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WO/2004/067175A1 |
A sample chamber array is provided. The sample chamber array may comprise at least one reservoir in fluid communication with at least one sample chamber, and a movable portion defining the sample chamber. The reservoir is fillable with a...
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WO/2004/062778A2 |
A modular reactor system comprises a backplane connected to a computer and a thermal control unit. The backplane includes a plurality of seats for releasably holding a plurality of modules. Each module holds a reactor vessel that may be ...
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WO/2004/062806A1 |
The invention relates to a reaction chamber system (10, 70) for processing samples, comprising a reaction chamber (12), a sample carrier (26) arranged at least in the reaction chamber (12). When in operation, said sample carrier can be d...
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WO/2004/061085A2 |
Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of dense arrays of a variety of fluid ...
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WO/2004/058405A1 |
Devices including resealable film (40) used to define the volume of one or more process chambers (50) in a sample processing device (10) are disclosed. The resealable films provide for controlled puncture, followed by resealing of the pu...
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WO/2004/056485A1 |
A holder for a microtitreplate or an array of separate test tubes comprising a first panel (1) provided with a recess (2) for receiving each well (3) of the microtitreplate or test tubes and a second panel (7), which together with the fi...
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WO/2004/055199A2 |
The present invention is directed to a method for screening bloodand blood products that utilizes a specialized blood and blood p roducts storage device useful for storing and testing blood or blood products comprising a container having...
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WO/2004/055198A2 |
A device for in-line blood screening and testing using biochips is disclosed. The screening methods include nucleic acid amplification techniques and antibody/antigen assays to detect target molecules and agents indicative of infectious ...
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WO/2004/054716A1 |
The invention provides a fluid sample heating and/or cooling device comprising - a means for receiving a plurality of sample vessels, - a plurality of voids (4), each positioned to correspond with or enclose a corresponding sample vessel...
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WO/2004/052527A1 |
The invention relates to a particular DNA amplification carried out by the principle of the polymerase chain reaction in one or a number of preferably miniaturised reactors and optionally the arrangement thereof as an array. The above pe...
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WO/2004/048528A2 |
The invention provides sampling methods and apparatuses that permit the quantitative analysis of nucleic acid amplification reactions. Quantitative information garnered during an amplification regimen permits the development of a detaile...
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WO/2004/046316A2 |
A method and apparatus for facilitating molecular associations. The method involves use of independently controlled temperature zones; simultaneously promoting optimized reaction and optimized maintenance of reaction components, while al...
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WO/2004/046842A1 |
A system and method of incubating a liquid (68) is provided. The system is well-suited for incubating small volumes of liquid (68) at high temperatures. The liquid may be a reaction mixture comprising a glycoprotein. During the incubatio...
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WO/2004/045774A1 |
The invention relates to rotor means (5) for centrifuging reaction vessels containing reaction mixtures in a device for asymmetric heating and cooling of reaction mixtures during centrifugation. The rotor means (5) comprise/-s at least o...
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WO/2004/045772A2 |
A reaction vessel (10), typically a microtitre vessel. incorporating heating means (13) for effecting the reaction and having a lid (20) with a window (22) for enabling interrogation of the contents of the vessel (10), the arrangement be...
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WO/2004/046719A1 |
The invention the subject of this application relates to a device performing binding assays. In particular, the invention relates to a centrifugal device (1) for performing such assays. The invention also relates to a method of performin...
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WO/2004/045771A1 |
Rapid mixing and homogenisation of reaction mixtures with respect to temperature and chemical concentrations, as well as greatly enhanced mass transport is achieved when the reaction mixture placed in a vassel suitable for centrifugation...
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WO/2004/046712A2 |
The present invention relates to cell separation using microfabricated devices (Figure 2). In particular, the present invention provides methods and devices for separation of sperm from biological materials, such as other cells and molec...
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WO/2004/044243A1 |
In amplifying a nucleic acid, the cost is cut down by lessening the amount of a labeled or modified oligomer to be used therefor and detection can be carried out within the detection limits without resort to any treatments such as diluti...
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WO2001073417A9 |
Analytical systems and methods that use a modular interface structure (600) for providing an interface between a sample substrate (630) and an analytical unit (610) where the analytical unit (610) has a particular interface arrangement f...
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WO/2004/042086A1 |
Processes and apparatus for performing fast, precise, and reliable gas jet thermocycling on a sample using of pressurized gases delivered to a thermostated reaction chamber at high velocity using computer controlled electronic multiport ...
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WO/2004/042368A1 |
The invention relates to a carrier (10) for at least one sample chamber (11), especially for the cryopreservation of biological samples. Said carrier comprises a holding frame (20) which is used to position the sample chamber (11) and co...
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WO/2004/040645A1 |
Microfluidic devices are a promising new tool for studying and optimizing (bio-) chemical reactions and analyses. Many (bio-) chemical reactions require accurate temperature control, as for example thermocycling for PCR. Here, a new inte...
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WO/2004/038424A1 |
A temperature control method for controlling the temperature of liquid components held in an analyzing instrument (1) to a target temperature, the analyzing instrument (1) and an analyzing apparatus (X) suitable for increasing the temper...
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WO/2004/038042A1 |
A kind of 4-dimensional method of detecting nucleic acid hybrid pair on the gene chip and its relative equipment, the said method introduces the temperature parameter on the basis of traditional 3-dimension parameter detection of nucleic...
