| Document |
Document Title |
|
WO/2010/041943A2 |
The invention relates to a method for preparing ε-caprolactam comprising deacylating N-acyl-6-aminocaproic acid and forming ε-caprolactam. The deacylation may be carried out chemically or biocatalytically. The invention further relates...
|
|
WO/2010/041269A1 |
The present invention discloses an isolation and purification process for mycophenolic acid obtained from the fermentation process. Invention further discloses preparation of sodium salt of mycophenolic acid and mycophenolate mofetil fro...
|
|
WO/2010/038842A1 |
Disclosed is a compound represented by formula (I) [wherein the symbols are as defined in the description]. Also disclosed is a process for producing the compound. The compound has a lipase-inhibiting activity, and is therefore useful ...
|
|
WO/2010/034243A1 |
Novel isolated DNA sequences which comprise all or part of a gene cluster encoding sanglifehrin synthase, processing and regulatory genes involved in the biosynthesis of a mixed non-ribosomal peptide/ polyketide compound, or mutants havi...
|
|
WO/2010/030197A1 |
A method for producing an algal biomass that readily separable from water, and preferably sterile, the method comprising heating an aqueous slurry of algae comprising a mixture of an algal biomass, optionally together with a suitable sep...
|
|
WO/2010/030196A1 |
A method for processing biomass comprising heating an aqueous slurry comprising biomass, water and a phosphate catalyst in a pressure vessel at a temperature of about 150 °C to about 500 °C to produce a mixture comprising a dispersion ...
|
|
WO/2010/026873A1 |
Disclosed are: a novel compound having an excellent inhibitory activity against at least one of a neutral ceramidase and an alkaline ceramidase; a process for producing the compound; a novel microorganism capable of producing the novel c...
|
|
WO/2010/024445A1 |
An optically active amine derivative can be produced by: reacting an imine derivative with a culture or a cell of a microorganism capable of reducing the compound stereoselectively or a treatment product of the culture or the cell to the...
|
|
WO/2010/024444A1 |
A novel enzyme capable of reducing an imine derivative stereoselectively is isolated and purified, and a polynucleotide encoding the enzyme is cloned. An optically active amine derivative can be produced by: reacting an imine derivative...
|
|
WO/2010/022244A1 |
The invention provides methods and compositions for the production of L-ribitol and other rare sugars using a mannitol-1-dehydrogenase or a polyol-1-dehydrogenase.
|
|
WO/2010/012074A1 |
An isolated nucleic acid molecule cloned from Artemisia annua encodes an alcohol dehydrogenase (Adh1). Artemisia annua Adh1 enzymatically oxidizes artemisinic alcohol to artemisinic aldehyde. The nucleic acid molecule, and the enzyme enc...
|
|
WO/2010/011882A1 |
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with 1 module, and a cytochrome P450 hydroxylase is described. Also provided are novel Streptomyces species and metho...
|
|
WO/2010/010955A1 |
Disclosed are an isolated novel polynucleotide containing a nucleotide sequence for coding at least one type of polypeptide that contributes to the biosynthesis of pyripyropene A, a recombinant vector containing said polynucleotide, and ...
|
|
WO/2010/004584A2 |
The present invention provides treatment of diabetes using serpentine. The present invention particularly provides a process of production of serpentine in Catharanthus roseus hairy root culture, effect of hairy root extract in reducing ...
|
|
WO/2010/003304A1 |
Recombinant bacteria for producing deoxyviolacein and uses thereof are provided, wherein the recombinant bacteria is obtained by introducing the deoxyviolacein synthesis-related gene cluster into Escherichia coli BL21-CodonPlus (DE3)-RIL...
|
|
WO/2010/000676A1 |
The present invention relates to a method for preparing microbiologically produced ergot alkaloids of the following formula (I), comprising the step of: a) extracting the fermentation product occurring during the biological production, s...
|
|
WO/2010/000839A1 |
This invention relates to improved processes for the production of lipstatin and/or orlistat and means therefore. In particular, the invention relates to microorganisms characterized by abolished or reduced activity of the BKD complex, e...
|
|
WO/2010/000601A1 |
The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes particip...
|
|
WO/2009/151728A2 |
The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective a...
|
|
WO/2009/151530A1 |
The present invention generally relates to methods for treating tuberculosis in a subject comprising administering to the subject an antibiotic in conjunction with clavulanic acid or salt thereof. The antibiotic can be carbapenem (e.g., ...
|
|
WO/2009/147984A1 |
The nucleotide sequence for DNA involved in the biosynthesis of herboxidiene is determined. By using the DNA, it becomes possible to produce herboxidiene and analogues thereof with high efficiency.
|
|
WO/2009/142489A2 |
The present invention relates to a method for preparing α-amino-ε-caprolactam, comprising converting lysine to α-amino-ε-caprolactam, wherein the conversion is catalysed by a biocatalyst. Further, the invention relates to a host cell...
|
|
WO/2009/142490A1 |
The invention relates to a method for preparing ε-caprolactam comprising reducing the carbon-carbon double bond of (Z)-6,7-dihydro-1H-azepin-2(5H)-one, wherein the reduction is catalysed by a biocatalyst.The invention further relates to...
|
|
WO/2009/138994A1 |
The present invention demonstrates the utilization of halide anions such as iodates, periodates, bromates, chlorates, perchlorates and other forms of halides as supplements in fermentation media for the production of secondary metabolite...
|
|
WO/2009/133096A2 |
The present invention relates to a method for the identification of one or more genes of a parent microbial strain capable of producing one or more desired β-lactam compound(s) and to mutant microbial strains in which the identified gen...
