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WO/2023/285509A1 |
The present invention relates to a process for the preparation of a compound having formula (I) wherein R is selected from the group consisting of: halogen, (C1-C6)alkoxy, (C1-C6)alkyl, halo(C1-C6)alkyl, and halo(C1-C6)alkoxy, said proce...
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WO/2023/279995A1 |
A class of anti-bladder-cancer quaternary ammonium salt compounds and the use thereof. The quaternary ammonium salt compound is as shown in formula (I), wherein the definition of each substituent group is detailed in the description. Pro...
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WO/2023/281088A2 |
The present invention relates to a biological method for obtaining an MO monomer comprising an ethylenic unsaturation by bioconversion of a CN compound comprising at least one nitrile function, said CN compound being at least partially r...
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WO/2023/279033A1 |
Provided are novel methods of treatment of conditions such as peripheral tissue oxygenation, interstitial lung disease, dyspnea, ischemia from surgery, brain and pancreatic cancer with increased oxygen diffusivity comprising administerin...
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WO/2022/271846A1 |
Various salt and polymorph forms of Compound (I) represented by the following structural formula, and their corresponding pharmaceutical compositions, are disclosed. Particular crystalline forms of 1:0.5 Compound (I) Semi-Succinate, 1:0....
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WO/2022/263576A1 |
Cocrystal of formula APX∙Bx wherein APX is apixaban (1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)
-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
), B is a pharmaceutically acceptable carboxylic acid selecte...
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WO/2022/257025A1 |
The present application discloses a monatomically dispersed palladium-based catalyst, a preparation method therefor and an application thereof. The monatomically dispersed palladium-based catalyst comprises a main catalytic active compon...
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WO/2022/255368A1 |
The purpose of the present invention is to provide a catalyst capable of producing, with high selectivity, an unsaturated carboxylic acid and/or an unsaturated carboxylic acid ester represented by methyl methacrylate. Provided is a catal...
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WO/2022/255373A1 |
The present invention provides a method for stably obtaining a product. The present invention relates to a tank used in a refining device, characterized in that: the tank is a crystallization tank for generating a slurry that contains cr...
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WO/2022/255371A1 |
The present invention provides a method for efficiently obtaining a high quality product. A method for producing an easily polymerizable compound according to the present invention is characterized by comprising: a step for mixing an eas...
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WO/2022/255372A1 |
The present invention provides a method for stably obtaining a product. The present invention provides a purification apparatus for compounds which comprises a tank used in the purification apparatus and a hydraulic washing column, said ...
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WO/2022/255369A1 |
The present invention provides a method for obtaining a product in a stable manner. The present invention is a heat exchanger for handling a solution containing an easily polymerizable compound or a slurry containing crystals of an easil...
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WO/2022/255364A1 |
The present invention provides a method for efficiently obtaining a high-quality product. The present invention is a method for producing an easily polymerizable compound using a refining device having a crystallization tank for generati...
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WO/2022/253907A1 |
The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1
H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts....
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WO/2022/255366A1 |
The present invention provides a method for obtaining high-quality products. The present invention relates to a tank used in a refining device, characterized in that: the tank is a crystallization tank for generating a slurry that contai...
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WO/2022/250030A1 |
This method uses a heat exchange reactor, which is internally provided with a reaction tube, and produces (meth)acrolein and/or (meth)acrylic acid by means of an oxidation reaction of raw materials supplied to the reaction tube while cir...
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WO/2022/251169A1 |
Crystalline salts of psilocin are disclosed. The beneficial and therapeutic uses of the crystalline psilocin salts and of compositions containing the crystalline psilocin salts are also disclosed. The disclosure sets out methods of makin...
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WO/2022/246572A1 |
The present application relates to combination compositions comprising one or more hallucinogens, or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, and one or more fatty acids, or a pharmaceutically acceptable salt, ...
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WO/2022/237797A1 |
The present invention relates to a series of alkyl carboxylic acid compounds and an application thereof, and relates in particular to compounds represented by formula (II) and a pharmaceutically acceptable salt thereof.
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WO/2022/238389A2 |
The present disclosure relates to various crystalline forms of entinostat and to processes for their preparation, particularly Form A of entinostat compound with maleic acid, Form A of entinostat compound with succinic acid, Form B of en...
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WO/2022/237654A1 |
The present invention relates to a method for refining acrylic acid, comprising the steps of: a) countercurrently contacting an acrylic process gas with a cooling liquid from the top of a purification tower and a kettle material flow of ...
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WO/2022/236127A1 |
Provided is a first process of producing an anhydride of an organic mono-acid comprising performing a transanhydridization reaction of an organic mono-acid and a thermally regenerable anhydride to produce the anhydride of the organic mon...
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WO/2022/222680A1 |
Disclosed in the present invention are a method for preparing a high-bulk-density ibuprofen spherical crystal and a product thereof. The preparation method comprises: (1) heating ibuprofen to a molten liquid state; and (2) pressurizing t...
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WO/2022/214860A1 |
The present disclosure relates to a process for recovering methacrolein from a reactor effluent stream comprising the steps of: (a) cooling the effluent stream (str1) in a quench column (4) affording a first top stream (str2) and a first...
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WO/2022/214921A1 |
The present invention relates to an improved process for the preparation of intermediate compounds used in the preparation of Antihistamine agents. The present invention specifically relates to an improved process for the preparation of ...
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WO/2022/206399A1 |
Disclosed in the present invention is a copper catalysis-based method for preparing a carboxylic acid compound by means of alcohol oxidation using oxygen as an oxidant. The method specifically comprises: in an organic solvent at a temper...
