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WO/2017/038168A1 |
In a gate electrode (10A) used as a shutter gate, a pair of electroconductive securing members (131, 132) that are made of metal and have the same size are attached inside a rectangular opening (12) in a ceramic base (11), and ceramic in...
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WO/2017/037555A1 |
Systems and methods are provided for enabling or disabling a DMS device during an IDA method. Each cycle of the method includes a survey scan step, producing a precursor ion mass spectrum, and an MS/MS scan step. During the MS/MS scan st...
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WO/2017/039133A1 |
The present invention relates to a quadrupole mass filter for a quadrupole mass spectrometer, the quadrupole mass filter comprising four electrodes and an insulator holder for fixing the four electrodes. In the quadrupole mass filter acc...
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WO/2017/037563A1 |
A plurality of measured product ion spectra are produced using a DIA tandem mass spectrometry method for a sample of two or more known proteins. A desired confidence probability for the identification of at least one known protein of two...
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WO/2017/033087A1 |
A plurality of product ion spectra measured over plurality of cycles for each precursor ion mass selection window of two or more precursor ion mass selection windows are received from a tandem mass spectrometer. A product ion extracted i...
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WO/2017/032753A1 |
A system is described that is capable of operating as an energy conversion system that functions as a fuel cell and generates electrical current from a fuel or fuels, or as a reactor for conversion of starter materials into more complex ...
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WO/2017/034972A1 |
The present invention comprises novel methods of continuously monitoring the performance of an atmospheric pressure ionization (API) system. The methods of the invention allow for improved quality monitoring of the processes that leads t...
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WO/2017/033959A1 |
Provided is an atmospheric pressure ionization method which, when a sample is ionized in a mass spectrometer, enables protonated molecule or/and deprotonated molecule generating reaction of a sample starting from a Penning ionization rea...
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WO/2017/032503A1 |
A method for forming a miniature skimmer cone for a free jet expansion vacuum interface is disclosed. The skimmer cone is formed from electroplated metal, deposited inside a blind hole formed on a silicon substrate. The substrate is part...
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WO/2017/029201A1 |
The invention provides a mass spectrometer that comprises a collision cell having an axial electric field that enhances transmission of light ions, especially elemental ions, through the collision cell, relative to heavier ions. The inve...
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WO/2017/028838A1 |
The invention relates to a method for analysing a data set of a time-of-flight mass spectrometry measurement for the detection of intensity maximums in the form of peaks, wherein a time-of-flight of accelerated masses with charge is meas...
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WO/2017/029200A1 |
The present invention can be directed to a mass spectrometer, relevant parts thereof like replacement kits or upgrading kits and/or mass spectrometry methods. A mass spectrometer according to the present invention can comprise at least o...
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WO/2017/025892A1 |
An m/z range of an ion beam is divided into two or more precursor ion mass selection windows. A pattern of two or more different window m/z ranges to be used during two or more successive cycles for at least one precursor ion mass select...
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WO/2017/025205A1 |
The spraying device serves for spraying samples with a solution, wherein a liquid feed for the metered feeding of the solution and a gas feed are provided which are connected via supply lines to a nozzle head (10) which has a gas outlet ...
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WO/2017/021406A1 |
The invention relates to a method for operating an ion gate having at least a first, a second, and a third electrode, which are arranged one after the other in an intended drifting direction of ions to be influenced by the ion gate, in s...
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WO/2017/022125A1 |
This mass spectrometer is provided with a collision cell (16) disposed in a medium vacuum region, a focusing electrode (18), an accelerating electrode (19), a front-stage ion lens system (20) that is an electrostatic lens, a partition (2...
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WO/2017/016099A1 |
Provided are an ionization method and device. The ionization method comprises an ion source, a sample and a mass spectrum sample injection channel, and is characterized in that the ion source is flame. The ionization method, by using fla...
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WO/2017/017479A1 |
The disclosure relates to methods and apparatus for ion separation, for example using time of flight and ion mobility spectrometry. Ion shutters for use in IMS cells and to methods of operating them are also disclosed. The shutter includ...
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WO/2017/015700A1 |
The present invention provides an apparatus for generating and focussing electrons, the apparatus having an emissive material configured to emit an electron, an electron target, and an electrical potential gradient generating means confi...
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WO/2017/019852A1 |
Atmospheric pressure ion guides are provided. The atmospheric pressure ion guides can include a multi-ring electrode structure connecting a larger opening to a smaller opening and having a series of ring electrodes with decreasing diamet...
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WO/2017/013832A1 |
The present invention provides an ion guiding device, which comprises two sets of electrodes extending along a certain space axis, a first power supply device and a second power supply device; wherein the two sets of electrodes are expan...
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WO/2017/013609A1 |
Provided is a device used for mass spectrometer ionisation and ion introduction, said device comprising an ionisation source chamber at less than atmospheric pressure; at least one ionisation source, arranged within the ionisation source...
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WO/2017/010163A1 |
The present invention provides a shutter arranged so that, in order to open and close an opening formed in a partition dividing two spaces having a difference in pressure, the shutter moves along the high-pressure-side wall of the partit...
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WO/2017/011439A1 |
A method is disclosed of predicting cancer patient response to immune checkpoint inhibitors, e.g., an antibody drug blocking ligand activation of programmed cell death 1 (PD-1) or CTLA4. The method includes obtaining mass spectrometry da...
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WO/2017/006523A1 |
The present invention provides a mass spectrometer and a method applied thereby for reducing ion loss and succeeding stage vacuum load, and the mass spectrometer comprises an ion source connected via vacuum interfaces, a vacuum chamber a...
