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WO/2016/177503A1 |
The invention relates to a method for examining a gas (4) by mass spectrometry, comprising: ionizing the gas (4) for producing ions (4a, 4b), and storing, exciting and detecting at least some of the produced ions (4a, 4b) in an FT ion tr...
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WO/2016/177164A1 |
The present invention relates to the field of mass spectrometers and ion mass analysis. Disclosed are a networked mass analysis method and device. The device comprises: an ion source for generating ions to be detected; an ion transporter...
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WO/2016/177812A1 |
One aspect of the invention concerns a method for characterising ions comprising: - a step according to which a plurality of first-generation ions is trapped in an ion trap; - a step according to which the plurality of first-generation i...
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WO/2016/178033A1 |
Methods, systems and computer-readable media for identifying a sample mixture based on relative isotope ratios for a plurality of compounds in the sample mixture by correlating a set of three of more relative isotope ratios for a sample ...
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WO/2016/178103A1 |
In one aspect, a mass spectrometer is disclosed, which comprises an ion source for generating ions, a chamber comprising a curtain plate providing an inlet orifice for receiving at least a portion of said generated ions, and a deflection...
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WO/2016/178029A1 |
A method of mass spectrometry is disclosed comprising passing ions to an oversampled Time of Flight mass analyser (4) and sequentially recording ion signals on a plurality of different channels (51, 52) to obtain a plurality of first ove...
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WO/2016/174545A1 |
A quadrupole is filled with ions and the ions are cooled by applying a pressure and gas flow within the quadrupole. Ions are trapped in the quadrupole by applying a DC voltage and an RF voltage to quadrupole rods of the quadrupole, one o...
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WO/2016/174462A1 |
A method of time-of-flight mass spectrometry is disclosed comprising: providing two ion mirrors (42) that are spaced apart in a first dimension (X-dimension) and that are each elongated in a second dimension (Z-dimension) orthogonal to t...
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WO/2016/173786A1 |
A circuit for generating a voltage waveform at an output node. The circuit includes a first voltage rail configured to be held at a first voltage, wherein the first voltage rail is connected to the output node via a first voltage rail sw...
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WO/2016/174990A1 |
A mass spectrometer (11) according to the present invention, in order to control ion transmittance (sensitivity), comprises an ion source (2) that ionizes a sample, an ion guide (3) that comprises at least four rod-shaped electrodes and ...
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WO/2016/171768A1 |
A unique fiber core sampler composition, related systems, and techniques for designing, making, and using the same are described. The sampler is used to interface with existing field instrumentation, such as Ion Mobility Spectrometer (IM...
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WO/2016/171182A1 |
An analysis method is a method for quantitatively analyzing a component contained in skin, and comprises the steps of: supplying a predetermined amount of an internal standard substance containing a compound that is labeled with a stable...
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WO/2016/172215A1 |
Disclosed herein is a method of generating a high resolution image of a cellular sample, the method including i) labeling a cellular sample with at least one mass tag, thereby producing a labeled sample in which a biological feature of i...
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WO/2016/170272A1 |
The invention relates to a device for characterizing a high-power laser beam, characterized in that it comprises: - a platen (1) partially bounding at least one propagation space of the laser beam (LP) to be characterized, comprising an ...
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WO/2016/170371A1 |
A method is disclosed comprising: trapping ions in an ion trap(40); applying a first force on the ions within the ion trap in a first direction, said force having a magnitude that is dependent upon the value of a physicochemical property...
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WO/2016/168391A1 |
The present disclosure relates to structural elucidation of isotopically labeled analytes using chromatography-MS and data-independent acquisition. The present disclosure can be used for rapid screening of analytes, such as the metabolom...
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WO/2016/163385A1 |
The present invention addresses the problem of providing a laser microdissection apparatus having good operational efficiency. The problem can be resolved by means of a laser microdissection apparatus which includes: a sample moving mean...
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WO/2016/162658A1 |
A time of flight ("TOF") mass spectrometer having: an ion source; a detector; a variable voltage unit; a control unit. The control unit is configured to control the TOF mass spectrometer to perform at least one acquisition cycle that inc...
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WO/2016/164764A1 |
A system for sampling a sample material includes a device for directing sample into a capture probe. The device for supplying sample material to the probe can be a device for radiating energy to the surface to eject sample from the sampl...
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WO/2016/164004A1 |
Methods and apparatus of adding propellant to a thruster assembly are described. A first end of a beaker is disposed in an opening of the tank, where the beaker contains propellant and the first end of the beaker includes a breakaway bot...
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WO/2016/160835A1 |
Among other things, we describe methods and apparatus for the ionization of target molecular analytes of interest, e.g., for use in mass spectrometry. In some implementations, a thin molecular stream is emitted in either single or a spli...
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WO/2016/157030A1 |
Systems and methods described herein utilize an ion guide for use in mass spectrometer systems, which ion guide can receive ions from an ion source for transmission to downstream mass analyzers, while preventing debris (e.g., unsolvated ...
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WO/2016/159564A1 |
The present invention relates to a sample pretreatment system for separating, from a sample, and collecting carbon dioxide in order to perform radiocarbon dating using AMS, the system comprising: a plurality of sample pretreatment appara...
