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WO/2000/071244A1 |
A method of inhibiting the build-up of a contaminating material in a sulph(on)ation reaction vessel in which the surfaces of the reaction vessel exposed to the sulphonation reaction mixture are pretreated with a fluid containing a source...
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WO/2000/069808A1 |
A process for the preparation of L-carnitine inner salt comprising the reduction, with a suitable reducing agent, of a compound of formula (I): where X¿1? and X¿2?, which may be the same or different, are hydroxy, C¿1?-C¿4? alkoxy, p...
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WO/2000/066522A1 |
The present invention provides non-steroidal compounds of formula (I) which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides p...
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WO2000046235B1 |
The invention relates to novel betulinic acid derivatives of structural formula having modifications at C2, C3, C17, C20 and/or C29 positions, said derivatives being useful as inhibitors of tumor/cancer cells; process for preparation of ...
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WO/2000/064867A1 |
A product for producing and recovering sulfonated internal olefins wherein an internal olefin is sulfonated to produce a reaction mixture containing intermediate sulfonated compounds, the reaction mixture is neutralized and hydrolyzed to...
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WO/2000/061523A1 |
The invention concerns a halogenation in position meta of a phenol function. Said halogenation comprises a step which consists in halogenating an aromatic derivative of a medium or advantageously strong acid, the aromatic radical being a...
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WO/2000/058277A1 |
This invention provides compounds of formula (I) having the structure wherein Q is hydrogen or -SO¿2?R?1¿; X is a bond, O, S(O)¿n?, -CH=CH-, -CH¿2?CH¿2?-, -C$m(Z)C-, or -CH¿2?S(O)¿n?CH¿2?-; R?1¿ is OH, NH¿2?, C¿1? to C¿6? alk...
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WO/2000/058275A1 |
A water-soluble photosensitive compound which is represented by formula (1) or (2) and in which the photosensitive group gives an ultraviolet absorption spectrum having an absorption maximum wavelength of 305 nm or shorter; and a photose...
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WO/2000/058276A1 |
Formula (I) wherein: R?1¿ is a moiety selected from (a) or (b); R?2¿ is CH¿2?CH¿2?CONH¿2? or CH¿2?CH¿2?OH; R?3¿ and R?4¿ are independent substituents selected from the group including H, -N(CH¿3?)¿2?, or -OCH¿3?; or pharmaceu...
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WO/2000/056685A1 |
Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the presen...
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WO/2000/053283A1 |
A process for isolating enantiomer components from a mixture of enantiomers through co-crystallization is disclosed, comprising the steps of (a) forming a solution comprising the mixture of enantiomers (R) and (S) and co-crystallization ...
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WO/2000/051958A1 |
A process for forming 4-ketocyclopentene and substituted 4-ketocyclopentene compounds starting from the corresponding 1-carbohydroxarbyloxy-2-keto-4-hydroxy-5-cyclopentene by reduction followed by decarboxylation. The ketone may thereaft...
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WO/2000/052530A1 |
Radically photopolymerizable compositions comprising (a) at least one ethylenically unsaturated photopolymerizable compound; (b) as photoinitiator, at least one compound of formulae (I, II, III, IV, V and/or VI), wherein m is 0 or 1; n i...
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WO2000022167A9 |
Certain transcription factors (enhancer binding proteins) significantly increase transcription rates from genes by nicking a single DNA strand in the vicinity of their DNA binding sites, thereby allowing RNA polymerase to gain access to ...
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WO/2000/049028A1 |
The invention concerns a method for preparing a compound of formula (I) wherein: A represents naphthyl or phenyl optionally substituted; and Ar¿1?, Ar¿2? independently represent a saturated or aromatic carbocyclic group, optionally sub...
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WO/2000/046182A1 |
The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide (hereinafter referred to as a 'protected/activated salicylamide'). The method comprises the steps of (a) alkylat...
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WO/2000/046188A1 |
The invention relates to a method for producing alkanesulfonic acids from dialkyl sulfites, which comprises the following steps: transformation of dialkyl sulfite in the presence of a suitable catalyst in to the corresponding alkanesulfo...