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WO/2017/007824A1 |
A system can include an exchangeable mounting structure having a visual marking or coloring and at least one physically associated sample introduction system component having an indicating mark or color matching the visual marking or col...
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WO/2017/003274A2 |
The invention relates to electronic analytical technology for determining the composition and the structure of substances, in particular in the field of analyzers comprising at least one mass spectrometer (MS), and can be used in medicin...
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WO/2017/002176A1 |
A vacuum device (1) is provided with a vacuum container (2), gas introducing section (4), heater (5), gas discharge section (6), and vacuum pump (7). A gas in an inflow pipe of the gas introducing section (4) is introduced into the vacuu...
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WO/2017/002936A1 |
A charged particle detector (1) according to an embodiment of the present invention is provided, in a configuration in which a micro channel plate (MCP) (10) having a bias angle and a PD (80) are combined, with the MCP and the PD dispose...
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WO/2017/004197A1 |
An AC coupler for transmitting high-frequency components of a wideband signal includes a signal conductor and a shielding structure arranged as a transmission line. The signal conductor includes a conductive element and a capacitor confi...
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WO/2016/210307A1 |
Systems and methods are described to determine whether a sample transmitted through a transfer line from a remote sampling system contains a suitable sample to analyze by an analysis system. A system embodiment includes, but is not limit...
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WO/2016/203328A1 |
One or more known compounds of a sample are ionized. At least one precursor ion corresponding to a compound of the one or more known compounds is selected and fragmented, producing a product ion mass spectrum for the precursor ion. An m/...
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WO/2016/200099A2 |
The present invention relates to a method for examining human saliva by using sugar chains specific to human saliva. Mass spectrometry was performed by using N-glycan isolation and purification on human body fluids including human saliva...
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WO/2016/198984A1 |
Systems and methods prevent potentially convolved precursor ion peaks from being excluded in subsequent cycles of an IDA experiment so that additional product ion data is collected. A sample is ionized producing an ion beam. A plurality ...
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WO/2016/201253A1 |
Embodiments related to the use and production of porous carbon materials in ion emitters and other applications are described.
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WO/2016/193699A1 |
A method of mass spectrometry is disclosed comprising detecting the ions transmitted by a mass filter (4) with a detector (6); changing the RF and/or DC voltage applied to the mass filter (4) during a voltage transition period so as to c...
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WO/2016/196432A1 |
Techniques for performing data acquisition and analysis are described. A multi-mode acquisition strategy may be performed which iteratively selects mass isolation windows of different sizes in different scan cycles to acquire experimenta...
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WO/2016/193701A1 |
A mass filter is disclosed having at least one electrode (42-48) comprising an aperture (43) or recess. Voltages are applied to the electrodes (42-48) of the mass filter such that ions having mass to charge ratios in a desired range are ...
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WO/2016/196181A1 |
The present disclosure relates generally to metabolomics and lipidomics, and to the analysis of metabolite and lipids in simple and complex mixtures. More specifically, the present disclosure relates to a mass spectrometry system using d...
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WO/2016/193721A1 |
A method of calibrating or optimising an analytical instrument is disclosed that comprises analysing analyte from a sample using an analytical instrument, determining a sample type of the sample based on analysis of analyte from the samp...
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WO/2016/196125A1 |
A method for organism identification using MALDI TOF mass spectrometry includes generating a searchable database. A mass spectrum is acquired from a sample. Peak detection of the acquired mass spectrum is performed, binned and a vector i...
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WO/2016/191451A1 |
Certain configurations of devices are described herein that include a DC multipole that is effective to doubly bend the ions in an entering particle beam. In some instances, the devices include a first multipole configured to provide a D...
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WO/2016/189334A1 |
A method of mass spectrometry is disclosed comprising digitising a signal output from a detector to provide a first digitised signal. A finite impulse response ("FIR") filter, a digital filter or an echo cancellation filter is applied to...
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WO/2016/184252A1 |
A mass spectrometry device and analysis method for a gas phase molecule-ion reaction. The device comprises a reaction gas introduction device (201) and a gas phase molecule-ion reaction mass spectrometry analysis device, wherein the reac...
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WO/2016/185108A1 |
Method for identifying by mass spectrometry an unknown microorganism subgroup from among a set of reference subgroups, comprising a step of constructing a knowledgebase and a model allowing classification by associated subgroup, which st...
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WO/2016/182563A1 |
[00212] An electrospray ionization (ESI)-mass spectrometer analysis systems include an ESI device with at least one emitter configured to electrospray ions and a mass spectrometer in fluid communication with the at least one emitter of t...
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WO/2016/181167A1 |
A method of mass and/or ion mobility spectrometry is disclosed that comprises accumulating ions for a first period of time (T1) one or more times so as to form one or more first groups of ions, accumulating ions for a second period of ti...
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WO/2016/181299A1 |
Systems and methods described herein can provide for "top down" mass spectrometric analysis of proteins or peptides in a sample using ExD, in some aspects via direct infusion of the sample to the ion source without on-line LC separation,...
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WO/2016/181908A1 |
Provided are: a sample plate for mass spectrometric analyses which does not necessitate the use of a matrix in combination therewith, is less apt to decrease in ionization-assisting effect with the lapse of time, is reduced in in-plane u...
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WO/2016/177810A1 |
The invention relates to a method for analysis by mass spectrometer of liquid and/or gaseous samples and to a device (1) for carrying out said method. A a mass spectrometer (29) is used which has a first flow element (19) for liquid samp...
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