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WO/2023/275241A1 |
The present invention refers to hyaluronic acid crosslinked with polyglycerol polyglycidyl ether containing local anesthetic agents, to a process for its preparation and its use in therapy, cosmetics and as a carrier.
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WO/2022/247930A9 |
Compositions and methods involving microspheres composed of mesenchymal cells such as dermal papilla cells (DPCs) and extracellular matrix, epithelial cell such as keratinocyte are disclosed. It has been discovered that by balancing the ...
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WO/2023/277235A1 |
The present invention relates to a human body plastic implant having an integrated radial silicone cell structure, and a manufacturing method therefor and, more specifically, to a human body plastic implant having an integrated radial si...
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WO/2023/278290A1 |
A prosthesis for reconstruction and/or augmentation of an anatomical shape. The prosthesis may have a three-dimensional configuration to reconstruct and/or augment the anatomical shape of a human breast. The prosthesis may be configured ...
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WO/2023/277426A1 |
An implant fixture for reducing periodontitis is disclosed. The implant fixture for reducing periodontitis according to an embodiment of the present application may comprise a body part which is implanted in bone tissue and forms an arti...
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WO/2023/275821A1 |
The invention relates to a method for decellularizing a tissue and/or organ that comprises immersing an isolated tissue and/or organ in an enzyme solution and a step of irradiating the tissue with ionizing electromagnetic radiation. The ...
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WO/2023/272355A1 |
The present invention relates to methods for providing a mineral or mineral-composite film, the method comprises the steps of: providing a layer comprising a calcium-based mineral, wherein the layer is produced using convective self-asse...
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WO/2023/275278A1 |
The present invention relates to a dermal filler composition based on crosslinked hyaluronic acid, wherein the hyaluronic acid is crosslinked with a high molecular weight polyethylene glycol diglycidyl ether (PEGDE) crosslinker having an...
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WO/2023/278654A1 |
An arthroscopic system for the repair of a ruptured anterior cruciate is provided. Aspects of the invention include a scaffold attached by a suture to an fixation device and inserted into a repair site via arthroscopic equipment. The sca...
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WO/2022/270932A1 |
The present invention relates to a composition for culturing chief cells isolated from living tissues or organs, particularly the stomach, and a method for culturing cells using the composition.
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WO/2022/269214A1 |
The present invention relates to a process for consolidating a hydrogel comprising alginate and gelatin, which includes a step of consolidation by crosslinking of the hydrogel using a suitable solution, in order to give it particularly a...
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WO/2022/272090A1 |
A hydrogel composition comprising an interpenetrating polymer network containing a natural polymer and two synthetic polymers polymerizable by a UV initiator to facilitate molding of visual implant devices is provided. The hydrogel compo...
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WO/2022/269215A1 |
The present invention relates to three-dimensional body implants comprising a hydrogel comprising crosslinked alginate and gelatin, and in particular breast implants. The hydrogel of the implants according to the invention may further co...
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WO/2022/081670A9 |
An implantable mesh device includes a surface layer on at least a portion thereof. The surface layer includes a plurality of extending members that mechanically interact with microbiota to disable the microbiota.
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WO/2022/268871A1 |
The invention proposes a method for preparing a cross-linked material, comprising forming amide bonds that conjugate one or more fibroin moieties with one or more polysaccharide moieties. The invention further relates to a cross-linked m...
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WO/2022/271255A1 |
Described are scaffolds for tissue engineering and method of making and using the scaffold. The method of making can include providing a textile layer formed of a plurality of yarns, wherein the plurality of yarns are formed of interlock...
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WO/2022/267093A1 |
Disclosed is a reactive oxygen-responsive degradable polyurethane cardiac patch for myocardial infarction repair, and a preparation method therefor. The cardiac patch comprises a cast membrane, an electrospun fibrous membrane and a porou...
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WO/2022/269601A1 |
A tissue culture vessel including a graft support tray (200) and a box having a lid (400) and a base which engages and retains the tray. The tray has two operational states: a first operational state in which a floor of the tray is sligh...
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WO/2022/272082A1 |
A corneal onlay device comprising a flat or flat-like base and a dome- shaped top, and having a water content ranging from about 78% to about 92% (w/w) inclusive. The corneal onlay device can be used to treat, for example without limitat...
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WO/2022/272189A1 |
Devices are disclosed for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the mitral valve and an edge to edge device. Methods are disclosed for reduc...
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WO/2022/270549A1 |
There has been demand for an additional method for producing antibodies. The present invention provides: a polymer-coated crosslinked alginate gel fiber in which a core layer containing a crosslinked alginate gel and either antibody-prod...
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WO/2022/269431A1 |
The present invention relates to a putty-type bone filler with a demineralised bone matrix (DBM) encapsulation in a polymer mixture. The formulation comprises a mixture of polymethyl methacrylate (PMMA), which is chemically activated by ...
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WO/2022/265098A1 |
In the reconstruction of a lost pinna, an implant-type regenerative medicine is performed. In this case, a skeletal structure using a bioabsorbable material has been proposed as a cell scaffold material. However, a skeletal structure tha...
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WO/2022/263778A1 |
The present invention relates to a removable implantable device intended for the production of articular cartilage, comprising: • a first support portion (2) made of biocompatible material, • a second support portion (3) made of bioc...
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WO/2022/265527A1 |
A process for the preparation of an extracellular matrix formulation (adipoECM) is disclosed using rapid adipose tissue decellularization to reduce the time of preparation to 2 days. The resulting formulation containing adipoECM may be u...
