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WO/2023/009125A1 |
A delivery system for delivering at least one biological substance to a diseased or damaged area of a patient and having a sponge including a top sponge portion with a plurality of protrusions extending downwardly therefrom and a bottom ...
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WO/2023/006969A1 |
Porous hydrophilic composites for use in promoting bone growth are disclosed, along with methods for their preparation. The composites comprise a porous biodegradable polymer matrix, and nanosized calcium phosphate (CaP) homogeneously di...
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WO/2023/003321A1 |
Disclosed are an acellular thermal matrix manufacturing apparatus and an operation method therefor. The disclosed acellular thermal matrix manufacturing apparatus comprises: a plurality of treatment solution containers; a hopper configur...
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WO/2023/003265A1 |
Disclosed is a surface processing method for a dental implant, the method comprising the steps of: (a) performing laser processing of the surface of an implant; (b) etching the laser-processed surface of the implant; and (c) washing the ...
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WO/2023/003209A1 |
The present invention relates to a method for preparing a bone graft material that consists of a demineralized bone only and a bone graft material prepared thereby. According to the present invention, by a preparation method comprising: ...
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WO/2023/002372A1 |
The present invention consists of a method for the production of a shape-memory tissue through the use of polymeric matrices capable of temporarily modifying their shape, following the application of an external stimulus, and at the same...
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WO/2023/003384A1 |
The present invention relates to a powder formulation for tissue repair, a preparation method therefor, and an injectable composition for tissue repair, comprising same, and, more specifically, to: a powder formulation, a preparation met...
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WO/2023/002471A1 |
Biocomposite materials which overcome the drawbacks of the background art. Medical implants are provided that incorporate novel structures, alignments, orientations and forms comprised of such surface treated bioabsorbable materials, suc...
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WO/2023/000371A1 |
A bone repair scaffold, and a preparation method therefor and the use thereof. The bone repair scaffold is a three-dimensional porous scaffold, and the material of the bone repair scaffold comprises the following components in percentage...
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WO/2023/003025A1 |
The present disclosure includes a method for producing retinal tissue, the method comprising inducing differentiation of pluripotent stem cells to retinal tissue in a region A on a culture substrate, the culture substrate including on th...
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WO/2023/003212A1 |
The present invention relates to an artificial blood vessel provided with a piezoelectric vibration structure. The artificial blood vessel, according to the present invention, is provided with a piezoelectric vibration structure at one o...
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WO/2023/003430A1 |
The present invention relates to a method for increasing the thickness of an acellular dermal layer graft. Being capable of increasing the thickness of homologous dermis to a level similar to the skin thickness of a region to be grafted ...
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WO/2023/003808A1 |
The invention relates to dental bone grafting devices and magnesium meshes having features that are designed to corrode and/or absorb progressively, e.g., in stages, in order to improve dental bone regeneration, as well as methods for pr...
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WO/2023/001418A1 |
A method for manufacturing a photopolymerizable slurry comprises the steps of: providing a plurality of particles of an inorganic salt in the form of a powder; wherein at atmospheric pressure the inorganic salt has a melting point of abo...
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WO/2023/003431A1 |
The present invention relates to a method for producing an acellular dermal graft. The method according to one aspect minimizes DNA residue by effectively removing cells capable of causing immunorejection in a transplant patient, and thu...
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WO/2023/285859A1 |
This invention corresponds to a new alternative coverage for skin defects through the procurement of allografts of whole skin and the subsequent cryopreservation. The present invention seeks to provide a solution to the problem of tempor...
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WO/2023/285816A1 |
The present invention provides novel cell culture media and supplements for use in serum- free or reduced-serum cell culture. Corresponding methods and uses are also provided. The novel cell culture media and supplements are particularly...
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WO/2023/288218A1 |
Methods, devices and materials are for in situ formation of an implant for treating a nerve. A treatment site is positioned within a cavity defined by a form. The form may facilitate placement of a nerve stimulating device adjacent to th...
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WO/2023/285813A1 |
The present invention provides novel cell culture media and supplements for use in serum- free or reduced-serum cell culture. Corresponding methods and uses are also provided. The novel cell culture media and supplements are particularly...
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WO/2023/284107A1 |
A hydrogel microsphere for adsorbing a growth factor in a stem cell supernatant, and preparation thereof, relating to the technical field of biomedicine. Hydrogel microspheres having different diameters and different proportions can be p...
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WO/2023/288321A1 |
Disclosed are hydrogel systems with tunable stress-relaxation properties prepared from a polypeptide with one or more primary cross-linkable groups and a polysaccharide with one or more secondary cross-linkable groups. The resulting hydr...
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WO/2023/287106A1 |
The present invention relates to a method for preparation of a filter containing a DNA fraction and a filler prepared thereby. Despite low contents of the components in the filler, the preparation method of the present invention can secu...
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WO/2023/287727A1 |
In some embodiments, the present disclosure pertains to liquid compositions for medical use that comprise (a) a polymer, a monomer, a macromonomer, or a combination of any two or all three of the foregoing and (b) spherical metallic part...
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WO/2023/283440A1 |
A device for permanent placement across an atrial appendage ostium in a patient includes a support structure having a contracted delivery configuration and an expanded deployed configuration defining a radially enlarged portion to perman...
