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WO/2022/177551A1 |
Prosthetic heart valves having a conical shaped base valve structure formed from collagenous mammalian tissue. The base valve structure includes a plurality of elongated ribbon members that are positioned proximate each other in a joined...
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WO/2022/177234A1 |
Disclosed is an artificial implant comprising: a silicone shell; and a filler filling the interior of the shell, wherein at least a portion of the shell is a rupture-prevention part comprising two or more silicone layers and one or more ...
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WO/2022/175319A1 |
The present invention provides cationic peptoid / N-substituted peptidic copolymers, and pharmaceutical compositions thereof, as described generally and in subclasses herein, which compounds are useful for the treatment of microbial infe...
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WO/2022/171431A1 |
The present invention relates to a method for producing a sliding surface element based on UHMWPE for a joint endoprosthesis, comprising the steps of: - mixing UHMWPE in powder form with 0.09 to 0.11 wt.% of an antioxidant; - compressing...
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WO/2022/173780A1 |
Described herein are cords (or sutures) and methods for using cords wherein the cords comprise a synthetic aromatic polyamide (or aramid) polymer, wherein the cords comprise a core of a high-strength material such as a polymer (e.g., PET...
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WO/2022/170820A1 |
Disclosed is a 3D printing forming method for a bionic composite scaffold for synchronously repairing soft and hard tissue defects, which relates to the technical field of composite scaffolds. The bionic composite scaffold of the present...
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WO/2022/173066A1 |
The present invention relates to an acellular skin substitute for breast reconstruction and a preparation method therefor. In the present invention, an acellular skin substitute may be prepared through the removal of epidermal layers and...
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WO/2022/174077A1 |
Described herein are methods and compositions for promoting regeneration of nucleus pulposus with high osmolality, highly negative glycosaminoglycans, e.g., chondroitin sulfate (CS) or chondroitin sulfate proteoglycan (CSPG). The composi...
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WO/2022/172930A1 |
Provided is a novel device (transplantation device). The transplantation device is either (1) or (2). (1) A transplantation device containing a material (A) having a density of 12 mg/cm3 or higher, and having a dissolution rate of 80% ...
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WO/2022/174027A1 |
Glenoid implants, used in shoulder reconstruction or replacement surgery include a main body having an articulation surface configured to interface with the humeral head and having an anchoring surface opposite the articulation surface; ...
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WO/2022/172929A1 |
Provided is a novel device (transplant device) that contains gelatine. The transplant device is formed using a bioabsorbable non-woven fabric containing gelatine.
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WO/2022/173405A1 |
The invention relates to a biocompatible new generation titanium-based biocomposite tissue scaffold that exhibits low elastic modulus (E) and sufficient mechanical properties, as an alternative to the biomaterials used in the body, and t...
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WO/2022/169358A1 |
The invention is directed to a porous osteoinductive composite comprising osteoinductive granules embedded in a porous matrix, wherein more than 5% of the surface area of the osteoinductive granules is exposed from said matrix as determi...
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WO/2022/167436A1 |
A method of controlling at least one tribological property of a gel (3) comprising one or more crosslinked polymers, the method comprising the steps of providing at least one source of molecular oxygen (1) that is interfaced with a react...
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WO/2022/169620A1 |
The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The orthopedic implant also includes a porous coating secured to an ...
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WO/2022/166408A1 |
The present invention relates to a bioactive composite material for bone and a preparation method therefor and use thereof. Disclosed is a composite material for bone, characterized in that the composite material for bone comprises a sub...
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WO/2022/166964A1 |
An injectable antibacterial polymer hydrogel, a preparation method for same, and uses thereof. The hydrogel is prepared with an alginate, a hyaluronate, an iron ion-containing compound, and ethylenediaminetetraacetic acid disodium servin...
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WO/2022/168984A1 |
The purpose of the present invention is to provide a means for preventing and treating pancreatic fistula. The present invention achieves the foregoing by providing: a sheet-shaped cell culture for covering a cut surface of the pancreas,...
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WO/2022/167956A1 |
An apparatus includes an electrode configured to be implanted on or within a recipient's body. The electrode includes a first portion having a surface configured to be in electrical communication with the recipient's body and a second po...
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WO/2022/162256A1 |
Disclosed is a modular device for nerve regeneration, based on a hybrid structure comprising materials of natural and/or synthetic origin and a source of glial support cells (12), the structure being formed by one or more variable-length...
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WO/2022/164776A1 |
The invention relates to calcium hydroxyapatite particles having been sintered at a certain temperature range and which are not treated at a temperature above this range. Furthermore, the present invention relates to an injectable compos...
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WO/2022/161895A1 |
The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, special polymerized compounds, and special monomer compounds being particularly suitable for compositions an...
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WO/2022/164858A1 |
Systems and methods are provided for producing a product of cells organized into a desired macroscopic three-dimensional structure from one or more cell types with engineered donor and receptor pairs and optional scaffolds. Control over ...
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WO/2022/162542A1 |
The process for treating the surface of an implant made of titanium or its alloys comprises the successive steps of: treating this surface with laser radiation coming from a nano- or femtofiber laser source, in such a way that the surfac...
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WO/2022/160518A1 |
The present invention belongs to the fields of material science and biomedical materials, and specifically relates to an injectable, moldable and printable granular hydrogel material crosslinked by non-covalent and covalent bonds, a prep...
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WO/2022/164277A1 |
Disclosed are a patch comprising a metal-organic framework, in particular a silicone patch comprising a metal-organic framework and a silicone composition, and an artificial skin comprising a metal-organic framework. The patch and artifi...
