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Matches 1 - 50 out of 1,422

Document Document Title
WO/2021/027306A1
Disclosed is a conjugate obtained by condensing dihydroartemisinin and a steroid, as represented by the following general formula (I), or an isomer, pharmaceutically acceptable salt, or prodrug molecule thereof; wherein the hydroxy group...  
WO/2021/012424A1
Disclosed is a method for preparing a high-content mogroside monomer product, the method comprising the following steps: (1) performing dispersion and dissolution; (2) performing precipitation and precision filtration; (3) performing dil...  
WO/2020/264512A1
Provided herein in part is a compound of Formula (I): or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of Formula I, and methods of using the compounds, e.g, in the treatment of CNS- relate...  
WO/2020/251346A1
The present invention describes a naturally occurring chemical compound, specifically guayalins A, B, C and D used in medicine having null cytotoxicity and genotoxicity on healthy lymphocyte cells. Said active compounds interfere with th...  
WO/2020/243488A1
Provided herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7a, R7a, R11a, R11b, R12a, R12b, R16a, R16b, R19, R11a, R22, RX, RY and n are defined he...  
WO/2020/223174A1
Provided are androstane and dihydrotestosterone compounds functionalized with carbocyclic groups or heterocyclic groups that may be saturated or unsaturated. The compounds may be used in methods of inhibiting cell growth of malignant cel...  
WO/2020/205922A1
The present invention includes compounds having structural formula (I), wherein R1-R9 are as defined herein, or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes composit...  
WO/2020/201446A1
The present disclosure generally relates to various formulations and uses of the compound Isomogroside IVE. In some aspects, the disclosure provides compositions that include Isomogroside IVE. In some embodiments, the compositions are co...  
WO/2020/200916A1
The various aspects presented herein relate to processes for preparing food ingredients, flavors and sweeteners from extracts of plants that contain mogrosides such as Siraitia grosvenorii. Further provided herein are formulations and us...  
WO/2020/177153A1
The present invention belongs to the technical field of medicine, and provides a pharmaceutical or health food composition of nicotinamide mononucleotide and mogroside. In addition, the present invention also provides a preparation metho...  
WO/2020/176668A1
Monk fruit extracts containing mogrol glycosides such as mogroside V may be treated with enzymes under specific reaction conditions to shift distribution of the Siamenoside I reaction product. Modified enzymes are also employed to shift ...  
WO/2020/176602A1
Mogrosides containing non-glucose glycosides are provided herein. Compositions, including consumables comprising the novel mogrosides described herein, are also provided.  
WO/2020/169643A1
The present invention relates to the diethylamine salt of 3a- tetrahydropyranyloxy-6a-ethyl-7a-hydroxy-53-cholanic acid (I), which is a new intermediate in the synthesis of obeticholic acid, to the use of said diethylamine salt in the sy...  
WO/2020/137706A1
[Problem] The purpose of the present invention is to provide a new method for producing a cycloastragenol analog from astragaloside IV. {Solution] A method for producing a cycloastragenol analog that includes a contact step that brings a...  
WO/2020/083839A1
The present invention relates to a new process for the synthesis of 3a-hydroxy-5a-pregnan-20-one, commonly known as brexanolone, wherein the corresponding cyclic 20-ketal or cyclic 20-thioketal compound of formula (IV) is deprotected wit...  
WO/2020/056735A1
A method for improving content of malonyl-ginsenoside in a product, a product containing the malonyl-ginsenoside prepared by the method, and a kit implementing the method. The method comprises the following steps: (1) mixing a sample con...  
WO/2020/048049A1
Disclosed are a method for preparing a Luo Han Guo sweetner composition from Siraitia grosvenorii and a use thereof. The method for extracting the sweetener composition from Siraitia grosvenorii preferably comprises the following steps: ...  
WO/2020/036308A1
The present specification relates to (20S,24R)-6-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside -dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, pharmaceutically acceptable salts thereof, hydrates thereof, or so...  
WO/2020/036310A1
The present specification relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside -dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, and pharmaceutically acceptable salts the...  
WO/2019/240508A1
The present invention relates to a composition containing a novel compound isolated from an Acanthopanax sp. fruit extract. More specifically, a novel compound of the present invention can effectively inhibit blood pressure elevation, ca...  
WO/2019/219098A1
Disclosed are a panaxoside derivative, a preparation method therefor, and an application. The compound shows a strong anti-inflammatory effect in vitro and in animal model experiments, and may therefore be used for preparing an anti-infl...  
WO/2019/209803A1
Novel mogrosides and compositions comprising said novel mogrosides, including consumables, are provided herein. Methods of obtaining said novel mogrosides from either purification and/or bioconversion, are also provided.  
WO/2019/201280A1
A use of ginsenoside M1 for manufacturing a medicament for treating oral cancer.  
WO/2019/178980A1
A method for preparing gynostemma pentaphylla makino saponin LVI, XLVI, L, LI, Damulin A or Damulin B. In said method, Gynostemma cardiospermum Cogn.ex Oliv is used as a raw material to prepare a high content of target product by means o...  
WO/2019/154257A1
The present invention relates to steroid derivative regulators, a method for preparing the same, and uses thereof. Specifically, the present invention relates to a compound of formula (I), a preparation method therefor, a pharmaceutical ...  
