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JPS615715B2 |
A process for the preparation of 4-androstene-3,17-dione derivatives of the formula wherein X is 6,7-methylene or fluoro, chloro, or methyl in the 6- or 7-position, comprises fermenting a sterol of the formula wherein X is as above and R...
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JPS611440B2 |
The present disclosure relates to novel D-homo-pregnene steroids useful as progestational agents.
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JPS61356B2 |
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JPS6174B2 |
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JPS6058956B2 |
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JPS60258197A |
NEW MATERIAL:Compounds of formula I (R1 is O, OH; when R1 is O, R2 is H, OH; when R1 is OH, R2 is also OH), formula II and formula III. USE: A food additive for giving foods bitter taste such as a substituent of hops for beer. PREPARATIO...
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JPS60241897A |
1. Process for the manufacture of 15 alpha-hydroxy-4-androstene-3,17-dione by the microbiological hydroxylation of 4-androstene-13,17-dione characterised in that Penicillium stoloniferum CBS P 102, Penicillium melinii CBS P 30 or Fusariu...
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JPS6052160B2 |
1365469 D-homosteroids F HOFFMANNLA ROCHE & CO AG 29 March 1973 [29 March 1972] 15112/73 Headings C2U and C2C The invention comprises compounds of formula (wherein R6 is H, F, Cl or Me; R9 is H, F, Cl or Br; and R17 and R21 are each hydr...
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JPS6051662B2 |
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JPS6050800B2 |
The present disclosure relates to steroid carboxylic acids and derivatives thereof. More particularly, the disclosure is concerned with D-homosteroid carboxylic acids and their derivatives, a process for the preparation thereof and pharm...
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JPS6030517B2 |
Estrene-3,17-diones of the formula wherein X is oxo, or ketalized oxo, preferably alkylenedioxy of 2-6 carbon atoms or o-phenylenedioxy; DELTA IS A CARBON ATOM LINKED TO THE ADJACENT CARBON ATOMS BY A DOUBLE BOND AND TWO SINGLE BONDS; R1...
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JPS6029470B2 |
Mutants which are used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to 9 alpha -hydroxyandrostenedione (9 alpha -OH AD). 9 alpha -OH AD is a valua...
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JPS6024719B2 |
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JPS6024720B2 |
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JPS60100594A |
NEW MATERIAL:The compound of formula I (R is H or alkali metal) or its salt. USE: An agent for dissolving cholesterol gall stone. PREPARATION: Cunninghamella echinulate ST-22 strain (FERM-P No.7328) which is a mold belonging to Cunningha...
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JPS6019320B2 |
An improved process for isolating 3-hydroxy steroids and 3-keto steroids from mixtures thereof with lipids by dissolving the mixtures in an organic solvent, mixing the dissolved mixture with a metal salt to form insoluble adducts of the ...
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JPS6075297A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS608120B2 |
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JPS60994B2 |
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JPS602190A |
The invention relates to a method of converting a water-insoluble or substantially water-insoluble organic substrate under the influence of a water-soluble enzyme requiring a cofactor. The conversion is carried out in a micellar system, ...
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JPS5951277B2 |
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JPS5940440B2 |
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JPS59159794A |
PURPOSE: Steroid is converted with immobilized cells of tobacco plant. CONSTITUTION: Cells of tobacco plant, e.g., cells immobilized in a gel of calcium alginate, is cultured in a medium which is prepared by adding a plant growth regulat...
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JPS5937078B2 |
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JPS5926279B2 |
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JPS59501046A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS5988090A |
A biocatalyst contains microorganisms, e.g., of the species Arthrobacter simplex, Aspergillus ochraceus, Bacillus sphaericus, Curvularia lunata, Flavobacterium dehydrogenans, Mycobacterium spec., or Saccharaomyces uvarum, immobilized on ...
