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WO/2010/112273A1 |
The invention relates to a device for accommodating a biosensor, comprising a means for the electrical, fluidic, and thermal coupling of the biosensor, comprising a flap mechanism (26). In a closed state, the flap mechanism causes the bi...
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WO/2010/092137A2 |
The invention comprises a method for testing the accuracy and reliability of a thermal unit of a thermal cycler or an enclosure of a PCR thermal cycler thermally controlled by pulsed air, said thermal unit and enclosure thermally control...
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WO/2010/089470A1 |
The invention relates to a thermal validation apparatus (302) including at least one lining (316), each lining defining a sink (314) and intended to be inserted into a respective recess of the thermal processing device for heating or coo...
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WO/2010/088496A1 |
A signal detection system configured for detecting a signal emitted by the contents of a reaction receptacle is also configured to apply thermal energy to a portion of the reaction receptacle to affect a reaction occurring within the rea...
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WO/2010/084149A1 |
The invention relates to a plastic container or conduit for a cooling system, a heating system, an air intake system, an exhaust system, a pressure system or a fuel system, consisting of, or comprising a part or a layer made of a thermop...
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WO/2010/072790A1 |
The method for detecting the presence of liquids includes detecting an initial temperature (Tl) in a channel (9) accommodating a liquid; heating the channel for a predetermined test time (Δt2); detecting a test temperature (T2); determi...
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WO/2010/064160A1 |
To provide a thermal cycling system allowing an efficient thermal cycling and an optical detection during the diagnostic process a thermal cycling system is proposed, comprising: at least one heating device (10a, 10b) having a transparen...
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WO/2010/057858A1 |
The present invention relates to a device for automatically analyzing liquids, comprising a carousel for liquid containers, wherein the carousel comprises a reagent and/or sample carousel that rotates about a central axis of rotation, wh...
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WO/2010/051252A1 |
A thermally controlled device includes a flow-through expandable pouch with a fluid inlet, a fluid outlet, a first side surface, and a second side surface. A first thermoelectric cooler (TEC) is coupled to the first side surface and a se...
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WO/2010/041088A1 |
An integrated gel based microfluidic sample processing device An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime,comprising a substrate having a plurality of micro-...
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WO/2010/041214A1 |
The present invention provides an integrated micro fluidic device (100) comprising a plurality of fluidic chambers (20) provided on a substrate (19), the plurality of fluidic chambers (20) being logically organized in rows and columns, e...
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WO/2010/035063A1 |
The present invention is related to a thermocycling device (10), comprising at least one sample holder (11), at least one thermal reference (12) and at least one heating and/or cooling device (13), which is arranged between said sample h...
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WO/2010/033604A2 |
Provided herein is a portable thermocycler, comprising: (i) a case; (ii) a rotary plate in the case; (iii) a plurality of heating blocks arranged in a geometric pattern disposed on the rotary plate; and (iv) at least one vessel adapted t...
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WO/2010/030647A1 |
A carrier tape (20) wound on and extending between first and second spools (40) rotatably mounted to a read head (12) is submerged with a detector (44) mounted on a guide mechanism (42) into a fluid thermal media in the form of water or ...
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WO/2010/022417A1 |
The present invention relates to a device for thermally regulating a rotationally symmetrical container having a lateral surface and/or a base surface, said device comprising at least one thermal-regulation block which is suitable for ac...
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WO/2010/012494A1 |
The invention relates to a heating/cooling device for carrying out a heating/cooling programme for at least one sample, in particular a PCR sample, comprising: at least one heating/cooling block which is constructed for receiving the at ...
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WO/2010/010361A1 |
Apparatus for effecting a chemical or biological reaction comprising: a heat removal module comprising a thermally conductive material having therein a channel adapted for the flow of a coolant liquid, a heating element mounted upon the ...
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WO/2010/004246A1 |
A sample carrier, such as a test chip (10), is provided with at least a pair of electrodes (38, 40) at the extremities of a sample holding zone (16, 18, 32-36). A power source (52) is operable to supply electrical potential to the electr...
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WO/2009/141390A1 |
The present invention pertains to a device and method to measure thermo-optical, preferably thermophσretic, characteristics of particles in a solution. The method comprises the steps of: (a) providing a sample probe comprising marked pa...
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WO/2009/135943A2 |
The invention relates to a housing for a sample in the form of at least one chemical and/or biological substance, wherein the housing has at least one Peltier element (4) for temperature control of the sample (5), integrated in a wall (3...
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WO/2009/122191A1 |
A system (20) for a PCR reaction includes an array of reaction vessels mounted on a thermal mount (21). The thermal mount (21) is provided with a liquid path therein coupled to a cooling liquid input port (22), a heating liquid input por...
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WO/2009/115335A1 |
The invention relates to a method for the thermal control of at least one temperature-dependent enzymatic reaction in the presence of magnetic particles, particularly nanoparticles, or magnetic beads, in vitro by heating the magnetic bea...
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WO/2009/111316A2 |
The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, pu...
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WO/2009/107065A1 |
A reactor system (100) for carrying out a reaction, comprising at least one reaction chamber (110) for holding reactants of the reaction; a thermal element (120) for heating or cooling the reactants of the reaction chamber (110); and an ...
