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WO/2006/009308A1 |
Disclosed is a curable composition having good adhesiveness and being suitable for liquid crystal displays which hardly contaminates a liquid crystal material or an alignment film and the like as peripheral members and thus enables a liq...
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WO/2006/005436A1 |
The invention relates to a method for producing enantiomeric form of 2, 3-diaminopropionic acid derivatives of formula (I) by asymmetric hydrogenation from compounds of formula (II).
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WO/2006/003923A1 |
Disclosed is an excellent LXR modulator. Specifically disclosed are compounds represented by the following general formula (I). (In the formula, R1 represents -COR9 (wherein R9 represents an alkyl, an optionally substituted alkoxy or an ...
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WO/2006/000845A1 |
A process is described for the preparation of carbamates of primary and/or secondary polyamines, which process comprises the steps vaporising a primary and/or secondary polyamine and reacting said vaporised primary and/or secondary polya...
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WO/2005/120477A2 |
Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficie...
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WO/2005/118523A1 |
A compound of formula (I) wherein R1, R2, R3, Ra and R5 are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.
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WO/2005/118525A1 |
The present invention relates to a process (Mukaiyama Aldol reaction) for thepreparation of compounds of formula (I) wherein R1 is C1-4 alkyl, C3-6 cycloalkyl-C1-4 alkyl or aryl-C1-4 alkyl; R2 is C1-4 alkyl, benzyl, substituted benzyl or...
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WO/2005/119315A2 |
In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a &pgr -donor conjugated to a &pgr -acceptor through a &pgr -electron conjugated...
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WO/2005/115994A1 |
Substituted pyrazinecarboxylic acid anilide derivatives represented by the general formula (I) or salts thereof; intermediates of them; pesticides (such as insecticides and acaricides) for agricultural and horticultural use, containing t...
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WO/2005/115968A1 |
The invention relates to a novel method for producing 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride.
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WO/2005/114331A1 |
A resist composition which comprises one or more resist compounds (A) satisfying all of the requirements of (a) having, in the molecule thereof, at least one crosslinking group undergoing a crosslinking reaction directly or indirectly by...
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WO/2005/113471A1 |
A method of labeling one or the two oxygen atoms of the carboxy group of a carboxylated compound with an oxygen isotope which is either oxygen of mass number 17 (17O) or oxygen of mass number 18 (18O). The method is characterized in that...
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WO/2005/110978A1 |
The invention relates to urethane(meth)acrylates and to a process for their production which comprises transesterification of hydroxyalkyl carbamates with an (meth)acrylate of formula [CH2=CR29-CO-O-]t-R30 wherein R29 is hydrogen or meth...
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WO/2005/110973A1 |
The invention relates to substituted cyclohexyl-1,4-diamine derivatives, a method for the production thereof, medicaments containing these compounds, and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicame...
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WO/2005/107762A2 |
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
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WO/2005/108357A1 |
The invention provides highly functionalised spiro-fused lactams of formula (I) having a cyclohexane moiety with the desired number of protected or unprotected functional groups or carbonated structures, which are introduced with high st...
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WO/2005/108356A1 |
New spirolactams of formula (I) having a cycloexadienone moiety which are highly stable due to pi interactions between the W group and the dienone moiety. They are useful as UV absorbers and as intermediates for the synthesis of active b...
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WO/2005/102978A1 |
The invention relates to a method for the production of a.) aldehydes of formula (II): R1_ CHO and b.) aldehydes of formula (III): R1_ C(O) _ R2 by reacting a.) primary alcohols (R1CH2-OH) or b.) secondary alcohols (R1-CH(OH)-R2) with cy...
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WO/2005/102991A1 |
A process for the production of nonnatural amino acids represented by the general formula (C): (C) characterized by reacting a compound represented by the general formula (A3) with compounds represented by the general formulae (A1) and (...
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WO/2005/103280A1 |
A process for producing either a 3-benzamido-2-hydroxycarboxylic acid represented by 3-benzamido-2-hydroxy-3-phenylpropionic acid or a salt thereof. The process is safe and suitable for industrial production, and the target compound havi...
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WO/2005/100298A1 |
Compounds of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the com...
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WO/2005/100378A1 |
There is provided a process for the solid-phase synthesis of a polymer which comprises reacting an amine, secondary amine or hydroxyl group of a first monomer with a thioester on a second monomer wherein at least one the monomers is immo...
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WO/2005/100292A1 |
The invention relates to novel photoinitators of formulae (I), (II), (III), (IV), (V) and (VI) wherein R1 and R2 are each independently of the other C1-C8alkyl; C1-C4alkyl substituted by OH, C1-C4alkoxy, -COO(C1-C8alkyl), (C1-C4alkyl)-CO...
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WO/2005/097747A1 |
The present invention is directed to prodrugs of hydroxamic acid based histone deacetylase (HDAC) inhibitors, e.g., suberoylanilide hydroxamic acid (SAHA). The prodrugs are acylated derivatives having increased aqueous solubility and cel...
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WO/2005/095332A1 |
The invention relates to compounds of formula (1) wherein P is a protective group for the amine function of an amino acid selected from the group consisting of 9-fluorenylmethoxycarbonyl (Fmoc), 2-(4-nitrophenyl-sulfonyl-ethoxycarbonyl (...
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WO/2005/095326A2 |
Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s di...