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JPS5913196B2 |
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JPS5910799B2 |
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JPS5910680B2 |
Anti-inflammatory D-homosteroids of the formula in which the dotted 1,2 bond denotes an optional C-C bond; R<6> denotes hydrogen, fluorine, chlorine or methyl; R<9> denotes hydrogen, fluorine or chlorine and R<17a> denotes hydroxyl or ac...
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JPS5910199B2 |
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JPS5910197B2 |
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JPS5910198B2 |
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JPS5851760B2 |
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JPS58179498A |
PURPOSE: To obtain the titled compound useful as a synthetic raw material for adrenal cortical hormone, in high efficiency, by converting a sterol compound through an androstane compound to 11α-hdroxylated androstane compound using micr...
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JPS5844360B2 |
1365469 D-homosteroids F HOFFMANNLA ROCHE & CO AG 29 March 1973 [29 March 1972] 15112/73 Headings C2U and C2C The invention comprises compounds of formula (wherein R6 is H, F, Cl or Me; R9 is H, F, Cl or Br; and R17 and R21 are each hydr...
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JPS58138396A |
PURPOSE: A mutant of a microorganism in Pseudonocardia is cultured in a medium containing sterol in the absence of any chemical inhibiting the oxidation of androstanes to produce androstanes. CONSTITUTION: A mutant in Pseudonocardia, e.g...
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JPS58138380A |
PURPOSE: To provide a microbial strain capable of accumulating an androstane compound in a large amount without addition of inhibiting agent, and consisting of a mutant of microbial strain belonging to Pseudonocardia genus and capable of...
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JPS58121800A |
PURPOSE: A specific bacterium in Pseudomonas brevis is cultured in a medium containing 3α, 7α-dihydroxy-5β-cholanic acid or its salt to produce the titled compound in high selectivity and yield. CONSTITUTION: A bacterium that produces...
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JPS5830039B2 |
A process for the production of a fraction enriched in cholesterol and cholesterol esters from the residues of the processing of fats, in which the residues in emulsified form in an aqueous culture medium are broken down with a microorga...
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JPS5886096A |
PURPOSE: To prepare 12β-hydroxyandrosta-1,4-diene-3,17-dione, in high selectivity and yield, by culturing microorganisms belonging to Aeromonas genus in a medium containing deoxycholic acid and/or its salt. CONSTITUTION: Microorganism b...
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JPS5863396A |
PURPOSE: To prepare the titled compound in high selectivity and yield, by cultivating a specific bacterium belonging to Pseudomonas ovalis in a culture medium containing deoxycholic acid (salt), and collecting the product. CONSTITUTION: ...
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JPS5863397A |
PURPOSE: To prepare the titled compound in high selectivity and yield, by cultivating a specific bacterium belonging to Pseudomonas stutzeri in a culture medium containing deoxychloic acid (salt), and collecting the resultant product. CO...
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JPS5856693A |
The subject invention concerns a novel fermentation process for making the novel useful steroid intermediate 9-hydroxy-3-oxo-4,17(20)-pregnadiene-20-carboxyaldehyde (I). This compound can be used as in the synthesis of valuable corticoids.
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JPS5851897A |
6-fluoro-9 alpha -hydroxyandrost-4 ene-3,17-diones, including the novel 6 alpha -isomer, are prepared by microbial degradation of the 6-fluoro- DELTA <4>-3- keto derivatives of sterols using a mutant microorganism selected from Arthrobac...
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JPS5836390A |
The invention relates to a process for carrying out an enzymatic reaction in which an enzyme containing aqueous phase in the form of a gel, especially gel spheres, is contacted with a solution of a substrate in a water-immiscible solvent...
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JPS5816695A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS584553B2 |
1 alpha -Oxysteroid of the formula wherein R1 is methyl or ethyl, R2 and R3 each are hydrogen or alkanoyl of 1-8 carbon atoms, and R4 is hydrogen or hydrocarbon of 1-4 carbon atoms, ARE PROGESTESTIONALLY ACTIVE AND USEFUL IN ORAL CONTRAC...
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JPS5758157B2 |
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JPS5758160B2 |
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