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WO/2000/044710A2 |
Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF-$g(a) such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple scl...
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WO/2000/044716A1 |
Compounds of formula (B): (1a), or (1b), (1c) are provided wherein the variables are as defined herein which are useful in disease conditions mediated by TNF-$g(a), such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative c...
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WO/2000/044709A2 |
Compound of the formula (B) are useful in treating disease conditions mediated by TNF-$g(a), such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage l...
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WO/2000/044749A1 |
Compounds of formulas (a), (b), (c), or (d) are provided wherein P and Q are (e) or (f), provided that when P is (e), Q is (f), and vice versa; which are useful in disease conditions mediated by TNF-$g(a), such as rheumatoid arthritis, o...
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WO/2000/044740A2 |
Compounds of formula (I) are useful in treating disease conditions mediated by TNF-$g(a) such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
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WO/2000/044711A1 |
The invention discloses hydroxamide acids of formula (B) which are useful in treating disease conditions mediated by TNF-$g(a), such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's d...
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WO/2000/043475A2 |
The present application relates to hand dishwashing detergent compositions containing modified alkylbenzene sulfonate surfactants (MABS). These MABS comprise a mixture of specif branched and non-branched alkylbenzene sulfonae compounds, ...
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WO/2000/040529A1 |
The invention relates to the use of compounds of formula (I): wherein X is -C(O)-, -C(S)-, -C=NOH, or -CH(R?7¿)- wherein R?7¿ is hydrogen, hydroxy, C¿1-7?alkoxy, -OR?8¿ or -NR?8¿R?9¿ (wherein R?8¿ is a group -Y?1¿R?10¿ (wherein ...
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WO/2000/040551A1 |
The present invention relates to a process for forming a linear alkyl benzene sulfonate surfactant containing the steps of providing a linear alkyl benzene, providing an effective amount of an added hydrotrope precursor, combining the li...
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WO/2000/039088A1 |
Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof. The compounds act to antagonize the action of the glucagon peptide hormone.
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WO/2000/038813A1 |
Described are methods for dehydrating a hydrous substrate by combining the hydrous substrate with a hydrofluorocarbon, such as a hydrofluoroether. The process can include the step of removing water from the combined substrate and hydrofl...
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WO/2000/039072A1 |
A method for preparing a compound of formula (IXa) from a compound of formula (VIIa), and preparation of intermediates useful in the method.
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WO/2000/037423A1 |
New compounds of formula (I) are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders, where a reduction in the O-methylation of catecholami...
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WO/2000/037403A1 |
Vinyl ether compounds having the formula: R-O-X-O-CH=CH¿2?, wherein R is R¿1?-C¿n?H¿m?-, R¿1?-C¿n?H¿m?-C(=O)-, R¿1?-C¿n?H¿m?-CH[-O-X-O-CH=CH¿2?-], R¿1?-C¿n?H¿m?-CH[-O-X-O-CH=CH¿2?-]C(=O)-, R¿1?-C¿n?H¿m?-CH[-C(=O)-O-X-O-...
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WO/2000/034233A1 |
Amidoalkanesulfonic acids are prepared by reacting a molar excess of an unsaturated nitrile, a source of SO¿3?, and an olefin, in a substantially non-aqueous medium, and transferring the crude reaction product containing amidoalkanesulf...
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WO/2000/033846A1 |
The present invention relates to fungicidally effective compositions containing at least one pentacyclic triterpene compound in an agriculturally acceptable carrier.
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WO/2000/032546A1 |
The present invention is an asphaltene dispersant containing an aromatic, a sulfonic acid head, and an alkyl tail containing 16 carbons or more and at least one branch of a methyl or longer alkyl. Preferably, the aromatic is a fused two ...
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WO/2000/031028A2 |
The present invention relates to an improved process for synthesizing organic compounds for use as bleach activators.
