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WO/2017/085472A1 |
The present invention discloses an apparatus for conducting an assay, wherein the apparatus comprises a turntable (1) for receiving an assay disc (100) and to control an assay on said assay disc by rotational movement of said turntable, ...
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WO/2017/079636A1 |
Methods, kits and mixtures are provided for performing RT-PCR with an RT incubation of no more than one minute and PCR cycles in <20 seconds per cycle.
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WO/2017/070339A1 |
A method of using a multi-chambered microfluidic device for enrichment of target nucleic acid sequences is provided.
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WO/2017/066692A1 |
A thermal immersion circulator can comprise a heater including a hollow cylindrical main body having an inlet opening at a first end thereof and an outlet opening in a side wall thereof. The heater can include a flexible circuit board ha...
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WO/2017/066485A1 |
A method to extract, amplify and separate nucleic acid in a microfluidic device having a plurality of chambers and channels can include a) introducing cells having nucleic acid to a first chamber of the microfluidic device and subjecting...
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WO/2017/055791A2 |
A nucleic acid amplification (NAA) reaction vessel comprising: two opposing major walls; a minor wall system attaching the major walls and thus defining a reaction chamber having a base, the major and minor walls being formed of a therma...
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WO/2017/049416A1 |
A device for the handling and the low-temperature storage of probe tubes in tube racks comprises a low-temperature compartment (1) having insulated side and bottom walls (2, 3 ) and at least one opening (6) at a top side. The compartment...
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WO/2017/048987A1 |
A thermal block assembly for use in a biological analysis system includes a sample block, a heating and cooling element, a heat sink including a surface, the surface including a plurality of projections for engaging the heating and cooli...
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WO/2017/049230A1 |
Embodiments of the current disclosure are directed towards apparatus, methods and systems configured for dynamic flux amplification of samples in reaction vessels. In some embodiments, an apparatus comprising a reaction vessel and a heat...
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WO/2017/041031A1 |
A thermal block assembly is provided. The assembly can comprise a substrate comprising a first surface configured with a plurality of reaction sites each reaction site configured to contain a biological sample and a sample block comprisi...
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WO/2017/040745A1 |
The systems and methods described herein provide a SmartTube collection and logging technique of a patient's (or clinical trial participant/subject) action of self-collection of a biologic sample during a sample collection event. The sys...
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WO/2017/025984A1 |
The current invention consists of a portable handheld device for amplification of nucleic acid followed by detection and processing of the test results on a smart phone. The smartphone interfaced temperature module enables isothermal amp...
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WO/2016/196210A9 |
Sample carrier includes a thermal-control block having an active surface and an outer surface that face in opposite directions. The active surface has a series of mounting areas that are distributed along a length of the thermal-control ...
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WO/2017/019768A1 |
An LED-driven optical cavity PCR system and method is disclosed for fast, accurate and reliable PCR based diagnostics. An optical cavity comprising two thin light absorbing metal (AU) films is used for uniform light absorption and subseq...
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WO/2017/015640A1 |
Thermal control devices adapted to provide improved control and efficiency in temperature cycling are provided herein. Such thermal control device can include a thermoelectric cooler controlled in coordination with another thermal manipu...
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WO/2016/209731A1 |
A disposable test card configured to accept a fluid sample for an assay, and a method of manufacturing same, is disclosed herein. In a general example embodiment, a test card for analysing a fluid sample includes a first substrate layer ...
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WO/2016/198582A1 |
The present invention is based on the discovery of sensitive and specific methylation detection by a) controlling excessive DNA degradation prior to conversion by incubating DNA conversion reagent (e.g. bisulfite reagent) directly with a...
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WO/2016/186312A1 |
A PCR device, according to one embodiment of the present invention, comprises: a sample sampling unit which accommodates material for DNA synthesis and is disposed in a fixed state; and a temperature adjusting unit which is disposed so a...
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WO/2016/175643A1 |
Provided is an integrated sample concentrator comprising a sample concentrating unit for concentrating a sample and a nitrogen and air generation unit provided below the sample concentrating unit. The sample concentrating unit comprises:...
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WO/2016/171474A1 |
The present invention normally relates to a method for analyzing a biomolecule and, more specifically, to: a ligand-nucleic acid analysis method, kit, apparatus and system for analyzing one or more biomolecules through a nucleic acid ana...
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WO/2016/162451A1 |
The present invention relates to a system and method for transporting frozen samples. More particularly the system and method preserves the low temperature of the samples during transport without requiring active cooling to take place. B...
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WO/2016/163956A1 |
A fluidic chip comprising: a sealing layer having an upper surface and a lower surface; and a formed part comprising a generally planar body having a lower surface sealed with the upper surface of the sealing layer, the generally planar ...
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WO/2016/163957A1 |
A digital PCR device comprising: a discrete heating area made of a heat conductive material disposed on a surface that is electrically non-conductive, the discrete heating area comprising a plurality of integral wells configured to conta...
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WO/2016/160442A1 |
A method and device for warming biological samples utilizes a heater and an outer chamber fabricated from a thermal regulating material. The outer chamber includes an outer surface and an inner surface with the heater being in operative ...