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WO/2022/161993A1 |
The invention provides a process for producing acellular implants from a matrix material of non- human animal origin by decellularizing a matrix material to generate an acellular matrix, oxidizing the acellular matrix by treatment of the...
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WO/2022/164336A1 |
The present invention relates to the field of pharmacy, clinical or experimental medicine or veterinary medicine, and particularly to a method of producing non-toxic gels based on modified carboxymethylcellulose by reaction with modifyin...
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WO/2022/162091A1 |
26 ABSTRACT There is provided a method for producing fluorapatite crystals, the method comprising the steps of: a) providing a first aqueous solution comprising a phosphate source and a fluoride source, said first aqueous solution being ...
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WO/2022/162260A1 |
The present invention refers to a printing process of 4D prosthetic-type biomedical devices based on the polylactic acid and bioceramic combination with the incorporation of graphene family materials. These devices have properties that c...
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WO/2022/164052A1 |
The present invention relates to an artificial duct and a method for producing same, more specifically to a helical artificial duct that is flexible, and a method for producing same.
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WO/2022/162556A1 |
The present invention concerns a process for producing an intra-articularly injectable polynucleotide-based viscous gel, wherein said polynucleotides advantageously have an average molecular weight ≥ 1000 kDa, in particular selected in...
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WO/2022/164146A1 |
The present specification discloses an artificial dental root, and a method for manufacturing the artificial dental root by 3D printing.
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WO/2022/163872A1 |
Provided is a composition for promoting the regeneration of nucleus pulposus of intervertebral disc, said composition comprising a monovalent metal salt of a low endotoxin alginic acid and mesenchymal stem cells. In particular, the compo...
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WO/2022/159934A1 |
Disclosed herein are novel methods of processing reproductive tissue, from e.g., spay and neuter procedures, to optimize cell yield and viability in a manner suitable for obtaining multiple therapeutic doses typically required for clinic...
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WO/2022/157345A1 |
The present invention is directed to materials compatible with blood, implantable devices comprising said material, methods of preparation of such material and medical devices coated therewith and uses thereof for anti-thrombotic and/or ...
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WO/2022/158978A1 |
The invention relates to a kit of parts, consisting of compositions (C1) and (C2) in separate containers, for use in the treatment or prevention of osteoarthritis in a vertebrate, wherein: (a) composition (C1) is a liquid hydrogel formul...
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WO/2022/159923A1 |
Provided are biodegradable orthopedic implants, corrosion-resistant coating for orthopedic implants, and methods of making. The biodegradable orthopedic implant can include a Mg alloy having a coating including a first layer, a second la...
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WO/2022/157197A1 |
Described is an engineered heart tissue ( EHT) patch which is suitable for use in cardiac tissue implantation., particularly into a. human heart and/or onto a surface of a heart. The patch has. a three-dimensional tissue structure compri...
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WO/2022/159064A2 |
The present invention relates to a tissue filler which comprises two different phases, namely cross-linked and non-cross-linked; wherein tricarboxylic acid is included within non-cross-linked phase; which is made of hyaluronic acid gel a...
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WO/2022/156769A1 |
The present invention provides a tissue engineering scaffold. Specifically, the tissue engineering scaffold is a bio-gel-frame structure complex manufactured by uniformly filling a degradable bio-gel in a hard large aperture frame struct...
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WO/2022/157148A1 |
The invention relates to a process for preparing a drug carrier, to a correspondingly prepared drug carrier, a material kit and a use of a drug carrier of this type for the treatment of bone diseases. The process according to the inventi...
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WO/2022/159789A1 |
A non-immunogenic two-part clotting composition derived from human umbilical cords and methods of making thereof. The two-part clotting composition may comprise (a) a micronized human umbilical cord composition; and (b) an aqueous human ...
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WO/2022/158784A1 |
The present invention relates to a hydrogel comprising a decellularized tissue-derived extracellular matrix modified with a phenol derivative and to a composition for cell culturing, a composition for promoting cell differentiation, a ti...
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WO/2022/156648A1 |
An ear cartilage tissue engineering complex and a preparation method therefor. The complex comprises an ear cartilage gel or ear cartilage patch particles containing ear cartilage cells, and a porous frame structure. The ear cartilage ge...
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WO/2022/156645A1 |
The present invention provides a cartilage tissue engineering complex. Specifically, a graft comprises a cartilage gel or perichondral particles containing chondrocytes as well as a porous frame structure, and the cartilage gel or perich...
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WO/2022/156456A1 |
The present invention relates to the technical field of biological food materials, and disclosed in the present invention are a cross-linked hydrogel for muscle stem cell culture, and a preparation method therefor and an application ther...
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WO/2022/158816A1 |
The present invention relates to: a filler composition for reducing skin wrinkles, comprising stem cell-derived exosomes, hyaluronic acid, and BDDE; and a method for preparing same. The filler composition for reducing skin wrinkles accor...
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WO/2022/155147A1 |
Methods are provided for the ex vivo reprogramming of microbiopsies of tissue such as from the skin, wherein the cells from the tissue are reverted to a state capable of extensive expansion in volume and when transplanted in vivo, of pro...
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WO/2022/154645A1 |
The present invention relates to a biocompatible hydrogel comprising a component containing hyaluronic acid, polyethylene glycol and silicone and, more specifically, to a biocompatible hydrogel, a preparation method thereof, and the use ...
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