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Matches 301 - 350 out of 16,987

Document Document Title
WO/2012/092035A1
Disclosed are methods utilizing beta-hydroxy-beta-methylbutyrate (HMB) for facilitating the recovery of muscle after a period of muscle disuse. The HMB facilitates the recovery of muscle mass in an individual and can also be used to prev...  
WO/2012/091571A2
Composition comprising at least two components, more preferably at least three components, more preferably at least four components, selected from the group of (i) a nucleoside equivalent, (ii) an ω-3 polyunsaturated fatty acid selected...  
WO/2012/085586A1
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) pharmaceutical compositions containing such prodrugs. Methods for treating myotonic conditions, while reducing the inherent adverse G1 side effect...  
WO/2012/081570A1
Provided is a lactam compound or a salt thereof indicated by formula (1), which is a compound with a lactam skeleton or a salt thereof useful as a PPAR activator. [In the formula, the ring Z indicates a condensed hydrocarbon ring or a he...  
WO/2012/079057A2
A formulation comprising jasmonate for improving skeletal muscle function in a mammal, particularly a human is provided. This may be accomplished by reducing muscle fatigue and/or increasing skeletal muscle performance.  
WO/2012/079057A3
A formulation comprising jasmonate for improving skeletal muscle function in a mammal, particularly a human is provided. This may be accomplished by reducing muscle fatigue and/or increasing skeletal muscle performance.  
WO/2012/074068A1
Provided is an amplifier for hematopoietic stem cells and/or hematopoietic precursor cells having utility as a therapeutic method against types of hematopoietic disease, and having utility for improving gene transfer efficiency to the he...  
WO/2012/075462A2
The present disclosure provides methods for introducing a gene encoding a muscle membrane protein into a cell isolated from a subject to generate a genetically modified cell. The genetically modified cell may be introduced back, e.g., en...  
WO/2012/068981A1
Disclosed are 6-deoxy-6-thioether-amino acid cyclodextrin derivatives, obtained from condensation of amino acid derivatives with halo-cyclodextrin in the presence of a base. The 6-deoxy-6-thioether-amino acid cyclodextrin derivatives inc...  
WO/2012/067262A1
The present invention provides a therapeutic agent for diseases associated with skeletal muscle degeneration, which comprises a granular colony stimulation factor (G-CSF) as an active ingredient. This therapeutic agent is particularly ef...  
WO/2012/064090A9
The present invention provides a chemical preparation method of skeletal muscle-derived multipotent cells comprising: (a) a step for obtaining differentiated cells from mammals; and (b) a step for obtaining multipotent cells by treating ...  
WO/2012/064090A2
The present invention provides a chemical preparation method of skeletal muscle-derived multipotent cells comprising: (a) a step for obtaining differentiated cells from mammals; and (b) a step for obtaining multipotent cells by treating ...  
WO/2012/064090A3
The present invention provides a chemical preparation method of skeletal muscle-derived multipotent cells comprising: (a) a step for obtaining differentiated cells from mammals; and (b) a step for obtaining multipotent cells by treating ...  
WO/2012/058220A2
The present invention features anti-SODl antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the amelioration of symptoms associated with ALS.  
WO/2012/058220A3
The present invention features anti-SODl antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the amelioration of symptoms associated with ALS.  
WO/2012/054530A2
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory rece...  
WO/2012/053994A2
The present disclosure relates to ecdysteroid analogues which have similar, identical, or enhanced biological activities as compared to brassinosteroids, for instance similar, identical, or enhanced plant growth promoting activity. The e...  
WO/2012/053012A3
The present invention relates to stable pharmaceutical compositions of thiocolchicoside comprising nano size droplets of thiocolchicoside or salts thereof along with other pharmaceutically acceptable excipients. The present invention als...  
WO/2012/054527A2
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory rece...  
WO/2012/054535A2
The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and compositions comprising the same. The invention also relates to methods for treating or p...  
WO/2012/054528A2
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory rece...  
WO/2012/053994A3
The present disclosure relates to ecdysteroid analogues which have similar, identical, or enhanced biological activities as compared to brassinosteroids, for instance similar, identical, or enhanced plant growth promoting activity. The e...  
WO/2012/053012A2
The present invention relates to stable pharmaceutical compositions of thiocolchicoside comprising nano size droplets of thiocolchicoside or salts thereof along with other pharmaceutically acceptable excipients. The present invention als...  
WO/2012/044783A3
The present invention provides embodiments which involve methods of providing a predetermined concentration of thymosin beta 4 (TB4) at a predetermined time, t, in a body portion of a live human patient. The methods can include determini...  
WO/2012/043393A1
[Problem] To provide an emulsion composition, an external skin preparation, and an analgesic, each of which is in a semi-solid state, has excellent thermal stability, and gives a good use sensation when applied to the skin. [Solution] An...  