WO/2019/154247A1
The present invention relates to steroid derivative regulators, a method for preparing the same, and uses thereof. Specifically, the present invention relates to a compound as shown in formula (I), a preparation method therefor, a pharma...  
WO/2019/129913A1
The present invention relates to compounds of formula (I) derived from ursodeoxycholic acid, to processes for preparing them and to their use for the treatment of polycystic diseases, in particular autosomal dominant polycystic liver dis...  
WO/2019/129249A1
The present invention relates to a novel use of a triterpenoid. In particular, the present invention provides a use of a compound of formula I, or an optical isomer thereof, or a racemate thereof, or a solvate thereof, or a pharmaceutica...  
WO/2019/126741A1
Provided herein are compounds of Formula (I-I): and pharmaceutically acceptable salts thereof; wherein p, R1, R3a, R2a, R11a, R11b, R6a, and R6b are defined herein. Also provided herein are pharmaceutical compositions comprising a compou...  
WO/2019/120716A1
Suggested are triiterpene-glycoside compounds, which are obtainable by the extraction of Gynostemma pentaphyllum which are useful as a sweetener or sweet taste enhancer in preparations and compositions, especially oral edible compositions.  
WO/2019/017722A3
The present invention relates to a method for producing a ginsenoside from a Gynostemma pentaphyllum-derived adventitious root. Specifically, the present invention relates to a method for producing a ginsenoside from a Gynostemma pentaph...  
WO/2019/021122A3
The present invention relates to novel Liver X Receptor (LXR) modulators, their use in diagnostic and therapy, more particularly in the treatment of diseases associated with LXR, such as cancer, inflammation, metabolic and autoimmune dis...  
WO/2019/021122A2
The present invention relates to novel Liver X Receptor (LXR) modulators, their use in diagnostic and therapy, more particularly in the treatment of diseases associated with LXR, such as cancer, inflammation, metabolic and autoimmune dis...  
WO/2019/017722A2
The present invention relates to a method for producing a ginsenoside from a Gynostemma pentaphyllum-derived adventitious root. Specifically, the present invention relates to a method for producing a ginsenoside from a Gynostemma pentaph...  
WO/2019/011010A1
The present invention relates to the field of medicinal chemistry, and specifically to a sweet potato sitosterol glycoside unsaturated fatty acid, an extract, a preparation method therefor, and an application thereof. Sweet potato sitost...  
WO/2018/220103A1
A sweetness modifying composition comprising at least one high-intensity sweetener chosen from steviol glycosides and/or mogrosides and at least one low-potency sweetener chosen from cellobiose, psicose, cyclamate and/or 11-O-mogroside V...  
WO/2018/201516A1
A compound and an application thereof for treatment of cataract. The structural formula of the compound is as shown in formula I. The compound of formula I, a prodrug thereof, or a pharmaceutically acceptable salt thereof, can be used to...  
WO/2018/196581A1
Disclosed is a dihydroartemisinin-steroid conjugate having the following general formula (I) or a pharmaceutically acceptable salt thereof, wherein the dihydroartemisinin molecule at the position 10 thereof is connected to the parent nuc...  
WO/2018/166029A1
Disclosed is a method for separating and purifying mogroside V by means of subcritical hydrolytic adsorption technology. The method desorbs a macroporous adsorption resin enriched with mogroside V under subcritical conditions for water, ...  
WO/2018/135699A1
The present invention provides a novel ergostenol glycoside derivative. The ergostenol and the glycoside derivative thereof according to the present invention suppresses the production of chemokines increasing according to the skin infla...  
WO/2018/068021A1
The present invention relates generally to compositions and methods for treating cancer and hypercortisolism. Provided herein are substituted steroidal derivative compounds and pharmaceutical compositions comprising said compounds. The s...  
WO/2018/062904A1
Disclosed are a composition for production of ginsenoside compound K using a high temperature-β-glycosidase and a high temperature-α-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producin...  
WO/2018/028144A1
The present application provides a separation and purification method for high-purity mogroside V, comprising the following steps: (1) dissolving and centrifuging: taking a Siraitia grosvenorii crude product, and adding water for dissolv...  
WO/2018/013613A1
Described herein are neuroactive steroids or a pharmaceutically acceptable salt thereof. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a comp...  
WO/2018/002897A1
The present invention concerns compounds having formula (I) and compositions thereof with a pharmacologically acceptable excipient and uses thereof as a medicament, in particular for the treatment and/or prevention of a disorder selected...  
WO/2017/211079A1
The present application relates to a technique for extracting mogroside V. Provided is a method for extracting high-purity mogroside V from Siraitia grosvenorii. The specific steps comprise: pre-treatment of a raw material, extraction, c...  
WO/2017/199033A1
The invention relates to compounds of general formula (I): wherein: R1,R2, R3, R4, R5, R6 and Y are as defined herein. The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditio...  
WO/2017/199039A1
The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein. The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis...  
WO/2017/186135A1
Disclosed in the present invention are a compound and an application thereof for the treatment of cataracts. The structural formula of the compound is shown in formula I. The compound shown in formula I, a prodrug thereof, or a pharmaceu...  
WO/2017/150723A1
Algae that generates a sterol and a sterol production method that uses the algae. According to the present invention, a sterol is produced by culturing algae, such as strain AJ7867 (FERM BP-22304) and strains derived therefrom, that has ...  

Matches 1 - 50 out of 1,422