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WO/2018/039130A1 |
A variable spacing PCR amp tube rack can include a plurality of rotors and a plurality of carriages engaged with the rotors so that rotation of the rotors causes translation of the carriages with respect to one another. The rack can incl...
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WO/2018/036895A1 |
The present invention relates to a compact thermal cycling device (1) for heating and cooling at least one housing mount (2) for housing a lower portion of a reagent tube (3), adapted for conducting heat into or out of same; and a thermo...
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WO/2018/034540A1 |
The present invention relates to: an inlet/outlet structure of a microfluidic chip optimized to seal an inlet/outlet thereof by using a UV-curable sealing material; a microfluidic chip having the inlet/outlet structure; and a method for ...
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WO/2018/031155A1 |
System and methods that provide reliable heating/cooling and mixing, coupled with uniform delivery of reagents at microscale sizes, are described herein. A microreactor vessel having one or more ports is used in a microscale reaction. So...
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WO/2018/029252A1 |
The present invention relates to a measurement apparatus (5) for determining chemical and/or physical properties of a substance. Here, the measurement apparatus comprises a light-source device (108) for emitting light, wherein the light-...
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WO/2018/025053A1 |
A system for the remote live auditing of biological samples contained in a cold storage vessel (10). The vessel (10) comprises one or more canisters (100(1), 100(2)), each of which comprises a connector (102(1), 102(2)) and is configured...
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WO/2018/017769A1 |
An environmental control system for use in a clinical analyzer module includes an upper deck environmental subsystem comprising a far field sensor, one or more heaters, one or more spine cooling fans, and one or more in-line fluid heat e...
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WO/2018/017768A1 |
Systems and methods for refrigerated storage of controls and calibrators utilize a refrigerant storage assembly having an insulated housing and door assembly, thermoelectric coolers, and the refrigerated base assembly having a metal plat...
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WO/2018/017759A1 |
One embodiment provides a method of controlling a payload temperature in in vitro diagnostics including: moving, using a track system, a plurality of carriers, along one or more paths between a plurality of testing stations, wherein the ...
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WO/2018/005870A1 |
Disclosed herein are methods and devices for preparing a sample of nucleic acid molecules from a biological sample. The methods and devices may perform similarly to or better than standard sample preparation methods. The nucleic acid mol...
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WO/2018/004301A1 |
The present invention relates to an apparatus for performing a nucleic acid amplification reaction and a fluorescence detection device for reaction analysis. The nucleic acid amplification apparatus of the present invention uses a plural...
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WO/2018/005843A1 |
Designs of a digital microfluidic devices are described comprising droplet control electrodes and heating electrodes that have effects in the regions for droplet manipulations. Specifically, the digital microfluidic device comprises a fi...
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WO/2018/002649A1 |
Disclosed is a method of performing a non-isothermal nucleic acid amplification reaction, the method comprising the steps of: (a) mixing a target sequence with one or more complementary single stranded primers in conditions which permit ...
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WO/2017/223026A1 |
Apparatuses and methods for detecting a target RNA sequence or sequences using a ligation assisted loop mediated isothermal amplification (LA LAMP) assay. In particular, described herein are methods for LA LAMP including digital micro fl...
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WO/2017/213587A1 |
An apparatus for thermally processing reaction material containing nucleic acid, e.g. by PCR, is provided. The apparatus comprises a reactor holder (4) statically holding a plurality of reactors (5); at least two heating means (heating b...
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WO/2017/213586A1 |
Apparatus for thermal processing of nucleic acid in a thermal profile is provided. The apparatus employs a reactor holder for holding reactors to accommodate reaction material containing nucleic acid. The apparatus comprises: at least tw...
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WO/2017/213592A1 |
Apparatus and method for thermal processing of nucleic acid in a thermal profile is provided. The apparatus employs a reactor holder for holding reactor(s) each accommodating reaction material containing the nucleic acid. The apparatus c...
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WO/2017/213590A1 |
An apparatus for thermal cycling nucleic acid is provided, the apparatus employing a reactor holder for holding reactor(s) (15) to accommodate a reaction material containing nucleic acid. The apparatus comprises a transfer means (85) for...
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WO/2017/213589A1 |
Method and apparatus for thermal processing of nucleic acid in a thermal profile is provided. The method employs at least a first bath and a second bath, the method further employing a reactor holder for holding reactor(s) accommodating ...
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WO/2017/213591A1 |
Apparatus for thermal processing nucleic acid in a thermal profile is provided. The apparatus employs a reactor holder for holding reactor(s) each accommodating reaction material containing the nucleic acid. The apparatus comprises a fir...
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WO/2017/204512A1 |
A PCR Module is detachably coupled to a Reader System. The PCR module includes a base substrate, an optical sensor assembly, a partition wall, a cover, sample-carrying elements, a hydrophobic film, and a control circuit. The optical sens...
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WO/2017/203278A1 |
There is provided a cryogenic cooling system for providing optical communication with a sample holder. The cryogenic cooling system comprises a cooling device and a sample holder, wherein the sample holder is removably mountable to the c...
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WO/2017/204513A1 |
A PCR module is coupled to a reader system in an attachable/detachable manner, and comprises a base substrate, an optical sensor assembly, a barrier, a cover, a flat valve, a sample injection portion, and a buffer material injection port...
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WO/2017/202648A1 |
A fluid flow module for biochemically processing a liquid, which module can be rotated with a controllable angular velocity about an axis of rotation, wherein a first fluid chamber is arranged essentially in a circular first temperature ...