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WO/2016/145573A1 |
A heating device (1) and a biochemical reactor (2) having the heating device (1) are disclosed. The heating device (1) comprises an upper board (10), a lower board (20), a middle board (30) and an electric heating member (40). Heating ho...
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WO/2016/142516A1 |
The invention relates to a container for processing and storing biological specimens, which container has a base, a side wall, and an opening, wherein the container has a capacity from 100 μΙ to 5000 μΙ, wherein the opening is arrang...
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WO/2016/145361A1 |
A kit for optional use with a PCR method of amplification may include at least one reaction well, and an internal amplification control for a PCR amplification of an APS reductase gene having a sequence complementary to at least one sequ...
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WO/2016/145360A1 |
Aspects of the present disclosure relate to DNA amplification systems, e.g., PCR chips used to hold a testing solution and sample, and systems and methods for testing the sample including thermocycling and detection. The system can inclu...
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WO/2016/143995A1 |
In accordance with an embodiment of the present invention, provided are a multiplex PCR chip, and a multiplex PCR device comprising the same. The chip comprises: a plurality of probes for use in hybridization reactions, which are specifi...
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WO/2016/139443A1 |
A process and apparatus for the multiplexed detection of nucleic acid targets directly from samples containing blood by quantitative real-time PCR means. The process comprises the addition of blood directly into the PCR reaction, includi...
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WO/2016/133321A1 |
The present invention relates to a microparticle for a bioassay and a method for manufacturing the same, using mask patterning, spotting and imprinting processes, wherein the bioassay has a probe area and an encoder area, which are not s...
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WO/2016/131536A1 |
The invention relates to a microfluidic device (400) for the temperature-controlled processing of a sample solution (410) having a reaction chamber (450), in which the sample solution (410) can be heated to a target temperature close to ...
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WO/2016/131538A1 |
The invention relates to a microfluidic cartridge (100) for detecting biomolecules in a sample solution, comprising a detection chamber (140) to which the sample solution can be supplied via a feed channel (124), and from which the inves...
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WO/2016/124907A1 |
Instrument for performing a diagnostic test on a fluidic cartridge A cartridge reader is for carrying out a diagnostic test on a sample contained in a fluidic cartridge inserted into the reader. The fluidic cartridge comprises a fluidic ...
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WO/2016/124908A1 |
A cartridge reader controlled by processing means for carrying out a diagnostic test on a sample contained in a fluidic cartridge comprises a mechanical valve for isolating the sample with the cartridge. A system for actuating the mechan...
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WO/2016/127107A2 |
A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of ...
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WO/2016/120224A1 |
A tissue sample that has been removed from a subject can be evaluated. A transporter system for carrying a tissue sample includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or main...
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WO/2016/117726A1 |
A cartridge includes a plurality of reagent chambers, a discard chamber, a PCR chamber, and a piston provided with a channel in which a first path and a second path are provided, wherein the first path is used to move a reagent between t...
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WO/2016/117958A1 |
A temperature adjusting device for DNA analysis equipment comprises a lower heater and an upper heater. The lower heater comprises: a plurality of mounting holes which are arranged side by side along a plurality of columns on the upper p...
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WO/2016/117957A1 |
A portable real-time DNA analyzing apparatus comprises a lower box module and an upper box module. The lower box module has a mounting part which is stored in a lower housing so as to be exposed to the upper part, and has a tube holding ...
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WO/2016/115457A1 |
Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro...
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WO/2016/110292A1 |
The invention relates to a temperature control arrangement comprising a combination heat exchanger (21) for heating and cooling a measurement plate (3) of a measurement device (1), wherein the measurement plate (3) is designed to accommo...
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WO/2016/110291A1 |
The invention relates to a temperature-control assembly for measuring devices (1), which is characterized in that the specimen (2) is arranged on a measurement plate (3), wherein the measurement plate (3) can be heated by means of a heat...
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WO/2016/105073A1 |
One embodiment of the present invention relates to a PCR apparatus comprising a repeated sliding means and a PCR method using same. According to the present invention, the throughput of samples can be increased by simultaneously, rapidly...
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WO/2016/097429A1 |
The invention relates to a disposable device for carrying out a plurality of identical simultaneous microfluidic experiments, according to a set of consecutive steps. The invention also relates to the machine that is adapted to act on th...
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WO/2016/092086A1 |
The invention relates to a method for tempering a plurality of capillaries (10) arranged on a carrier (6), wherein the carrier (6), having a length (L), width (B) and height (H), accommodates the capillaries (1) across the width of the c...
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WO/2016/091344A2 |
The invention relates to a temperature-control element (4) for a multiwell plate (1), which comprises a plurality of cavities (2) arranged in rows and columns for freezing and/or thawing biological samples. The temperature-control elemen...
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WO/2016/094460A1 |
A reinforced microplate has reinforcing members that enhance stiffness and minimize deformation of the microplate, especially thermally-induced deformation. The reinforcing members include ribs or struts that are integrally formed on a b...
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WO/2016/087873A2 |
The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and...
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WO/2016/076551A1 |
According to one embodiment of the present invention, a sealing device of a microfluidic chip and an operation method therefor are provided. The device can comprise: a support part in which the microfluidic chip is arranged; and a heat s...
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