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WO/2000/031027A1 |
The invention relates to a method of producing alkane sulfonic acid, comprising the following steps: (a) oxidizing alkyl mercaptans and/or dialkyldisulfides and/or dialkylpolysulfides having three to nine sulfur atoms with nitric acid to...
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WO/2000/029374A1 |
Benzenesulfonic acid derivatives which are utilizable as a dopant for electron-conjugated polymers and are represented by general formula (3) wherein X is hydrogen or hydroxy and R¿3? and R¿4? each is hydrogen, alkyl, etc. Examples of ...
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WO/2000/027807A1 |
This invention discloses novel polymorphic forms of 1,3 propanedisulfonic acid, disodium salt. The invention can be used to treat conditions such as peripheral amyloidosis.
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WO/2000/025770A1 |
The present invention relates to a class of carbocyclic compounds of Formula (I) that are useful as potassium channel inhibitors to treat autoimmune disorders, cardiac arrhythmias, and the like.
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WO/2000/024709A2 |
Disclosed fluoro-olefins bearing an ionic functionality or a precursor thereto, a process for the production thereof, and polymers, especially ionomers, formed therefrom, and their application for electrochemical uses.
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WO/2000/024708A1 |
A composition of matter represented by structure (I), wherein n is 2 to 6; R?1¿ and R?7¿ are each independently hydrogen, hydrocarbyl groups, hydroxyhydrocarbyl groups, alkoxyhydrocarbyl groups, aminohydrocarbyl groups, aminohydrocarby...
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WO/2000/023549A1 |
Modified alkylbenzene sulfonate surfactant mixtures comprise a mixture of specific branched and non-branched alkylbenzene sulfonate compounds, and are further characterised by 2/3-phenyl index of 257-10000. Detergent and cleaning product...
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WO/2000/023548A1 |
Modified alkylbenzene sulfonate surfactant mixtures comprise a mixture of specific branched and non-branched alkylbenzene sulfonate compounds, and are further characterised by a 2/3-phenyl index of 160-275. Detergent and cleaning product...
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WO/2000/023422A1 |
Hydrazinooxoacetamide derivatives represented by formula (I) or salts thereof, which have excellent insecticidal activity even when used in a low concentration. In formula (I), R?1¿ is chlorine or bromine: Y is oxygen or methylene, prov...
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WO/2000/022012A1 |
This invention concerns terminally unsaturated olefins of formula (III) wherein R is oxygen or an alkylene or alkylene ether group wherein one or more of the hydrogens may be substituted by halogen, and R¿f? is a radical of formula (II)...
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WO/2000/021920A1 |
Compounds of the formula (1a), wherein R1 is a group of the formula (2) where R1, R2, A, B, U, V, W, X, Y, Z, k and n have the significance given in the specification, are useful to treat rheumatoid arthritis, psoriasis, multiple scleros...
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WO/2000/020389A1 |
A compound having formula (I) wherein R?1¿ is oxo, -OR?a¿, -OC(=O)R?b¿; or (A); R?2¿ is H; or R?1¿ is -OR?c¿ and R?2¿ is -OR?d¿; or R?1¿ and R?2¿ together form -O(CH¿2?)¿m?O-; and any pharmaceutically-acceptable salt thereof ...
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WO/2000/020371A1 |
Compounds and methods for treating prostaglandin mediated diseases, and certain pharmaceutical compositions thereof are disclosed. The compounds are represented by formula (II): Ar?1¿-W-Ar?2¿-X-Q. The compounds of the invention are str...
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WO/2000/020384A1 |
A description is given of diphenyl compounds of formula (1) wherein R is a camphor or hydantoin derivative; and R¿1? is hydrogen; or C¿1?-C¿5?alkyl. These compounds are suitable as light stabilisers in cosmetic, pharmaceutical and vet...
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WO/2000/018727A1 |
Compounds represented by general formula (1) which are intermediates useful in producing oxime ether compounds being highly efficacious as agricultural/horticultural germicides wherein R?1¿ represents alkyl, alkenyl, alkynyl, cycloalkyl...
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