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WO/2023/283481A1 |
A novel method of making a 3D-shaped 3D graphene (3D2G) is disclosed. The method involves a) 3D printing a catalyst slurry via Direct Ink Writing (DIW); b) depositing the printed slurry using chemical vapor deposition (CVD) to produce a ...
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WO/2023/282247A1 |
To address the problem of providing a tissue formation agent, the present invention provides a tissue formation agent containing alginic acid or a salt thereof.
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WO/2023/279807A1 |
Disclosed are a braided tube forming device used for assisting in manufacturing of braided tubes, and a use method. In at least one embodiment, the device provides at least one elongated mandrel, and at least one elongated radially contr...
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WO/2023/283141A1 |
An alginate-based nutritional product ("AP") comprising a composition and digestive aid. AP includes alginate as a demulcent (protective), raft-forming, stabilizing agent, polylysine, dextrose and grapefruit seed extract preservatives. T...
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WO/2023/282658A1 |
The present application relates to a composition for preparing a temperature-sensitive hydrogel and to a use thereof, and provides a temperature-sensitive hydrogel composition and a method for preparing a temperature-sensitive hydrogel c...
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WO/2023/279851A1 |
Disclosed in the present invention are a dry-state biological tissue material and a preparation method therefor. The preparation method comprises: subjecting a biological tissue material to a decellularization treatment by using decellul...
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WO/2023/279943A1 |
Disclosed in the present application is a method for treating a biological tissue material. The method is characterized by comprising the following steps: first fixing, involving: placing a biological tissue material in a glutaraldehyde ...
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WO/2023/279665A1 |
The present application provides an antibacterial lubricant coating. The antibacterial lubricant coating comprises a ferroelectric material base layer and a lubricating layer that is provided on the surface of a side of the ferroelectric...
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WO/2023/281124A1 |
Accelerated development of functional three-dimensional tissue moduli.The present invention relates to a process for the production of two and three-dimensional tissues and to tissues produced by the method. The present invention further...
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WO/2023/283304A1 |
A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes ap...
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WO/2023/280452A1 |
The invention relates to a method for producing an augmenting active agent which has a composite material for reconstructing or regenerating an at least partly lost bone substance, for filling up bone defects, and/or for optimizing a bon...
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WO/2023/282337A1 |
The purpose of the present invention is to provide a therapeutic composition, in particular, a transplant therapy composition, which allows for cryopreservation without damage to cells due to thawing, and which can be administered to a p...
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WO/2023/282338A1 |
The purpose of the present invention is to provide a cell seeding agent and a substrate for transplantation use which enable a subculture operation without causing the transformation of cells and also enable the efficient engraftment of ...
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WO/2023/282554A1 |
The present invention relates to a method for increasing the yield or amount of collagen through pH titration and, more specifically, to a method for increasing the yield or amount of collagen through stepwise pH titration. In a collagen...
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WO/2023/281054A1 |
A method of producing an alloy comprising magnesium and calcium, preferably an implantable medical device comprising magnesium and calcium, comprises the steps of generating a billet comprising magnesium and calcium, and extruding the bi...
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WO/2023/283640A1 |
Electroadhesion, adhesion induced by an electric field, occurs between non-sticky cationic and anionic hydrogels. When gel and tissue are placed under an electric field, the pair strongly adhere, and the adhesion persists indefinitely th...
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WO/2023/278875A1 |
Provided herein are biomimetic osteochondral implants (100) that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which th...
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WO/2023/275241A1 |
The present invention refers to hyaluronic acid crosslinked with polyglycerol polyglycidyl ether containing local anesthetic agents, to a process for its preparation and its use in therapy, cosmetics and as a carrier.
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WO/2022/247930A9 |
Compositions and methods involving microspheres composed of mesenchymal cells such as dermal papilla cells (DPCs) and extracellular matrix, epithelial cell such as keratinocyte are disclosed. It has been discovered that by balancing the ...
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WO/2023/277235A1 |
The present invention relates to a human body plastic implant having an integrated radial silicone cell structure, and a manufacturing method therefor and, more specifically, to a human body plastic implant having an integrated radial si...
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WO/2023/278290A1 |
A prosthesis for reconstruction and/or augmentation of an anatomical shape. The prosthesis may have a three-dimensional configuration to reconstruct and/or augment the anatomical shape of a human breast. The prosthesis may be configured ...
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WO/2023/277426A1 |
An implant fixture for reducing periodontitis is disclosed. The implant fixture for reducing periodontitis according to an embodiment of the present application may comprise a body part which is implanted in bone tissue and forms an arti...
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WO/2023/275821A1 |
The invention relates to a method for decellularizing a tissue and/or organ that comprises immersing an isolated tissue and/or organ in an enzyme solution and a step of irradiating the tissue with ionizing electromagnetic radiation. The ...
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WO/2023/272355A1 |
The present invention relates to methods for providing a mineral or mineral-composite film, the method comprises the steps of: providing a layer comprising a calcium-based mineral, wherein the layer is produced using convective self-asse...
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WO/2023/275278A1 |
The present invention relates to a dermal filler composition based on crosslinked hyaluronic acid, wherein the hyaluronic acid is crosslinked with a high molecular weight polyethylene glycol diglycidyl ether (PEGDE) crosslinker having an...
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WO/2023/278654A1 |
An arthroscopic system for the repair of a ruptured anterior cruciate is provided. Aspects of the invention include a scaffold attached by a suture to an fixation device and inserted into a repair site via arthroscopic equipment. The sca...
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