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WO/2006/065766A2 |
A mixing device for mixing a light hydrocarbon feed, a steam feed, and an oxygen-containing gas stream to form a feed mixture is disclosed. The autoignition of the feed mixture is prevented prior to conversion of the feed mixture to synt...
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WO/2006/035800A1 |
A thin film heater (2) is provided with a thin film heat element, and first and second thin film electrodes (22, 24) which are electrically connected to the thin film heat element for applying a voltage to the thin film heat element. In ...
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WO/2006/027757A2 |
The present invention concerns a microfluidic device (1) for performing physical, chemical or biological treatment to at least one packet without contamination.
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WO/2006/024392A2 |
The invention relates to a receiving unit for biological objects, which comprises a plate-shaped element (1) provided with a plurality of openings (2). Said openings are arranged, in particular, in a manner such that they correspond to t...
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WO/2006/024879A1 |
A reaction vessel for use in thermal cycling reactions is disclosed. The vessel (10) has a width greater than its depth, to give the vessel a flattened profile. The side walls (22) of the vessel extending across the width of the vessel a...
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WO/2006/013303A1 |
The invention concerns a device for moving a small volume of liquid under the effect of an electric control, comprising a first substrate with hydrophobic surface (29) provided with electrically conductive means (24), second electrically...
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WO/2006/007884A1 |
The invention relates to a cooling device (1) for cooling an item to be cooled, especially for use in the examination, handling and processing of cryogenic samples. Said device comprises a cooling compartment (3) for receiving the item t...
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WO/2006/002226A1 |
Systems and methods for thermal cycling samples that include pneumatic automation are provided by the present teachings.
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WO/2006/002403A1 |
The present application relates to an apparatus and method for thermal cycling using a source of cooling gas. The apparatus comprises a plurality of retaining elements (30) adapted to receive the wells and a source of cooling gas (50). E...
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WO/2005/118774A1 |
A method and a device for controlling temperature capable of accurately controlling the temperature of microorganism. The device comprises a plurality of cells (2) storing the microorganism, heaters (11), (12), ..., (1n), and a cooling p...
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WO/2005/118867A2 |
Methods and apparatus for genome analysis are provided. A microfabricated structure including a microfluidic distribution channel is configured to distribute microreactor elements having copies of a sequencing template into a plurality o...
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WO/2005/118773A2 |
The present invention provides miniaturized instruments (101) for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for perform...
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WO/2005/118144A1 |
The invention relates to a method for rapid thermal control of a reaction volume (4) of a reaction vessel (2) for a change of temperature of the reaction volume (4) from a preceding temperature to a target temperature. Characteristic for...
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WO/2005/119391A1 |
The invention relates to a valve device (1), often also referred to as distribution valve, for adjusting a medium flow (L1, L2) of a PCR device. An inlet channel (7) leads to a valve chamber (3) of a valve housing (2), while two outlet c...
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WO/2005/115621A1 |
A method for coding and identification of biological samples for in vitro fertilisation comprises the steps of applying to receptacles intended for unfertilised eggs and sperm, respectively, an identification code characteristic of the p...
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WO/2005/116202A1 |
A reaction vessel, a reaction measuring device, and a liquid rotating treatment device accurately enabling the temperature control of a liquid stored in the vessel with faithful responsiveness. The reaction vessel comprises a storage cha...
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WO/2005/115624A1 |
The invention relates to tempering methods for performing a defined, particularly a cyclical thermal treatment of small amounts of liquid on substrates. According to the invention, one or several amounts of liquid are applied to a substr...
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WO/2005/113148A1 |
Methods and systems for performing single molecule amplification for detection, quantification and statistical analysis of nucleic acids are provided. Methods and systems are provided for determining and quantifying lengths of nucleic ac...
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WO/2005/113825A1 |
An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
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WO/2005/108620A2 |
Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain polynucleotides under a first set of conditions (...
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WO/2005/108604A2 |
The invention relates to devices and methods for detecting specific interactions between probe and target molecules. The invention especially relates to a device for the qualitative and/or quantitative detection of molecular interactions...
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WO/2005/107938A2 |
An M x N matrix microfluidic device for performing a matrix of reactions, the device (100) having a plurality of reaction cells (106) in communication with one of either a sample inlet (120) or a reagent t inlet (124) through a via forme...
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WO/2005/106040A2 |
A method for preparing a sample suspected to contain a target nucleic acid sequence for a nucleic acid amplification reaction and for verifying the effectiveness of the sample preparation comprises the step of mixing the sample with samp...
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WO/2005/106031A1 |
A method of hybridization in which efficient hybridization reaction can be carried out. Further, there are provided, using this hybridization method, a method of detecting a target gene with high sensitivity and a method of signal amplif...
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WO/2005/106024A1 |
The invention relates to a DNA isolation method by removal of constituents, interfering with a subsequent PCR. According to said method, all substances and method steps are fully integrated into a closed unit (cartridge) for single use, ...
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WO/2005/106449A1 |
An apparatus for use in controlling the temperature of one or more substances passing through one or more microfluidics channels in an analysis device is set forth. The apparatus comprises a heating unit having first and second surfaces....
