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Matches 1 - 50 out of 3,737

Document Document Title
WO/2021/056324A1
Provided is a green chemical preparation method for alpha-tri-O-acetyl glucuronic acid methyl ester bromo compound. The method uses sodium bromide, sulfuric acid and methyl tertiary ether system to replace the traditional hydrobromic aci...  
WO/2021/046497A3
This disclosure is directed to a pharmaceutical composition comprising a bioactive agent (active pharmaceutical ingredient, API) and at least one long chain fatty acid (LCFA), wherein the long chain fatty acid can comprise a carbon chain...  
WO/2021/056382A1
Provided is a preparation method for alpha-penta-O-acetyl mannose. A study is performed using natural mannose as a raw material on the basis of the conventional acetic anhydride acetylation process. A catalytic amount of cesium fluoride ...  
WO/2021/055933A1
The present disclosure relates to disaccharides with defined sulfation patterns, and oligosaccharide mimetics comprising the disaccharides as repeating units linked in a head to tail fashion. The present disclosure further relates to met...  
WO/2021/050778A1
The present disclosure provides compositions and methods for enhancing immune response in a subject. In an embodiment, this disclosure provides modified LPS molecules and compositions comprising the modified LPS molecules. The disclosure...  
WO/2021/042922A1
Disclosed is a preparation method for tetragalloylglucose. The method comprises: using Camellia ptilophylla Chang as a raw material for extraction, purifying the Camellia ptilophylla Chang extract by using a macroporous adsorption resin,...  
WO/2021/022565A1
A sucrose fatty acid ester, a preparation method and a quantitative analysis method therefor, and an application thereof. The preparation method comprises the following steps: (1) adding sucrose, a fatty acid methyl ester, a catalyst, an...  
WO/2021/022819A1
The present invention relates to an isomerization feature-based purification and preparation method of punicalagin. The method uses a pomegranate peel extract as a raw material, avoids impurities contained in punicalagin on the basis of ...  
WO/2021/019509A1
The present document relates to a process for the preparation of the crystalline form II of sotagliflozin from compound of formula (A), said process being continuously performed and comprising at least the steps of: a) performing in a re...  
WO/2021/019507A1
The present document relates to a process for the preparation of the crystallineform II of sotagliflozin, wherein said crystalline form II of sotagliflozin is directly obtained from the following compound of formula (A) and by using tolu...  
WO/2021/013155A1
Disclosed are a new glycosyl donor, a preparation method therefor, and an application thereof. Specifically, a glycosyl donor represented by formula (I), a preparation method therefor, and a use of the glycosyl donor represented by formu...  
WO/2021/000041A1
The present document describes compounds, or pharmaceutically acceptable salt thereof, of a core formula (I) Wherein R1 includes an amino group. These compounds are particularly useful in the formulation and in vivo and ex vivo delivery ...  
WO/2020/248068A1
The present application provides a synthetic method for production of 3-azido-3-deoxy-D-galactopyranose. Also provided are methods of using the 3-azido-3-deoxy-D-galactopyranose in the manufacture of galactoside galectin antagonists, suc...  
WO/2020/228436A1
The present invention relates to aromatic ring or heteroaromatic ring derivatives, a preparation method therefor and applications thereof in medicine. Specifically, the present invention relates to aromatic ring or heteroaromatic ring de...  
WO/2020/183442A3
The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicr...  
WO/2020/211668A1
Disclosed are compounds that are inhibitors of CD73 and are useful in treating CD73-associated diseases or conditions, and compositions containing the compounds.  
WO/2020/202790A1
The purpose of the present invention is to provide: a novel compound which has an antioxidative effect; and use of the compound. The present invention achieves the above-described purpose by providing a compound represented by formula (1...  
WO/2020/183442A2
The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicr...  
WO/2020/178798A1
The present disclosure describes acyl halide liquid dispersions and tunable methods of treating cellulosic materials with compositions that provide increased hydrophobicity and/or lipophobicity to such materials without sacrificing the b...  
WO/2020/106870A3
Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides. The yeast cells include one or more heterologous nucleic acids that encode enzymes of a human milk oligosaccharide biosynt...  
WO/2020/140559A1
Provided is a 5-deoxy-D-ribose derivative (III), when the derivative (III) is used for preparing capecitabine, the stereoselectivity is good and the yield is high. Further provided is a preparation method of the derivative, wherein the p...  
WO/2020/132625A1
Methods for the preparation of oligosaccharide products from polysaccharide starting materials are disclosed. The methods include: hydrolyzing a glucosamine-containing polysaccharide starting material, such as heparin or heparosan, under...  
WO/2020/132096A1
The invention provides methods for preparing antibodies and antibody derivatives with controlled levels of core fucosylation. In one aspect, provided herein is a method of controlling the level of afucosylation of an antibody or antibody...  
WO/2020/106870A2
Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides. The yeast cells include one or more heterologous nucleic acids that encode enzymes of a human milk oligosaccharide biosynt...  
WO/2020/087499A1
Disclosed is a method for preparing a flame retardant silk, the method comprising the following steps: soaking silk in a tannic acid solution with a pH value of 3-4, and raising the temperature to 80-90℃ for a temperature holding treat...  
WO/2020/083733A1
The present invention relates to the compounds of formula (I), and the N-oxides, stereoiso- mers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variablesare defined according to the description, (I) Th...  