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WO/2022/204802A1 |
The present invention provides use of psychedelics to prevent and/or treat dementia. In certain embodiments, the one or more psychedelics inhibit neuroinflammation, inhibit cerebral angiogenesis, promote neuroplasticity, down regulate AP...
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WO/2022/212727A1 |
Described herein are methods for making acrylic acid from polylactic acid (PLA) or diluted lactic acid in liquid phase in an efficient manner by using an ionic liquid and an acid catalyst, wherein the ionic liquid comprises a DBU-based s...
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WO/2022/198329A1 |
Disclosed are oral veterinary suspensions for delivering supplemental iron to a neonatal animal. The oral veterinary suspensions comprise water, an iron salt that is iron fumarate, iron sulfate, or a combination thereof suspended in the ...
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WO/2022/202756A1 |
The present invention provides a catalyst which enables the achievement of a high yield of a target product such as an α,β-unsaturated aldehyde and an α,β-unsaturated carboxylic acid. The above are achieved by means of a catalyst con...
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WO/2022/202893A1 |
The purpose of the present invention is to provide a catalyst that has a high selectivity for α,β-unsaturated aldehydes, α,β-unsaturated carboxylic acids, and the like. This catalyst includes at least molybdenum and bismuth, and exhi...
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WO/2022/194590A1 |
The invention relates to a continuous method for producing methacrylic acid by catalytically hydrolyzing methyl methacrylate, which has been produced on the basis of C-2, C-3, or C-4 raw materials. In the process, methyl methacrylate wit...
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WO/2022/187235A1 |
In various embodiments, the present invention relates to a series 3D printable, biodegradable, poly(propylene fumarate) derivative ABA type triblock copolymers having a flexible propylene succinate core unit synthesized through ring-open...
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WO/2022/186032A1 |
This catalyst contains molybdenum, bismuth, and iron, wherein R1 represented by expression (1) is 0.45-5.00. R1=(maximum value of a peak at 886 cm-1±5 cm-1)÷(maximum value of a peak at 354 cm-1±5 cm-1), as measured by Raman spectrosco...
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WO/2022/187291A1 |
Acrolein is produced by selectively oxidizing iso-propanol over a first mixed metal oxide catalyst in the presence of oxygen in the vapor phase. The first mixed metal oxide catalyst comprises oxides of molybdenum and bismuth. Acrylic aci...
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WO/2022/166870A1 |
Disclosed in the present invention is a preparation method for a tetra-substituted allenoic acid compound based on a palladium catalytic system, that is, an optically active allenoic acid compound having axial chirality is directly const...
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WO/2022/163727A1 |
A catalyst containing molybdenum, copper and vanadium as essential components, in which the hydrogen consumption amount (L) at a hydrogen consumption peak appearing in a range of 300°C to 500°C inclusive in a TPR (temperature-programme...
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WO/2022/163725A1 |
A catalyst including molybdenum, copper, and vanadium as essential components, wherein the peak acidity (M) appearing in the range 250°C to 420°C according to an ammonia thermal desorption method is 1.35 mmol/g to 2.00 mmol/g.
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WO/2022/163726A1 |
A catalyst that includes molybdenum, copper, and vanadium as essential components thereof and has a ratio (X/Y) of 1.10–3.00 between the volume (X) of pores having a diameter of 25–400 μm as measured by mercury intrusion porosimetry...
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WO/2022/150603A1 |
The present disclosure relates to crystalline forms of the compound 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)yl)methyl]
benzoic acid hemifumarate, pharmaceutical compositions comprising these compounds and uses thereof to treat ...
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WO/2022/141805A1 |
An application of a crotonic acid salt in the preparation of a drug for treating a heart disease. A crotonic acid salt preparation and a method for preparing same. The method is characterized by comprising: mixing a crotonic acid solutio...
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WO/2022/136227A1 |
There is provided a method for preparing homofarnesol (1), the method comprising the steps of: a) providing homofarnesylnitrile (2); b) reacting homofarnesylnitrile (2) to homofarnesic acid (3); and c) reacting homofarnesic acid (3) to h...
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WO/2022/132443A1 |
A method for preparing methacrylic acid from methacrolein. The method comprises contacting a liquid mixture comprising methacrolein and water in the presence of oxygen with a heterogeneous catalyst comprising a support and gold; wherein ...
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WO/2022/132442A1 |
A method for preparing acrylic acid from acrolein. The method comprises contacting a liquid mixture comprising acrolein and water in the presence of oxygen with a heterogeneous catalyst comprising a support and gold; wherein the support ...
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WO/2022/120615A1 |
Provided is a production process for fumaric acid. The production process comprises the following steps: carrying out a decoloration treatment by using activated carbon, filtering, and adding same into a reaction kettle; carrying out a f...
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WO/2022/119125A1 |
A process for preparing acrylic acid of the present application comprises: a first step of adding (or not adding) a first absorbent to a reaction product of a bio-material and cooling the reaction product to separate a first low-boiling-...
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WO/2022/119126A1 |
The present application relates to a process for producing acrylic acid.
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WO/2022/119127A1 |
The present invention provides a method for producing acrylic acid, wherein the method for producing acrylic acid comprises the steps of: feeding lactic acid to a reactor and preparing a reaction product containing acrylic acid by a dehy...
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WO/2022/119123A1 |
The present application relates to a process for producing acrylic acid, wherein the process comprises a first step and a second step in which a first absorbent is added to a reaction product of a bio-material and cooled to separate a fi...
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WO/2022/118309A1 |
A process for the preparation of cis-2-alkenoic acid or an alkali metal salt thereof, comprising rearranging 1,3-dibromo- 2-alkanone in an alkaline environment in the presence of a catalytically effective amount of an alkali metal salt o...
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