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WO/2009/100933A1 |
A device for the heating of covers of reaction vessels, which comprises the following components: (a) a directly and/or indirectly heated plate (1), having an upper side (1a), which is at least designed with one or without recessed porti...
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WO/2009/102924A1 |
A thermal cycling instrument for PCR and other reactions performed on multiple samples with temperature changes between sequential stages in the reaction procedure is supplied with a thermal block to provide rapid changes and close contr...
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WO/2009/101211A1 |
The invention relates to a mobile device system, comprising a hand-held device and a test kit for the mobile isolation of nucleic acids. The hand-held device comprises at least one sample block for inserting sample containers, a sample b...
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WO/2009/092564A2 |
The present invention is directed to an integrated system for oligonucleotide synthesis and PCR. The integrated instrument of the inventive system is basically composed of two independent modules which are operatively linked to each othe...
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WO/2009/094061A1 |
A system (100) for thermal cycling a material (115) to be thermal cycled including a microfluidic heat exchanger (101); a porous medium (113) in the microfluidic heat exchanger (101); a microfluidic thermal cycling chamber (103) containi...
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WO/2009/083648A2 |
The invention relates to a polymerase chain reaction (PCR) process and a thermal cycler. In the process, biological samples are held in a sample carrier (10) having a plurality of sample spaces (12) each having upper and lower ends and t...
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WO/2009/067744A1 |
Apparatus for controlling the temperature of a reaction mixture held within a reaction container, the apparatus including a radiation source for exposing the reaction container to radiation thereby heating the reaction mixture, a tempera...
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WO/2009/059430A1 |
A microfluidic device comprising a plurality of reaction chambers in fluid communication with a flow channel formed in an elastomeric substrate, a vapor barrier for preventing evaporation from the plurality of reaction chambers, and a co...
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WO/2009/057014A2 |
The invention relates to the detection of infectious diseases. A system for automatic detection of infectious diseases is disclosed. The system comprises an input unit for receiving a blood sample, a lysis unit, a PCR unit, a sample unit...
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WO/2009/046348A1 |
A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder conta...
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WO/2009/039097A1 |
A thermalcycler includes a first thermalcycler body section having a first face and a second thermalcycler body section having a second face. A cavity is formed by the first face and the second face. A thermalcycling unit is positioned i...
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WO/2009/030908A2 |
An apparatus (40) for a PCR reaction includes an array (41) of reaction vessels (42) is mounted on a thermal mount (43). The thermal mount (43) is positioned on a on a heater/cooler (45), such as a Peltier module. The array (41 ) is cove...
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WO/2009/022150A1 |
Biochemical assay apparatus uses a container with a sleeve of electrically- conductive material (300) to heat it. The heating is done inside a chamber and a contactless heat sensor (110) such as a thermopile or a bolometer, also inside t...
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WO/2009/019452A1 |
A reaction vessel for carrying out a chemical or biochemical reaction, such as a polymerase chain reaction, said vessel having a coating of parylene or a derivative thereof, on at least the surface which contacts reactants.
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WO/2009/019454A1 |
A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein at least one wall of said vessel comprises a metallic layer and an inner non-metallic layer. Reaction systems comprising com...
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WO/2009/019450A1 |
A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein electrically conducting polymer is arranged to act as a heating element. The profile of the electrically conductive polymer ...
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WO/2009/019658A2 |
An integrated microfluidic device having a chamber (11-MN) for heating a fluid, multiple heating elements for heating different parts of the chamber, multiple temperature sensing elements (Rs, D1) for localized sensing of temperature of ...
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WO/2009/011942A2 |
A fast, multiplexed PCR system is described that can rapidly generate amplified nucleic acid products, for example, a full STR profile, from a target nucleic acid. Such systems include, for example, microfluidic biochips and a custom bui...
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WO/2009/002144A1 |
The present invention provides a system, comprising at least one reactor array, comprising at least two reactor vessels (2) a connecting member for fixating the at least two reactor vessels relative to each other (4, 5) at least one reac...
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WO/2008/149282A2 |
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WO/2008/127791A1 |
An automated real-time flow-through system capable of processing multiple samples in an asynchronous, simultaneous, and parallel fashion for nucleic acid extraction and purification, followed by assay assembly, genetic amplification, mul...
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WO/2008/124116A1 |
A fast, multiplexed PCR system is described that can rapidly generate amplified nucleic acid products, for example, a full STR profile, from a target nucleic acid. Such systems include, for example, microfluidic biochips and a custom bui...
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WO/2008/117213A2 |
An assembly of at least two printed circuit boards includes an intermediate connection layer (40) for providing electrical and mechanical connections between first and second circuit boards (10,12). The intermediate connection layer comp...
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WO/2008/117210A1 |
An integrated micro fluidic device having a chamber (11-MN) for heating a fluid, multiple heating elements for heating different parts of the chamber, multiple temperature sensing elements (Rs, D1) for localized sensing of temperature of...
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WO/2008/117209A1 |
An integrated microfluidic device has a plurality of chambers (11-MN) on a substrate for handling fluids, a chamber circuit (R, Rs, D1, T1, T2, T3, T4) integrated on the substrate for switching signals related to that chamber, and an int...
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WO/2008/117200A2 |
An integrated micro fluidic device having a number of chambers (11-MN) for heating a fluid, a number of electrical heating elements (R) for heating different ones of the chambers, a controller for controlling the heating elements to vary...
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