WO/2020/082162A1
An adjuvant formulation includes a monophosphoryl Lipid A (MPLA) analogue, a Pam3CSK4 analogue, or a muramyldipeptide (MDP) analogue, or combinations thereof. The adjuvant may be formulated in soluble form or in a nanoparticle, such as p...  
WO/2020/078807A1
The present invention relates to a prodrug compound of the general formula I or II. The prodrug compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3...  
WO/2020/078808A1
The present invention relates to a compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in ...  
WO/2020/064787A1
The present disclosure relates generally to terpene glycosides, such as certain such compounds extracted from Stevia rebaudiana Bertoni, Rubus suavissimus, or Siraitia grosvenorii. The disclosure also provides for the use of such compoun...  
WO/2020/068235A1
A method of treating cellulosic materials with a barrier coating comprising at least two polyol and/or saccharide fatty acid ester, having different HBL values, that provides increased water, oil and grease resistance to such materials w...  
WO/2020/068582A1
An alkyd polymer composition for fast-drying, low VOC applications is provided. The alkyd polymer incorporates a minimum required level of a cyclic ether- and hydroxyl-containing composition formed from a sugar alcohol during the alcohol...  
WO/2020/064788A1
The present disclosure relates generally to terpene glycosides, such as certain such compounds extracted from Stevia rebaudiana Bertoni, Rubus suavissimus, or Siraitia grosvenorii. The disclosure also provides for the use of such compoun...  
WO/2018/213824A3
Therapeutics and methods of treating an angiogenesis related pathology in a mammal comprising administering a therapeutically effective dose of a pharmaceutical composition containing a first therapeutic, wherein the first therapeutic bi...  
WO/2020/058889A1
The present patent application relates to the use of an innovative amino acid derivative of glucosamine having the Formula 1 of the general structure which follows, or of a pharmaceutical composition which contains it as a single active ...  
WO/2020/056124A1
The present invention describes tunable methods of treating cellulosic materials with a barrier coating comprising a prolamine and at least one polyol fatty acid ester that provides increased oil and/or grease resistance to such material...  
WO/2020/032272A1
The present invention provides a production method for sugar fatty acid esters. The production method is characterized in that a weakly basic ion exchanger that has a pKb of 3–7 is used as a catalyst to react a fatty acid ester and a s...  
WO/2020/025693A1
Compositions containing monoester derivatives of the primary alcohol residue of a sugar are generally disclosed herein, as well as their use as sweetness enhancers, bitterness maskers, sourness maskers, or astringency reducers, to improv...  
WO/2020/027882A1
Disclosed herein is a method of producing high purity pentagalloyl glucose (PGG), analogues or derivatives thereof, at least 99.9% pure, by washing with dimethyl ether. PGG may be provided in a kit, including a hydrolyzer for dissolving ...  
WO/2020/015612A1
A fucosylated chondroitin sulfate oligosaccharide having the structure as shown in J, and further disclosed is a method for preparing the fucosylated chondroitin sulfate oligosaccharide: using a chondroitin sulfate A salt as a raw materi...  
WO/2020/014669A1
Thrombin-inhibiting acylated pyrazole-pyridone compounds of formula (II) are disclosed herein, as well as pharmaceutical compositions, including tablets, that contain acylated pyrazole- pyridone compounds. These compounds are useful for ...  
WO/2019/230978A1
The present invention provides a tannic acid based surface-active compounds, a method of producing tannic acid based surface-active compounds and a dispersing composition including the Tannic acid based surface-active compounds. Consider...  
WO/2019/228408A1
Provided herein are potent compounds of Formula (I) and uses thereof for inhibiting the activity of D-amino acid oxidase (DAAO) or treating diseases or disorders associated with DAAO, such as a central nervous system (CNS) disorder, pain...  
WO/2019/227525A1
An application of a chitooligosaccharide-based compound as a biomaterial, especially as a fluorescent molecule carrier. The chitooligosaccharide-based compound has a structure represented by formula (I) with chitooligosaccharide having d...  
WO/2019/230979A1
The present invention provides a method of dispersing asphaltene contained in crude oil and method of dispersing asphaltene contained in asphalt cement. Considering the importance of renewable surfactants for long-term sustainable develo...  
WO/2019/227228A1
The present disclosure relates to analogs of N-acetyl glucosamine fluorinated at 4- and/or 6-position(s) and derivatives of xylose at anomeric position for the treatment of a neurological disease, inflammation, cancer and a central nervo...  
WO/2019/230980A1
The present invention provides a method of dispersing crude oil emulsion containing a tannic acid based surface-active compounds. Considering the importance of renewable surfactants for long-term sustainable development we have developed...  
WO/2019/223485A1
A method for synthesizing sucrose-6-ester. The method comprises: (a) in the presence of a polar aprotic solvent, contacting an organic phosphine compound represented by formula I with sucrose and an organic tin compound; (b) removing wat...  
WO/2019/222424A1
Disclosed are cationic lipids which are compounds of Formula (I'). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly...  
WO/2019/197595A3
The invention relates to compounds of formula (I) and their use in eliciting a pro-Thl7 immune response. Further provided are methods of production of said compounds. (Formula I) wherein m is an integer between 4 and 13; n is an integer ...  

Matches 1 - 50 out of 3,737