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WO/2004/035213A1 |
A thermalcycler for processing a sample holder includes a first thermalcycler body with a first face and a second thermalcycler body with a second face. A cavity for receiving the sample holder is formed in at least one of the first face...
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WO2004018704A9 |
This invention is directed to a method and apparatus using polymerase chain reaction (PCR) technologyfor collecting air samples and identifying biological agents in the air sample. The apparatus is capable ofdetecting transient events su...
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WO/2004/033099A2 |
The present invention relates to methods and systems for rapid multiplexed heating of a plurality of small volume samples on a microchip (200). More specifically, the present invention relates to methods and systems for non-contact tempe...
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WO/2004/031342A1 |
A flexible heating cover assembly (200) for an apparatus for heating samples of biological material with substantial temperature uniformity includes a housing having a plurality of engageable enclosure components; a resistive heater (300...
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WO/2004/029195A2 |
This invention relates to a portable thermocycler (10) having a unique geometric configuration, which allows the device to be made durable, compact and adapted for field-use. In general, the device includes a case (100), a rotary plate (...
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WO/2004/027023A2 |
The present invention is a metal block for use in a high throughput RNA laboratory comprising a plurality of wells, each well having an open cylindrical upper end and a closed conical lower end. Each well is design to accommodate a biolo...
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WO/2004/025247A2 |
A thermal cycling device (10) for thermally cycling samples of biological material contained in a microcard (12) having a top and bottom surface. The thermal cycling device (10) can include a sample block (34) having an upper surface con...
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WO/2004/024330A2 |
A thermal engine for a thermocycler, the thermal engine comprising a first heating and cooling element, a sample holder receiver in thermal contact with the first heating and cooling element, and a second heating and cooling element situ...
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WO2003029397A9 |
The invention relates to an apparatus and methods for preventing condensation on the interior surfaces of sample tubes which are being exposed to temperature cycles, such as during a PCR amplification reaction. In particular, the inventi...
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WO/2004/018105A1 |
A thermal engine for a thermocycler, the thermal engine comprising an electrically-controlled heating and cooling element, a heatsink and a heating and cooling stage in thermal contact with the heating and cooling element, the heating an...
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WO/2004/016948A1 |
The invention makes available methods and devices for handling liquids in micro channel systems by means of bubbles generated by a movable light beam. In particular the devices relate to pumps, valves, mixers and thermal reactors in micr...
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WO/2004/012857A1 |
An assembly and method for performing parallel chemical experiments, in particular crystallisation experiments. The assembly has a main body having a first and a second face on opposite sides thereof. Multiple bores extend through said m...
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WO2003054513B1 |
A device is provided in which a carousel is provided for use in such biochemical and chemical processes as polymerase chain reactions, using the centrifugal force resulting from rotation of the carousel to motivate fluid movement through...
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WO/2004/011666A2 |
Microfluidic devices are provided that are adapted to retain reactants in first and second chambers that can be in openable fluid communication with each other. The reactants can be reactants necessary to initiate, promote, or catalyze a...
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WO/2004/011925A1 |
A base sequence detecting device comprising a channel (601) disposed on a base sequence detecting chip (21), extended in the direction of the flow of a chemical or air, and defined by a chip cartridge upper lid (112) and a sealant (24a),...
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WO/2004/010760A2 |
Microfluidic devices, assemblies, and systems are provided, as are methods of manipulating micro-sized samples of fluids. One such embodiment of the device (498) comprise a filter frit material (412) in column (406) chamber (413), gel fi...
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WO/2004/009239A1 |
A heated platen assembly for use in a biological testing device is disclosed having a heated platen defining a plurality of optical openings configured to permit radiation to pass through the heated platen, a light transmissive slip cove...
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WO/2004/007079A1 |
A rotatable sample disk configured for samples of biological material. The sample disk may include a fill chamber for storing a first biological material, a plurality of first sample chambers positioned in the sample disk farther from th...
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WO/2004/004904A2 |
A device (10, 110, 210, 310, 350, 410) is provided for receiving a fluid sample (56). The device (10, 110, 210, 310, 350, 410) includes a fitment (14, 114, 214, 314, 414) having a cavity (18) formed therein. The cavity (18) is provided u...
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WO/2004/005507A1 |
A container for carrying out a polymerase chain reaction, which container comprises a base plate and, superimposed thereon, a cavity and flow path grooves. The flow path grooves are provided at least so as to be separated by a partition ...
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WO/2004/003444A1 |
Disclosed is a method of changing the temperature of a liquid sample, comprising: providing a receptacle having inner and outer walls defining an annular portion therebetween for receiving therein a liquid sample, inserting said liquid s...
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WO/2004/003131A2 |
A method and system are presented for use in controlling the processing of components, e.g. biological entities. Each component is assigned with a unique machine readable identification mark. Data records are provided representative of m...
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WO/2004/001376A2 |
An apparatus for expression profiling analysis, subjecting biological materials to polynucleotide extraction, amplification and analysis. The apparatus include an amplification device which permits the amplification of polynucleotides an...
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WO/2003/106612A1 |
It is an object to provide a reaction vessel that, after a reaction has been conducted with a cover attached to a reaction vessel main body, allows a reaction product contained in the reaction solution in the reaction vessel to be taken ...
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WO/2003/106033A1 |
A reaction chamber assembly comprising a e.g. microscope slide or any other slide or carrier system and an assembly cover is described, wherein said assembly cover comprises at least one port and at least one channel having a first end a...
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