|
|
WO/2009/134899A2 |
The present invention provides for a non-naturally occurring polyketide synthase (PKS) capable of synthesizing a carboxylic acid or a lactone, and a composition such that a carboxylic acid or lactone is included. The carboxylic acid or l...
|
|
WO/2009/131264A1 |
Disclosed herein is a method for preparing ortho- dihydroxyisof lavones using a biotransformation system. More specifically, disclosed is a method for preparing ortho-dihydroxyisof lavones, which comprises biotransf orming daidzein or ge...
|
|
WO/2009/130706A1 |
The present invention is successful in providing a suitable process for the isolation and purification of geldanamycin. The process provided in the instant invention is easy to scale-up, industrially safe and will give high yield and pro...
|
|
WO/2009/121495A1 |
Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.
|
|
WO/2009/118743A1 |
The invention provides a process for the production of lipase inhibitors via an improvised fermentation process characterized in that a combinatorial feeding of linoleic acid or its esters or salts thereof and an omega-9 fatty acid, pref...
|
|
WO/2009/118750A1 |
The present invention provides a stereoselective enzymatic process for the resolution of a mixture of (±)-cis-3-acetoxy-1-(4-methoxyphenyl)-4-(2-furanyl)-2- azetidinone, (±)-cis-3-acetoxy-1-(4-methoxyphenyl)-4-(2-thiophenyl)-2-az
etidi...
|
|
WO/2009/119111A1 |
Disclosed is a method for cheaply and easily producing theaflavins. After adding a large quantity of water to raw tea leaves that have not undergone wilt treatment, the tea leaves are crushed in a blender and then let stand, shaken, or a...
|
|
WO/2009/113855A2 |
The invention relates to a method for preparing 6-aminocaproic acid (hereinafter also referred to as '6-ACA')usinga biocatalyst. The invention further relates to a method for preparing e-caprolactam (hereafter referred to as 'caprolactam...
|
|
WO/2009/103534A2 |
The present invention describes Elansolids, a new class of novel anti-bacterial compounds of formula (I).
|
|
WO/2009/101959A1 |
Disclosed is a novel compound having a therapeutic and/or prophylactic activity on inflammatory diseases, lifestyle-related diseases and adult diseases. Specifically disclosed are: a compound represented by general formula (I) [wherein R...
|
|
WO/2009/102876A1 |
The invention provides compounds inhibitory to the Hepatitis C viral protease, compositions and combinations including the compounds, methods of treatment of conditions wherein inhibition of the Hepatitis C viral protease is medically in...
|
|
WO/2009/101956A1 |
Disclosed is a substance FKI-3864 which is represented by formula [I] and has an inhibitory activity on the production of triacylglycerol. Also disclosed is a method for producing the substance FKI-3864. The method for producing the subs...
|
|
WO/2009/098046A1 |
The present invention relates to a novel method for the fermentative production of dipicolinate by cultivating a recombinant microorganism expressing an enzyme having dipicolinate synthetase activity. The present invention also relates t...
|
|
WO/2009/096445A1 |
Disclosed are a neural stem cell propagation accelerator which contains a compound produced by Penicillium sp. strain CND1007 (FERM BP-10917) or a pharmacologically acceptable salt thereof, a novel compound produced by Penicillium sp. st...
|
|
WO/2009/092702A2 |
The present invention relates to ((2S,4R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl)methyl carboxylates and a process for the production thereof. Furthermore, the present invention relates to a process for the production of statins and in pa...
|
|
WO/2009/087221A1 |
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C) and/or 2-keto-L-gulonic acid (hereinafter also referred to as ...
|
|
WO/2009/087223A1 |
The present invention relates to novel genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C) and/or 2-keto-L- gulonic acid (hereinafter also referred to as 2-KGA). Th...
|
|
WO/2009/044336A9 |
The present invention provides a method of producing diterpene compounds, said method comprising contacting a particular polypeptide having a diterpene synthase activity with the diterpene precursor geranylgeranyl pyrophosphate (GGPP). I...
|
|
WO/2009/084439A1 |
Disclosed is an enzyme having a lignan-hydroxylating activity, particularly an enzyme capable of catalyzing the reaction for transferring a hydroxy group into a lignan, preferably an enzyme capable of catalyzing the hydroxylation reactio...
|
|
WO/2009/084603A1 |
Disclosed are: enzymes involved in the synthesis of equol; genes respectively encoding the enzymes; and a method for producing equol or an intermediate thereof by using the enzymes. Specifically disclosed are: a dihydrodaidzein synthase,...
|
|
WO/2009/077523A2 |
The present invention provides a method for the fermentative production of compactin, lovastatin, pravastatin and/or simvastatin comprising culturing a mutant host capable of producing said compound wherein esterase activity in said muta...
|
|
WO/2009/073723A1 |
The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the...
|
|
WO/2009/072880A1 |
The invention relates to the field of food, feed and food supplements comprising high folate levels, whereby the folate is produced by fermentation of Lactobacillusstrains on melon fruit extract. Methods for increasing folate production ...
|
|
WO/2009/067784A1 |
An isolated nucleic acid molecule cloned from Artemisia annua encodes an artemisinic aldehyde double bond reductase. Artemisinic aldehyde double bond reductase enzymatically reduces artemisinic aldehyde to (11R)-dihydroartemisinic aldehy...
|
|
WO/2009/069806A1 |
A tetrapyrrole compound having a porphyrin ring structure can be produced by culturing an Escherichia coli cell in a culture medium and collecting the compound from the culture medium, wherein the Escherichia coli cell has a gene ypjD (b...
|