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WO/2022/262012A1 |
A chemically cross-linked hyaluronic acid hydrogel, a preparation method therefor, and an application thereof. The hyaluronic acid hydrogel is obtained by cross-linking hyaluronic acid or a salt thereof in a lithium bromide solution by u...
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WO/2022/265464A1 |
An artificial knee joint according to an embodiment of the present disclosure comprises: an upper joint member configured so as to be fixed to the human body and formed to allow a first shaft to pass therethrough; a body portion formed t...
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WO/2022/263601A1 |
The invention relates to a three-dimensional cellular microcompartment or an assembly of three-dimensional microcompartments of ovoid, cylindrical, spheroid or spherical shape, or substantially ovoid, cylindrical, spheroid or spherical s...
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WO/2022/264617A1 |
A ceramic biological material according to one aspect is composed of a sintered body comprising silicon nitride and a sintering aid and having flexural strength of 1196 MPa or more. This ceramic biological material may contain silicon ni...
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WO/2022/265585A1 |
A method of fabricating an implantable construct for a subject. The method comprises the step of providing a scaffold having a porous matrix, the scaffold being biocompatible to the subject; coating the scaffold with a plurality of pepti...
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WO/2022/262509A1 |
Disclosed in the present application are a leptin receptor affinity peptide and the use thereof. The sequence of the leptin receptor affinity peptide is as shown in SEQ ID NO. 1. Further disclosed in the present application is an affinit...
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WO/2022/266119A1 |
A sealing member for an implantable prosthesis includes a substrate comprising a substrate material, and one or more hydrogel structures disposed on an outwardly facing surface of the substrate. The hydrogel is stimulus responsive, and u...
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WO/2022/265327A1 |
The present invention relates to a tolerance deviation correction method using lamination and, more specifically, to a tolerance deviation correction method using lamination, the method comprising: a casting step of casting an implant by...
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WO/2022/265604A2 |
The invention relates to the air abrasion powder that consists of substances with bioactive, osteogenic and antibacterial activity such as calcium phosphate compounds, nano-titanium and boron compounds in nanoparticle structure, and part...
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WO/2022/265380A1 |
The present invention relates to a hyaluronic acid cross-linked product and a filler composition comprising same and, more particularly, to a hyaluronic acid cross-linked product having reduced swelling while having high cohesive and adh...
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WO/2022/265705A1 |
Disclosed are Self-Gelling materials and structures or materials or structures having one or more self-gelling components that overcome existing gel limitations due to hydrogel localization for medical applications by providing, for exam...
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WO/2022/261326A1 |
Disclosed are compositions comprising chitin nanofibers (ChNF) and silver chitosan (AgCh) and/or silver-copper chitosan (AgCuCh). Also disclosed are methods of coating various substrates with the disclosed compositions in order to impart...
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WO/2022/261164A1 |
A biocompatible seed for implantation in tissue of a patient includes an elongated body sized and shaped to be at least partially inserted into the tissue of the patient, in which the body includes a negative Poisson's ratio (NPR) materi...
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WO/2022/261058A1 |
Described herein are methods for providing the pulsed delivery of a 5HT2A agonist to a subject upon administration of a device to the subject. The device is composed of biodegradable polymers such that when administered to the subject, t...
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WO/2022/260583A1 |
The present invention relies on the discovery that certain proteins are enriched in the tumor microenvironment of different types of tumors and subgroups of tumors but not in others and that such proteins can be used as components of bio...
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WO/2022/259731A1 |
The present invention provides a base material for a pure titanium screw or a pure titanium screw which has sufficient strength comparable to those of titanium alloys. The present invention provides a substantially cylindrical pure titan...
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WO/2022/257915A1 |
Provided in the present invention are an amorphous alloy and the use thereof. Specifically, the amorphous alloy is composed of Zr aCu bAl cAg dTi eNb f, wherein a, b, c, d, e and f represent the mass percentages of each element, respecti...
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WO/2022/260988A1 |
A bioink for extrusion-based printing includes an extracellular matrix (ECM) precursor comprising an uncrosslinked polymer, and sacrificial microparticles dispersed in the ECM precursor. The sacrificial microparticles have a melting temp...
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WO/2022/261248A1 |
The present disclosure is directed to viable bioengineered allogeneic cellularized construct.
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WO/2022/260612A2 |
The invention is related to a method (100) of obtaining a setting solution that increases the mechanical strength of bone cements used in bone defects and bone fractures by incorporation of eggshell membrane protein or different proteins...
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WO/2022/254312A1 |
The present disclosure relates generally to a tissue graft capable of undergoing angiogenesis, comprising at least one self-assemble peptide and at least one endothelial cells. The present disclosure further relates to a method of prepar...
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WO/2022/256291A1 |
The technology described herein is directed to compositions, kits, combination, and hydrogels comprising a hydrogel scaffold and at least one of a loading liquid (e.g., an ionic liquid) and a drug. Further described herein are methods of...
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WO/2022/255650A1 |
The present invention relates to a carbon material implant and a method for manufacturing same and, particularly, to a carbon material implant manufactured by using a carbon sheet, and a method for manufacturing same. The method for manu...
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WO/2022/256401A1 |
A xenogeneic neural or nerve tissue from a non-wildtype, genetically reprogrammed non-human animal for xenotransplantation into a subject in need of neural or nerve tissue replacement, reconstruction, and/or repair, wherein the xenogenei...
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WO/2022/253478A1 |
The invention relates implants (1) comprising at least one biodegradable support structure (2) and at least one covering material at least partially covering the at least one biodegradable support structure (2) already prior to implantat...
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