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WO/2016/160741A1 |
The present disclosure is directed to methods reagents and kits for solid phase extraction, derivatization with crown ether containing derivatizing agents, and mass spectrometry of the derivatized analytes.
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WO/2016/158380A1 |
While processing a distal end of a capillary 14 into an acute angle: an electrophoresis liquid passing hole 42 through which an electrophoresis liquid 16 can pass is opened in a flexible insulating plate 40; an electrodialysis membrane 4...
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WO/2016/157032A1 |
Systems and methods described herein utilize a multipole ion guide that can receive ions from an ion source for transmission to downstream mass analyzers, while preventing unwanted/interfering/contaminating ions from being transmitted in...
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WO/2016/154958A1 |
An accelerator mass spectrometry (AMS) device for simultaneously measuring isotopes comprises a sputtering anion source (1) for generating anions. The sputtering anion source (1) is connected to an accelerating tube (7) for simultaneousl...
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WO/2016/153819A1 |
A method of analyzing a population of cells is disclosed. In certain embodiments, the method includes i) obtaining an array of cells on a substrate, wherein the cells are labeled with one or more mass tags and are separated from one anot...
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WO/2016/150875A1 |
An apparatus for mass spectrometry comprises a portion generator (10) for creating localized analyte portions in synchronization with trigger pulses, a transfer system (20) coupled to the portion generator (10) for transporting the local...
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WO/2016/146508A1 |
According to an aspect of the invention, there is provided a method of accumulating ions in an ion trap having a first part (p1) and a second part (p2), the first and second parts being separated by a central electrode, said method compr...
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WO/2016/149658A1 |
A dual-ionization mass spectrometer includes a first mass spectrometer module forming a hard ionization mass spectrometer, a second mass spectrometer forming a soft ionization mass spectrometer, a vacuum ultraviolet light source position...
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WO/2016/146255A1 |
According to the invention, a target (1), on which the object to be examined is to be applied, is coated with multiple different matrix grids (2, 3) each offset from one another. At least one analysis grid is separately measured for each...
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WO/2016/142674A1 |
A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing an...
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WO/2016/145458A1 |
A multi-beam apparatus for observing a sample with high resolution and high throughput is proposed. In the apparatus, a source-conversion unit changes a single electron source into a virtual multi-source array, a primary projection imagi...
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WO/2016/142681A1 |
A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population;...
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WO/2016/142683A1 |
A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte201;supplying a matrix204 compound to said analyte 201 such that saidanalyte 201 dissolves in saidmatrix204; formingfirst dropletsof ...
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WO/2016/145041A1 |
The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and...
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WO/2016/142669A1 |
A method is disclosed comprising obtaining physical or other non-mass spectrometric data from one or more regions of a target using a probe (20). The physical or other non-mass spectrometric data may be used to determine one or more regi...
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WO/2016/142686A1 |
An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device (31) arranged and adapted to generate aerosol, smoke or vapour from a target and one or more second devices (34,35) arranged and a...
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WO/2016/142690A1 |
An apparatus is disclosed comprising a first device (1) for generating aerosol, smoke or vapour (5) from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer,the inlet conduit having an inlet through ...
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WO/2016/142692A1 |
A method of spectrometric analysis comprises obtaining one or more sample spectra for an aerosol, smoke or vapour sample. The one or more sample spectra are subjected to pre-processing and then multivariate and/or library based analysis ...
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WO/2016/142685A1 |
An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped,coil- shaped, helical or spiral-shaped collision assembly; and a ...
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WO/2016/145331A1 |
A method for mass spectral analysis of a sample containing a plurality of biomolecule species comprises: (a) mass analyzing a plurality of first-generation ion species generated from a sample portion; (b) automatically recognizing, for e...
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WO/2016/141733A1 |
The present invention relates to the technical field of mass analysis instruments. Disclosed is an ion excitation method in a linear ion trap. The method comprises: in a linear ion trap, and at an ion collision-induced dissociation stage...
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WO/2016/142679A1 |
A method is disclosed comprising obtaining or acquiring chemical or other non- mass spectrometric data from one or more regions of a target (2) using a chemical sensor (20). The chemical or other non-mass spectrometric data may be used t...
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WO/2016/142863A1 |
A method and apparatus for improving the quality of spectra of a sample obtained from a tandem mass spectrometer system containing an ion trap. The method and apparatus includes the setting of an upper and lower threshold limit on peak i...
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WO/2016/145390A1 |
The presently disclosed subject matter provides methods for analyzing complex mixtures with ultra high resolution mass spectrometry. In particular, the presently disclosed subject matter provides methods for identifying and monitoring th...
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WO/2016/142689A1 |
A method of analysis using mass and/or ion mobility spectrometry or ion mobility spectrometry is disclosed comprising: using a first device to generate aerosol, smoke or vapour from one or more regions of a first target of biological mat...
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WO/2016/142675A1 |
A method is disclosed comprising obtaining or acquiring image or other data from one or more regions of a target (2) using an imaging sensor (20). The image or other data may then be used to determine one or more regions of interest of t...
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WO/2016/144628A1 |
A system and method for characterizing incident ions are provided. The method includes positioning a transmission line detector to receive incident ions, the transmission line detector comprising a superconducting meandering wire definin...
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