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WO/2005/103295A2 |
A method and tools for the analysis of nucleic acids has been disclosed, in particular the present invention relates to the isolation of genomic DNA from cells and its enzymatic modification. The subjects of the present invention are use...
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WO/2005/103589A2 |
An insulated container for maintaining low temperatures during irradiation of vessels of biological materials is designed to hold the vessels of biological materials and dry ice or other cooling element used to achieve and maintain low t...
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WO/2005/100538A1 |
A system is provided for carrying out rapid nucleic acid amplification or other biological reactions requiring thermal cycling. The system of this invention incorporates at least two heating blocks, each having a groove for receiving a r...
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WO/2005/101462A2 |
A low permeable hose that has an increased resistance to permeation of refrigerants. The hose includes refrigerant barrier layer (14) that is positioned between an innermost layer (12) and an outer layer (22). The refrigerant barrier lay...
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WO/2005/101464A2 |
A metallic glass-coated microwire (1) has controllable surface porosity. The porosity is achieved by etching the metallic glass-coated microwire or other shapes of glass-coated bodies with acid after annealing to produce a multi-phase gl...
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WO/2005/097325A1 |
The present invention relates to a device for temperature controlled sample analysis comprising a frame provided therein with a sample holder unit made of a thermally conducting material suitable for housing a plurality of samples, a tem...
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WO/2005/094981A1 |
A cyclic reactor system for amplifying nucleic acids using the polymerase chain reaction (PCR) process is provided, wherein the reaction chamber (l) is partitioned in reaction chamber portions (2a,2b,2c). The entity of all reactor chambe...
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WO/2005/093038A1 |
The invention relates to an autonomous incubator for biological material for creating and maintaining a predefined CO2 environment inside at least one inner chamber of the incubator comprising a regulating device for regulating the CO2 c...
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WO/2005/093485A1 |
A specimen temperature controller, comprising a specimen table (100) on which a culture container (150) containing an observed specimen (162) is placed and a temperature control element (103) mounted on the specimen table (100). The spec...
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WO2005028110B1 |
A reaction plate (22) comprises a plurality of reaction cells (34), wherein the plate (22) comprises a thermal conductive material, each of the wells (34) has an open top and a closed bottom, and a distance between the wells is less than...
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WO/2005/082535A1 |
A microfluidic system (40) achieves fluid flow control and manipulation without moving parts. It has a channel in a circuit in a vertical plane having a gravity-opposed leg (41) and a gravity-assisted side having five branches (42-46). A...
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WO/2005/080606A1 |
The present invention describes microfluidic devices that provide novel fluidic structures to facilitate the separation of fluids into isolated, pico-liter sized compartments for performing multiplexing chemical and biological reactions....
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WO2005028109B1 |
An inverted microplate (22') having a plurality of reaction wells (34') and a transparent cover (24). The plate (22') comprising a solution (38) in a well (34'), a surface of the cover (24) in contact with the solution (38) and the head ...
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WO2005054431A9 |
The present invention relates to methods and apparatus for conducting densely packed, independent chemical reactions in parallel in a substantially two-dimensional array. Accordingly, this invention also focuses on the use of this array ...
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WO2005030925A9 |
A microfluidic device comprises a matrix of rotary flow reactors. The microfluidic matrix device offers a solution to the "world-to-chip" interface problem by accomplishing two important goals simultaneously: an economy of scale in reage...
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WO/2005/075683A1 |
A high-throughput device is structured to perform a continuous-flow reaction, e.g., a polymerase chain reaction (PCR) requiring repetitive temperature control in a timely fashion.
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WO/2005/073734A1 |
The present application relates to an apparatus and method for heat transfer for thermal cycling. According to various embodiments, a device for thermally cycling a sample comprises at least one heating element; a disc configured to rece...
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WO/2005/073410A2 |
Embodiments of the present invention are directed to methods and devices/systems for amplifying genetic material and may include providing a water-in-oil emulsion in a continuous flow. The emulsion may include a plurality of water drople...
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WO/2005/070546A1 |
A device (420) and method for real-time amplification and detection of a large number of target nucleic acids contained in a large number of biological samples is provided. The device (420) can comprise a substrate (422) and an optically...
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WO/2005/070545A1 |
The invention relates to a contamination barrier (5) enabling efficient and reproducible processing of a high number of samples, avoiding contamination from aqueous solutions (3) in open and/or automated systems, especially within the pp...
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WO/2005/069964A2 |
Described are an apparatus (4) and method of moving micro-droplets. A surface (8) has a liquid phase (12) thereon. In the liquid phase is a droplet (14). Focused at an edge of the droplet is a beam of light (28). The light beam produces ...
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WO/2005/068607A1 |
A temperature control device capable of accurately controlling the temperature of microorganisms or cells when the device is used, for example, for the culture of the microorganisms or cells, comprising a plurality of cells (2) storing t...
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WO/2005/068066A1 |
A temperature controller that by creating of a temperature gradient on a heat conductor surface, can simultaneously adjust multiple samples disposed on the surface to different temperatures and can regulate a temperature profile of the h...
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WO/2005/066372A2 |
Devices, assemblies, systems and methods described herein enable detection of as few as a single copy of a target nucleic acid molecule. Polynucleotides copied from a single or a small number of target nucleotide(s) within regions near t...
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