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WO/2017/193989A1 |
A liquid heater (6) for use in an analyzer, comprising a heating element (602) and at least a first liquid receiving chamber (604) and a second liquid receiving chamber (606) which are not communicated with each other in the heater (6), ...
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WO/2017/185067A1 |
An apparatus includes a substrate, a first heating element, and a second heating element. The substrate includes a first portion, a second portion, and a third portion that is between the first portion and the second portion. The first p...
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WO/2017/181100A1 |
System, heaters, and heat transfer devices are disclosed. For example, a system for performing polymerase chain reaction includes a support member configured to receive a sample vessel and a heater that is positioned to affect a temperat...
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WO/2017/181069A1 |
The present invention relates to a microfluidic system including a temperature controller and a thermoplastic microfluidic chip that enables rapid PCR in a PCR chamber of the microfluidic chip. Thermal control of the PCR chamber is achie...
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WO/2017/172760A1 |
The present disclosure provides methods, composition and devices for performing convection-based PCR and non-enzymatic amplification of nucleic acid sequences. Techniques and reagents employed in these methods include toehold probes, str...
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WO/2017/160836A1 |
Systems and methods for performing biological assays are provided herein. The systems and methods determine one or more characteristics of a nucleic acid amplification sample based on a modified optical property of the sample.
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WO/2017/156126A1 |
A PCR amplification and product detection system is disclosed. The system utilizes a uniform and direct photonic heating subsystem to mediate reaction-by-reaction, high-throughput PCR amplification detectable by a fluorescence detection ...
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WO/2017/153761A1 |
A sample heating/cooling device (2) comprises a plurality of members (6) operable in use to heat and/or cool one or more samples (22), Each member (6) has a sample contact surface and is biased towards a resting position under the operat...
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WO/2017/151098A1 |
A liquid directing sample container includes a well. The well has sides and a floor. The sides having a non-circular profile having an interior angle that, at a target location within the well, is smaller than other interior angles of th...
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WO/2017/147085A1 |
Instruments, methods, and kits are disclosed for performing fast thermocycling.
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WO/2017/139447A1 |
The present disclosure provides methods and systems for analyzing nucleic acids and for conducting chemical and/or biological reactions.
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WO/2017/131740A1 |
A sample-reagent mixture is thermal cycled through a plurality of cycles. Each thermal cycle includes actuating a heater to heat the sample-reagent mixtures; and dispensing a fluid onto the sample-reagent mixture to cool the sample reage...
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WO/2017/126761A1 |
An in-vitro diagnostic apparatus having a cartridge according to the present invention comprises: a body to/from which a bio-chip can be attached/detached and which has a plurality of sample accommodating chambers; and a cartridge which ...
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WO/2017/127570A1 |
Devices are disclosed for amplifying and detecting analytes, including oligonucleotide targets. The devices may be used for point of care nucleic acid testing. Methods and assays of using the devices are also disclosed.
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WO/2017/119639A1 |
The present invention relates to a surface measurement sensing-based real time nucleic acid amplification measuring device characterized by comprising: a microfluidic chip having a microfluidic channel formed in a closed loop shape; a sa...
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WO/2017/119902A1 |
Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, a fluid output, and a set of microfluidic channels that fluidly connect the fluid input and the fluid output. Each microfluidic channel...
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WO/2017/119904A1 |
Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, ejection nozzles, and a set of microfluidic channels that fluidly connect the fluid input and the ejection nozzles. Each microfluidic c...
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WO/2017/116037A1 |
A multiple molecular diagnosis chip structure according to one embodiment of the present invention comprises: a reaction pad having a sample passage hole formed therethrough and a plurality of reaction patterns formed thereon, wherein an...
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WO/2017/112836A1 |
A thermal cycler system for use with a sample holder configured to receive a plurality of samples includes a sample block configured to receive the sample holder, a cover lid configured to move in a direction toward the sample block from...
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WO/2017/112833A1 |
A thermal cycler system for use with a sample holder (20) configured to receive a plurality of samples includes a sample block (14) having an upstanding peripheral side wall and being configured to receive the sample holder (20) and an a...
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WO/2017/109246A1 |
The invention relates to a device (1) for maintaining constant the temperature of a sample-holder (2), which device has: a thermal recipient (3) containing a cryogenic liquid (4); a vessel (5) through which the cryogenic liquid (4) flows...
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WO/2017/106542A1 |
A solid fluorescence standard that can be used to calibrate and/or normalize a device (e.g., a scientific instrument) that is configured for generating and collecting fluorescence data. A fluorescence standard disclosed herein includes a...
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WO/2017/097289A1 |
The invention relates to a temperature-control device having a reaction vessel (1), comprising a heat-insulated interior (2) covered by a cover (3), in which interior the reaction vessel (1) is accommodated. The reaction vessel (1) consi...
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WO/2017/100223A1 |
A reinforced microplate has reinforcing members that enhance stiffness and minimize deformation of the microplate, especially thermally-induced deformation. The reinforcing members include dots, ribs or struts that are integrally formed ...
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WO/2017/096110A1 |
A method and device for optimizing the process of identification of pathogens is disclosed. The method includes obtaining nucleic acids specific to the pathogen, wherein obtaining nucleic acids specific to the pathogen includes amplifyin...
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WO/2017/093763A2 |
A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable ...
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