obtained by mutating a microorganism belonging to Arthrobacter, thus permitting the accumulation of androstane compounds converted from sterol with no addition of inhibitor. CONSTITUTION: A mutant, which i...
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JPS55150891A |
PURPOSE: A fermentation tank for culturing microorganisms is provided with a plate scraper that slides on the inner wall of the fermentation tank to release the microorganisms sticking to the inner wall and recirculate them to the cultur...
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JPS55148099A |
Mutants which are used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to 9 alpha -hydroxyandrostenedione (9 alpha -OH AD). 9 alpha -OH AD is a valua...
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JPS55148083A |
PURPOSE: A mutant, capable of accumulating a large amount of androstane compounds, and belonging to the genus Nocardia. CONSTITUTION: A mutant, free from an enzyme for hydrolyzing androstane compounds, or of low activity, obtained by the...
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JPS5545192B1 |
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JPS5544598B2 |
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JPS55144880A |
PURPOSE: To prepare a reactor comprising a tube with an immobilized enzyme, by integrating a vinyl chloride resin with the inner wall of the tube as a carrier, and by supporting an enzyme on the carrier. CONSTITUTION: A vinyl chloride re...
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JPS55138394A |
PURPOSE: A mutant from Mycobacterium microorganism is cultured in a medium containing sterol as the substrate to collect androstane compounds formed. CONSTITUTION: A mutant that belongs to Mycobacterium diernhoferi and has lost the enzym...
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JPS5541756B2 |
1423034 Production of ergosterol and its esters TAKEDA YAKUHIN KOGYO KK 22 Jan 1973 [28 Jan 1972] 3196/73 Heading C2U A method for producing ergosterol and/or an ester thereof comprises cultivating a microorganism of the genus Trichoderm...
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JPS55127991A |
For the production of 17-C-steroid- alpha -propionic acid compounds by microbial side chain degradation on 17-C-side chain steroid substrates wild strain microorganisms selected in predetermined manner are subjected to a multi-stage muta...
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JPS55127995A |
PURPOSE: To produce 3β-hydroxy-23, 24-bisnorchola-5-en-22-oic acid, by incubating mutants of microorganisms belonging to the genus Rhodococcus. CONSTITUTION: Mutants of microorganisms, e.g. Rhodococcus corallinus MCI-1159 (FERM-P No.481...
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JPS5535117B2 |
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JPS55114296A |
The invention relates to a process for producing 7 alpha -hydroxylated steroids by fermenting or reacting a steroid to be hydroxylated with microorganisms of the genus Botryodiplodia or enzyme extracts thereof until hydroxylation occurs....
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JPS55111796A |
PURPOSE: To enable the production of androstane cpd. in large quantities efficiently, by a method wherein a mutant of a strain of Rhodococcus genus is cultivated in a medium contg. carbon source, nitrogen source and mineral source by usi...
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JPS5588699A |
PURPOSE: To obtain physiologically active substances, such as dechlorogriseofulvin, by extracting mycelia or a medium of culturing Coriolus vernicipes after cultivation with an organic solvent. CONSTITUTION: Coriolus vernicipes is cultur...
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JPS5585396A |
PURPOSE: To prepare an androstane compound by culturing a mutant of Mycobacterium vaccae in a medium containing a sterol as a substrate. CONSTITUTION: A mutant of Mycobacterium vaccae, wherein the androstane compound-decomposition enzyme...
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JPS5537121A |
PURPOSE: To prepare 1,2-dehydrotestosterone (17β-hydroxy-androsta-1,4-dien-3- one; DHT) in large quantity, by culturing microorganisms capable of producing androsta-1,4-diene-3,17-dione (ADD), under controlled aeration. CONSTITUTION: In...
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JPS552957B2 |
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JPS54138192A |
PURPOSE: To prepare androstane compounds useful as raw material of medicines, economically and in an industrial scale, by culturing a mutant belonging to Brevibacterium genus in a medium containing sterols as substrates, and separating a...
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JPS54101488A |
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