WO/2012/043808A1
The purpose of the present invention is to provide: a heat shock protein expression inducer capable of inducing the in-vivo expression of HSP; food, drink, a pharmaceutical product, and a cosmetic containing the HSP expression inducer; a...  
WO/2012/039472A1
The purpose of the present invention is to provide a novel method which has an effect of ameliorating central nervous system inflammation. Provided is a drug against central nervous system inflammation which comprises a plasmalogen. Part...  
WO/2012/037083A3
A method of treating a musculoskeletal injury in a subject includes administering directly to a site of the musculoskeletal injury or to an area proximate the musculoskeletal injury an amount of SDF-1, MCP-3, or combinations thereof effe...  
WO/2012/036168A1
A composition that is for treating muscular dystrophy and that contains a SIRT1 activating factor as the active ingredient is provided. The composition may further contain a factor that imports SIRT1 to the nucleus. The present invention...  
WO/2012/034201A3
The present invention relates to a creatine-containing food supplement and method for preparing same. More specifically, the present invention relates to a creatine-containing food supplement formulation compressed into chewable and pala...  
WO/2012/036152A1
The present invention provides a high purity heparin useful as a medicine, a cosmetic, a research reagent and the like, and a production method therefor, in more detail, a method for producing heparin, the method comprising mixing a hepa...  
WO/2012/037083A2
A method of treating a musculoskeletal injury in a subject includes administering directly to a site of the musculoskeletal injury or to an area proximate the musculoskeletal injury an amount of SDF-1, MCP-3, or combinations thereof effe...  
WO/2012/033070A1
[Problem] To provide a pharmaceutical product, especially a pharmaceutical composition which is useful for the treatment of pain. [Solution] The inventors have intensively studied using pain model animals for the purpose of providing a t...  
WO/2012/029994A1
The present invention provides a prophylactic or therapeutic agent for amyotrophic lateral sclerosis, containing a 1,3-diphenylurea derivative or multikinase inhibitor.  
WO/2012/030919A2
The invention provides methods for muscle repair or regeneration comprising administering therapeutically effective amounts of RAR agonists or stem cells that are pretreated with contact with a RAR agonist to a subject at a site of muscl...  
WO/2012/030919A3
The invention provides methods for muscle repair or regeneration comprising administering therapeutically effective amounts of RAR agonists or stem cells that are pretreated with contact with a RAR agonist to a subject at a site of muscl...  
WO/2012/029986A1
Disclosed is a drug which efficiently allows skipping of the 53rd exon in the human dystrophin gene. Disclosed is an oligomer which makes possible skipping of the 53rd exon of the human dystrophin gene.  
WO/2012/027570A2
Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided.  
WO/2012/026575A1
[Problem] The purpose of the present invention is to provide a muscle-enhancing agent. The purpose of the present invention is also to provide food having a muscle-enhancing effect. [Solution] The inventors focused on the effects that Wa...  
WO/2012/024242A1
There are disclosed selective myostatin antagonists (including antibodies), nucleic acids encoding them, and methods of making and using them. Neutralizing antibodies recognizing the conformational epitope near position 21 to 31 and posi...  
WO/2012/019002A2
A population of somatic stem cells and a method of preparing same. Also disclosed are two subpopulations thereof and their various uses.  
WO/2012/019071A1
The present invention provides methods and compositions useful for the treatment and/or prevention of sarcopenia. The compositions include one or more of the following benzothiazepine, benzoxazepine, benzodiazepine or benzazepine compoun...  
WO/2012/019002A3
A population of somatic stem cells and a method of preparing same. Also disclosed are two subpopulations thereof and their various uses.  
WO/2012/016930A1
The present invention relates to the compound of formula (I) for use in the treatment of a nonsense-mutation-mediated genetic disease.  
WO/2012/018257A1
The invention relates to means and methods for removing a proteolytic cleavage site from a protein comprising providing a cell that expresses pre-m RNA encoding said protein with an anti-sense oligonucleotide that induces skipping of the...  
WO/2012/012843A1
The present invention provides novel compounds of the Formula (1), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for modulating Protease A...  
WO/2012/014890A1
Provided are: a nucleic acid molecule capable of binding to c-Met, which is a substance that can be used for analysis of the mechanism of development, diagnosis and treatment of diseases that are induced by c-Met; and use of the nucleic ...  
WO/2012/014994A1
Provided is a compound which can regulate a VCP activity. Specifically provided is a compound represented by formula (I) (wherein R is as defined in the description) or an oxide, ester, prodrug, pharmaceutically acceptable salt or solvat...  
WO/2012/012300A2
Provided herein are methods for ameliorating an adverse effect of systemic administration of a PEG hyaluronan degrading enzyme to a subject. The methods involve systemically administering a PEGylated hyaluronan degrading enzyme, particul...  
WO/2012/011673A3
The present invention relates to a promoter of muscle cell differentiation or renewal, to a pharmaceutical composition for treating or preventing muscular impairment, and to a food composition for alleviating or preventing muscular impai...  

Matches 301 - 350 out of 16,987