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WO/2005/095331A1 |
An agent for binding a sugar chain to a peptide which comprises a compound represented by the general formula (I): X-Y-Z (I) wherein X is H2Z- or HS-; Y is -A1-, -A1-O-A2-, -(CH2CH2O)n-A1-, -(CH2CH2O)n-A1-O-A2-, -A1-NH-C(=O)-A2-, -A1-C(=...
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WO/2005/095335A1 |
The invention aims at providing ylide compounds represented by the general formula (1) and being useful as herbicide and a process for the production thereof, as well as at providing a process for the preparation of halomethyl ketones kn...
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WO/2005/095330A1 |
Formula (I), wherein X represents a group -O-A1- or a group -N=A2-, Y represents a single bond, O or S, or X and Y together may represent O, Q represents an aryl group that may be optionally substituted, a heterocyclic group that may be ...
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WO/2005/092836A1 |
A compound of the formula (I) wherein the variables X1, X2, B, D, R1 to R7.including R3', p, y, q, and z, are as defined or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for t...
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WO/2005/090292A1 |
The invention relates to a compound having general formula (I), wherein: A is selected from among one or more X, Y and/or Z groups; X represents an optionally-substituted methylene group; Y represents a C2-alkenylene, optionally substitu...
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WO/2005/089269A2 |
Substituted phenol derivatives of Formula (I) are useful as antiproliferative agents including, for example, anticancer agents, and as radioprotective and chemoprotective agents.
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WO/2005/090281A1 |
A dental material which contains a (meth)acrylic compound represented by the general formula (1) and is excellent in adhesion and adhesion durability: (1) (c) wherein R11 represents hydrogen or alkyl; R12 represents hydrogen, optionally ...
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WO/2005/090268A1 |
The present invention provides a radiolabeled ligand which is highly selective and potent for glutamate transporters and is usable in specifically detecting the glutamate transporter. Specifically, the present invention provides a 3-[3-(...
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WO/2005/085216A1 |
An isoxazoline-substituted benzamide compound of the general formula: (1) [wherein each of A1, A2 and A3 independently represents a carbon atom or nitrogen atom; G a benzene ring, etc.; W an oxygen atom or sulfur atom; X a halogen atom, ...
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WO/2005/085179A1 |
The present invention relates to new amino acid derivatives, process for their production, their use, in particular in transplantation, and pharmaceutical compositions containing them.
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WO/2005/079378A2 |
Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.
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WO/2005/077882A1 |
A chain or cyclic oligolactate having an aminoethyl, hydroxyethyl, or carboxymethyl group in a side chain. A chain oligolactate having an aminoethyl, hydroxyethyl, or carboxymethyl group in a side chain is synthesized first. This chain o...
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WO/2005/077898A1 |
The invention relates to a compound having general formula (I), wherein: m represents 0, 1, 2 or 3; n represents 0, 1, 2 or 3; X represents an oxygen or sulphur atom or an SO or SO2 group; R1 and R2 represent, independently of each other...
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WO/2005/077122A2 |
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
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WO/2005/075426A1 |
The present invention relates to novel dipeptidyl peptidase IV (DPP-IV) inhibitors or general formula (1) useful for treating diabetes, non-insulin dependent diabetes mellitus, impaired glucose tolerance, inflammatory bowel disease, ulce...
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WO/2005/073216A2 |
Compounds of the formula (F) where the variables are as defined in the specification inhibit the NS3 protease of flavivirus sych as hepatitis C virus (HCV). The compounds comprise a novel linkage between a heterocyclic P2 unit and those ...
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WO/2005/073195A2 |
Peptidomimetic compounds are described which inhibit the NS3 protease of the hepatitis C virus (HCV). The compounds have the formula where the variable definitions are as provided in the specification. The compounds comprise a carbocycli...
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WO/2005/070875A1 |
A process for the production of amines which is characterized by reacting an imine with a nucleophilic compound (except trialkylsilyl vinyl ethers) in the presence of a phosphoric acid derivative represented by the general formula (1): (...
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WO/2005/070876A1 |
An asymmetric synthesis of amino acid compound that is useful as a starting material or synthetic intermediate for production of medicinal products, agrichemicals, perfumes, functional polymers, etc. There is provided a method of enanthi...
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WO/2005/066197A2 |
The instant invention provides compositions and methods for treating a subject suffering from one of a number of conditions, including an angiogenic disease, such as cancer, an autoimmune disorder or a parasitic infection.
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WO/2005/066224A1 |
Fluoroacrylates comprise the reaction product of: (a) at least one fluorochemical alcohol represented by the formula: wherein: n = 1 to 4, R = hydrogen or an alkyl group of 1 to 4 carbon atoms, m = 2 to 8, Rf = CnF2n+1, y = 0 to 6, and q...
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WO/2005/066146A1 |
The invention relates to novel methods of preparing a thiazolo[3,4,5-de][4,1]benzothiazepine-type compound and, in particular, methanesulfonate of 6,6-dioxide of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-d
e][4,1]benzoth...
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WO/2005/063698A1 |
A process for the preparation of carbamates from organic urea and organic carbonate in presence of a solid base catalyst is disclosed. The process works at the milder reaction conditions and utilizes inexpensive catalysts that can be rec...
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WO/2005/063018A1 |
Present invention relates to a haloalkene compound of the formula (I)or its salt: wherein each of X1 and X2 is halogen; Y is alkyl, haloalkyl or phenyl; n is 0 to 5; L is -C(=B)Q, -C(=B)B’Q, -C(=B)N(D)Q, -N(D)Q, -N(D)C(=B)Q, -N(D)C(=B)...
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